Beta-2 transferrin assay in the identification of perilymph

American Journal of Otology

Volumn 20, Issue 2, 1999, Pages 174-178

  Buchman, Craig A ^a   Luxford, William M ^c   Hirsch, Barry E ^d   Fucci, Michael J ^b   Kelly, Robert H ^d  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^b Ear Nose and Throat Associates   (United States)

^c HOUSE EAR INSTITUTE   (United States)

^d UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Beta 2 transferrin; Perilymph; Perilymph fistula; Protein

Indexed keywords

GELFOAM; TRANSFERRIN;

ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN TISSUE; IMMUNOBLOTTING; IMMUNOELECTROPHORESIS; PERILYMPH FISTULA; PRIORITY JOURNAL; PROTEIN DETERMINATION;

COCHLEAR AQUEDUCT; FISTULA; HUMANS; PERILYMPH; RETROSPECTIVE STUDIES; TRANSFERRIN;

EID: 0032866365     PISSN: 01929763     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Weber PC, Hirsch BE. Congenital perilymphatic fistula. In: Myers EN, Bluestone CD, Brackmann DE, Krause CJ, eds. Advances in otolaryngology - head and neck surgery. St. Louis, MO: Mosby-Year Book; 1995:69-81.
2. Meurman OH, Irjala K, Suonpaa J, Laurent B. A new method for the identification of cerebrospinal fluid leakage. Acta Otolaryngol (Stockh) 1979;87:366-9.
3. Irjala K, Suonpaa J, Laurent B. Identification of CSF leakage by immunofixation. Arch Otolaryngol 1979;105:447-8.
4. Fransen P, Sindic CJ, Thauvoy C, Laterre C, Stroobandt G. Highly sensitive detection of beta-2 transferrin in rhinorrhea and otorrhea as a marker for cerebrospinal fluid (C.S.F.) leakage. Acta Neurochir (Wien) 1991;109:98-101.
5. Oberascher G, Arrer E. [Initial clinical experiences with beta-2 transferrin in oto- and rhinorrhea]. HNO 1986;34:151-5.
6. Oberascher G. Cerebrospinal fluid otorrhea - new trends in diagnosis. Am J Otol 1988;9:102-8.
7. Reisinger PW, Hochstrasser K. The diagnosis of CSF fistulae on the basis of detection of beta 2-transferrin by polyacrylamide gel electrophoresis and immunoblotting. J Clin Chem Clin Biochem 1989;27:169-72.
8. Tripathi RC, Millard CB, Tripathi BJ, Noronha A. Tau fraction of transferrin is present in human aqueous humor and is not unique to cerebrospinal fluid. Exp Eye Res 1990;50:541-7.
9. Arrer E, Oberascher G, Gibitz HJ. Protein distribution in the human perilymph. A comparative study between perilymph (post mortem), CSF and blood serum. Acta Otolaryngol (Stockh) 1988;106:117-23.
10. Arrer E, Oberascher G, Gibitz HJ. A map of cochlear perilymph protein based on high-resolution two-dimensional electrophoresis. Eur Arch Otorhinolaryngol 1990;247:271-3.
11. Naiberg JB, Flemming E, Patterson M, Hawke M. The perilymphatic fistula: the end of an enigma? J Otolaryngol 1990;19:260-3.
12. Bassiouny M, Hirsch BE, Kelly RH, Kamerer DB, Cass SP. Beta 2 transferrin application in otology. Am J Otol 1992;13:552-5.
13. Skedros DG, Cass SP, Hirsch BE, Kelly RH. Beta-2 transferrin assay in clinical management of cerebral spinal fluid and perilymphatic fluid leaks. J Otolaryngol 1993;22:341-4.
14. Thalmann I, Kohut RI, Ryu J, Comegys TH, Senarita M, Thalmann R. Protein profile of human perilymph: in search of markers for the diagnosis of perilymph fistula and other inner ear disease. Otolaryngol Head Neck Surg 1994;111:273-80.
15. Delaroche O, Bordure P, Lippert E, Sagniez M. Perilymph detection by beta 2-transferrin immunoblotting assay. Application to the diagnosis of perilymphatic fistulae. Clin Chim Acta 1996;245:93-104.
16. Thomsen J, Saxtrup O, Tos M. Quantitated determination of proteins in perilymph in patients with acoustic neuromas. ORL J Otorhinolaryngol Relat Spec 1982;44:61-5.
17. Rasmussen N, Bendtzen K, Thomsen J, Tos M. Antigenicity and protein content of perilymph in acoustic neuroma patients. Acta Otolaryngol (Stockh) 1984;97:502-8.
18. Levenson MJ, Desloge RB, Parisier SC. Beta-2 transferrin: Limitations of use as a clinical marker for perilymph. Laryngoscope 1996;106:159-61.
19. Silverstein H. Rapid protein test for perilymph fistula. Otolaryngol Head Neck Surg 1991;105:422-6.
20. Woodson BT, Fujita S, Mawhinney TP, Schweitzer VG, Peterson EL. Perilymphatic fistula: Analysis of free amino acids in middle ear microaspirates. Otolaryngol Head Neck Surg 1991;104:796-802.