메뉴 건너뛰기




Volumn 158, Issue 1, 1999, Pages 109-120

Glutamate and antimitotic agents induce differentiation, p53 activation, and apoptosis in rodent neostriatal cell lines immortalized with the tsA58 allele of SV40 large T antigen

Author keywords

Apoptosis p53; Cell lines; PC12 cell; SV40 large T antigen

Indexed keywords

ANTIMITOTIC AGENT; CYTARABINE; DOXORUBICIN; GLUTAMIC ACID; PROTEIN P53; VIRUS LARGE T ANTIGEN;

EID: 0032866259     PISSN: 00144886     EISSN: None     Source Type: Journal    
DOI: 10.1006/exnr.1999.7083     Document Type: Article
Times cited : (7)

References (90)
  • 1
    • 0026575901 scopus 로고
    • Camptothecin induces differentiation and stimulates the expression of differentiation-related genes in U-937 human promonocytic leukemia cells
    • Aller P., Rius C., Mata F., Zorrilla A., Cabanas C., Bellon T., Bernabeu C. Camptothecin induces differentiation and stimulates the expression of differentiation-related genes in U-937 human promonocytic leukemia cells. Cancer Res. 52:1992;1245-1251.
    • (1992) Cancer Res. , vol.52 , pp. 1245-1251
    • Aller, P.1    Rius, C.2    Mata, F.3    Zorrilla, A.4    Cabanas, C.5    Bellon, T.6    Bernabeu, C.7
  • 3
    • 0017069189 scopus 로고
    • The effect of Adriamycin on the cell cycle traverse of a human lymphoid cell line
    • Barlogie B., Drewinko B., Johnston D. A., Freireich E. J. The effect of Adriamycin on the cell cycle traverse of a human lymphoid cell line. Cancer Res. 36:1976;1975-1979.
    • (1976) Cancer Res. , vol.36 , pp. 1975-1979
    • Barlogie, B.1    Drewinko, B.2    Johnston, D.A.3    Freireich, E.J.4
  • 4
    • 0027617675 scopus 로고
    • Butyrate rapidly induces growth inhibition and differentiation in HT-29 cells
    • Barnard J. A., Warwick G. Butyrate rapidly induces growth inhibition and differentiation in HT-29 cells. Cell Growth Differ. 4:1993;495-501.
    • (1993) Cell Growth Differ. , vol.4 , pp. 495-501
    • Barnard, J.A.1    Warwick, G.2
  • 5
    • 0023691409 scopus 로고
    • Verapamil reversal of doxorubicin resistance in multidrug-resistant human myeloma cells and association with drug accumulation and DNA damage
    • Bellamy W. T., Dalton W. S., Kailey J. M., Gleason M. C., McCloskey T. M., Dorr R. T., Alberts D. S. Verapamil reversal of doxorubicin resistance in multidrug-resistant human myeloma cells and association with drug accumulation and DNA damage. Cancer Res. 48:1988;6365-6370.
    • (1988) Cancer Res. , vol.48 , pp. 6365-6370
    • Bellamy, W.T.1    Dalton, W.S.2    Kailey, J.M.3    Gleason, M.C.4    McCloskey, T.M.5    Dorr, R.T.6    Alberts, D.S.7
  • 6
    • 0022853614 scopus 로고
    • Terminal erythroid differentiation in the K-562 cell line by 1-beta-D-arabinofuranosylcytosine: Accompaniment by c-myc messenger RNA decrease
    • Bianchi Scarra G. L., Romani M., Coviello D. A., Garre C., Ravazzolo R., Vidali G., Ajmar F. Terminal erythroid differentiation in the K-562 cell line by 1-beta-D-arabinofuranosylcytosine: Accompaniment by c-myc messenger RNA decrease. Cancer Res. 46:1986;6327-6332.
    • (1986) Cancer Res. , vol.46 , pp. 6327-6332
    • Bianchi Scarra, G.L.1    Romani, M.2    Coviello, D.A.3    Garre, C.4    Ravazzolo, R.5    Vidali, G.6    Ajmar, F.7
  • 7
    • 0029658148 scopus 로고    scopus 로고
    • The CDK inhibitor p21WAF1/Cip1 is induced through a p300-dependent mechanism during NGF-mediated neuronal differentiation of PC12 cells
    • Billon N., van Grunsven L. A., Rudkin B. B. The CDK inhibitor p21WAF1/Cip1 is induced through a p300-dependent mechanism during NGF-mediated neuronal differentiation of PC12 cells. Oncogene. 13:1996;2047-2054.
    • (1996) Oncogene , vol.13 , pp. 2047-2054
    • Billon, N.1    Van Grunsven, L.A.2    Rudkin, B.B.3
  • 9
    • 0025690504 scopus 로고
    • Adriamycin effects on hydroperoxide metabolism and growth of human breast tumor cells
    • Bustamante J., Galleano M., Medrano E. E., Boveris A. Adriamycin effects on hydroperoxide metabolism and growth of human breast tumor cells. Breast Cancer Res. Treat. 17:1990;145-153.
    • (1990) Breast Cancer Res. Treat. , vol.17 , pp. 145-153
    • Bustamante, J.1    Galleano, M.2    Medrano, E.E.3    Boveris, A.4
  • 10
    • 0025363503 scopus 로고
    • Induction of differentiation and DNA strand breakage in human HL-60 and K-562 leukemia cells by genistein
    • Constantinou A., Kiguchi K., Huberman E. Induction of differentiation and DNA strand breakage in human HL-60 and K-562 leukemia cells by genistein. Cancer Res. 50:1990;2618-2624.
    • (1990) Cancer Res. , vol.50 , pp. 2618-2624
    • Constantinou, A.1    Kiguchi, K.2    Huberman, E.3
  • 13
    • 0031890993 scopus 로고    scopus 로고
    • N18-RE-105 cells: Differentiation and activation of p53 in response to glutamate and Adriamycin is blocked by SV40 large T antigen tsA58
    • Dillon-Carter O., Conejero C., Tornatore C., Poltorak M., Freed W. N18-RE-105 cells: Differentiation and activation of p53 in response to glutamate and Adriamycin is blocked by SV40 large T antigen tsA58. Cell Tissue Res. 291:1998;191-205.
    • (1998) Cell Tissue Res. , vol.291 , pp. 191-205
    • Dillon-Carter, O.1    Conejero, C.2    Tornatore, C.3    Poltorak, M.4    Freed, W.5
  • 17
    • 0029395054 scopus 로고
    • Life and death by p53
    • Elledge R. M., Lee W. H. Life and death by p53. Bioessays. 17:1995;923-930.
    • (1995) Bioessays , vol.17 , pp. 923-930
    • Elledge, R.M.1    Lee, W.H.2
  • 18
    • 0026568779 scopus 로고
    • Immortal rat hippocampal cell lines exhibit neuronal and glial lineages and neurotrophin gene expression
    • Eves E. M., Tucker M. S., Roback J. D., Downen M., Rosner M. R., Wainer B. H. Immortal rat hippocampal cell lines exhibit neuronal and glial lineages and neurotrophin gene expression. Proc. Natl. Acad. Sci. USA. 89:1992;4373-4377.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 4373-4377
    • Eves, E.M.1    Tucker, M.S.2    Roback, J.D.3    Downen, M.4    Rosner, M.R.5    Wainer, B.H.6
  • 20
    • 0026660344 scopus 로고
    • Expression of the normal p53 gene induces differentiation of K562 cells
    • Feinstein E., Gale R. P., Reed J., Canaani E. Expression of the normal p53 gene induces differentiation of K562 cells. Oncogene. 7:1992;1853-1857.
    • (1992) Oncogene , vol.7 , pp. 1853-1857
    • Feinstein, E.1    Gale, R.P.2    Reed, J.3    Canaani, E.4
  • 21
    • 0026722361 scopus 로고
    • Lack of involvement of reactive oxygen in the cytotoxicity of mitoxantrone, CI941 and ametantrone in MCF-7 cells: Comparison with doxorubicin
    • Fisher G. R., Patterson L. H. Lack of involvement of reactive oxygen in the cytotoxicity of mitoxantrone, CI941 and ametantrone in MCF-7 cells: Comparison with doxorubicin. Cancer Chemother. Pharmacol. 30:1992;451-458.
    • (1992) Cancer Chemother. Pharmacol. , vol.30 , pp. 451-458
    • Fisher, G.R.1    Patterson, L.H.2
  • 23
    • 0028129285 scopus 로고
    • Induction of differentiation and growth arrest associated with nascent (nonoligosomal) DNA fragmentation and reduced c-myc expression in MCF-7 human breast tumor cells after continuous exposure to a sublethal concentration of doxorubicin
    • Fornari F. A. Jr., Jarvis W. D., Grant S., Orr M. S., Randolph J. K., White F. K., Mumaw V. R., Lovings E. T., Freeman R. H., Gewirtz D. A. Induction of differentiation and growth arrest associated with nascent (nonoligosomal) DNA fragmentation and reduced c-myc expression in MCF-7 human breast tumor cells after continuous exposure to a sublethal concentration of doxorubicin. Cell Growth Differ. 5:1994;723-733.
    • (1994) Cell Growth Differ. , vol.5 , pp. 723-733
    • Fornari F.A., Jr.1    Jarvis, W.D.2    Grant, S.3    Orr, M.S.4    Randolph, J.K.5    White, F.K.6    Mumaw, V.R.7    Lovings, E.T.8    Freeman, R.H.9    Gewirtz, D.A.10
  • 25
    • 0024057953 scopus 로고
    • Immortalization of precursor cells from the mammalian CNS
    • Frederiksen K., Jat P. S., Valtz N., Levy D., McKay R. Immortalization of precursor cells from the mammalian CNS. Neuron. 1:1988;439-448.
    • (1988) Neuron , vol.1 , pp. 439-448
    • Frederiksen, K.1    Jat, P.S.2    Valtz, N.3    Levy, D.4    McKay, R.5
  • 28
    • 0023807773 scopus 로고
    • Antigenic and functional characterization of a rat central nervous system-derived cell line immortalized by a retroviral vector
    • Geller H. M., Dubois-Dalcq M. Antigenic and functional characterization of a rat central nervous system-derived cell line immortalized by a retroviral vector. J. Cell. Biol. 107:1988;1977-1986.
    • (1988) J. Cell. Biol. , vol.107 , pp. 1977-1986
    • Geller, H.M.1    Dubois-Dalcq, M.2
  • 29
    • 0027769488 scopus 로고
    • Immortalized GABAergic cell lines derived from rat striatum using a temperature-sensitive allele of the SV40 large T antigen
    • Giordano M., Takashima H., Herranz A., Poltorak M., Geller H. M., Marone M., Freed W. J. Immortalized GABAergic cell lines derived from rat striatum using a temperature-sensitive allele of the SV40 large T antigen. Exp. Neurol. 124:1993;395-400.
    • (1993) Exp. Neurol. , vol.124 , pp. 395-400
    • Giordano, M.1    Takashima, H.2    Herranz, A.3    Poltorak, M.4    Geller, H.M.5    Marone, M.6    Freed, W.J.7
  • 30
    • 0029766815 scopus 로고    scopus 로고
    • Constitutive expression of glutamic acid decarboxylase (GAD) by striatal cell lines immortalized using the tsA58 allele of the SV40 large T antigen
    • Giordano M., Takashima H., Poltorak M., Geller H. M., Freed W. J. Constitutive expression of glutamic acid decarboxylase (GAD) by striatal cell lines immortalized using the tsA58 allele of the SV40 large T antigen. Cell Transplant. 5:1996;563-575.
    • (1996) Cell Transplant. , vol.5 , pp. 563-575
    • Giordano, M.1    Takashima, H.2    Poltorak, M.3    Geller, H.M.4    Freed, W.J.5
  • 31
    • 0022537056 scopus 로고
    • Resistance to Adriamycin: Relationship of cytotoxicity to drug uptake and DNA single- And double-strand breakage in cloned cell lines of Adriamycin-sensitive and -resistant P388 leukemia
    • Goldenberg G. J., Wang H., Blair G. W. Resistance to Adriamycin: Relationship of cytotoxicity to drug uptake and DNA single- and double-strand breakage in cloned cell lines of Adriamycin-sensitive and -resistant P388 leukemia. Cancer Res. 46:1986;2978-2983.
    • (1986) Cancer Res. , vol.46 , pp. 2978-2983
    • Goldenberg, G.J.1    Wang, H.2    Blair, G.W.3
  • 33
    • 0026573505 scopus 로고
    • Differentiation and retrodifferentiation of human myeloid leukemia cells is associated with reversible induction of cell cycle-regulatory genes
    • Hass R., Gunji H., Datta R., Kharbanda S., Hartmann A., Weichselbaum R., Kufe D. Differentiation and retrodifferentiation of human myeloid leukemia cells is associated with reversible induction of cell cycle-regulatory genes. Cancer Res. 52:1992;1445-1450.
    • (1992) Cancer Res. , vol.52 , pp. 1445-1450
    • Hass, R.1    Gunji, H.2    Datta, R.3    Kharbanda, S.4    Hartmann, A.5    Weichselbaum, R.6    Kufe, D.7
  • 36
    • 0027989728 scopus 로고
    • Fundamentals of chemo-differentiation therapy of myeloid leukemia
    • Hozumi M. Fundamentals of chemo-differentiation therapy of myeloid leukemia. Anticancer Res. 14:1994;1177-1192.
    • (1994) Anticancer Res. , vol.14 , pp. 1177-1192
    • Hozumi, M.1
  • 37
    • 0024592630 scopus 로고
    • Cell lines established by a temperature-sensitive simian virus 40 large-T-antigen gene are growth restricted at the nonpermissive temperature
    • Jat P. S., Sharp P. A. Cell lines established by a temperature-sensitive simian virus 40 large-T-antigen gene are growth restricted at the nonpermissive temperature. Mol. Cell. Biol. 9:1989;1672-1681.
    • (1989) Mol. Cell. Biol. , vol.9 , pp. 1672-1681
    • Jat, P.S.1    Sharp, P.A.2
  • 38
    • 0027536952 scopus 로고
    • Growth suppression of Friend virus-transformed erythroleukemia cells by p53 protein is accompanied by hemoglobin production and is sensitive to erythropoietin
    • Johnson P., Chung S., Benchimol S. Growth suppression of Friend virus-transformed erythroleukemia cells by p53 protein is accompanied by hemoglobin production and is sensitive to erythropoietin. Mol. Cell. Biol. 13:1993;1456-1463.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 1456-1463
    • Johnson, P.1    Chung, S.2    Benchimol, S.3
  • 40
    • 0020506009 scopus 로고
    • Induction of differentiation of human acute myelogenous leukemia cells: Therapeutic implications
    • Koeffler H. P. Induction of differentiation of human acute myelogenous leukemia cells: Therapeutic implications. Blood. 62:1983;709-721.
    • (1983) Blood , vol.62 , pp. 709-721
    • Koeffler, H.P.1
  • 43
    • 0028234673 scopus 로고
    • Up-regulation of a mutant form of p53 by doxorubicin in human squamous carcinoma cells
    • Kwok T. T., Mok C. H., Menton-Brennan L. Up-regulation of a mutant form of p53 by doxorubicin in human squamous carcinoma cells. Cancer Res. 54:1994;2834-2836.
    • (1994) Cancer Res. , vol.54 , pp. 2834-2836
    • Kwok, T.T.1    Mok, C.H.2    Menton-Brennan, L.3
  • 44
    • 0018348655 scopus 로고
    • T antigen is bound to a host protein in SV40-transformed cells
    • Lane D. P., Crawford L. V. T antigen is bound to a host protein in SV40-transformed cells. Nature. 278:1979;261-263.
    • (1979) Nature , vol.278 , pp. 261-263
    • Lane, D.P.1    Crawford, L.V.2
  • 45
    • 0025333586 scopus 로고
    • DNA synthesis by L929 cells following doxorubicin exposure
    • Lanks K. W., Lehman J. M. DNA synthesis by L929 cells following doxorubicin exposure. Cancer Res. 50:1990;4776-4778.
    • (1990) Cancer Res. , vol.50 , pp. 4776-4778
    • Lanks, K.W.1    Lehman, J.M.2
  • 47
    • 0027451668 scopus 로고
    • P53-dependent apoptosis modulates the cytotoxicity of anticancer agents
    • Lowe S. W., Ruley H. E., Jacks T., Housman D. E. p53-dependent apoptosis modulates the cytotoxicity of anticancer agents. Cell. 74:1993;957-967.
    • (1993) Cell , vol.74 , pp. 957-967
    • Lowe, S.W.1    Ruley, H.E.2    Jacks, T.3    Housman, D.E.4
  • 48
    • 0029894942 scopus 로고    scopus 로고
    • Use of sequential immunoprecipitation to reveal discrete, separable populations of SV40 T-antigen binding to host cellular proteins
    • Ludlow J. W. Use of sequential immunoprecipitation to reveal discrete, separable populations of SV40 T-antigen binding to host cellular proteins. J. Virol. Methods. 59:1996;105-112.
    • (1996) J. Virol. Methods , vol.59 , pp. 105-112
    • Ludlow, J.W.1
  • 50
    • 0025288204 scopus 로고
    • Morphological alterations induced by doxorubicin in B16 melanoma cells
    • Mariani M., Supino R. Morphological alterations induced by doxorubicin in B16 melanoma cells. Cancer Lett. 51:1990;209-212.
    • (1990) Cancer Lett. , vol.51 , pp. 209-212
    • Mariani, M.1    Supino, R.2
  • 54
    • 0025017561 scopus 로고
    • Cytosine arabinoside kills postmitotic neurons in a fashion resembling trophic factor deprivation: Evidence that a deoxycytidine-dependent process may be required for nerve growth factor signal transduction
    • Martin D. P., Wallace T. L., Johnson E. M. Jr. Cytosine arabinoside kills postmitotic neurons in a fashion resembling trophic factor deprivation: Evidence that a deoxycytidine-dependent process may be required for nerve growth factor signal transduction. J. Neurosci. 10:1990;184-193.
    • (1990) J. Neurosci. , vol.10 , pp. 184-193
    • Martin, D.P.1    Wallace, T.L.2    Johnson E.M., Jr.3
  • 56
    • 0017178490 scopus 로고
    • Effect of adriamycin on DNA, RNA, and protein synthesis in cell-free systems and intact cells
    • Momparler R. L., Karon M., Siegel S. E., Avila F. Effect of adriamycin on DNA, RNA, and protein synthesis in cell-free systems and intact cells. Cancer Res. 36:1976;2891-2895.
    • (1976) Cancer Res. , vol.36 , pp. 2891-2895
    • Momparler, R.L.1    Karon, M.2    Siegel, S.E.3    Avila, F.4
  • 57
    • 0022639538 scopus 로고
    • Two simian virus 40 (SV40)-transformed cell lines from the mouse striatum and mesencephalon presenting astrocytic characters. I. Immunological and pharmacological properties
    • Moura Neto V., Mallat M., Chneiweiss H., Premont J., Gros F., Prochiantz A. Two simian virus 40 (SV40)-transformed cell lines from the mouse striatum and mesencephalon presenting astrocytic characters. I. Immunological and pharmacological properties. Brain Res. 391:1986;11-22.
    • (1986) Brain Res. , vol.391 , pp. 11-22
    • Moura Neto, V.1    Mallat, M.2    Chneiweiss, H.3    Premont, J.4    Gros, F.5    Prochiantz, A.6
  • 58
    • 0025975299 scopus 로고
    • Topoisomerase inhibitors have potent differentiation-inducing activity for human and mouse myeloid leukemia cells
    • Nakaya K., Chou S., Kaneko M., Nakamura Y. Topoisomerase inhibitors have potent differentiation-inducing activity for human and mouse myeloid leukemia cells. Jpn. J. Cancer Res. 82:1991;184-191.
    • (1991) Jpn. J. Cancer Res. , vol.82 , pp. 184-191
    • Nakaya, K.1    Chou, S.2    Kaneko, M.3    Nakamura, Y.4
  • 59
    • 0028927887 scopus 로고
    • Constitutive expression of the c-H-ras oncogene inhibits doxorubicin-induced apoptosis and promotes cell survival in a rhabdomyosarcoma cell line
    • Nooter K., Boersma A. W., Oostrum R. G., Burger H., Jochemsen A. G., Stoter G. Constitutive expression of the c-H-ras oncogene inhibits doxorubicin-induced apoptosis and promotes cell survival in a rhabdomyosarcoma cell line. Br. J. Cancer. 71:1995;556-561.
    • (1995) Br. J. Cancer , vol.71 , pp. 556-561
    • Nooter, K.1    Boersma, A.W.2    Oostrum, R.G.3    Burger, H.4    Jochemsen, A.G.5    Stoter, G.6
  • 60
    • 0024473604 scopus 로고
    • G1 events and regulation of cell proliferation
    • Pardee A. B. G1 events and regulation of cell proliferation. Science. 246:1989;603-608.
    • (1989) Science , vol.246 , pp. 603-608
    • Pardee, A.B.1
  • 61
    • 0027964904 scopus 로고
    • Immunochemical analysis of the interaction of p53 with MDM2; - Fine mapping of the MDM2 binding site on p53 using synthetic peptides
    • Picksley S. M., Vojtesek B., Sparks A., Lane D. P. Immunochemical analysis of the interaction of p53 with MDM2; - Fine mapping of the MDM2 binding site on p53 using synthetic peptides. Oncogene. 9:1994;2523-2529.
    • (1994) Oncogene , vol.9 , pp. 2523-2529
    • Picksley, S.M.1    Vojtesek, B.2    Sparks, A.3    Lane, D.P.4
  • 63
    • 0022572837 scopus 로고
    • Induction of tumor cell differentiation as a therapeutic approach: Preclinical models for hematopoietic and solid neoplasms
    • Reiss M., Gamba-Vitalo C., Sartorelli A. C. Induction of tumor cell differentiation as a therapeutic approach: Preclinical models for hematopoietic and solid neoplasms. Cancer Treat. Rep. 70:1986;201-218.
    • (1986) Cancer Treat. Rep. , vol.70 , pp. 201-218
    • Reiss, M.1    Gamba-Vitalo, C.2    Sartorelli, A.C.3
  • 64
    • 0027157628 scopus 로고
    • Aurintricarboxylic acid protects hippocampal neurons from NMDA- And ischemia-induced toxicity in vivo
    • Roberts-Lewis J. M., Marcy V. R., Zhao Y., Vaught J. L., Siman R., Lewis M. E. Aurintricarboxylic acid protects hippocampal neurons from NMDA- and ischemia-induced toxicity in vivo. J. Neurochem. 61:1993;378-381.
    • (1993) J. Neurochem. , vol.61 , pp. 378-381
    • Roberts-Lewis, J.M.1    Marcy, V.R.2    Zhao, Y.3    Vaught, J.L.4    Siman, R.5    Lewis, M.E.6
  • 65
    • 0030031757 scopus 로고    scopus 로고
    • Induction of HL-60 cells to undergo apoptosis is determined by high levels of wild-type p53 protein whereas differentiation of the cells is mediated by lower p53 levels
    • Ronen D., Schwartz D., Teitz Y., Goldfinger N., Rotter V. Induction of HL-60 cells to undergo apoptosis is determined by high levels of wild-type p53 protein whereas differentiation of the cells is mediated by lower p53 levels. Cell Growth Differ. 7:1996;21-30.
    • (1996) Cell Growth Differ. , vol.7 , pp. 21-30
    • Ronen, D.1    Schwartz, D.2    Teitz, Y.3    Goldfinger, N.4    Rotter, V.5
  • 66
    • 0025270335 scopus 로고
    • Effects of 1-beta-D-arabinofuranosylcytosine on DNA replication intermediates monitored by pH-step alkaline elution
    • Ross D. D., Chen S. R., Cuddy D. P. Effects of 1-beta-D-arabinofuranosylcytosine on DNA replication intermediates monitored by pH-step alkaline elution. Cancer Res. 50:1990;2658-2666.
    • (1990) Cancer Res. , vol.50 , pp. 2658-2666
    • Ross, D.D.1    Chen, S.R.2    Cuddy, D.P.3
  • 68
    • 0025237864 scopus 로고
    • Establishment and characterization of multipotent neural cell lines using retrovirus vector-mediated oncogene transfer
    • Ryder E. F., Snyder E. Y., Cepko C. L. Establishment and characterization of multipotent neural cell lines using retrovirus vector-mediated oncogene transfer. J. Neurobiol. 21:1990;356-375.
    • (1990) J. Neurobiol. , vol.21 , pp. 356-375
    • Ryder, E.F.1    Snyder, E.Y.2    Cepko, C.L.3
  • 69
    • 0023236123 scopus 로고
    • Cell differentiation and bypassing of genetic defects in the suppression of malignancy
    • Sachs L. Cell differentiation and bypassing of genetic defects in the suppression of malignancy. Cancer Res. 47:1987;1981-1986.
    • (1987) Cancer Res. , vol.47 , pp. 1981-1986
    • Sachs, L.1
  • 70
    • 0029591557 scopus 로고
    • Induction of differentiation in erythroleukemic K562 cells by gamma-irradiation
    • Schwenke K., Peterson H. P., Wangenheim K. H., Feinendegen L. E. Induction of differentiation in erythroleukemic K562 cells by gamma-irradiation. Leukocyte Res. 19:1995;955-961.
    • (1995) Leukocyte Res. , vol.19 , pp. 955-961
    • Schwenke, K.1    Peterson, H.P.2    Wangenheim, K.H.3    Feinendegen, L.E.4
  • 72
    • 0027237540 scopus 로고
    • Adriamycin and daunomycin induce programmed cell death (apoptosis) in tumour cells
    • Skladanowski A., Konopa J. Adriamycin and daunomycin induce programmed cell death (apoptosis) in tumour cells. Biochem. Pharmacol. 46:1993;375-382.
    • (1993) Biochem. Pharmacol. , vol.46 , pp. 375-382
    • Skladanowski, A.1    Konopa, J.2
  • 74
    • 0030031998 scopus 로고    scopus 로고
    • A cellular protein activates the sequence-specific DNA-binding of p53 by interacting with the central conserved region
    • Srinivasan R., Maxwell S. A. A cellular protein activates the sequence-specific DNA-binding of p53 by interacting with the central conserved region. Oncogene. 12:1996;193-200.
    • (1996) Oncogene , vol.12 , pp. 193-200
    • Srinivasan, R.1    Maxwell, S.A.2
  • 75
    • 0026588345 scopus 로고
    • Comparative studies on the effects of doxorubicin and differentiation inducing agents on B16 melanoma cells
    • Supino R., Mariani M., Colombo A., Prosperi E., Croce A. C., Bottiroli G. Comparative studies on the effects of doxorubicin and differentiation inducing agents on B16 melanoma cells. Eur. J. Cancer. 28A:1992;778-783.
    • (1992) Eur. J. Cancer , vol.28 , pp. 778-783
    • Supino, R.1    Mariani, M.2    Colombo, A.3    Prosperi, E.4    Croce, A.C.5    Bottiroli, G.6
  • 76
    • 0029125370 scopus 로고
    • Properties of incompletely immortalized cell lines generated from a line established from temperature-sensitive SV40 T-antigen gene transgenic mice
    • Taher A., Yanai N., Obinata M. Properties of incompletely immortalized cell lines generated from a line established from temperature-sensitive SV40 T-antigen gene transgenic mice. Exp. Cell. Res. 219:1995;332-338.
    • (1995) Exp. Cell. Res. , vol.219 , pp. 332-338
    • Taher, A.1    Yanai, N.2    Obinata, M.3
  • 77
    • 0015134772 scopus 로고
    • Temperature-sensitive mutants of simian virus 40: Infection of permissive cells
    • Tegtmeyer P., Ozer H. L. Temperature-sensitive mutants of simian virus 40: Infection of permissive cells. J. Virol. 8:1971;516-524.
    • (1971) J. Virol. , vol.8 , pp. 516-524
    • Tegtmeyer, P.1    Ozer, H.L.2
  • 78
    • 0021151237 scopus 로고
    • Adriamycin-induced DNA damage mediated by mammalian DNA topoisomerase II
    • Tewey K. M., Rowe T. C., Yang L., Halligan B. D., Liu L. F. Adriamycin-induced DNA damage mediated by mammalian DNA topoisomerase II. Science. 226:1984;466-468.
    • (1984) Science , vol.226 , pp. 466-468
    • Tewey, K.M.1    Rowe, T.C.2    Yang, L.3    Halligan, B.D.4    Liu, L.F.5
  • 79
    • 0024537596 scopus 로고
    • In K562 leukemia cells treated with doxorubicin and hemin, a decrease in c-myc mRNA expression correlates with loss of self-renewal capability but not with erythroid differentiation
    • Toffoli G., Viel A., Bevilacqua C., Maestro R., Tumiotto L., Boiocchi M. In K562 leukemia cells treated with doxorubicin and hemin, a decrease in c-myc mRNA expression correlates with loss of self-renewal capability but not with erythroid differentiation. Leukocyte Res. 13:1989;279-287.
    • (1989) Leukocyte Res. , vol.13 , pp. 279-287
    • Toffoli, G.1    Viel, A.2    Bevilacqua, C.3    Maestro, R.4    Tumiotto, L.5    Boiocchi, M.6
  • 80
    • 0028206102 scopus 로고
    • Apoptosis is induced in post-mitotic rat sympathetic neurons by arabinosides and topoisomerase II inhibitors in the presence of NGF
    • Tomkins C. E., Edwards S. N., Tolkovsky A. M. Apoptosis is induced in post-mitotic rat sympathetic neurons by arabinosides and topoisomerase II inhibitors in the presence of NGF. J. Cell Sci. 107:1994;1499-1507.
    • (1994) J. Cell Sci. , vol.107 , pp. 1499-1507
    • Tomkins, C.E.1    Edwards, S.N.2    Tolkovsky, A.M.3
  • 81
    • 0031889823 scopus 로고    scopus 로고
    • A truncated SV40 large T antigen lacking the p53 binding domain overcomes p53-induced growth arrest and immortalizes primary mesencephalic cells
    • Truckenmiller M. E., Tornatore C., Wright R. D., Dillon-Carter O., Meiners S., Geller H. M., Freed W. J. A truncated SV40 large T antigen lacking the p53 binding domain overcomes p53-induced growth arrest and immortalizes primary mesencephalic cells. Cell Tissue Res. 291:1998;175-189.
    • (1998) Cell Tissue Res. , vol.291 , pp. 175-189
    • Truckenmiller, M.E.1    Tornatore, C.2    Wright, R.D.3    Dillon-Carter, O.4    Meiners, S.5    Geller, H.M.6    Freed, W.J.7
  • 83
    • 0025711796 scopus 로고
    • Cancer. A deadly inheritance [news; Comment]
    • Vogelstein B. Cancer. A deadly inheritance [news; comment]. Nature. 348:1990;681-682.
    • (1990) Nature , vol.348 , pp. 681-682
    • Vogelstein, B.1
  • 84
    • 0026669469 scopus 로고
    • P53 function and dysfunction
    • Vogelstein B., Kinzler K. W. p53 function and dysfunction. Cell. 70:1992;523-526.
    • (1992) Cell , vol.70 , pp. 523-526
    • Vogelstein, B.1    Kinzler, K.W.2
  • 85
    • 0028274097 scopus 로고
    • Differentiation of an immortalized CNS neuronal cell line decreases their susceptibility to cytotoxic T cell lysis in vitro
    • White L. A., Keane R. W., Whittemore S. R. Differentiation of an immortalized CNS neuronal cell line decreases their susceptibility to cytotoxic T cell lysis in vitro. J. Neuroimmunol. 49:1994;135-143.
    • (1994) J. Neuroimmunol. , vol.49 , pp. 135-143
    • White, L.A.1    Keane, R.W.2    Whittemore, S.R.3
  • 86
    • 0028390753 scopus 로고
    • Isolation and characterization of conditionally immortalized astrocyte cell lines derived from adult human spinal cord
    • Whittemore S. R., Neary J. T., Kleitman N., Sanon H. R., Benigno A., Donahue R. P., Norenberg M. D. Isolation and characterization of conditionally immortalized astrocyte cell lines derived from adult human spinal cord. Glia. 10:1994;211-226.
    • (1994) Glia , vol.10 , pp. 211-226
    • Whittemore, S.R.1    Neary, J.T.2    Kleitman, N.3    Sanon, H.R.4    Benigno, A.5    Donahue, R.P.6    Norenberg, M.D.7
  • 87
    • 0027207697 scopus 로고
    • Target regulation of neuronal differentiation in a temperature-sensitive cell line derived from medullary raphe
    • Whittemore S. R., White L. A. Target regulation of neuronal differentiation in a temperature-sensitive cell line derived from medullary raphe. Brain Res. 615:1993;27-40.
    • (1993) Brain Res. , vol.615 , pp. 27-40
    • Whittemore, S.R.1    White, L.A.2
  • 88
    • 0018743824 scopus 로고
    • Evidence for a new mechanism of cytotoxicity of 1-beta-D-arabinofuranosylcytosine
    • Woodcock D. M., Fox R. M., Cooper I. A. Evidence for a new mechanism of cytotoxicity of 1-beta-D-arabinofuranosylcytosine. Cancer Res. 39:1979;1418-1424.
    • (1979) Cancer Res. , vol.39 , pp. 1418-1424
    • Woodcock, D.M.1    Fox, R.M.2    Cooper, I.A.3
  • 90
    • 0029052834 scopus 로고
    • NGF regulates the PC12 cell cycle machinery through specific inhibition of the Cdk kinases and induction of cyclin D1
    • Yan G. Z., Ziff E. B. NGF regulates the PC12 cell cycle machinery through specific inhibition of the Cdk kinases and induction of cyclin D1. J. Neurosci. 15:1995;6200-6212.
    • (1995) J. Neurosci. , vol.15 , pp. 6200-6212
    • Yan, G.Z.1    Ziff, E.B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.