Parasympathetic inhibition of sympathetic effects on pacemaker location and rate in hearts of anesthetized dogs

Journal of Cardiovascular Electrophysiology

Volumn 10, Issue 8, 1999, Pages 1066-1076

  Miyashita, Yusuke ^a   Furukawa, Yasuyuki ^a   Nakajima, Koichi ^a   Hirose, Masamichi ^a   Kurogouchi, Fumio ^a   Chiba, Shigetoshi ^a  

^a SHINSHU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Atrial pacemaker complex; Heart rate; Pacemaker site; Sinoatrial node; Sympathetic parasympathetic interaction

Indexed keywords

ATROPINE; PROPRANOLOL;

ADRENERGIC STIMULATION; ADRENERGIC SYSTEM; ARTICLE; CHOLINERGIC SYSTEM; DOG; HEART RATE; HEART RIGHT ATRIUM; NONHUMAN; PRIORITY JOURNAL; SINUS NODE; VAGUS NERVE STIMULATION;

EID: 0032865654     PISSN: 10453873     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1540-8167.1999.tb00279.x     Document Type: Article

References (27)

1. 1. Samaan A: The antagonistic cardiac nerves and heart rate. J Physiol (Lond) 1935;83:332-340.
2. 2. Levy MN, Zieske H: Autonomic control of cardiac pacemaker activity and atrioventricular transmission, J Appl Physiol 1969;27:465-470.
3. 3. Warner HR, Russel RO Jr: Effect of combined sympathetic and vagal stimulation on heart rate in the dog. Circ Res 1969;24:567-573.
4. 4. Levy MN: Autonomic interactions in cardiac control. In Coumel P, Garfein OB, eds. Electrocardiography. Volume 601. New York Academy of Science, New York, 1990. pp. 209-221.
5. 5. McGuirt AS, Schmacht DC, Ardell JL: Autonomic interactions for control of atrial rate are maintained after SA nodal parasympathectomy. Am J Physiol 1997;272:H2525-H2533.
6. 6. Endoh M, Maruyama M, Iijima T: Attenuation of muscarinic cholinergic inhibition by islet-activating protein in the heart. Am J Physiol 1985;249:H309-H320.
7. 7. Hescheler J, Kameyama M, Trautwein W: On the mechanism of muscarinic inhibition of the cardiac Ca current. Pflugers Arch 1986;407:182-189.
8. 8. Han X, Shimoni Y, Giles WR: A cellular mechanism for nitric oxide-mediated cholinergic control of mammalian heart rate. J Gen Physiol 1995;106:45-65.
9. 9. Warner MR, Levy MN: Ncuropeptide Y as a putative modulator of the vagal effects on heart rate. Circ Res 1989;64:882-889.
10. 10. Warner MR, Levy MN: Inhibition of cardiac vagal effects by neurally released and exogenous neuropeptide Y. Circ Res 1989;65:1536-1546.
11. 11. Boineau JP, Schuessler RB, Mooney CR, et al: Multicentric origin of the atrial depolarization wave in the pacemaker complex. Circulation 1978;58:1036-1048.
12. 12. Boineau JP, Schuessler RB, Hackel DB, et al: Widespread distribution and rate differentiation of the atrial pacemaker complex. Am J Physiol 1980;239:H406-H415.
13. 13. Randall WC, Jones SB, Lipsius SL, et al: Subsidiary atrial pacemaker and their neural control. In Randall WC, ed. Nervous Control of Cardiovascular Function. Oxford University Press, New York, 1984, p. 199.
14. 14. Schuessler RB, Boineau JP, Wylds AC, et al: Effect of canine cardiac nerves on heart rate, rhythm, and pacemaker location. Am J Physiol 1986;250:H630-H644.
15. 15. Schuessler RB, Boineau JP, Bromberg BI: Origin of the sinus node. J Cardiovasc Electrophysiol 1996;7:263-274.
16. 16. Ardell JL, Randall WC, Pomeroy G, et al: Autonomic regulation of subsidiary atrial pacemakers during exercise. J Appl Physiol 1991;70:1175-1183.
17. 17. Levy MN, Ng ML, Zieske H: Functional distribution of the peripheral cardiac sympathetic pathways. Circ Res 1966;19:650-661.
18. 18. Misaki T, Tsubota M, Watanabe G, et al: Surgical treatment of ventricular tachycardia after surgical repair of tetralogy of Fallot. Relation between intraoperative mapping and histological findings. Circulation 1994;90: 264-271.
19. 19. Hoffman BF, Cranefield PF: The sinoatrial node. In: Electrophysiology of the Heart. Futura Publishing Company, Mount Kisco, New York, 1960, p. 104.
20. 20. Sano T, Yamagishi S: Spread of excitation from the sinus node. Circ Res 1965;16:423-430.
21. 21. Strauss HC, Bigger JT Jr: Electrophysiological properties of the rabbit sinoatrial perinodal fibers. Circ Res 1972;31:490-506.
22. 22. Bromberg BT, Hand DE, Schuessler RB, et al: Primary negativity does not predict dominant pacemaker location: implications for sinoatrial conduction. Am J Physiol 1995;269:H877-H887.
23. 23. Watanabe H, Perry J-B, Page P, et al: Vagal effects on sinoatrial and atrial conduction studied with epicardial mapping in dogs: The influence of pacemaker shifts on the measurement of sinoatrial conduction time. Can J Physiol Pharmacol 1985;63:113-121.
24. 24. Rozanski GJ, Lipsius SL, Randall WC: Functional characteristics of sinoatrial and subsidiary pacemaker activity in the canine right atrium. Circulation 1983;67: 1378-1387.
25. 25. Beau SL, Hand DE, Schuessler RB, et al: Relative densities of muscarinic cholinergic and β-adrenergic receptors in the canine sinoatrial node and their relation to sites of pacemaker activity. Circ Res 1995;77:957-963.
26. 26. Rubenstein DS, Fox LM, McNulty JA, et al: Electrophysiology and ultrastructure of Eustachian ridge from cat right atrium: a comparison with SA node. J Mol Cell Cardiol 1987;19:965-976.
27. 27. Kodama I, Boyett MR: Regional differences in the electrical activity of the rabbit sinus node. Pflugers Arch 1985;404:214-226.