-
1
-
-
15444352201
-
Relevance of age on survival of 341 patients with multiple myeloma treated with conventional chemotherapy: Updated results of the MM87 prospective randomized protocol
-
Cooperative Group of Study and Treatment of Multiple Myeloma
-
RICCARDI A, MORA O, BRUGNATELLI S, et al. Relevance of age on survival of 341 patients with multiple myeloma treated with conventional chemotherapy: updated results of the MM87 prospective randomized protocol. Cooperative Group of Study and Treatment of Multiple Myeloma. Br J Cancer 1998;77:485-491.
-
(1998)
Br J Cancer
, vol.77
, pp. 485-491
-
-
Riccardi, A.1
Mora, O.2
Brugnatelli, S.3
-
3
-
-
0026100542
-
Clinical pharmacokinetics of cyclophosphamide
-
MOORE MJ. Clinical pharmacokinetics of cyclophosphamide. Clin Pharmacokinet 1991;20:194-208.
-
(1991)
Clin Pharmacokinet
, vol.20
, pp. 194-208
-
-
Moore, M.J.1
-
4
-
-
0026748897
-
Cyclophosphamide pharmacokinetics: Correlation with cardiac toxicity and tumor response
-
AYASH LJ, WRIGHT JE, TREIYAKOV O, et al. Cyclophosphamide pharmacokinetics: correlation with cardiac toxicity and tumor response. J Clin Oncol 1992;10:995-1000.
-
(1992)
J Clin Oncol
, vol.10
, pp. 995-1000
-
-
Ayash, L.J.1
Wright, J.E.2
Treiyakov, O.3
-
5
-
-
0018934513
-
Bladder cancer following administration of cyclophosphamide
-
DURKEE C, BENSON R, Jr. Bladder cancer following administration of cyclophosphamide. Urology 1980;16:145-148.
-
(1980)
Urology
, vol.16
, pp. 145-148
-
-
Durkee, C.1
Benson R., Jr.2
-
6
-
-
0020070463
-
Conversion of 4-hydroperoxycyclophosphamide and 4-hydroxycyclophosphamide to phosphoramide mustard and acrolein mediated by bifunctional catalysis
-
LOW JE, BORCH RF, SLADEK NE. Conversion of 4-hydroperoxycyclophosphamide and 4-hydroxycyclophosphamide to phosphoramide mustard and acrolein mediated by bifunctional catalysis. Cancer Res 1982;42:830-837.
-
(1982)
Cancer Res
, vol.42
, pp. 830-837
-
-
Low, J.E.1
Borch, R.F.2
Sladek, N.E.3
-
8
-
-
0029863162
-
Conditioning regimen-dependent disposition of cyclophosphamide and hydroxycyclophosphamide in human marrow transplantation patients
-
SLATTERY JT, KALHORN TF, MCDONALD GB, et al. Conditioning regimen-dependent disposition of cyclophosphamide and hydroxycyclophosphamide in human marrow transplantation patients. J Clin Oncol 1996;14:1484-1494.
-
(1996)
J Clin Oncol
, vol.14
, pp. 1484-1494
-
-
Slattery, J.T.1
Kalhorn, T.F.2
McDonald, G.B.3
-
9
-
-
0029958848
-
Lack of relationship between systemic exposure for the component drug of the fluorouracil, epirubicin, and 4-hydroxycyclophosphamide regimen in breast cancer patients
-
SANDSTROM M, FREUS A, LARSSON R, et al. Lack of relationship between systemic exposure for the component drug of the fluorouracil, epirubicin, and 4-hydroxycyclophosphamide regimen in breast cancer patients. J Clin Oncol 1996;14:1581-1588.
-
(1996)
J Clin Oncol
, vol.14
, pp. 1581-1588
-
-
Sandstrom, M.1
Freus, A.2
Larsson, R.3
-
10
-
-
0023262622
-
Plasma pharmacokinetics of cyclophosphamide and its cytotoxic metabolites after intravenous vs. oral administration in a randomized, crossover trial
-
STRUCK RF, ALBERTS DS, HORNE K, PHILLIPS JG, PENG YM, ROE DJ. Plasma pharmacokinetics of cyclophosphamide and its cytotoxic metabolites after intravenous vs. oral administration in a randomized, crossover trial. Cancer Res 1987;47:2723-2726.
-
(1987)
Cancer Res
, vol.47
, pp. 2723-2726
-
-
Struck, R.F.1
Alberts, D.S.2
Horne, K.3
Phillips, J.G.4
Peng, Y.M.5
Roe, D.J.6
-
11
-
-
0027369366
-
Differential activation of cyclophosphamide and ifosphamide by cytochromes P-450 2B and 3A in human liver microsomes
-
CHANG TK, WEBER GF, CRESPI CL, WAXMAN DJ. Differential activation of cyclophosphamide and ifosphamide by cytochromes P-450 2B and 3A in human liver microsomes. Cancer Res 1993;53:5629-5637.
-
(1993)
Cancer Res
, vol.53
, pp. 5629-5637
-
-
Chang, T.K.1
Weber, G.F.2
Crespi, C.L.3
Waxman, D.J.4
-
12
-
-
0024230301
-
Rapid development of enhanced clearance after high-dose cyclophosphamide
-
MOORE MJ, HARDY RW, THIESSEN JJ, SOLDIN SJ, ERLICHMAN C. Rapid development of enhanced clearance after high-dose cyclophosphamide. Clin Pharmacol Ther 1988;44:622-628.
-
(1988)
Clin Pharmacol Ther
, vol.44
, pp. 622-628
-
-
Moore, M.J.1
Hardy, R.W.2
Thiessen, J.J.3
Soldin, S.J.4
Erlichman, C.5
-
13
-
-
0023638209
-
Repeated high-dose cyclophosphamide administration in bone marrow transplantation: Exposure to activated metabolites
-
SCHULER U, EHNINGER G, WAGNER T. Repeated high-dose cyclophosphamide administration in bone marrow transplantation: exposure to activated metabolites. Cancer Chemother Pharmacol 1987;20:248-252.
-
(1987)
Cancer Chemother Pharmacol
, vol.20
, pp. 248-252
-
-
Schuler, U.1
Ehninger, G.2
Wagner, T.3
-
14
-
-
0028890757
-
Cyclophosphamide metabolism in children
-
YULE SM, BODDY AV, COLE M, et al. Cyclophosphamide metabolism in children. Cancer Res 1995;55:803-809.
-
(1995)
Cancer Res
, vol.55
, pp. 803-809
-
-
Yule, S.M.1
Boddy, A.V.2
Cole, M.3
-
15
-
-
0021747656
-
Positive interactions between interferon and chemotherapy due to direct tumor action rather than effects on host drugmetabolizing enzymes
-
BALKWILL FR, MOWSHOWITZ S, SEILMAN SS, et al. Positive interactions between interferon and chemotherapy due to direct tumor action rather than effects on host drugmetabolizing enzymes. Cancer Res 1984;44:5249-5255.
-
(1984)
Cancer Res
, vol.44
, pp. 5249-5255
-
-
Balkwill, F.R.1
Mowshowitz, S.2
Seilman, S.S.3
-
16
-
-
0023096792
-
Interferons in the treatment of multiple myeloma
-
COOPER MR, WELANDER CE. Interferons in the treatment of multiple myeloma. Cancer 1987;59(Suppl):594-600.
-
(1987)
Cancer
, vol.59
, Issue.SUPPL.
, pp. 594-600
-
-
Cooper, M.R.1
Welander, C.E.2
-
17
-
-
0029834512
-
Cytokine therapy in multiple myeloma
-
PEEST D, BLADE J, HAROUSSEAU JI, KLEIN B, OSTERBORG A, SAN MIGUEL JF. Cytokine therapy in multiple myeloma. Br J Haematol 1996;94:425-432.
-
(1996)
Br J Haematol
, vol.94
, pp. 425-432
-
-
Peest, D.1
Blade, J.2
Harousseau, J.I.3
Klein, B.4
Osterborg, A.5
San Miguel, J.F.6
-
18
-
-
0029005703
-
Interferon-alpha for induction and maintenance in multiple myeloma: Results of two multicenter randomized trials and summary of other studies
-
LUDWIG H, COHEN AM, POLLIACK A, et al. Interferon-alpha for induction and maintenance in multiple myeloma: results of two multicenter randomized trials and summary of other studies. Ann Oncol 1995;6:467-476.
-
(1995)
Ann Oncol
, vol.6
, pp. 467-476
-
-
Ludwig, H.1
Cohen, A.M.2
Polliack, A.3
-
19
-
-
0022982158
-
Interferon alfa-2b-cyclophosphamide combination studies: In vitro and phase I-II clinical results
-
DURIF BG, CLOUSE L, BRAICH T, GRIMM M, ROBERTONE AB. Interferon alfa-2b-cyclophosphamide combination studies: in vitro and phase I-II clinical results. Semin Oncol 1986;13(Suppl 2):84-88.
-
(1986)
Semin Oncol
, vol.13
, Issue.SUPPL. 2
, pp. 84-88
-
-
Durif, B.G.1
Clouse, L.2
Braich, T.3
Grimm, M.4
Robertone, A.B.5
-
20
-
-
0016804136
-
A clinical staging system for multiple myeloma. Correlation of measured myeloma cell mass with presenting clinical features, response to treatment, and survival
-
DURIE BG, SALMON SE. A clinical staging system for multiple myeloma. Correlation of measured myeloma cell mass with presenting clinical features, response to treatment, and survival. Cancer 1975;36:842-854.
-
(1975)
Cancer
, vol.36
, pp. 842-854
-
-
Durie, B.G.1
Salmon, S.E.2
-
21
-
-
0021187214
-
High-performance liquid chromatographic measurement of cyclophosphamide in serum
-
HARDY RW, ERLICHMAN C, SOLDIN SJ. High-performance liquid chromatographic measurement of cyclophosphamide in serum. Ther Drug Monit 1984;6:313-318.
-
(1984)
Ther Drug Monit
, vol.6
, pp. 313-318
-
-
Hardy, R.W.1
Erlichman, C.2
Soldin, S.J.3
-
22
-
-
0028170927
-
Determination of 4-hydroxycyclophosphamide in plasma, us 2,4- dinitrophenylhydrazone derivative of aldophosphamide, by liquid chromatography
-
JOHANSSON M, BIELENSTEIN M. Determination of 4-hydroxycyclophosphamide in plasma, us 2,4- dinitrophenylhydrazone derivative of aldophosphamide, by liquid chromatography. J Chromatogr B Biomed Appl 1994;660:111-120.
-
(1994)
J Chromatogr B Biomed Appl
, vol.660
, pp. 111-120
-
-
Johansson, M.1
Bielenstein, M.2
-
23
-
-
0027394227
-
Natural interferon-alpha in combination with melphalan/prednisone vs. melphalan/prednisone in the treatment of multiple myeloma stages II and III: A randomized study from the Myeloma Group of Central Sweden
-
OSTERBORG A, BJORKHOLM M, BJOREMAN M, et al. Natural interferon-alpha in combination with melphalan/prednisone vs. melphalan/prednisone in the treatment of multiple myeloma stages II and III: a randomized study from the Myeloma Group of Central Sweden. Blood 1993;81:1428-1434.
-
(1993)
Blood
, vol.81
, pp. 1428-1434
-
-
Osterborg, A.1
Bjorkholm, M.2
Bjoreman, M.3
-
24
-
-
0027447339
-
A randomized clinical trial comparing melphalan/prednisone with or without interferon alfa-2b in newly diagnosed patients with multiple myeloma: A cancer and leukemia group B study
-
COOPER MR, DEAR K, MCINTYRE OR, et al. A randomized clinical trial comparing melphalan/prednisone with or without interferon alfa-2b in newly diagnosed patients with multiple myeloma: a Cancer and Leukemia Group B study. J Clin Oncol 1993;11:155-160.
-
(1993)
J Clin Oncol
, vol.11
, pp. 155-160
-
-
Cooper, M.R.1
Dear, K.2
McIntyre, O.R.3
-
25
-
-
0021167354
-
Plasma concentrations of 4-hydroxycyclophosphamide and phosphoramide mustard in patients repeatedly given high doses of cyclophosphamide in preparation for bone marrow transplantation
-
SLADEK NE, DOEDEN D, POWERS JF, KRIVET W. Plasma concentrations of 4-hydroxycyclophosphamide and phosphoramide mustard in patients repeatedly given high doses of cyclophosphamide in preparation for bone marrow transplantation. Cancer Treat Rep 1984;68:1247-1254.
-
(1984)
Cancer Treat Rep
, vol.68
, pp. 1247-1254
-
-
Sladek, N.E.1
Doeden, D.2
Powers, J.F.3
Krivet, W.4
-
26
-
-
0026026522
-
Pharmacokinetics of 4-hydroxycyclophosphamide and metabolites in the rat
-
HONG PS, SRIGRITSANAPOL A, CHAN KK. Pharmacokinetics of 4-hydroxycyclophosphamide and metabolites in the rat. Drug Metab Dispos 1991;19:1-7.
-
(1991)
Drug Metab Dispos
, vol.19
, pp. 1-7
-
-
Hong, P.S.1
Srigritsanapol, A.2
Chan, K.K.3
-
27
-
-
0030916085
-
Nonlinear pharmacokinetics of cyclophosphamide and 4-hydroxycyclophosphamide/aldophosphamide in patients with metastatic breast cancer receiving high-dose chemotherapy followed by autologous bone marrow transplantation
-
CHEN TL, KENNEDY MJ, ANDERSON LW, et al. Nonlinear pharmacokinetics of cyclophosphamide and 4-hydroxycyclophosphamide/aldophosphamide in patients with metastatic breast cancer receiving high-dose chemotherapy followed by autologous bone marrow transplantation. Drug Metab Dispos 1997;25:544-551.
-
(1997)
Drug Metab Dispos
, vol.25
, pp. 544-551
-
-
Chen, T.L.1
Kennedy, M.J.2
Anderson, L.W.3
-
28
-
-
0030951908
-
Enhanced cyclophosphamide and ifosfamide activation in primary human hepatocyte cultures: Response to cytochrome P-450 inducers and autoinduction by oxazaphosphorines
-
CHANG TK, YU L, MAUREL P, WAXMAN DJ. Enhanced cyclophosphamide and ifosfamide activation in primary human hepatocyte cultures: response to cytochrome P-450 inducers and autoinduction by oxazaphosphorines. Cancer Res 1997;57:1946-1954.
-
(1997)
Cancer Res
, vol.57
, pp. 1946-1954
-
-
Chang, T.K.1
Yu, L.2
Maurel, P.3
Waxman, D.J.4
-
29
-
-
0027284901
-
Modulation of rat hepatic CYP3A1 induction by the interferon inducer polyinosinic acid-polycytidylic acid (polyic)
-
DELAPORTE E, CRIBB AE, RENTON KE. Modulation of rat hepatic CYP3A1 induction by the interferon inducer polyinosinic acid-polycytidylic acid (polyic). Drug Metab Dispos 1993;21:520-523.
-
(1993)
Drug Metab Dispos
, vol.21
, pp. 520-523
-
-
Delaporte, E.1
Cribb, A.E.2
Renton, K.E.3
-
30
-
-
0029022894
-
The duration of induction and species influences the downregulation of cytochrome P450 by the interferon inducer polyinosinic acid- polycytidylic acid
-
ANARI MR, CRIBB AE, RENTON KW. The duration of induction and species influences the downregulation of cytochrome P450 by the interferon inducer polyinosinic acid- polycytidylic acid. Drug Metab Dispos 1995;23:536-541.
-
(1995)
Drug Metab Dispos
, vol.23
, pp. 536-541
-
-
Anari, M.R.1
Cribb, A.E.2
Renton, K.W.3
-
34
-
-
0026448886
-
Individual variation in the activation and inactivation of metabolic pathways of cyclophosphamide
-
[see comments]
-
BODDY AV, FURTUN Y, SARDAS S, SARDAS O, IDLE JR. Individual variation in the activation and inactivation of metabolic pathways of cyclophosphamide [see comments]. J Natl Cancer Inst 1992;84:1744-1748.
-
(1992)
J Natl Cancer Inst
, vol.84
, pp. 1744-1748
-
-
Boddy, A.V.1
Furtun, Y.2
Sardas, S.3
Sardas, O.4
Idle, J.R.5
-
35
-
-
0023814716
-
Phenotypically deficient urinary, elimination of carboxyphosphamide after cyclophosphamide administration to cancer patients
-
HADIDI AH, COULTER CE, IDLE JR. Phenotypically deficient urinary, elimination of carboxyphosphamide after cyclophosphamide administration to cancer patients. Cancer Res 1988;48:5167-5171.
-
(1988)
Cancer Res
, vol.48
, pp. 5167-5171
-
-
Hadidi, A.H.1
Coulter, C.E.2
Idle, J.R.3
-
36
-
-
0026907527
-
Molecular genetics of human aldehyde dehydrogenase
-
YOSHIDA A. Molecular genetics of human aldehyde dehydrogenase. Pharmacogenetics 1992;2:139-147.
-
(1992)
Pharmacogenetics
, vol.2
, pp. 139-147
-
-
Yoshida, A.1
-
37
-
-
0028336681
-
Hepatic and serologic toxicity of systemic interleukin-2 and/or interferon-alpha. Evidence of a risk-benefit advantage of subcutaneous therapy
-
SCHOMBURG A, KIRCHNER H, LOPEZ-HANNINEN E, et al. Hepatic and serologic toxicity of systemic interleukin-2 and/or interferon-alpha. Evidence of a risk-benefit advantage of subcutaneous therapy. Am J Clin Oncol 1994;17:199-209.
-
(1994)
Am J Clin Oncol
, vol.17
, pp. 199-209
-
-
Schomburg, A.1
Kirchner, H.2
Lopez-Hanninen, E.3
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