Optimization of a vehicle mixture for the transdermal delivery of melatonin using artificial neural networks and response surface method

Journal of Controlled Release

Volumn 61, Issue 1-2, 1999, Pages 71-82

  Kandimalla, Karunya K ^a   Kanikkannan, Narayanasamy ^a   Singh, Mandip ^a  

^a FLORIDA A AND M UNIVERSITY   (United States)

Author keywords

Artificial neural networks; Melatonin; Rat; Response surface method; Transdermal vehicles

Indexed keywords

MELATONIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ARTIFICIAL NEURAL NETWORK; CIRCADIAN RHYTHM; CONTROLLED STUDY; DRUG PENETRATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; JET LAG; METHODOLOGY; NONHUMAN; PRIORITY JOURNAL; RAT; SKIN; SLEEP DISORDER; STRATUM CORNEUM; TRANSDERMAL DRUG ADMINISTRATION;

ADMINISTRATION, CUTANEOUS; ANIMALS; MELATONIN; NEURAL NETWORKS (COMPUTER); PERMEABILITY; RATS; RATS, SPRAGUE-DAWLEY; SOLUBILITY; VEHICLES;

EID: 0032865057     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(99)00107-8     Document Type: Article

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