Secondary leukaemia and myelodysplasia after autografting for lymphoma: Results from the EBMT

British Journal of Haematology

Volumn 106, Issue 4, 1999, Pages 1020-1026

  Milligan, Donald W ^a   De Elvira, M Carmen Ruiz ^b   Kolb, Hans Jochem ^b   Goldstone, Anthony H ^b   Meloni, Giovanna ^b   Rohatiner, Ama Z ^b   Colombat, Phillip ^b   Schmitz, Norbert ^b  

^a BIRMINGHAM HEARTLANDS HOSPITAL   (United Kingdom)

^b NONE

Author keywords

Autografting; Leukaemia; Lymphoma; Myelodysplasia; Stem cell

Indexed keywords

ADOLESCENT; ADULT; ARTICLE; AUTOLOGOUS BONE MARROW TRANSPLANTATION; CANCER RISK; CHILD; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; HODGKIN DISEASE; HUMAN; LEUKEMIA; MAJOR CLINICAL STUDY; MALE; MYELODYSPLASIA; NONHODGKIN LYMPHOMA; PRIORITY JOURNAL; RISK ASSESSMENT; RISK FACTOR; SCHOOL CHILD; SECOND CANCER; SEX DIFFERENCE;

ADOLESCENT; ADULT; BONE MARROW TRANSPLANTATION; CHILD; EUROPE; FEMALE; HUMANS; LEUKEMIA; LEUKEMIA, MYELOID; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; MYELODYSPLASTIC SYNDROMES; RECURRENCE; RISK FACTORS; SURVIVAL ANALYSIS; TRANSPLANTATION, AUTOLOGOUS;

EID: 0032863660     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.1999.01627.x     Document Type: Article

References (24)

1. André, M., Henry-Amar, M., Blaise, D., Colombat, P., Fleury, J., Milpied, N., Cahn, J.-Y., Pico, J.-L., Bastion, Y., Kuentz, M., Nedellec, J., Attal, M., Fermé, C. & Gissellbrecht, C. (1998) Treatment-related deaths and second cancer risks after autologous stem-cell transplantation for Hodgkin's disease. Blood, 92, 1933-1940.
2. Armitage, J.O. (1994) Bone marrow transplantation. New England Journal of Medicine, 330, 827-838.
3. Bhatia, S., Ramsay, N.K., Steinbuch, M., Dusenbery, K.E., Shapiro, R.S., Weisdorf, D.J., Robinson, L.L., Miller, J.S. & Neglia, J.P. (1996) Malignant neoplasms following bone marrow transplantation. Blood, 87, 3633-3639.
4. Darrington, D.L., Vose, J.M., Anderson, J.R., Bierman, P.J., Bishop, M.R., Chan, W.C., Morris, M.E., Reede, E.C., Sanger, W.G. & Tarantolo, S.R. (1994) Incidence and characterisation of secondary myelodysplastic syndrome and acute myelogenous leukemia following high-dose chemo-radiotherapy and autologous stem-cell transplantation for lymphoid malignancies. Journal of Clinical Oncology. 12, 2527-2534.
5. Govindarajan, R., Jagannath, S., Flick, J.T., Vesole, D.H., Sawyer, J., Barlogie, B. & Tricot, G. (1996) Preceding standard therapy is the likely cause of MDS after autotransplants for multiple myeloma. British Journal of Haematology. 95, 349-353.
6. Greene, M.H., Young, R.C., Merrill, J.M. & De Vita, V.T. (1983) Evidence of a treatment dose response in acute nonlymphocytic leukaemias which occur after therapy of non-Hodgkin's lymphoma. Cancer Research, 43, 1891-1898.
7. Hess, C.F., Kortman, R.D., Schmidbergar, H. & Bamberg, M. (1994) How relevant is secondary leukaemia for initial treatment selection in Hodgkin's disease? European Journal of Cancer, 30A, 1441-1447.
8. Jackson, G.H., Latham, J., Lennard, A., Taylor, F. & Proctor, S. (1995) Rapid onset of chronic granulocytic leukaemia after treatment for Hodgkin's disease. British Journal of Haematology. 87, 193-195.
9. Kaldor, J.M., Day, N.E., Clarke, A., Van Leeuwen, F.E., Henry-Amar, M., Fiorentino, M., Bell J., Band, P. & Assouline, D. (1990) Leukemia following Hodgkin's disease. New England Journal of Medicine, 322, 7-13.
10. Kumar, I., (1993) Secondary leukaemia after autologous bone marrow transplantation. Lancet, 345, 810.
11. Miller, J.S., Arthur, D.C., Litz, C.E., Neglia, J.P., Miller, W.J. & Weisdorf, J.F. (1994) Myelodysplastic syndrome after autologous bone marrow transplantation: an additional late complication of curative cancer therapy. Blood, 83, 3988-3989.
12. Pedersen-Bjergard, J., Ersboll, J., Sorensen, H.M., Keiding, M., Larsen, S.O., Philip, P., Larsen, M.S., Schultz, H. & Nissen, N.I. (1985) Risk of acute non lymphocytic leukemia and pre leukemia in patients treated with cyclophosphamide for non-Hodgkin's lymphoma: comparison with results obtained in patients treated for Hodgkin's disease and ovarian carcinoma with other alkylating agents. Annals of Internal Medicine, 103, 195-200.
13. Pedersen-Bjergaard, J. & Larsen, S.O. (1982) Incidence of acute non lymphocytic leukemia, pre-leukemia and acute myeloproliferative syndromes up to 10 years after treatment of Hodgkin's disease. New England Journal of Medicine. 307, 965-971.
14. Pedersen-Bjergaard, J., Pedersen, M., Myhre, J. & Geisler, C. (1997) High risk of therapy-related leukemia after BEAM chemotherapy and autologous stem-cell transplantation for previously treated lymphomas is mainly related to primary chemotherapy and not to the BEAM transplantation procedure. Leukemia, 11, 1654-1660.
15. Pedersen-Bjergaard, J., Specht, L., Larsen, S.O., Ersboll, J., Struck, J., Hansen, M.M. & Nissen, N.I. (1987) Risk of therapy-related leukaemia and preleukaemia after Hodgkin's disease. Lancet, ii, 83-88.
16. Peniket, A.J., Taghipour, G., Milligan, D.W., Blystad, M. & Goldstone, A.H. (1997) BEAM is a better conditioning regimen than cyclophosphamide/TBI for adults with lymphoblastic lymphoma undergoing autologous transplantation: a retrospective matched-pair analysis from the EBMT Registry. Bone Marrow Transplantation, 19, (Suppl. 1), 573.
17. Rohatiner, A. (1994) Myelodysplasia and acute myelogenous leukemia after myeloablative therapy with autologous stem-cell transplantation. Journal of Clinical Oncology, 12, 2521-2523.
18. Roy, D.C., Tantravahi, R., Murray, C., Dear, K., Gorgone, B., Anderson, K.C., Freedman, A.S., Nadler, L.M. & Ritz, J. (1990) Natural history of mixed chimerism after bone marrow transplantation with CD6-depleted allogeneic marrow: a stable equilibrium. Blood. 75, 296-304.
19. Stone, R.M. (1994) Myelodysplastic syndrome after autologous transplantation for lymphoma: the price of progress. Blood, 83, 3437-3440.
20. Stone, R.M., Neuberg, D., Soiffer, R., Takvorian, T., Whelan, M., Rabinowe, S.N., Aster, J.C., Leavitt, H, Mauch, P. & Freedman, A.S. (1994) Myelodysplastic syndrome as a late complication following autologous bone marrow transplantation for non-Hodgkin's lymphoma. Journal of Clinical Oncology, 12, 2535-2542.
21. Swerdlow, A.J., Douglas, A.J., Vaughan-Hudson, G., Vaughan-Hudson, B. & MacLennan, K.A. (1993) Risk of second primary cancer after Hodgkin's disease in patients in the British National Lymphoma Investigation: relationship to host factors, histology and stage of Hodgkin's disease, and splenectomy. British Journal of Cancer, 68, 1006-1011.
22. Taylor, P.R.A., Jackson, G.H., Lennard, A.L., Hamilton. P.J. & Proctor, S.J. (1997) Low incidence of myelodysplastic syndrome following transplantation using autologous non-cryopreserved bone marrow. Leukemia. 11, 1650-1653.
23. Travis, L.B., Weeks, J., Curtis, R.E., Chaffey, J.T., Stovall, M., Banks, P.M. & Boice, J.D. (1996) Leukemia following low-dose total body irradiation and chemotherapy for non-Hodgkin's lymphoma. Journal of Clinical Oncology. 14, 565-571.
24. Traweek, S.T., Slovak, M.C., Nadamence, A.P., Brynes, R.K., Niland, J.C. & Forman, S.J. (1994) Clonal karyotypic hemopoietic cell abnormalities occurring after autologous bone marrow transplantation for Hodgkin's disease and non-Hodgkin's lymphoma. Blood, 84, 957-963.