Determination of drug-plasma protein binding using human serum albumin chromatographic column and multiple linear regression model

Biomedical Chromatography

Volumn 13, Issue 6, 1999, Pages 401-406

  Beaudry, Francis ^a   Coutu, Michel ^a   Brown, Nigel K ^a  

^a MDS Inc   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; BIOCHEMISTRY; BODY FLUIDS; CHROMATOGRAPHY; PROTEINS;

CALIBRATION CURVES; CHROMATOGRAPHIC COLUMN; HUMAN SERUM ALBUMINS; MULTIPLE LINEAR REGRESSION MODELS; PHARMACEUTICAL COMPOUNDS; PHARMACOKINETICS AND PHARMACODYNAMICS; PLASMA PROTEIN BINDING; PROTEIN-BINDING; SERUM PROTEINS; THERAPEUTIC AGENTS;

MULTIPLE LINEAR REGRESSION;

ACICLOVIR; ALPRAZOLAM; AMANTADINE; AMFEBUTAMONE; BECLOMETASONE; BETAMETHASONE; BROMAZEPAM; BUDESONIDE; CARBAMAZEPINE; CHLORPHENIRAMINE; CLONAZEPAM; CLONIDINE; DESIPRAMINE; DILTIAZEM; DIPHENHYDRAMINE; DOXEPIN; FAMOTIDINE; GABAPENTIN; GANCICLOVIR; HUMAN SERUM ALBUMIN; IMIPRAMINE; INDAPAMIDE; LORAZEPAM; LORMETAZEPAM; NITRAZEPAM; NIZATIDINE; PLASMA PROTEIN; RANITIDINE; UNINDEXED DRUG; ZIDOVUDINE;

ARTICLE; BINDING AFFINITY; COLUMN CHROMATOGRAPHY; CORRELATION FUNCTION; DRUG PROTEIN BINDING; PLASMA PROTEIN BINDING; PROTEIN IMMOBILIZATION; PUMP; SAMPLER; STATISTICAL MODEL;

EID: 0032862638     PISSN: 02693879     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-0801(199910)13:6<401::AID-BMC899>3.0.CO;2-C     Document Type: Article

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