An in vitro investigation into the potential for bimodal drug release from pectin/chitosan/HPMC-coated tablets

International Journal of Pharmaceutics

Volumn 188, Issue 1, 1999, Pages 11-18

  MacLeod, Graeme S ^a   Fell, John T ^a   Collett, John H ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Bimodal delivery; Chitosan; Coating; Disintegrants; Pectin

Indexed keywords

CALCIUM PHOSPHATE DIBASIC; CELLULOSE; CHITOSAN; CITRIC ACID TRIETHYL ESTER; COPOLYMER; CROSCARMELLOSE SODIUM; DISINTEGRATING AGENT; EUDRAGIT; GLYCEROL; GLYCEROL STEARATE; HYDROXYPROPYLMETHYLCELLULOSE; MAGNESIUM STEARATE; METHYLCELLULOSE; MICROCRYSTALLINE CELLULOSE; PARACETAMOL; PECTIN; POLYMETHACRYLIC ACID DERIVATIVE; POLYSORBATE 80; POVIDONE; STARCH; STARCH GLYCOLATE SODIUM;

ARTICLE; DRUG RELEASE; IN VITRO STUDY; MODEL; PH; PRIORITY JOURNAL; TABLET; WATER TRANSPORT;

ACETAMINOPHEN; ANALGESICS, NON-NARCOTIC; CHITIN; CHITOSAN; DELAYED-ACTION PREPARATIONS; DRUG COMPOUNDING; HYDROGEN-ION CONCENTRATION; KINETICS; LACTOSE; METHYLCELLULOSE; OXAZINES; PECTINS; TABLETS; TABLETS, ENTERIC-COATED; TIME FACTORS; WATER;

EID: 0032862025     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(99)00197-0     Document Type: Article

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