Fetal partial urethral obstruction causes renal fibrosis and is associated with proteolytic imbalance

Journal of Urology

Volumn 162, Issue 3 I, 1999, Pages 854-860

  Gobet, Rita ^a   Bleakley, Jeffrey ^a   Cisek, Lars ^a   Kaefer, Martin ^a   Moses, Marsha A ^a   Fernandez, Cecilia A ^a   Peters, Craig A ^a  

^a NONE

Author keywords

Fibrosis; Kidney; Metalloproteinases; Urethral obstruction

Indexed keywords

ACETYLGLUCOSAMINIDASE; ALPHA ACTIN; COLLAGEN; DNA; ELECTROLYTE; METALLOPROTEINASE; PROTEIN; TISSUE INHIBITOR OF METALLOPROTEINASE;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONNECTIVE TISSUE; CONTROLLED STUDY; DISEASE ASSOCIATION; ENZYME ACTIVITY; FETUS; IMMUNOHISTOCHEMISTRY; KIDNEY FIBROSIS; MORPHOMETRICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; SHEEP; URETHRA STENOSIS; URINE;

EID: 0032861918     PISSN: 00225347     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005392-199909010-00077     Document Type: Article

References (29)

1. Dinneen, M. D. and Duffy, P. G.: Posterior urethral valves. Brit. J. Urol., 78: 275, 1996.
2. Minoja, M., Hischman, G., Jones, C., Agodoa, L. and Striker, G.: Incidence and causes of ESRD in children in the USA. J. Amer. Soc. Nephrol., 6: 396, abstract 875, 1995.
3. Pieretti, R. V.: The mild end of the clinical spectrum of posterior urethral valves. J. Fed. Surg., 28: 701, 1993.
4. Peters, C. A., Freeman, M. R., Fernandez, C. A., Shepard, J., Wiederschain, D. G. and Moses, M. A.: Dysregulated proteolytic balance as the basis of extracellular matrix in fibrotic disease. Amer. J. Physiol., 272: R1960, 1997.
5. Eddy, A. A. and Giachelli, C. M.: Renal expression of genes that promote interstitial inflammation and fibrosis in rats with protein-overload proteinuria. Kidney Int., 47: 1546, 1995.
6. Engelmeyer, E., van Goor, H., Edwards, D. R. and Diamond, J. R.: Differential mRNA expression of renal cortical tissue inhibitor of metalloproteinase-1, -2, and -3 in experimental hydronephrosis. J. Amer. Soc. Nephrol., 5: 1675, 1995.
7. Goumenos, D. S., Brown, C. B., Shortland, J. and el Nahas, A. M.: Myofibroblasts, predictors of progression of mesangial IgA nephropathy? Nephrol. Dial. Transplant., 9: 1418, 1994.
8. Zhang, G., Moorhead, P. J. and el Nahas, A. M.: Myofibroblasts and the progression of experimental glomerulonephritis. Exp. Nephrol., 3: 308, 1995.
9. Peters, C. A., Docimo, S. G., Luetic, T., Reid, L. M., Retik, A. B. and Mandell, J.: Effect of in utero vesicostomy on pulmonary hypoplasia in the fetal lamb with bladder outlet obstruction and oligohydramnios: a morphometric analysis. J. Urol., 146: 1178, 1991.
10. Giles, K. W. and Myers, A.: An improved diphenylamine method for the estimation of deoxyribonucleic acid. Nature, 206: 680, 1965.
11. Bergmann, I. and Loxley, R.: Two improved and simplified methods for the spectrophotometric determination of hydroxyproline. Anal. Chem., 35: 1961, 1963.
12. Herron, G. S., Banda, M. J., Clark, E. J., Gavrilovic, J. and Werb, Z.: Secretion of metalloproteinases by stimulated capillary endothelial cells. II. Expression of collagenase and stromelysin activities is regulated by endogenous inhibitors. J. Biol. Chem., 261: 2814, 1986.
13. Moses, M., Sudhalter, J. and Langer, R.: Identification of an inhibitor of neovascularization from cartilage. Science, 248: 1408, 1990.
14. Marhun, D.: Rapid colorimetric assay of beta-galactosidase and N-acetyl-beta-glucosaminidase in human urine. Clin. Chim. Acta, 73: 453, 1976.
15. Eddy, A. A.: Molecular insights into renal interstitial fibrosis (Editorial). J. Amer. Soc. Nephrol., 7: 2495, 1996.
16. Yu, A. E., Hewitt, R. E., Connor, E. W. and Stetler-Stevenson, W. G.: Matrix metalloproteinasees. Novel targets for directed cancer therapy. Drugs Aging, 11: 229, 1997.
17. Davies, M. J.: Aortic aneurysm formation: lessons from human studies and experimental models (Editorial). Circulation, 98: 193, 1998.
18. Ziegler, J.: Cancer and arthritis share underlying processes (news). J. Natl. Cancer Inst., 90: 802, 1998.
19. Furness, P. N.: Extracellular matrix and the kidney. J. Clin. Path., 49: 355, 1996.
20. Medjebeur, A. A., Bussieres, L., Gasser, B., Gimonet, V. and Laborde, K.: Experimental bilateral urinary tract obstruction in fetal sheep: transforming growth factor-beta 1 expression. Amer. J. Physiol., 273: F372, 1997.
21. Gobet, R., Park, J. M., Chang, B., Cisek, L. J. and Peters, C. A.: Partial bladder outlet obstruction causes changes in gene expression of the renal renin/angiotensin system in fetal sheep. J. Amer. Soc. Nephrol., 9: 494A, abstract 2524, 1998.
22. Hirakata, M., Kaname, S., Chung, U. G., Joki, N., Hori, Y., Noda, M., Takuwa, Y., Okazaki, T., Fujita, T., Katoh, T. and Kurokawa, K. : Tyrosine kinase dependent expression of TGF-beta induced by stretch in mesangial cells. Kidney Int., 51: 1028, 1997.
23. Diamond, J. R., van Goor, H., Ding, G. and Engelmyer, E.: Myofibroblasts in experimental hydronephrosis. Amer. J. Path., 146: 121, 1995.
24. Wu, L. L., Yang, N., Roe, C. J., Cooper, M. E., Gilbert, R. E., Atkins, R. C. and Lan, H. Y.: Macrophage and myofibroblast proliferation in remnant kidney: role of angiotensin II. Kidney Int., 63: S221, 1997.
25. Daikha-Dahmane, F., Dommegues, M., Muller, F., Narcy, F., Lacoste, M., Beziau, A., Dumez, Y. and Gubler, M.-C.: Development of human fetal kidney in obstructive uropathy: correlations with ultrasonography and urine biochemistry. Kidney Int., 52: 21, 1997.
26. Attar, R., Quinn, F., Winyard, P. J., Mouriguand, P. D., Foxall, P., Hanson, M. A., and Woolf, A. S.: Short-term urinary flow impairement deregulates PAX2 and PCNA expression and cell survival in fetal sheep kidneys. Amer. J. Path., 152: 1225, 1998.
27. Winyard, P. J. D., Risdon, R. A., Sams, V. R., Dressler, G. R. and Woolf, A. S.: The PAX2 transcription factor is expressed in cystic and hyperproliferative dysplastic epithelia in human kidney malformations. J. Clin. Invest., 98: 451, 1996.
28. Rogers, S. A., Ryan, G., Purchio, A. F. and Hammerman, H. R.: Metanephric transforming growth factor b1 regulates nephrogenesis in vitro. Amer. J. Physiol., part 2, 264: F996, 1993.
29. Huland, H., Gonnermann, D., Werner, B. and Possin, U.: A new test to predict reversibility of hydronephrotic atrophy after stable partial unilateral ureteral obstruction. J. Urol., 140: 1591, 1988.