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Volumn 4, Issue 4, 1999, Pages 187-192

Mechanism-based inhibitors: Development of a high throughput coupled enzyme assay to screen for novel antimalarials

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMALARIAL AGENT; ENZYME INHIBITOR; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; INOSINATE DEHYDROGENASE;

EID: 0032860872     PISSN: 10870571     EISSN: None     Source Type: Journal    
DOI: 10.1177/108705719900400406     Document Type: Article
Times cited : (10)

References (12)
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    • Hypoxanthinc phosphoribosyl transferase and guanine metabolism of adenocarcinoma 755 cells
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    • Hill, D.L.1
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    • Characterization of human Type I and Type II IMP-dehydrogenases
    • Carr, S.F., Papp, E., Wu, J.C., Natsumeda, Y. (1993). Characterization of human Type I and Type II IMP-dehydrogenases. J. Biol. Chem. 268:27286-27290.
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  • 7
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    • Structure and mechanism of inosine monophosphate dehydrogenase in complex with the immunosuppressant mycophenolic acid
    • Sintchak, M.D., Fleming, M.A., Futer, O., Raybuck, S.A., Chambers, S.P., Caron, P.R., Murcko, M.A., Wilson, K.P. (1996). Structure and mechanism of inosine monophosphate dehydrogenase in complex with the immunosuppressant mycophenolic acid. Cell 85:921-930.
    • (1996) Cell , vol.85 , pp. 921-930
    • Sintchak, M.D.1    Fleming, M.A.2    Futer, O.3    Raybuck, S.A.4    Chambers, S.P.5    Caron, P.R.6    Murcko, M.A.7    Wilson, K.P.8
  • 8
    • 0017311840 scopus 로고
    • Human malaria parasites in continuous culture
    • Trager, W., Jensen, J.B. (1976). Human malaria parasites in continuous culture. Science 193:673-675.
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    • Trager, W.1    Jensen, J.B.2
  • 9
    • 0018606732 scopus 로고
    • Quantitative assessment of antimalarial activity in vitro by a semi-automated microdilution technique
    • Desjardins, R.E., Canfield, C.J., Haynes, J.D., Chulay, J.D. (1979). Quantitative assessment of antimalarial activity in vitro by a semi-automated microdilution technique. Antimicrob. Agents. Chemother. 16:710-718.
    • (1979) Antimicrob. Agents. Chemother. , vol.16 , pp. 710-718
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    • Use of radioactive ethanolamine incorporation into phospholipids to assess in vitro antimalarial activity by the semiautomated microdilution technique
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    • Regulation of 5-phosphoribosyl 1-pyrophosphate and of hypoxanthine uptake and release in human erythrocytes by oxypurine cycling
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.