CNS-specific prostacyclin ligands as neuronal survival-promoting factors in the brain

European Journal of Neuroscience

Volumn 11, Issue 9, 1999, Pages 3115-3124

  Satoh, Takumi ^a   Ishikawa, Yasuyuki ^b   Kataoka, Yosky ^a   Cui, Yilong ^c   Yanase, Hisato ^c   Kato, Koichi ^d   Watanabe, Yumiko ^a,e   Nakadate, Kazuhiko ^a   Matsumura, Kiyoshi ^a,e   Hatanaka, Hiroshi ^b   Kataoka, Kiyoshi ^c   Noyori, Ryoji ^d   Suzuki, Masaaki ^e,f   Watanabe, Yasuyoshi ^a,e  

^a OSAKA BIOSCIENCE INSTITUTE   (Japan)

^b BIOMOL ENG RESEARCH INSTITUTE   (Japan)

^c EHIME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d NAGOYA UNIVERSITY   (Japan)

^e JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^f GIFU UNIVERSITY   (Japan)

Author keywords

(15R) 16 m tolyl 17,18,19,20 tetranorisocarbacyclin; Ischaemia; Neuronal death; Prostaglandin; Reactive oxygen species

Indexed keywords

6 OXOPROSTAGLANDIN F1 ALPHA; CARBACYCLIN DERIVATIVE; LIGAND; NERVE GROWTH FACTOR; OXYGEN; PROSTACYCLIN RECEPTOR; PROSTAGLANDIN; RECEPTOR SUBTYPE; XANTHINE; XANTHINE OXIDASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BINDING AFFINITY; BRAIN; BRAIN ISCHEMIA; CELL SURVIVAL; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DEGENERATIVE DISEASE; EMBRYO; GERBIL; HIPPOCAMPUS; NERVE CELL NECROSIS; NEUROPROTECTION; NONHUMAN; PERIPHERAL NERVOUS SYSTEM; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RAT;

ANIMALS; AUTORADIOGRAPHY; BRAIN ISCHEMIA; CELL DEATH; CELL SURVIVAL; CENTRAL NERVOUS SYSTEM; EPOPROSTENOL; FEMALE; GERBILLINAE; HIPPOCAMPUS; HYPEROXIA; LIGANDS; MALE; NEURONS; PYRAMIDAL CELLS; RATS; RATS, WISTAR; RECEPTORS, EPOPROSTENOL; RECEPTORS, PROSTAGLANDIN; XANTHINE; XANTHINE OXIDASE;

EID: 0032860115     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1460-9568.1999.00791.x     Document Type: Article

References (44)

1. 2 protects cultured cortical neurons against N-methyl-D-aspartate receptor-mediated glutamate toxicity. Brain Res., 663, 237-243.
2. Araki, T., Enokido, Y., Inamura, N., Aizawa, S., Reed, J.C. & Hatanaka, H. (1998) Changes in c-Jun but not Bcl-2 family proteins in p53-dependent apoptosis of mouse cerebellar granule neurons induced by DNA damaging agent bleomycin. Brain Res., 794, 239-247.
3. Buchan, A. & Pulsinelli, W.A. (1990) Hypothermic but not the N-methyl-D-aspartate antagonist, MK801, attenuates neuronal damage in gerbils subjected to transient global ischemia. J. Neurosci., 10, 311-316.
4. 2) protects rat cortical neurons in culture against hypoxia/reoxygenation and glutamate-induced injury. Neurosci. Lett., 160, 106-108.
5. Cazevieille, C., Muller, A., Maynier, F., Dutrait, N. & Bonne, C. (1994) Protection by prostaglandins from glutamate toxicity in cortical neurons. Neurochem. Int., 24, 395-398.
6. Deshmukh, M. & Johnson, E.M. Jr (1997) Programmed cell death in neurons: focus on the pathway of nerve growth factor deprivation-induced death of sympathetic neurons. Mol. Pharmacol., 51, 897-906.
7. 2 against the toxic effects of actinomycin C on embryonic neural retina cells. Prostaglandins, 44, 129-134.
8. Enokido, Y. & Hatanaka, H. (1993) Apoptotic cell death occurs in hippocampal neurons cultured in a high oxygen atmosphere. Neuroscience, 57, 965-972.
9. Fischer, M., Meadows, M.-E., Do, T., Weise, J., Trubetskoy, V., Charette, M. & Finklestein, S.P. (1995) Delayed treatment of intravenous basic fibroblast growth factor reduces infarct size following permanent focal cerebral ischemia in rats. J. Cereb. Blood Flow Metab., 15, 953-959.
10. 2+ influx but not Trk activation. J. Neurosci., 15, 643-664.
11. Gaudet, R.J., Alam, I. & Levine, L. (1980) Accumulation of cyclooxygenase products of arachidonic acid metabolism in gerbil brain during reperfusion after bilateral common carotid artery occlusion. J. Neurochem., 35, 653-658.
12. Goehlert, U.G., Ng, Y., Kin, N.M.K. & Wolfe, L.S. (1981) Biosynthesis of prostacyclin in rat cerebral micro vessels and the choroid plexus. J. Neurochem., 36, 1192-1201.
13. Gryglewski, R.J. (1979) Prostacyclin as a circulating hormone. Biochem. Pharmacol., 28, 3161-3166.
14. Ishikawa, Y., Satoh, T., Enokido, Y., Nishio, C. & Hatanaka, H. (1999) Generation of reactive oxygen species, release of L-glutamate and activation of caspase are required the high oxygen-induced apoptosis of embryonic hippocampal neurons in culture. Brain Res., 824, 71-80.
15. Jordan, J., Galindo, M.F. & Miller, R.J. (1997) Role of calpain- and interleukin-1β converting enzyme-like proteases in the β-amyloid-induced death to rat hippocampal neurons in culture. J. Neurochem., 68, 1612-1621.
16. Kirino, T. (1982) Delayed neuronal death in the gerbil hippocampus following ischemia. Brain Res., 239, 57-69.
17. Kubo, T., Enokido, Y., Yamada, M., Oka, T., Uchiyama, Y. & Hatanaka, H. (1996) Oxygen-induced apoptosis in PC12 cells with special reference to the role of Bcl-2. Brain Res., 733, 175-183.
18. Kushima, Y., Tsukui, H., Enokido, Y., Nishio, C. & Hatanaka, H. (1990) High oxygen atmosphere for neuronal cell culture with nerve growth factor. I. Primary culture of basal forebrain cholinergic neurons from fetal and postnatal rats. Brain Res., 536, 16-22.
19. Li, Y., Maher, P. & Schubert, D. (1997) A role of 12-lipoxygenase in nerve cell death caused by glutathione depletion. Neuron, 19, 453-463.
20. 2 analog, TEI-7165, on ischemic neuronal damage in gerbils. Brain Res., 769, 321-328.
21. Matsumura, K., Cao, C., Watanabe, Yu. & Watanabe, Y. (1998) Prostaglandin system in the brain: site of biosynthesis and site of action under normal and hyperthermic states. Prog. Brain Res., 115, 275-295.
22. 3H]iloprost. Neuroscience, 65, 493-503.
23. Miller, V.T., Coul, B.M., Yatsu, P.M., Shan, A.B. & Beamer, N.B. (1984) Prostacyclin infusion in an acute cerebral infarction. Neurology, 34, 1431-1435.
24. Mitani, A., Andou, Y., Masuda, S. & Kataoka, K. (1991) Transient forebrain ischemia of three-minute duration consistently induces severe neuronal damage in field CA1 of the hippocampus in the normothermic gerbils. Neurosci. Lett., 131, 171-174.
25. Moncada, S. (1982) Biological importance of prostacyclin. VIIIth Gaddum memorial lecture. Br. J. Pharmacol., 76, 3-31.
26. Mullane, K.M. & Moncada, S. (1980) Prostacyclin mediates the potentiated hypotensive effect of bradykinin following captopril treatment. Eur. J. Pharmacol., 66, 355-365.
27. Nitatori, T., Waguri, S., Karasawa, Y., Araki, H., Shibanai, K., Kominami, E. & Uchiyama, Y. (1995) Delayed neuronal death in the CA1 pyramidal cell layer of the gerbil hippocampus following transient ischemia is apoptosis. J. Neurosci., 15, 1001-1011.
28. Rukenstein, A., Rydel, R.E. & Green, L.A. (1991) Multiple agents rescue PC12 cells from serum-free cell death by translation- and transcription-independent mechanism. J. Neurosci., 11, 2552-2563.
29. Satoh, T., Numakawa, T., Abiru, Y., Yamagata, T., Ishikawa, Y., Enokido, Y. & Hatanaka, H. (1998) Production of reactive oxygen species and release of L-glutamate during superoxide anion-induced cell death of cerebellar granule neurons. J. Neurochem., 70, 316-324.
30. Satoh, T., Sakai, N., Enokido, Y., Uchiyama, Y. & Hatanaka, H. (1996) Survival factor-insensitive generation of reactive oxygen species induced by serum deprivation in neuronal cells. Brain Res., 733, 9-14.
31. Segal, R. & Greenberg, M.E. (1996) Intracellular signaling pathway activated by neurotrophic factors. Annu. Rev. Neurosci., 19, 463-489.
32. Simon, R.P., Swan, J.H., Griffith, T. & Meidrum, B.S. (1984) Blockage of N-methyl-D-aspartate receptor may protect against ischemic damage in the brain. Science, 226, 850-852.
33. 2 synthase antigen in smooth muscle cells. J. Biol. Chem., 258, 5922-5926.
34. Suzuki, M., Kato, K., Noyori, R., Watanabe, Yu, Takechi, H., Matsumura, K., Långström, B. & Watanabe, Y. (1996) (15R) -16-m-Tolyl-17,18,19,20-tetranoisocarbacyclin: a stable ligand with high binding affinity and selectivity for prostacyclin receptor in the central nervous system. Angew. Chem. Int. Ed. Engl., 35, 334-336.
35. Suzuki, M., Kato, K., Watanabe, Yu, Satoh, T., Matsumura, K., Watanabe, Y. & Noyori, R. (1999) 15-Deoxy-16-(m-tolyl)-17, 18, 19, 20-tetranoisocarbacyclin: a simple TIC derivatives with potent anti-apoptotic activity for neuronal cells. Chem. Commun., 307-308.
36. Takechi, H., Watanabe, Yu, Kato, K., Noyori, R., Suzuki, M. & Watanabe, Y. (1996) A novel subtype of the prostacyclin receptor expressed in the central nervous system. J. Biol. Chem., 271, 5901-5906.
37. 2 in the vascular action of histamine in dogs. J. Pharmacol. Exp. Ther., 223, 257-262.
38. 1 receptor agonist. Eur. J. Pharmacol., 302, 43-48.
39. 2A receptor agonist and antagonist. Eur. J. Pharmacol., 287, 295-302.
40. Watanabe, Yu, Matsumura, K., Takechi, H., Kato, K., Morii, H., Björkman, M., Långström, B., Noyori, R., Suzuki, M. & Watanabe, Y. (1999) A novel subtype of prostacyclin receptor in the central nervous system. J. Neurochem., 72, 2583-2592.
41. 11C-labeled stable prostacyclin receptor ligand studied by positron emission tomography. Neuroimage, 5, A1.
42. Yamada, M., Enokido, Y., Ikeuchi, T. and Hatanaka, H. (1995) Epidermal growth factor prevents oxygen-triggered apoptosis and induces sustained signaling in cultured rat cerebral cortical neurons. Eur. J. Neurosci. 7, 2130-2138.
43. Yoshida, S., Inoh, S., Asano, T., Sano, K., Shimasaki, H. & Ueta, N. (1983) Brain free fatty acids, edema, and mortality in gerbils subjected to transient, bilateral ischemia, and effect of barbiturate anesthesia. J. Neurochem., 40, 1278-1286.
44. Zang, L., Mitani, A., Yanase, H. & Kataoka, K. (1997) Continuous monitoring and regulating of brain temperature in the conscious and freely moving ischemic gerbils: effect of MK801 on delayed neuronal death in hippocampal CA1. J. Neurosci. Res., 47, 440-448.