Role of K(ATP)/+ channels and adenosine in regulation of coronary blood flow in the hypertrophied left ventricle

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 277, Issue 2 46-2, 1999, Pages

  Melchert, Peter J ^a   Duncker, Dirk J ^a,b   Traverse, Jay H ^a   Bache, Robert J ^a  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^b ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

8 phenyltheophylline; Aortic stenosis; ATP sensitive potassium channel; Glibenclamide; Left ventricular hypertrophy; Myocardium

Indexed keywords

ADENOSINE; ADENOSINE RECEPTOR; ADENOSINE TRIPHOSPHATE; GLIBENCLAMIDE; SODIUM; SODIUM CHANNEL;

ANIMAL EXPERIMENT; AORTA STENOSIS; ARTICLE; CORONARY ARTERY BLOOD FLOW; CORONARY ARTERY DILATATION; DOG; HEART LEFT VENTRICLE HYPERTROPHY; HEART RATE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BLOCKING; TREADMILL EXERCISE; VASCULAR SMOOTH MUSCLE;

EID: 0032859980     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.1999.277.2.h617     Document Type: Article

References (24)

1. Aversano, T., P. Ouyang, and H. Silverman. Blockade of the ATP-sensitive potassium channel modulates reactive hyperemia in the canine coronary circulation. Circ. Res. 69: 618-622, 1991.
2. Bache, R. J. Effects of hypertrophy on the coronary circulation. Prog. Cardiovasc. Dis. 31: 403-440, 1988.
3. Bache, R. J., X.-Z. Dai, J. S. Schwartz, and D. C. Homans. Role of adenosine in coronary vasodilation during exercise. Circ. Res. 62: 846-853, 1988.
4. Bache, R. J., T. R. Vrobel, W. S. Ring, R. W. Emery, and R. W. Anderson. Regional myocardial blood flow during exercise in dogs with chronic left ventricular hypertrophy. Circ. Res. 48: 76-87, 1981.
5. Ball, R. M., and R. J. Bache. Distribution of the myocardial blood flow in the exercising dog with restricted coronary artery inflow. Circ. Res. 38: 60-66, 1976.
6. Czarnowski, D., B. Wojcik, J. Langfort, and J. Gorski. 5′-Nucleotidase and adenosine deaminase activities in hypertrophied rat heart. The effect of tachycardia. Rocz. Akad. Med. Bialymst. 41: 334-340, 1996.
7. +-ATP channels in coronary vasodilation during exercise. Circulation 88: 1245-1253, 1993.
8. +ATP channels and adenosine in the regulation of coronary blood flow during exercise with normal and restricted coronary blood flow. J. Clin. Invest. 97: 996-1009, 1996.
9. ATP channel-blockade. J. Clin. Invest. 95: 285-295, 1995.
10. Duncker, D. J., J. Zhang, and R. J. Bache. Coronary pressure-flow relation in left ventricular hypertrophy. Circ. Res. 72: 579-587, 1993.
11. Duncker, D. J., J. Zhang, T. J. Pavek, M. J. Crampton, and R. J. Bache. Effect of exercise on coronary pressure-flow relationship in hypertrophied left ventricle. Am. J. Physiol. 269 (Heart Circ. Physiol. 38): H271-H281, 1995.
12. Ely, S. W., R. M. Knabb, A. N. Bacchus, R. Rubio, and R. M. Berne. Measurements of coronary plasma and pericardial infusate adenosine concentrations during exercise in conscious dogs: relationship to myocardial oxygen consumption and coronary blood flow. J. Mol. Cell. Cardiol. 15: 173-183, 1983.
13. Gwirtz, P. A. Construction and evaluation of a coronary catheter for chronic implantation in dogs. J. Appl. Physiol. 60: 720-726, 1986.
14. Ishida, T., R. M. Lewis, C. J. Hartley, M. L. Entman, and J. B. Field. Comparison of hepatic extraction of insulin and glucagon in conscious and anesthetized dogs. J. Endocrinol. 112: 1098-1109, 1983.
15. Kanatsuka, H., K. G. Lamping, C. L. Eastham, and M. L. Marcus. Heterogeneous changes in epimyocardial microvascular size during graded coronary stenosis: evidence of the microvascular site for autoregulation. Circ. Res. 66: 389-396, 1990.
16. Komaru, T., K. G. Lamping, C. L. Eastham, and K. C. Dellsperger. Role of ATP-sensitive potassium channels in coronary microvascular autoregulatory responses. Circ. Res. 69: 1146-1151, 1991.
17. Kuo, L., M. J. Davis, and W. M. Chilian. Myogenic activity in isolated subepicardial and subendocardial coronary arterioles. Am. J. Physiol. 255 (Heart Circ. Physiol. 24): H1558-H1562, 1988.
18. Laxson, D. D., D. C. Homans, and R. J. Bache. Inhibition of adenosine-mediated coronary vasodilation exacerbates myocardial ischemia during exercise. Am. J. Physiol. 265 (Heart Circ. Physiol. 34): H1471-H1477, 1993.
19. McKenzie, J. E., R. P. Steffen, and F. J. Haddy. Relationships between adenosine and coronary resistance in conscious exercising dogs. Am. J. Physiol. 242 (Heart Circ. Physiol. 11): H24-H29, 1982.
20. Numaguchi, K., K. Egashira, M. Sakata, H. Shimokawa, and A. Takeshita. Coronary vascular ATP-sensitive potassium channels are activated to a greater extent in spontaneously hypertensive rats than in Wistar-Kyoto rats. Hypertension 14: 183-189, 1996.
21. Rajagopalan, S., S. Dube, and J. M. Canty, Jr. Regulation of coronary diameter by myogenic mechanisms in arterial microvessels greater than 100 microns in diameter. Am. J. Physiol. 268 (Heart Circ. Physiol. 37): H788-H793, 1995.
22. Saito, D., C. R Steinhart, D. G. Nixon, and R. A. Olsson. Intracoronary adenosine deaminase reduces canine myocardial reactive hyperemia. Circ. Res. 49: 1262-1267, 1981.
23. Silver, P. J., K. Walus, and J. DiSalvo. Adenosine-mediated relaxation and activation of cyclic AMP-dependent protein kinase in coronary arterial smooth muscle. J. Pharmacol. Exp. Ther. 228: 342-347, 1984.
24. Zhang, J., H. Merkle, K. Hendrich, M. Garwood, A. H. L. From, K. Ugurbil, and R. J. Bache. Bioenergetic abnormalities associated with severe left ventricular hypertrophy. J. Clin. Invest. 92: 993-1003, 1993.