Synthesis and antiprotozoan properties of new 3,5-disubstituted- tetrahydro-2H-1,3,5-thiadiazine-2-thione derivatives

Arzneimittel-Forschung/Drug Research

Volumn 49, Issue 9, 1999, Pages 764-769

  Ochoa, Carmen ^a   Pérez, Eduardo ^b   Pérez, Roland ^b   Suárez, Margarita ^b   Ochoa, Estael ^b   Rodríguez, Hortensia ^b   Gómez Barrio, Alicia ^c   Muclas, Susana ^c   José Nogal, Juan ^c   Martínez, Rafael A ^c  

^a INSTITUTO DE QUÍMICA MÉDICA   (Spain)

^b UNIVERSITY OF HAVANA   (Cuba)

^c UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

Author keywords

2H 1,3,5 Thiadiazine 2 thione derivatives; Antiprotozoans; In vitro and in vivo studies; Synthesis; Trichomonas vaginalis; Trypanosoma cruzi

Indexed keywords

3,5 TETRAHYDRO 2H 1,3,5 THIADIAZINE 2 THIONE DERIVATIVE; THIADIAZINE DERIVATIVE; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ANTIPROTOZOAL ACTIVITY; ARTICLE; DERIVATIZATION; DRUG EFFECT; DRUG SYNTHESIS; HYDROPHILICITY; IN VITRO STUDY; TRICHOMONAS VAGINALIS; TRYPANOSOMA CRUZI;

EID: 0032859770     PISSN: 00044172     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0031-1300499     Document Type: Article

References (11)

1. Ertan, M., Bilgil, A. A., Palaska, E., Arzneim.-Forsch./Drug Res. 42 (I), 160 (1992), and references given therein
2. Schade, W., Rieche, A., Arch. Pharm. 299, 589 (1966)
3. Goksoyr, J., Acta Chem. Scand. 18, 1341 (1964)
4. Rieche, A., Hilgetag, G., Martini, A. et al., Arch. Pharm., 293, 957 (1960)
5. Zsolnai, T., Arzneim.-Forsch./Drug Res. 21, 121 (1971)
6. Weuffen, W. Martin, D., Schade, W. Pharmazie, 18, 420 (1963)
7. North, M. J., Mottram, J. C., Coombs, G. H., Parasitol. Today 6, 270. (1990)
8. Meirelles, M. N. L., Juliano, L., Carmona, E. et al., Mem. Inst. Oswaldo Cruz 85, 533 (1990)
9. Atienza, J., Martínez, R. A., Gómez Barrio, A. et al., Chemotherapy 38, 441 (1992)
10. Herrero, A., Ochoa, C., Atienza, J. et al., Arch. Pharm. 325, 509 (1992)
11. Nogal Ruiz, J. J., Escario, J. A., Martínez Díaz, R. A. et al., Parasite 2, 127 (1997)