메뉴 건너뛰기




Volumn 7, Issue 1, 1999, Pages 11-32

Genetically engineered polymers for drug delivery

Author keywords

Biosynthesis; Drug delivery; Genetic engineering; Polymers

Indexed keywords

DRUG CARRIER; POLYMER;

EID: 0032858428     PISSN: 1061186X     EISSN: None     Source Type: Journal    
DOI: 10.3109/10611869909085489     Document Type: Review
Times cited : (33)

References (113)
  • 1
    • 0025265147 scopus 로고
    • Site-directed mutagenesis in human tissue plasminogen activator: Distinguishing sites in the amino terminal region required for full fibrinolytic activity and rapid clearance from the circulation
    • Ahern, T.J., Morris, G.E., Barone, K.M., Morgan, P.G., Timony, G.A., Angus, L.B., Henson, K.S., Soudemire, J.B., Langer-Safer, P.R. and Larsen, G.R. (1990) Site-directed mutagenesis in human tissue plasminogen activator: distinguishing sites in the amino terminal region required for full fibrinolytic activity and rapid clearance from the circulation. J. Biol. Chem., 265, 5540-5545.
    • (1990) J. Biol. Chem. , vol.265 , pp. 5540-5545
    • Ahern, T.J.1    Morris, G.E.2    Barone, K.M.3    Morgan, P.G.4    Timony, G.A.5    Angus, L.B.6    Henson, K.S.7    Soudemire, J.B.8    Langer-Safer, P.R.9    Larsen, G.R.10
  • 2
    • 0030993566 scopus 로고    scopus 로고
    • Delivery of loperamide across the blood-brain barrier with polysorbate-80 coated polycyanoacrylate nanoparticles
    • Alyautdin, R.N., Petrov, V.E., Langer, K., Berthold, A., Kharkevich, D.A. and Kreuter, J. (1997) Delivery of loperamide across the blood-brain barrier with polysorbate-80 coated polycyanoacrylate nanoparticles. Pharm. Res., 14, 537-540.
    • (1997) Pharm. Res. , vol.14 , pp. 537-540
    • Alyautdin, R.N.1    Petrov, V.E.2    Langer, K.3    Berthold, A.4    Kharkevich, D.A.5    Kreuter, J.6
  • 4
    • 0027178252 scopus 로고
    • Hydrogel-based iontotherapeutic delivery devices for transdermal delivery of peptide protein drugs
    • Banga, A.K. and Chien, Y.W. (1995) Hydrogel-based iontotherapeutic delivery devices for transdermal delivery of peptide protein drugs. Pharm. Res., 10, 697-702.
    • (1995) Pharm. Res. , vol.10 , pp. 697-702
    • Banga, A.K.1    Chien, Y.W.2
  • 5
    • 78649334963 scopus 로고
    • Ionic and coordination chain (addition) polymerization
    • (New York: John Wiley and Sons)
    • Billmeyer Jr., F.W. (1984) Ionic and coordination chain (addition) polymerization, Textbook of Polymer Science (New York: John Wiley and Sons) pp. 82-100.
    • (1984) Textbook of Polymer Science , pp. 82-100
    • Billmeyer F.W., Jr.1
  • 6
    • 0028114851 scopus 로고
    • Improved biologic activity of antisense oligonucleotides conjugated to a fusogenic peptide
    • Bongartz, J.P., Aubertin, A.M., Milhaud, P.G. and Lebleu, B. (1994) Improved biologic activity of antisense oligonucleotides conjugated to a fusogenic peptide. Nucleic Acids Res., 22, 4681-4688.
    • (1994) Nucleic Acids Res. , vol.22 , pp. 4681-4688
    • Bongartz, J.P.1    Aubertin, A.M.2    Milhaud, P.G.3    Lebleu, B.4
  • 7
    • 0345360838 scopus 로고    scopus 로고
    • Proteins by design. Scientists create proteins that curl themselves up with a unique new twist
    • Borman, S. (1998) Proteins by design. Scientists create proteins that curl themselves up with a unique new twist. Chem. Eng. News, 76(47), 9.
    • (1998) Chem. Eng. News , vol.76 , Issue.47 , pp. 9
    • Borman, S.1
  • 8
    • 0023657397 scopus 로고
    • Determinants of messenger RNA stability
    • Brawerman, G. (1987) Determinants of messenger RNA stability. Cell, 48, 5-6.
    • (1987) Cell , vol.48 , pp. 5-6
    • Brawerman, G.1
  • 9
    • 0026574779 scopus 로고
    • Hydrogels for site-specific drug delivery to the colon: In vitro and in vivo degradation
    • Brøndsted, H. and Kopecek, J. (1995) Hydrogels for site-specific drug delivery to the colon: in vitro and in vivo degradation. Pharm. Res., 9, 1540-1545.
    • (1995) Pharm. Res. , vol.9 , pp. 1540-1545
    • Brøndsted, H.1    Kopecek, J.2
  • 11
    • 0002915441 scopus 로고
    • Microbial production of structural protein polymers
    • Mobley, D.P. (Ed.), (New York: Hanser Publishers)
    • Cappello, J. and Ferrari, F. (1994) Microbial production of structural protein polymers. In Mobley, D.P. (Ed.), Plastics from Microbes, (New York: Hanser Publishers) pp. 35-92.
    • (1994) Plastics from Microbes , pp. 35-92
    • Cappello, J.1    Ferrari, F.2
  • 12
    • 0000251981 scopus 로고    scopus 로고
    • Synthetically designed protein-based biomaterials
    • Park, K. (Ed.), (Washington, D.C.: American Chemical Society)
    • Cappello, J. (1997) Synthetically designed protein-based biomaterials. In Park, K. (Ed.), Controlled Drug Delivery: Challenges and Strategies (Washington, D.C.: American Chemical Society) pp. 439-453.
    • (1997) Controlled Drug Delivery: Challenges and Strategies , pp. 439-453
    • Cappello, J.1
  • 14
    • 0022144562 scopus 로고
    • Gene synthesis machines: DNA chemistry and its uses
    • Caruthers, M.H. (1985) Gene synthesis machines: DNA chemistry and its uses. Science, 230, 281-285.
    • (1985) Science , vol.230 , pp. 281-285
    • Caruthers, M.H.1
  • 15
    • 0026642155 scopus 로고
    • Facile resolution of N-tert-butoxy-carbonyl amino acids: The importance of enantiomeric purity in peptide synthesis
    • Chang, S.C., Wang, L.R. and Armstrong, D.W. (1992) Facile resolution of N-tert-butoxy-carbonyl amino acids: the importance of enantiomeric purity in peptide synthesis. J. Liq. Chrom., 15, 1411-1429.
    • (1992) J. Liq. Chrom. , vol.15 , pp. 1411-1429
    • Chang, S.C.1    Wang, L.R.2    Armstrong, D.W.3
  • 16
    • 0031195290 scopus 로고    scopus 로고
    • Controlled protein delivery from biodegradable tyrosine-containing poly(anhydride-co-imide) microspheres
    • Chiba, M., Hanes, J. and Langer, R. (1997) Controlled protein delivery from biodegradable tyrosine-containing poly(anhydride-co-imide) microspheres. Biomaterials, 18, 893-901.
    • (1997) Biomaterials , vol.18 , pp. 893-901
    • Chiba, M.1    Hanes, J.2    Langer, R.3
  • 17
    • 8244221666 scopus 로고    scopus 로고
    • Characterization and development of RGD-peptide-modified poly(lactic acid-co-lysine) as an interactive, resorbable biomaterial
    • Cook, A.D., Hrkach, J.S., Gao, N.N., Johnson, I.M., Pajvani, U.B., Cannizarro, S.M. and Langer, R. (1997) Characterization and development of RGD-peptide-modified poly(lactic acid-co-lysine) as an interactive, resorbable biomaterial. J. Biomed Mater. Res., 35, 513-523.
    • (1997) J. Biomed Mater. Res. , vol.35 , pp. 513-523
    • Cook, A.D.1    Hrkach, J.S.2    Gao, N.N.3    Johnson, I.M.4    Pajvani, U.B.5    Cannizarro, S.M.6    Langer, R.7
  • 20
    • 0000562513 scopus 로고    scopus 로고
    • Structural modification of a periodic polypeptide through biosynthetic replacement of proline with azetidine-2-carboxylic acid
    • Deming, T.J., Fournier, M.J., Mason, T.L. and Tirrell, D.A. (1996) Structural modification of a periodic polypeptide through biosynthetic replacement of proline with azetidine-2-carboxylic acid. Macromolecules, 29, 1442-1444.
    • (1996) Macromolecules , vol.29 , pp. 1442-1444
    • Deming, T.J.1    Fournier, M.J.2    Mason, T.L.3    Tirrell, D.A.4
  • 21
    • 0030887947 scopus 로고    scopus 로고
    • Transition metal-amine initiators for preparation of well-defined poly(γ-benzyl L-glutamate)
    • Deming, T.J. (1997a) Transition metal-amine initiators for preparation of well-defined poly(γ-benzyl L-glutamate). J. Am. Chem. Soc., 119, 2759-2760.
    • (1997) J. Am. Chem. Soc. , vol.119 , pp. 2759-2760
    • Deming, T.J.1
  • 22
    • 0031440842 scopus 로고    scopus 로고
    • Facile synthesis of block copolypeptides of defined architecture
    • Deming, T.J. (1997b) Facile synthesis of block copolypeptides of defined architecture. Nature, 390, 386-389.
    • (1997) Nature , vol.390 , pp. 386-389
    • Deming, T.J.1
  • 23
    • 0000305157 scopus 로고    scopus 로고
    • Amino acid derived nickelacyles: Intermediates in nickel-meiated polyeptide synthesis
    • Deming, T.J. (1998) Amino acid derived nickelacyles: intermediates in nickel-meiated polyeptide synthesis. J. Am. Chem. Soc., 120, 4240-4241.
    • (1998) J. Am. Chem. Soc. , vol.120 , pp. 4240-4241
    • Deming, T.J.1
  • 24
    • 0028036559 scopus 로고
    • Control of translation by mRNA secondary structure in Escherichia coli: A quantitative anlaysis of literature data
    • De Smit, M.H. and Van Duin, J. (1994) Control of translation by mRNA secondary structure in Escherichia coli: A quantitative anlaysis of literature data. J. Mol. Biol. 244(2) 144-150.
    • (1994) J. Mol. Biol. , vol.244 , Issue.2 , pp. 144-150
    • De Smit, M.H.1    Van Duin, J.2
  • 25
    • 0025966705 scopus 로고
    • A novel approach to the preparation of pH-sensitive hydrogels for enteric drug delivery
    • Dong, L.-C. and Hoffman, A.S. (1991) A novel approach to the preparation of pH-sensitive hydrogels for enteric drug delivery. J. Controlled Release, 15, 141-152.
    • (1991) J. Controlled Release , vol.15 , pp. 141-152
    • Dong, L.-C.1    Hoffman, A.S.2
  • 26
    • 0029892121 scopus 로고    scopus 로고
    • Optimizing inducer and culture conditions for expression of foreign proteins under the control of the lac promoter
    • Donovan, R.S., Robinson, C.W. and Glick, B.R. (1996) Optimizing inducer and culture conditions for expression of foreign proteins under the control of the lac promoter. Microbiol., 169, 145-154.
    • (1996) Microbiol. , vol.169 , pp. 145-154
    • Donovan, R.S.1    Robinson, C.W.2    Glick, B.R.3
  • 27
    • 0027556206 scopus 로고
    • Synthesis of a genetically engineered repetitive polypeptide containing periodic selenomethionine residues
    • Dougherty, M.J., Kothakota, S., Mason, T.L., Tirrell, D.A. and Fournier, M.J. (1993) Synthesis of a genetically engineered repetitive polypeptide containing periodic selenomethionine residues. Macromolecules, 26, 1779-1781.
    • (1993) Macromolecules , vol.26 , pp. 1779-1781
    • Dougherty, M.J.1    Kothakota, S.2    Mason, T.L.3    Tirrell, D.A.4    Fournier, M.J.5
  • 28
    • 0020682412 scopus 로고
    • Targeting of N-(2-hydroxypropyl)methacrylamide copolymers to liver by incorporation of galactose residues
    • Duncan, R., Kopecek, J., Rejmanova, P. and Lloyd, J.B. (1983) Targeting of N-(2-hydroxypropyl)methacrylamide copolymers to liver by incorporation of galactose residues. Biochim. Biophys. Acta, 755, 518-521.
    • (1983) Biochim. Biophys. Acta , vol.755 , pp. 518-521
    • Duncan, R.1    Kopecek, J.2    Rejmanova, P.3    Lloyd, J.B.4
  • 29
    • 0021271357 scopus 로고
    • Tyrosinamide residues enhance pinocytotic capture of N-(2-hydroxypropyl)methacrylamide copolymers
    • Duncan, R., Cable, H.C., Rejmanova, P., Kopocek, J. and Lloyd, J.B. (1984) Tyrosinamide residues enhance pinocytotic capture of N-(2-hydroxypropyl)methacrylamide copolymers. Biochim. Biophys. Acta, 799, 1-8.
    • (1984) Biochim. Biophys. Acta , vol.799 , pp. 1-8
    • Duncan, R.1    Cable, H.C.2    Rejmanova, P.3    Kopocek, J.4    Lloyd, J.B.5
  • 30
    • 0005106988 scopus 로고
    • Selective endocytosis of macromolecular drug carriers
    • Robinson, J.R. and Lee, V.H.L. (Eds.), (New York: Marcel Dekker)
    • Duncan, R. (1987) Selective endocytosis of macromolecular drug carriers. In Robinson, J.R. and Lee, V.H.L. (Eds.), Controlled Drug Delivery: Fundamentals and Applications (New York: Marcel Dekker) pp. 581-621.
    • (1987) Controlled Drug Delivery: Fundamentals and Applications , pp. 581-621
    • Duncan, R.1
  • 31
    • 0028934457 scopus 로고
    • Carbamylation decreases the cytotoxicity but not the drug carrier properties of polylysines
    • Ekrami, H.M. and Shen, W.C. (1995) Carbamylation decreases the cytotoxicity but not the drug carrier properties of polylysines. J. Drug Target., 2, 469-475.
    • (1995) J. Drug Target , vol.2 , pp. 469-475
    • Ekrami, H.M.1    Shen, W.C.2
  • 32
    • 0026342056 scopus 로고
    • Biosynthetic method for introducing unnatural amino acids site-specifically into proteins
    • Ellman, J., Mandel, D., Anthony-Cahill, S., Noren, C.J. and Shultz, P.G. (1991) Biosynthetic method for introducing unnatural amino acids site-specifically into proteins. Methods Enzymol., 202, 301-336.
    • (1991) Methods Enzymol. , vol.202 , pp. 301-336
    • Ellman, J.1    Mandel, D.2    Anthony-Cahill, S.3    Noren, C.J.4    Shultz, P.G.5
  • 35
    • 0024439808 scopus 로고
    • Evaluation of protein-N-(2-hydroxypropyl)methacrylamide copolymer conjugates as targetable drug carriers. 1. Binding, pinocytic uptake, and intracellular distribution of transferrin and anti-transferrin receptor antibody conjugates
    • Flanagan, P.A., Kopeckova, P., Kopecek, J. and Duncan, R. (1989) Evaluation of protein-N-(2-hydroxypropyl)methacrylamide copolymer conjugates as targetable drug carriers. 1. Binding, pinocytic uptake, and intracellular distribution of transferrin and anti-transferrin receptor antibody conjugates. Biochim. Biophys. Acta, 993, 83-91.
    • (1989) Biochim. Biophys. Acta , vol.993 , pp. 83-91
    • Flanagan, P.A.1    Kopeckova, P.2    Kopecek, J.3    Duncan, R.4
  • 39
    • 0031777866 scopus 로고    scopus 로고
    • Genetic engineering of protein-based polymers: Potential in controlled drug delivery
    • Ghandehari, H. and Cappello, J. (1998) Genetic engineering of protein-based polymers: potential in controlled drug delivery. Pharm. Res., 15, 813-815.
    • (1998) Pharm. Res. , vol.15 , pp. 813-815
    • Ghandehari, H.1    Cappello, J.2
  • 41
    • 0032553587 scopus 로고    scopus 로고
    • High resolution protein design with backbone freedom
    • Harbury, P.B., Plecs, J.J., Tidor, B., Alber, T. and Kim, P.S. (1998) High resolution protein design with backbone freedom. Science, 282, 1462-1467.
    • (1998) Science , vol.282 , pp. 1462-1467
    • Harbury, P.B.1    Plecs, J.J.2    Tidor, B.3    Alber, T.4    Kim, P.S.5
  • 42
    • 0031481465 scopus 로고    scopus 로고
    • Toward uniform polymer architecture through stereospecific living polymerization and chromatographic separation technique
    • Hatada, K., Nishiura, T., Kitayama, T. and Ute, K. (1997) Toward uniform polymer architecture through stereospecific living polymerization and chromatographic separation technique. Macromol. Symp., 118, 135-141.
    • (1997) Macromol. Symp. , vol.118 , pp. 135-141
    • Hatada, K.1    Nishiura, T.2    Kitayama, T.3    Ute, K.4
  • 44
    • 0030983421 scopus 로고    scopus 로고
    • Expression of a synthetic protein-based polymer (elastomer) gene in Aspergillus nidulans
    • Herzog, R.W., Singh, N.K., Urry, D.W. and Daniell, H. (1997) Expression of a synthetic protein-based polymer (elastomer) gene in Aspergillus nidulans. App. Microbiol. Biotechnol., 47, 368-372.
    • (1997) App. Microbiol. Biotechnol. , vol.47 , pp. 368-372
    • Herzog, R.W.1    Singh, N.K.2    Urry, D.W.3    Daniell, H.4
  • 45
    • 0029192318 scopus 로고
    • An attempt to control the monomer sequence distribution in copolymers of isophthalic acid, terephthalic acid, and bisphenols prepared by the use of diphenyl chlorophosphate in pyridine
    • Higashi, F., Watabiki, M. and Kimura, K. (1995) An attempt to control the monomer sequence distribution in copolymers of isophthalic acid, terephthalic acid, and bisphenols prepared by the use of diphenyl chlorophosphate in pyridine. J. Polym. Sci. Part A: Polym. Chem., 33, 185-188.
    • (1995) J. Polym. Sci. Part A: Polym. Chem. , vol.33 , pp. 185-188
    • Higashi, F.1    Watabiki, M.2    Kimura, K.3
  • 46
    • 0025619566 scopus 로고
    • Purification of recombinant proteins with metal chelate adsorbent
    • Setlow, J. (Ed.) (New York: Plenum press)
    • Hochuli, E. (1990) Purification of recombinant proteins with metal chelate adsorbent. In Setlow, J. (Ed.) Genetic Engineering, Principles and Practice, Vol. 12 (New York: Plenum press) pp. 87-98.
    • (1990) Genetic Engineering, Principles and Practice, Vol. 12 , vol.12 , pp. 87-98
    • Hochuli, E.1
  • 47
    • 0023581602 scopus 로고
    • Applications of thermally reversible polymers and hydrogels in therapeutics and diagnostics
    • Hoffman, A.S. (1987) Applications of thermally reversible polymers and hydrogels in therapeutics and diagnostics. J. Controlled Release, 6, 297-305.
    • (1987) J. Controlled Release , vol.6 , pp. 297-305
    • Hoffman, A.S.1
  • 48
  • 49
    • 0027344972 scopus 로고
    • Influence of carrier on biodistribution and in vitro cytotoxicity of methotrexatebranched polypeptide conjugates
    • Hudecz, F., Clegg, J.A., Kajtar, J., Embleton, M.J., Pimm, M., Szekerke, M. and Baldwin, R.W. (1993) Influence of carrier on biodistribution and in vitro cytotoxicity of methotrexatebranched polypeptide conjugates. Bioconjugate Chem., 4, 25-33.
    • (1993) Bioconjugate Chem. , vol.4 , pp. 25-33
    • Hudecz, F.1    Clegg, J.A.2    Kajtar, J.3    Embleton, M.J.4    Pimm, M.5    Szekerke, M.6    Baldwin, R.W.7
  • 51
    • 0030828489 scopus 로고    scopus 로고
    • Highly porous polymer matrices as a three-dimensional culture system for hepatocytes
    • Kaufmann, P.M., Heimrath, S., Kim, B.S. and Mooney, D.J. (1997) Highly porous polymer matrices as a three-dimensional culture system for hepatocytes. Cell Transplant, 6, 463-468.
    • (1997) Cell Transplant , vol.6 , pp. 463-468
    • Kaufmann, P.M.1    Heimrath, S.2    Kim, B.S.3    Mooney, D.J.4
  • 52
    • 0030901987 scopus 로고    scopus 로고
    • In vitro gene expression on smooth muscle cells using a terplex delivery system
    • Kim, J.S., Maruyama, A., Akaike, T. and Kim, S.W. (1997) In vitro gene expression on smooth muscle cells using a terplex delivery system. J. Controlled Release, 47, 51-59.
    • (1997) J. Controlled Release , vol.47 , pp. 51-59
    • Kim, J.S.1    Maruyama, A.2    Akaike, T.3    Kim, S.W.4
  • 53
    • 0029234588 scopus 로고
    • Preparation of highly stereoregular poly(methacrylic acid) by stereospecific anionic polymerization of trimethylsilyl methacrylate
    • Kitayama, T., He, S., Hironaka, Y., Iijima, T. and Hatada, K. (1995) Preparation of highly stereoregular poly(methacrylic acid) by stereospecific anionic polymerization of trimethylsilyl methacrylate. Polym. J., 27, 314-318.
    • (1995) Polym. J. , vol.27 , pp. 314-318
    • Kitayama, T.1    He, S.2    Hironaka, Y.3    Iijima, T.4    Hatada, K.5
  • 54
    • 0002911289 scopus 로고
    • Enzymatically degradable bonds in synthetic polymers
    • Bruck, S.D. (Ed.) (Boca Raton, Florida: CRC Press)
    • Kopecek, J. and Rejmanova, P. (1983) Enzymatically degradable bonds in synthetic polymers. In Bruck, S.D. (Ed.) Controlled Drug Delivery, Vol. I (Boca Raton, Florida: CRC Press) pp. 81-124.
    • (1983) Controlled Drug Delivery, Vol. I , vol.1 , pp. 81-124
    • Kopecek, J.1    Rejmanova, P.2
  • 55
    • 0028074620 scopus 로고
    • Chemical sequence control of β-sheet assembly in macromolecular crystals of periodic polypeptides
    • Krejchi, M.T., Atkins, E.D.T., Waddon, A.J., Fournier, M.J., Mason, T.L. and Tirrell, D.A. (1994) Chemical sequence control of β-sheet assembly in macromolecular crystals of periodic polypeptides. Science, 265, 1427-1432.
    • (1994) Science , vol.265 , pp. 1427-1432
    • Krejchi, M.T.1    Atkins, E.D.T.2    Waddon, A.J.3    Fournier, M.J.4    Mason, T.L.5    Tirrell, D.A.6
  • 56
    • 0030911009 scopus 로고    scopus 로고
    • Biosynthesis and chemical reactions of poly(amino acid)s from microorganisms
    • Kunioka, M. (1997) Biosynthesis and chemical reactions of poly(amino acid)s from microorganisms. Appl. Microbiol. Biotech., 47, 469-475.
    • (1997) Appl. Microbiol. Biotech. , vol.47 , pp. 469-475
    • Kunioka, M.1
  • 57
    • 0029360757 scopus 로고
    • Block copolymer micelles as long-circulating drug vehicles
    • Kwon, G.S. and Kataoka, K. (1995) Block copolymer micelles as long-circulating drug vehicles. Adv. Drug Delivery Rev., 16, 295-309.
    • (1995) Adv. Drug Delivery Rev. , vol.16 , pp. 295-309
    • Kwon, G.S.1    Kataoka, K.2
  • 58
    • 0001855042 scopus 로고
    • Controlled release of bioactive agents from lactide/glycolide polymers
    • Chasin, M. and Langer, R. (Eds.) (New York: Marcel Dekker)
    • Lewis, D.H. (1990) Controlled release of bioactive agents from lactide/glycolide polymers. In Chasin, M. and Langer, R. (Eds.) Biodegradable Polymers as Drug Delivery Systems (New York: Marcel Dekker) pp. 1-41.
    • (1990) Biodegradable Polymers As Drug Delivery Systems , pp. 1-41
    • Lewis, D.H.1
  • 59
    • 0030569152 scopus 로고    scopus 로고
    • Enzymatic degradability of poly(lactide): Effects of chain stereochemistry and material crystallinity
    • MacDonald, R.T., McCarthy, S.P. and Gross, R.A. (1996) Enzymatic degradability of poly(lactide): effects of chain stereochemistry and material crystallinity. Macromolecules, 29, 7356-7361.
    • (1996) Macromolecules , vol.29 , pp. 7356-7361
    • MacDonald, R.T.1    McCarthy, S.P.2    Gross, R.A.3
  • 60
    • 0003130873 scopus 로고
    • Pathways of homologous recombination in Escherichia coli
    • Kucherlapati, R. and Smith, G.R. (Eds.), (Washington, D.C.: American Society for Microbiology)
    • Mahajan, S.K. (1988) Pathways of homologous recombination in Escherichia coli. In Kucherlapati, R. and Smith, G.R. (Eds.), Genetic Recombination (Washington, D.C.: American Society for Microbiology) pp. 88-140.
    • (1988) Genetic Recombination , pp. 88-140
    • Mahajan, S.K.1
  • 61
    • 0022858683 scopus 로고
    • A new concept for macromolecular therapeutics in cancer chemotherapy: Mechanism of tumoritropic accumulation of proteins and the antitumor agent SMANCS
    • Matsumura, Y. and Maeda, H. (1986) A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent SMANCS. Cancer Res., 46, 6387-6392.
    • (1986) Cancer Res. , vol.46 , pp. 6387-6392
    • Matsumura, Y.1    Maeda, H.2
  • 65
    • 0025428787 scopus 로고
    • Chemical and biosynthetic approaches to the production of novel polypeptide materials
    • McGrath, K.P., Tirrell, D.A., Kawai, M., Mason, T.L. and Fournier, M.J. (1990) Chemical and biosynthetic approaches to the production of novel polypeptide materials. Biotechnol. Prog., 6, 186-192.
    • (1990) Biotechnol. Prog. , vol.6 , pp. 186-192
    • McGrath, K.P.1    Tirrell, D.A.2    Kawai, M.3    Mason, T.L.4    Fournier, M.J.5
  • 68
    • 0023081413 scopus 로고
    • Sequence instability in the long terminal repeats of avian spleen necrosis virus and reticuloendotheliosis virus
    • Notani, G. and Sauerbrier, W. (1987) Sequence instability in the long terminal repeats of avian spleen necrosis virus and reticuloendotheliosis virus. J. Mol. Evol., 25, 241-247.
    • (1987) J. Mol. Evol. , vol.25 , pp. 241-247
    • Notani, G.1    Sauerbrier, W.2
  • 69
    • 0023212748 scopus 로고
    • Binding and internalization by cultured cells of neocarzinostatin and enhancement of its actions by conjugation with lipophilic styrene-maleic acid copolymer
    • Oda, T. and Maeda, H. (1987) Binding and internalization by cultured cells of neocarzinostatin and enhancement of its actions by conjugation with lipophilic styrene-maleic acid copolymer. Cancer Res., 47, 3206-3211.
    • (1987) Cancer Res. , vol.47 , pp. 3206-3211
    • Oda, T.1    Maeda, H.2
  • 71
    • 0024309206 scopus 로고
    • Effect of galactose on interaction of N-(2-hydroxypropyl) methacrylamide copolymers with hepatoma cells in culture: Preliminary application to an anticancer agent, daunomycin
    • O'Hare, K.B., Huma, I.C., Scarlett, L., Chytry, V., Kopeckova, P., Kopecek, J. and Duncan, R. (1989) Effect of galactose on interaction of N-(2-hydroxypropyl) methacrylamide copolymers with hepatoma cells in culture: preliminary application to an anticancer agent, daunomycin. Hepatology 10, 207-214.
    • (1989) Hepatology , vol.10 , pp. 207-214
    • O'Hare, K.B.1    Huma, I.C.2    Scarlett, L.3    Chytry, V.4    Kopeckova, P.5    Kopecek, J.6    Duncan, R.7
  • 73
    • 0023710969 scopus 로고
    • Enzyme-digestible swelling hydrogels as platforms for long-term oral drug delivery: Synthesis and characterization
    • Park, K. (1988) Enzyme-digestible swelling hydrogels as platforms for long-term oral drug delivery: synthesis and characterization. Biomaterials, 9, 435-441.
    • (1988) Biomaterials , vol.9 , pp. 435-441
    • Park, K.1
  • 74
    • 0030152727 scopus 로고    scopus 로고
    • In vitro cell response to differences in poly L lactide crystallinity
    • Park, A. and Cima, L.G. (1996) In vitro cell response to differences in poly L lactide crystallinity. J. Biomed Mater. Res., 31, 117-130.
    • (1996) J. Biomed Mater. Res. , vol.31 , pp. 117-130
    • Park, A.1    Cima, L.G.2
  • 76
    • 0023899705 scopus 로고
    • Structural plasmid instability in Bacillus subtilis: Effect of direct and inverted repeats
    • Peeters, B.P., de Boer, J.H., Bron, S. and Venema, G. (1988) Structural plasmid instability in Bacillus subtilis: effect of direct and inverted repeats. Mol. Gen. Genet., 212, 450-458.
    • (1988) Mol. Gen. Genet. , vol.212 , pp. 450-458
    • Peeters, B.P.1    De Boer, J.H.2    Bron, S.3    Venema, G.4
  • 77
    • 0021271957 scopus 로고
    • Cell attachment activity of fibronectin can be duplicated by small synthetic fragments of the molecule
    • Pierschbacher, M.D. and Ruoslahti, E. (1984) Cell attachment activity of fibronectin can be duplicated by small synthetic fragments of the molecule. Nature, 309, 30-33.
    • (1984) Nature , vol.309 , pp. 30-33
    • Pierschbacher, M.D.1    Ruoslahti, E.2
  • 78
    • 0032541038 scopus 로고    scopus 로고
    • Reversible hydrogels from self-assembling artificial proteins
    • Petka, W.A., Harden, J.L., McGrath, K.P., Wirtz, D. and Tirrell, D.A. (1998) Reversible hydrogels from self-assembling artificial proteins. Science, 281, 389-392.
    • (1998) Science , vol.281 , pp. 389-392
    • Petka, W.A.1    Harden, J.L.2    McGrath, K.P.3    Wirtz, D.4    Tirrell, D.A.5
  • 79
    • 0029339453 scopus 로고    scopus 로고
    • Enantioselective release of 5-fluorouracil from N-(2-hydroxypropyl)amide-based copolymers via lysosomal enzymes
    • Putnam, D. and Kopecek, J. (1996) Enantioselective release of 5-fluorouracil from N-(2-hydroxypropyl)amide-based copolymers via lysosomal enzymes. Bioconjugate Chem., 6, 483-492.
    • (1996) Bioconjugate Chem. , vol.6 , pp. 483-492
    • Putnam, D.1    Kopecek, J.2
  • 80
    • 0030603965 scopus 로고    scopus 로고
    • Intracellularly biorecognizable derivatives of 5-flourouracil. Implications for site-specific delivery in the human condition
    • Putnam, D., Shiah, J.G. and Kopecek. J. (1996) Intracellularly biorecognizable derivatives of 5-flourouracil. Implications for site-specific delivery in the human condition. Biochem. Pharmacol., 52, 957-962.
    • (1996) Biochem. Pharmacol. , vol.52 , pp. 957-962
    • Putnam, D.1    Shiah, J.G.2    Kopecek, J.3
  • 81
    • 0026331606 scopus 로고
    • Prediction of alpha helices and t cell-presented sequences in proteins with algorithms based on strip-of-helix hydrophobicity index
    • Reyes, V.E., Lew, R.A., Lu, S. and Humphreys, R.E. (1991) Prediction of alpha helices and T cell-presented sequences in proteins with algorithms based on strip-of-helix hydrophobicity index. Methods Enzymol., 202, 225-238.
    • (1991) Methods Enzymol. , vol.202 , pp. 225-238
    • Reyes, V.E.1    Lew, R.A.2    Lu, S.3    Humphreys, R.E.4
  • 82
    • 0021274948 scopus 로고
    • Effect of chemical structure of N-(2-hydroxypropyl)methacrylamide copolymers on their ability to induce antibody formation in inbred strains of mice
    • Rihova, B., Kopecek, J., Ulbrich, K., Poposil, M. and Mancal, P. (1984) Effect of chemical structure of N-(2-hydroxypropyl)methacrylamide copolymers on their ability to induce antibody formation in inbred strains of mice. Biomaterials, 5, 143-148.
    • (1984) Biomaterials , vol.5 , pp. 143-148
    • Rihova, B.1    Kopecek, J.2    Ulbrich, K.3    Poposil, M.4    Mancal, P.5
  • 83
    • 0023930539 scopus 로고
    • Antibody-directed affinity therapy applied to the immune system: In vivo effectiveness and limited cytotoxicity of daunomycin conjugated to HPMA copolymers and targeting antibody
    • Rihova, B., Kopeckova, P., Strohalm, J., Rossmann, P., Vetvicka, V. and Kopecek, J. (1988) Antibody-directed affinity therapy applied to the immune system: in vivo effectiveness and limited cytotoxicity of daunomycin conjugated to HPMA copolymers and targeting antibody. Clin. Immunol. Immunopathol., 46, 100-114.
    • (1988) Clin. Immunol. Immunopathol. , vol.46 , pp. 100-114
    • Rihova, B.1    Kopeckova, P.2    Strohalm, J.3    Rossmann, P.4    Vetvicka, V.5    Kopecek, J.6
  • 85
    • 0027187693 scopus 로고
    • The effect of the monomer sequence distribution on the photooxidation of styrene-acrylonitrile copolymers
    • Sargent, M., Koenig, J.L. and Maecker, N.L. (1993) The effect of the monomer sequence distribution on the photooxidation of styrene-acrylonitrile copolymers. Polym. Degrad. Stab., 39, 309-316.
    • (1993) Polym. Degrad. Stab. , vol.39 , pp. 309-316
    • Sargent, M.1    Koenig, J.L.2    Maecker, N.L.3
  • 86
    • 0030033489 scopus 로고    scopus 로고
    • Temperature and pH-sensitive polymers for human calcitonin delivery
    • Serres, A., Baudys, M. and Kim, S.W. (1997) Temperature and pH-sensitive polymers for human calcitonin delivery. Pharm. Res., 13, 196-201.
    • (1997) Pharm. Res. , vol.13 , pp. 196-201
    • Serres, A.1    Baudys, M.2    Kim, S.W.3
  • 87
    • 0032499311 scopus 로고    scopus 로고
    • Determination of monomer reactivity ratios for copolymerizations of methacrylic acid with poly(ethylene glycol) monomethacrylate
    • Smith, B.L. and Klier, J. (1998) Determination of monomer reactivity ratios for copolymerizations of methacrylic acid with poly(ethylene glycol) monomethacrylate. J. Appl. Polym. Sci., 68, 1019-1025.
    • (1998) J. Appl. Polym. Sci. , vol.68 , pp. 1019-1025
    • Smith, B.L.1    Klier, J.2
  • 89
    • 0002079949 scopus 로고
    • Disposition and tumor-localization of mitomycin c-dextran conjugates in mice
    • Takakura, Y., Takagi, A., Hashida, M. and Sezaki, H. (1987) Disposition and tumor-localization of mitomycin c-dextran conjugates in mice. Pharm. Res., 4, 293-300.
    • (1987) Pharm. Res. , vol.4 , pp. 293-300
    • Takakura, Y.1    Takagi, A.2    Hashida, M.3    Sezaki, H.4
  • 90
    • 0025148495 scopus 로고
    • Disposition characteristics of macromolecules in tumor-bearing mice
    • Takakura, Y., Fujita, T., Hashida, M. and Sezaki, H. (1990) Disposition characteristics of macromolecules in tumor-bearing mice. Pharm. Res., 7, 339-346.
    • (1990) Pharm. Res. , vol.7 , pp. 339-346
    • Takakura, Y.1    Fujita, T.2    Hashida, M.3    Sezaki, H.4
  • 91
    • 0029895325 scopus 로고    scopus 로고
    • Macromolecular carrier systems for targeted drug delivery: Pharmacokinetic considerations on biodistribution
    • Takakura, Y. and Hashida, M. (1996) Macromolecular carrier systems for targeted drug delivery: Pharmacokinetic considerations on biodistribution. Pharm. Res., 13, 820-831.
    • (1996) Pharm. Res. , vol.13 , pp. 820-831
    • Takakura, Y.1    Hashida, M.2
  • 92
    • 0026878369 scopus 로고
    • The effect of lipase on the release of naltrexone from triglyceride-coated cellulose acetate phthalate
    • Tefft, J.A., Roskos, K.V. and Heller, J. (1992) The effect of lipase on the release of naltrexone from triglyceride-coated cellulose acetate phthalate. J. Biomed. Mat. Res., 26, 713-724.
    • (1992) J. Biomed. Mat. Res. , vol.26 , pp. 713-724
    • Tefft, J.A.1    Roskos, K.V.2    Heller, J.3
  • 94
    • 0027630815 scopus 로고
    • Chemically optimized antimyosin Fab conjugates with chelating polymers: Importance of the nature of the protein-polymer single site covalent bond for biodistribution and infarction localization
    • Trubetskoy, V.S., Narula, J., An Khaw, B. and Torchillin, V.R. (1993) Chemically optimized antimyosin Fab conjugates with chelating polymers: Importance of the nature of the protein-polymer single site covalent bond for biodistribution and infarction localization. Bioconjug. Chem., 4, 251-255.
    • (1993) Bioconjug. Chem. , vol.4 , pp. 251-255
    • Trubetskoy, V.S.1    Narula, J.2    An Khaw, B.3    Torchillin, V.R.4
  • 96
    • 0026468684 scopus 로고
    • Free energy transduction in polypeptides and proteins
    • Urry, D.W. (1992) Free energy transduction in polypeptides and proteins. Prog. Biophys. Mol. Biol., 57, 23-57.
    • (1992) Prog. Biophys. Mol. Biol. , vol.57 , pp. 23-57
    • Urry, D.W.1
  • 97
    • 0026848928 scopus 로고
    • Hydrophobicity-induced pKa shifts in elastin protein-based polymers
    • Urry, D.W., Peng, S.Q. and Parker, T.M. (1992) Hydrophobicity-induced pKa shifts in elastin protein-based polymers. Biopolymers, 32, 373-379.
    • (1992) Biopolymers , vol.32 , pp. 373-379
    • Urry, D.W.1    Peng, S.Q.2    Parker, T.M.3
  • 99
    • 0002664092 scopus 로고
    • Comparison of electrostatic- and hydrophobic-induced pKa shifts in polypentapeptides. The lysine residue
    • Urry, D.W., Peng, S.Q., Gowda, D.C., Parker, T.M., and Harris, R.D. (1994) Comparison of electrostatic- and hydrophobic-induced pKa shifts in polypentapeptides. The lysine residue. Chem. Phys. Lett., 225, 97-103.
    • (1994) Chem. Phys. Lett. , vol.225 , pp. 97-103
    • Urry, D.W.1    Peng, S.Q.2    Gowda, D.C.3    Parker, T.M.4    Harris, R.D.5
  • 101
    • 0029850480 scopus 로고    scopus 로고
    • Temperature- and pH-sensitive terpolymers for modulated delivery of streptokinase
    • Vakkalanka, S.K., Brazel, C.S. and Peppas, N.A. (1996) Temperature- and pH-sensitive terpolymers for modulated delivery of streptokinase. J. Biomed. Sci. Polym. Ed., 8, 119-129.
    • (1996) J. Biomed. Sci. Polym. Ed. , vol.8 , pp. 119-129
    • Vakkalanka, S.K.1    Brazel, C.S.2    Peppas, N.A.3
  • 102
    • 0027988268 scopus 로고
    • Immunogenicity of poly-D-lysine, a potential polymeric drug carrier
    • Vermeersch, H. and Remon, J.P. (1994) Immunogenicity of poly-D-lysine, a potential polymeric drug carrier. J. Controlled Release, 32, 225-229.
    • (1994) J. Controlled Release , vol.32 , pp. 225-229
    • Vermeersch, H.1    Remon, J.P.2
  • 103
    • 0033521939 scopus 로고    scopus 로고
    • Hybrid hydrogels assembled from synthetic polymers and coiled-coil protein domains
    • Wang, C., Stewart, R. and Kopecek, J. (1999) Hybrid hydrogels assembled from synthetic polymers and coiled-coil protein domains. Nature, 397, 417-420.
    • (1999) Nature , vol.397 , pp. 417-420
    • Wang, C.1    Stewart, R.2    Kopecek, J.3
  • 104
    • 0022654731 scopus 로고
    • An inverted repeat sequence of the IncFl plasmid ColV2-K94 increases multimerization-mediated plasmid instability
    • Weber, P.C. and Palchaudhuri, S. (1986) An inverted repeat sequence of the IncFl plasmid ColV2-K94 increases multimerization-mediated plasmid instability. J. Gen. Microbiol., 132, 989-995.
    • (1986) J. Gen. Microbiol. , vol.132 , pp. 989-995
    • Weber, P.C.1    Palchaudhuri, S.2
  • 105
    • 0023133803 scopus 로고
    • Yeast phosphoglycerate kinase: Investigtion of catalytic function by site directed mutagenesis
    • Wilson, C.A.B., Hardman, N., Fothergill-Gilmore, L.A., Gamblin, S.J. and Watson, H.C. (1987) Yeast phosphoglycerate kinase: investigtion of catalytic function by site directed mutagenesis. J. Biochem., 241, 609-614.
    • (1987) J. Biochem. , vol.241 , pp. 609-614
    • Wilson, C.A.B.1    Hardman, N.2    Fothergill-Gilmore, L.A.3    Gamblin, S.J.4    Watson, H.C.5
  • 106
    • 0020036666 scopus 로고
    • Cytoplasmic inclusion bodies in Escherichia coli producing biosynthetic human insulin proteins
    • Williams, D.C., Van Frank, R.M., Muth, W.L. and Burnett, J.P. (1982) Cytoplasmic inclusion bodies in Escherichia coli producing biosynthetic human insulin proteins. Science, 215, 687-688.
    • (1982) Science , vol.215 , pp. 687-688
    • Williams, D.C.1    Van Frank, R.M.2    Muth, W.L.3    Burnett, J.P.4
  • 107
    • 0030574966 scopus 로고    scopus 로고
    • Ternary phase diagrams of poly(styrene-co-methylmethacrylate), poly(methylmethacrylate), and polystyrene: Monomer sequence distribution effect and encapsulation
    • Winey, K.I., Berba, M.L. and Galvin, M.E. (1996) Ternary phase diagrams of poly(styrene-co-methylmethacrylate), poly(methylmethacrylate), and polystyrene: monomer sequence distribution effect and encapsulation. Macromolecules, 29, 2868-2877.
    • (1996) Macromolecules , vol.29 , pp. 2868-2877
    • Winey, K.I.1    Berba, M.L.2    Galvin, M.E.3
  • 108
    • 0030890748 scopus 로고    scopus 로고
    • Design, synthesis, and characterization of a cationic peptide that binds to nucleic acids and permeabilizes bilayers
    • Wyman, T.B., Nicol, F., Zelphati, O., Sciara, P.V., Plank, C. and Szoka Jr., F.C. (1997) Design, synthesis, and characterization of a cationic peptide that binds to nucleic acids and permeabilizes bilayers. Biochemistry, 36, 3008-3017.
    • (1997) Biochemistry , vol.36 , pp. 3008-3017
    • Wyman, T.B.1    Nicol, F.2    Zelphati, O.3    Sciara, P.V.4    Plank, C.5    Szoka F.C., Jr.6
  • 109
    • 0030843604 scopus 로고    scopus 로고
    • A novel gene delivery system using urothelial tissue engineered neo-organs
    • Yoo, J.J. and Attala, A. (1997) A novel gene delivery system using urothelial tissue engineered neo-organs. J. Urol., 158, 1066-1070.
    • (1997) J. Urol. , vol.158 , pp. 1066-1070
    • Yoo, J.J.1    Attala, A.2
  • 110
    • 0028498565 scopus 로고
    • Genetically engineered fluoropolymers. Synthesis of repetitive polypeptides containing p-fluorophenylalanine residues
    • Yoshikawa, E., Fournier, M.J., Mason, T.L. and Tirrell, D.A. (1994) Genetically engineered fluoropolymers. Synthesis of repetitive polypeptides containing p-fluorophenylalanine residues. Macromolecules, 27, 5471-5475.
    • (1994) Macromolecules , vol.27 , pp. 5471-5475
    • Yoshikawa, E.1    Fournier, M.J.2    Mason, T.L.3    Tirrell, D.A.4
  • 112
    • 0000934967 scopus 로고
    • Biological synthesis of monodisperse derivatives of poly(α,L-glutamic acid): Model rodlike peptides
    • Zhang, G., Fournier, M.J., Mason, T.L. and Tirrell, D.A. (1992) Biological synthesis of monodisperse derivatives of poly(α,L-glutamic acid): model rodlike peptides. Macromolecules, 25, 3601-3603.
    • (1992) Macromolecules , vol.25 , pp. 3601-3603
    • Zhang, G.1    Fournier, M.J.2    Mason, T.L.3    Tirrell, D.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.