Intrathecal coadministration of bupivacaine diminishes morphine dose progression during long-term intrathecal infusion in cancer patients

Clinical Journal of Pain

Volumn 15, Issue 3, 1999, Pages 166-172

  Van Dongen, Robert T M ^a   Crul, Ben J P ^a   Van Egmond, Jan ^a  

^a RADBOUD UNIVERSITY NIJMEGEN   (Netherlands)

Author keywords

Cancer pain; Continuous infusion; Intrathecal morphine and bupivacaine; Synergism; Tolerance

Indexed keywords

ANTICONVULSIVE AGENT; ANTIDEPRESSANT AGENT; BENZODIAZEPINE DERIVATIVE; BUPIVACAINE; BUPRENORPHINE; CORTICOSTEROID; MORPHINE; NONSTEROID ANTIINFLAMMATORY AGENT; PARACETAMOL;

ADULT; AGED; ANALGESIA; ANTINOCICEPTION; ARTICLE; CANCER GROWTH; CANCER PAIN; CLINICAL ARTICLE; CLINICAL TRIAL; CONTINUOUS INFUSION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFECT; DRUG EFFICACY; DRUG POTENTIATION; DRUG TOLERANCE; FEMALE; HUMAN; INTRATHECAL DRUG ADMINISTRATION; MALE; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL;

ADULT; AGED; AGED, 80 AND OVER; ANALGESICS, OPIOID; ANESTHETICS, LOCAL; BUPIVACAINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG COMBINATIONS; DRUG SYNERGISM; FEMALE; HUMANS; INJECTIONS, SPINAL; MALE; MIDDLE AGED; MORPHINE; NEOPLASMS; PALLIATIVE CARE; PROSPECTIVE STUDIES;

EID: 0032857888     PISSN: 07498047     EISSN: None     Source Type: Journal    
DOI: 10.1097/00002508-199909000-00002     Document Type: Article

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