New benzoquinolizin-5-one derivatives as furocoumarin analogs: DNA-interactions and molecular modeling studies

Farmaco

Volumn 54, Issue 8, 1999, Pages 551-561

  Miolo, Giorgia ^a   Moro, Stefano ^a   Vedaldi, Daniela ^a   Caffieri, Sergio ^a   Guiotto, Adriano ^a   Dall'Acqua, Francesco ^a  

^a UNIVERSITY OF PADOVA   (Italy)

Author keywords

Benzoquinolizinones; DNA intercalation; DNA photobinding; Furocoumarin analogs; Molecular modeling

Indexed keywords

10 ACETOXY 7 METHYL 3H,5H ENZO[IJ]QUINOLIZIN 5 ONE; 10 METHOXY 7 METHYL 1H,5H BENZO[IJ]QUINOLIZIN 5 ONE; 10 METHOXY 7 METHYL 3H,5H BENZO[IJ]QUINOLIZIN 5 ONE; BACTERIAL DNA; METHOXSALEN; QUINOLIZINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; COMPUTER ANALYSIS; DNA BINDING; DRUG STRUCTURE; FLUOROMETRY; IN VITRO STUDY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PHOTOREACTIVITY; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION; ULTRAVIOLET A RADIATION;

CIRCULAR DICHROISM; COUMARINS; CROSS-LINKING REAGENTS; DNA; DNA ADDUCTS; FLUOROMETRY; INTERCALATING AGENTS; KINETICS; MODELS, MOLECULAR; QUANTUM THEORY; QUINOLIZINES; ULTRAVIOLET RAYS;

EID: 0032857465     PISSN: 0014827X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-827X(99)00062-2     Document Type: Article

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