A method for estimating and testing area under the curve in serial sacrifice, batch, and complete data designs

Journal of Biopharmaceutical Statistics

Volumn 9, Issue 3, 1999, Pages 451-464

  Holder, D J ^a   Hsuan, F ^a   Dixit, R ^a   Soper, K ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

AUC; Dose proportionality; Dose trend; Serial sacrifice; Toxicokinetics

Indexed keywords

TOXIN;

ANALYTIC METHOD; ANALYTICAL ERROR; ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; FEMALE; INTERMETHOD COMPARISON; NONHUMAN; PREDICTION; PRIORITY JOURNAL; RAT; STATISTICAL MODEL; TOXICOKINETICS; VALIDATION PROCESS; VARIANCE;

ANALYSIS OF VARIANCE; ANIMALS; AREA UNDER CURVE; BIOMETRY; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; LINEAR MODELS; MATHEMATICAL COMPUTING; PREGNANCY; RATS; RESEARCH DESIGN; TOXICOLOGY;

EID: 0032856847     PISSN: 10543406     EISSN: None     Source Type: Journal    
DOI: 10.1081/BIP-100101187     Document Type: Article

References (14)