Comparison of the expression of fibrosis-associated genes in glomeruli after renal transplantation between conventional cadaveric and non-heart-beating donors

British Journal of Surgery

Volumn 86, Issue 10, 1999, Pages 1264-1268

  Jain, S ^a   Bicknell, G R ^a   White, S A ^a   Williams, S T ^a   Furness, P N ^a   Nicholson, M L ^a  

^a LEICESTER GENERAL HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; TISSUE INHIBITOR OF METALLOPROTEINASE 1;

ADULT; ARTICLE; CADAVER DONOR; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; EXTRACELLULAR MATRIX; FEMALE; GENE EXPRESSION; GLOMERULUS; HUMAN; KIDNEY FIBROSIS; KIDNEY FUNCTION; KIDNEY ISCHEMIA; KIDNEY TRANSPLANTATION; MALE; NEEDLE BIOPSY; ORGAN DONOR; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADULT; BIOPSY; CADAVER; FEMALE; FIBROSIS; GENE EXPRESSION; HUMANS; KIDNEY DISEASES; KIDNEY GLOMERULUS; KIDNEY TRANSPLANTATION; LIVING DONORS; MALE; MIDDLE AGED; RNA, MESSENGER; TISSUE DONORS; TISSUE INHIBITOR OF METALLOPROTEINASE-1; TRANSFORMING GROWTH FACTOR BETA;

EID: 0032855977     PISSN: 00071323     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2168.1999.01240.x     Document Type: Article

References (14)

1. Royal College of Surgeons of England. The Report of the Working Party to Review Organ Transplantation. London: Royal College of Surgeons of England, 1999.
2. Paul LC. Chronic renal transplant loss. Kidney Int 1995; 47: 1491-9.
3. Bicknell GR, Shaw JA, Pringle JH, Furness PN. Amplification of specific mRNA from a single human renal glomerulus, with an approach to the separation of epithelial cell mRNA. J Pathol 1996; 180: 188-93.
4. Hall LL, Bicknell GR, Primrose L, Pringle JH, Shaw JA, Furness PN. Reproducibility in the quantification of mRNA levels by RT-PCR-ELISA and RT competitive-PCR-ELISA. Biotechniques 1998; 24: 652-8.
5. Murphy G, Docherty AJ. The matrix metalloproteinases and their inhibitors. Am J Resp Cell Mol Biol 1992; 7: 120-5.
6. Kikuchi K, Kadono T, Furue M, Tamaki K. Tissue inhibitor of metalloproteinase 1 (TIMP-1) may be an autocrine growth factor in scleroderma fibroblasts. J Invest Dermatol 1997; 108: 281-4.
7. Border WA, Noble NA. Transforming growth factor beta in tissue fibrosis. N Engl J Med 1994; 331: 1286-92.
8. Brenchley PE, Short CD, Roberts IS. Is persistent TGF betal expression the mechanism responsible for chronic renal allograft loss? Nephrol Dial Transplant 1998; 13: 548-51 (Editorial).
9. Ko YJ, Sugar L, Zaltzman J, Paul LC. Alpha-smooth muscle actin and collagen deposition in dysfunctional renal transplants. Transplantation 1997; 63: 156-8.
10. Gould VE, Martinez-Lacabe V, Virtanen I, Sahlin KM, Schwartz MM. Differential distribution of tenascin and cellular fibronectins in acute and chronic renal allograft rejection. Lab Invest 1992; 67: 71-9.
11. Nicholson ML, Bailey E, Williams S, Harris KP, Furness PN. Renal allograft survival can be predicted by histomorphometric assessment of extracellular matrix in 6-month protocol biopsies. Transplant Proc 1998; 30: 1305-6.
12. Cho YW, Terasaki PI, Cecka JM, Gjertson DW. Transplantation of kidneys from donors whose hearts have stopped beating. N Engl J Med 1998; 338: 221-5.
13. Wijnen RM, Booster MH, Stubenitsky BM, de Boer J, Heineman E, Kootstra G. Outcome of transplantation of non-heart-beating donor kidneys. Lancet 1995; 345: 1067-70.
14. Tanabe K, Oshima T, Tokumoto T, Ishikawa N, Kanematsu A, Shinmura H et al. Long-term renal function in non-heart-beating donor kidney transplantation: a single-center experience. Transplantation 1998; 66: 1708-13.