In vitro immunization with a recombinant antigen carrying the HIV-1 RT248-262 determinant inserted at different locations results in altered TCRVB region usage

Human Immunology

Volumn 60, Issue 9, 1999, Pages 755-763

  Prisco, Antonella ^b   Bonomi, Giovanna ^a   Moschella, Federica ^a   Ombra, Maria Neve ^a   De Berardinis, Piergiuseppe ^b   Guardiola, John ^a  

^a INSTITUTE OF GENETICS AND BIOPHYSICS ADRIANO BUZZATI TRAVERSO   (Italy)

^b Inst Protein Biochem and Enzymol   (Italy)

Author keywords

Flanking residues; Immunodominance; Recombinant antigens; RT peptides; TCRVB usage

Indexed keywords

HUMAN IMMUNODEFICIENCY VIRUS ANTIGEN; RECOMBINANT PROTEIN; RNA DIRECTED DNA POLYMERASE; SYNTHETIC PEPTIDE;

AMINO TERMINAL SEQUENCE; ANTIGEN PRESENTING CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; GENE INSERTION; GENE LOCATION; HUMAN; HUMAN CELL; IMMUNIZATION; IMMUNOGENICITY; MAJOR HISTOCOMPATIBILITY COMPLEX; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION; T LYMPHOCYTE SUBPOPULATION;

AMINO ACID SEQUENCE; CELL LINE; HIV ANTIGENS; HIV-1; HIV-1 REVERSE TRANSCRIPTASE; HUMANS; MOLECULAR SEQUENCE DATA; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; RECOMBINANT FUSION PROTEINS;

EID: 0032854420     PISSN: 01988859     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0198-8859(99)00055-5     Document Type: Article

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