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Volumn 42, Issue 2-3, 1999, Pages 117-124

DNA vaccines

Author keywords

Genetic immunization; Hepatitis B virus; Hepatitis C virus

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; DNA VACCINE; STRUCTURAL PROTEIN; VIRUS VACCINE;

EID: 0032854018     PISSN: 03005526     EISSN: None     Source Type: Journal    
DOI: 10.1159/000024971     Document Type: Review
Times cited : (45)

References (78)
  • 1
    • 0000131547 scopus 로고
    • Epidemiology of hepatitis B virus infection
    • Ellis RW (ed): New York, Dekker
    • Hadler SC, Margolis HS: Epidemiology of hepatitis B virus infection; in Ellis RW (ed): Hepatitis B Vaccines in Clinical Practice. New York, Dekker, 1993, pp 323-336.
    • (1993) Hepatitis B Vaccines in Clinical Practice , pp. 323-336
    • Hadler, S.C.1    Margolis, H.S.2
  • 2
    • 0024509701 scopus 로고
    • Isolation of a cDNA clone derived from a blood-home non-A, non-B viral hepatitis genome
    • Choo QL, Kuo G, Weiner AJ, Overby LR, Bradley DW, Houghton M: Isolation of a cDNA clone derived from a blood-home non-A, non-B viral hepatitis genome. Science 1989; 244:359-362.
    • (1989) Science , vol.244 , pp. 359-362
    • Choo, Q.L.1    Kuo, G.2    Weiner, A.J.3    Overby, L.R.4    Bradley, D.W.5    Houghton, M.6
  • 4
    • 0030752667 scopus 로고    scopus 로고
    • Hepatitis C virus: Epidemiology and transmission
    • Heintges T, Wands JR: Hepatitis C virus: Epidemiology and transmission. Hepatology 1997; 26:521-526.
    • (1997) Hepatology , vol.26 , pp. 521-526
    • Heintges, T.1    Wands, J.R.2
  • 5
    • 0031021442 scopus 로고    scopus 로고
    • Vaccines to prevent viral hepatitis
    • Lemon SM, Thomas DL: Vaccines to prevent viral hepatitis. N Engl J Med 1997;336:196-204.
    • (1997) N Engl J Med , vol.336 , pp. 196-204
    • Lemon, S.M.1    Thomas, D.L.2
  • 6
    • 1842291578 scopus 로고    scopus 로고
    • The treatment of chronic viral hepatitis
    • Hoofnagle JH, Di Bisceglie AM: The treatment of chronic viral hepatitis. N Engl J Med 1997; 336:347-356.
    • (1997) N Engl J Med , vol.336 , pp. 347-356
    • Hoofnagle, J.H.1    Di Bisceglie, A.M.2
  • 7
    • 0345416844 scopus 로고    scopus 로고
    • Therapy of hepatitis C: Meta-analysis of interferon alfa-2b trials
    • Carithers RL Jr, Emerson SS: Therapy of hepatitis C: Meta-analysis of interferon alfa-2b trials. Hepatology 1997;26:83S-88S.
    • (1997) Hepatology , vol.26
    • Carithers R.L., Jr.1    Emerson, S.S.2
  • 11
    • 0030668566 scopus 로고    scopus 로고
    • Gene vaccination for hepatitis C
    • Inchauspe G: Gene vaccination for hepatitis C. Springer Semin Immunopathol 1997;19:211-221.
    • (1997) Springer Semin Immunopathol , vol.19 , pp. 211-221
    • Inchauspe, G.1
  • 12
    • 0030915527 scopus 로고    scopus 로고
    • DNA vaccines and viral hepatitis: Are we going around in circles?
    • Koziel MJ, Liang TJ: DNA vaccines and viral hepatitis: Are we going around in circles? [editorial: comment] [see comments]. Gastroenterology 1997;112:1410-1414.
    • (1997) Gastroenterology , vol.112 , pp. 1410-1414
    • Koziel, M.J.1    Liang, T.J.2
  • 16
    • 0030718471 scopus 로고    scopus 로고
    • Plasmid DNA vaccination: Mechanism of antigen presentation
    • Corr M, Tighe H: Plasmid DNA vaccination: Mechanism of antigen presentation. Springer Semin Immunopathol 1997;19:139-145.
    • (1997) Springer Semin Immunopathol , vol.19 , pp. 139-145
    • Corr, M.1    Tighe, H.2
  • 18
    • 0029553983 scopus 로고
    • Use of plasmid DNA for direct gene transfer and immunization
    • Davis HL, Michel ML, Whalen RG: Use of plasmid DNA for direct gene transfer and immunization. Ann NY Acad Sci 1995;772:21-29.
    • (1995) Ann NY Acad Sci , vol.772 , pp. 21-29
    • Davis, H.L.1    Michel, M.L.2    Whalen, R.G.3
  • 19
    • 0032077066 scopus 로고    scopus 로고
    • Routes of plasmid DNA vaccination that prime murine humoral and cellular immune responses
    • Bohm W, Mertens T, Schirmbeck R, Reinmann J: Routes of plasmid DNA vaccination that prime murine humoral and cellular immune responses. Vaccine 1998;16:949-954.
    • (1998) Vaccine , vol.16 , pp. 949-954
    • Bohm, W.1    Mertens, T.2    Schirmbeck, R.3    Reinmann, J.4
  • 20
    • 7144256527 scopus 로고    scopus 로고
    • Immune response to a hepatitis B DNA vaccine in aotus monkeys: A comparison of vaccine formulation, route, and method of administration
    • Gramzinski RA, Millan CL, Obaldia N, Hoffman SL, Davis HL: Immune response to a hepatitis B DNA vaccine in Aotus monkeys: A comparison of vaccine formulation, route, and method of administration. Mol Med 1998;4: 109-118.
    • (1998) Mol Med , vol.4 , pp. 109-118
    • Gramzinski, R.A.1    Millan, C.L.2    Obaldia, N.3    Hoffman, S.L.4    Davis, H.L.5
  • 22
    • 0342973212 scopus 로고    scopus 로고
    • DNA vector constructs that prime hepatitis B surface antigen-specific cytotoxic T lymphocyte and antibody responses in mice after intramuscular injection
    • Bohm W, Kuhrober A, Paier T, Mertens T, Reimann J, Schirmbeck R: DNA vector constructs that prime hepatitis B surface antigen-specific cytotoxic T lymphocyte and antibody responses in mice after intramuscular injection. J Immunol Methods 1996;193:29-40.
    • (1996) J Immunol Methods , vol.193 , pp. 29-40
    • Bohm, W.1    Kuhrober, A.2    Paier, T.3    Mertens, T.4    Reimann, J.5    Schirmbeck, R.6
  • 23
    • 0030063276 scopus 로고    scopus 로고
    • DNA-based immunization against the envelope proteins of the hepatitis B virus
    • Mancini M, Davis H, Tiollais P, Michel ML: DNA-based immunization against the envelope proteins of the hepatitis B virus. J Biotechnol 1996;44:47-57.
    • (1996) J Biotechnol , vol.44 , pp. 47-57
    • Mancini, M.1    Davis, H.2    Tiollais, P.3    Michel, M.L.4
  • 24
    • 0031066827 scopus 로고    scopus 로고
    • Enhancement of cellular and humoral immune responses to hepatitis C virus core protein using DNA-based vaccines augmented with cytokine-expressing plasmids
    • Geissler M, Gesien A, Tokushige K, Wands JR: Enhancement of cellular and humoral immune responses to hepatitis C virus core protein using DNA-based vaccines augmented with cytokine-expressing plasmids. J Immunol 1997; 158:1231-1237.
    • (1997) J Immunol , vol.158 , pp. 1231-1237
    • Geissler, M.1    Gesien, A.2    Tokushige, K.3    Wands, J.R.4
  • 25
    • 0031808286 scopus 로고    scopus 로고
    • Cytokine and hepatitis B virus DNA co-immunizations enhance cellular and humoral immune responses to the middle but not to the large hepatitis B virus surface antigen in mice
    • Geissler M, Schirmbeck R, Reimann J, Blum HE, Wands JR: Cytokine and hepatitis B virus DNA co-immunizations enhance cellular and humoral immune responses to the middle but not to the large hepatitis B virus surface antigen in mice. Hepatology 1998;28:202-210.
    • (1998) Hepatology , vol.28 , pp. 202-210
    • Geissler, M.1    Schirmbeck, R.2    Reimann, J.3    Blum, H.E.4    Wands, J.R.5
  • 26
    • 0031060327 scopus 로고    scopus 로고
    • Improvement of hepatitis B virus DNA vaccines by plasmids coexpressing hepatitis B surface antigen and interleukin-2
    • Chow YH, Huang WL, Chi WK, Chu YD, Tao MH: Improvement of hepatitis B virus DNA vaccines by plasmids coexpressing hepatitis B surface antigen and interleukin-2. J Virol 1997; 71:169-178.
    • (1997) J Virol , vol.71 , pp. 169-178
    • Chow, Y.H.1    Huang, W.L.2    Chi, W.K.3    Chu, Y.D.4    Tao, M.H.5
  • 27
    • 0031953116 scopus 로고    scopus 로고
    • Development of Th1 and Th2 populations and the nature of immune response to hepatitis B virus DNA vaccines can be modulated by codelivery of various cytokine genes
    • Chow YH, Chiang BL, Lee YL, Chi WK, Lin WC, Chen YT, Tao MH: Development of Th1 and Th2 populations and the nature of immune response to hepatitis B virus DNA vaccines can be modulated by codelivery of various cytokine genes. J Immunol 1998;160:1320-1329.
    • (1998) J Immunol , vol.160 , pp. 1320-1329
    • Chow, Y.H.1    Chiang, B.L.2    Lee, Y.L.3    Chi, W.K.4    Lin, W.C.5    Chen, Y.T.6    Tao, M.H.7
  • 28
    • 0028902839 scopus 로고
    • Manipulation of the immune response to a plasmid-encoded viral antigen by coinoculation with plasmids expressing cytokines
    • Xiang Z, Ertl HC: Manipulation of the immune response to a plasmid-encoded viral antigen by coinoculation with plasmids expressing cytokines. Immunity 1995;2:129-135.
    • (1995) Immunity , vol.2 , pp. 129-135
    • Xiang, Z.1    Ertl, H.C.2
  • 29
    • 0030723917 scopus 로고    scopus 로고
    • Introduction: Gene vaccination, current concepts and future directions
    • Raz E: Introduction: Gene vaccination, current concepts and future directions. Springer Semin Immunopathol 1997;19:131-137.
    • (1997) Springer Semin Immunopathol , vol.19 , pp. 131-137
    • Raz, E.1
  • 31
    • 0030755481 scopus 로고    scopus 로고
    • Enhancement of immunodeficiency virus-specific immune responses in DNA-immunized rhesus macaques
    • Fuller DH, Corb MM, Barnett S, Steimer K, Haynes JR: Enhancement of immunodeficiency virus-specific immune responses in DNA-immunized rhesus macaques. Vaccine 1997; 15:924-926.
    • (1997) Vaccine , vol.15 , pp. 924-926
    • Fuller, D.H.1    Corb, M.M.2    Barnett, S.3    Steimer, K.4    Haynes, J.R.5
  • 32
    • 0029549730 scopus 로고
    • Immune responses to hepatitis B virus surface and core antigens in mice, monkeys, and pigs after accell particle-mediated DNA immunization
    • Fuller JT, Fuller DH, McCabe D, Haynes JR, Widera G: Immune responses to hepatitis B virus surface and core antigens in mice, monkeys, and pigs after Accell particle-mediated DNA immunization. Ann NY Acad Sci 1995; 772:282-284.
    • (1995) Ann NY Acad Sci , vol.772 , pp. 282-284
    • Fuller, J.T.1    Fuller, D.H.2    McCabe, D.3    Haynes, J.R.4    Widera, G.5
  • 33
    • 0030757875 scopus 로고    scopus 로고
    • Genetic immunization: A new era in vaccines and immune therapeutics
    • Chattergoon M, Boyer J, Weiner DB: Genetic immunization: A new era in vaccines and immune therapeutics. FASEB J 1997;11:753-763.
    • (1997) FASEB J , vol.11 , pp. 753-763
    • Chattergoon, M.1    Boyer, J.2    Weiner, D.B.3
  • 37
    • 0029792293 scopus 로고    scopus 로고
    • Differential cytotoxic T-lymphocyte responsiveness to the hepatitis B and C viruses in chronically infected patients
    • Rehermann B, Chang KM, McHutchinson J, Kokka R, Houghton M, Rice CM, Chisari FV: Differential cytotoxic T-lymphocyte responsiveness to the hepatitis B and C viruses in chronically infected patients. J Virol 1996;70: 7092-7102.
    • (1996) J Virol , vol.70 , pp. 7092-7102
    • Rehermann, B.1    Chang, K.M.2    McHutchinson, J.3    Kokka, R.4    Houghton, M.5    Rice, C.M.6    Chisari, F.V.7
  • 38
    • 0030892283 scopus 로고    scopus 로고
    • Cytotoxic T cells and viral hepatitis
    • Chisari FV: Cytotoxic T cells and viral hepatitis. J Clin Invest 1997;99:1472-1477.
    • (1997) J Clin Invest , vol.99 , pp. 1472-1477
    • Chisari, F.V.1
  • 39
    • 0029051321 scopus 로고
    • DNA-mediated immunization to the hepatitis B surface antigen in mice: Aspects of the humoral response mimic hepatitis B viral infection in humans
    • Michel ML, Davis HL, Schleef M, Mancini M, Tiollais P, Whalen RG: DNA-mediated immunization to the hepatitis B surface antigen in mice: Aspects of the humoral response mimic hepatitis B viral infection in humans. Proc Natl Acad Sci USA 1995;92:5307-5311.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 5307-5311
    • Michel, M.L.1    Davis, H.L.2    Schleef, M.3    Mancini, M.4    Tiollais, P.5    Whalen, R.G.6
  • 40
    • 0028081659 scopus 로고
    • Direct gene transfer in skeletal muscle: Plasmid DNA-based immunization against the hepatitis B virus surface antigen
    • Davis HL, Michel ML, Mancini M, Schleef M, Whalen RG: Direct gene transfer in skeletal muscle: Plasmid DNA-based immunization against the hepatitis B virus surface antigen. Vaccine 1994;12:1503-1509.
    • (1994) Vaccine , vol.12 , pp. 1503-1509
    • Davis, H.L.1    Michel, M.L.2    Mancini, M.3    Schleef, M.4    Whalen, R.G.5
  • 41
    • 0028864849 scopus 로고
    • DNA-mediated immunization in mice induces a potent MHC class I-restricted cytotoxic T lymphocyte response to the hepatitis B envelope protein
    • Davis HL, Schirmbeck R, Reimann J, Whalen RG: DNA-mediated immunization in mice induces a potent MHC class I-restricted cytotoxic T lymphocyte response to the hepatitis B envelope protein. Hum Gene Ther 1995;6:1447-1456.
    • (1995) Hum Gene Ther , vol.6 , pp. 1447-1456
    • Davis, H.L.1    Schirmbeck, R.2    Reimann, J.3    Whalen, R.G.4
  • 42
    • 0030174678 scopus 로고    scopus 로고
    • DNA-mediated immunization to hepatitis B surface antigen: Longevity of primary response and effect of boost
    • Davis HL, Mancini M, Michel ML, Whalen RG: DNA-mediated immunization to hepatitis B surface antigen: Longevity of primary response and effect of boost. Vaccine 1996;14: 910-915.
    • (1996) Vaccine , vol.14 , pp. 910-915
    • Davis, H.L.1    Mancini, M.2    Michel, M.L.3    Whalen, R.G.4
  • 43
    • 0029550052 scopus 로고
    • DNA-mediated immunization to the hepatitis B surface antigen. Activation and entrainment of the immune response
    • Whalen RG, Leclerc C, Deriaud E, Schirmbeck R. Reimann J, Davis HL: DNA-mediated immunization to the hepatitis B surface antigen. Activation and entrainment of the immune response. Ann NY Acad Sci 1995;772:64-76.
    • (1995) Ann NY Acad Sci , vol.772 , pp. 64-76
    • Whalen, R.G.1    Leclerc, C.2    Deriaud, E.3    Schirmbeck, R.4    Reimann, J.5    Davis, H.L.6
  • 44
    • 0030904125 scopus 로고    scopus 로고
    • Cellular and humoral immune response to hepatitis B virus structural proteins in mice after DNA-based immunization
    • Geissler M, Tokushige K, Chante CC, Zurawski VR, Wands JR: Cellular and humoral immune response to hepatitis B virus structural proteins in mice after DNA-based immunization. Gastroenterology 1997;112:1307-1320.
    • (1997) Gastroenterology , vol.112 , pp. 1307-1320
    • Geissler, M.1    Tokushige, K.2    Chante, C.C.3    Zurawski, V.R.4    Wands, J.R.5
  • 45
    • 1842299314 scopus 로고    scopus 로고
    • Characterization of humoral and CD4+ cellular responses after genetic immunization with retroviral vectors expressing different forms of the hepatitis B virus core and e antigens
    • Sallherg M, Townsend K, Chen M, O'Dea J, Banks T, Jolly DJ, Chang SM, Lee WT, Milich DR: Characterization of humoral and CD4+ cellular responses after genetic immunization with retroviral vectors expressing different forms of the hepatitis B virus core and e antigens. J Virol 1997;71:5295-5303.
    • (1997) J Virol , vol.71 , pp. 5295-5303
    • Sallherg, M.1    Townsend, K.2    Chen, M.3    O'Dea, J.4    Banks, T.5    Jolly, D.J.6    Chang, S.M.7    Lee, W.T.8    Milich, D.R.9
  • 46
    • 0029084640 scopus 로고
    • DNA-based immunization with chimeric vectors for the induction of immune responses against the hepatitis C virus nucleocapsid
    • Major ME, Vitvitski L, Mink MA, Schleef M, Whalen RG, Trepo C, Inchauspe G: DNA-based immunization with chimeric vectors for the induction of immune responses against the hepatitis C virus nucleocapsid. J Virol 1995;69: 5798-5805.
    • (1995) J Virol , vol.69 , pp. 5798-5805
    • Major, M.E.1    Vitvitski, L.2    Mink, M.A.3    Schleef, M.4    Whalen, R.G.5    Trepo, C.6    Inchauspe, G.7
  • 47
    • 0029101242 scopus 로고
    • Nucleic acid vaccination primes hepatitis B virus surface antigen specific cytotoxic T lymphocytes in nonresponder mice
    • Schirmbeck R, Bohm W, Ando K, Chisari FV, Reimann J: Nucleic acid vaccination primes hepatitis B virus surface antigen specific cytotoxic T lymphocytes in nonresponder mice. J Virol 1995;69:5929-5934.
    • (1995) J Virol , vol.69 , pp. 5929-5934
    • Schirmbeck, R.1    Bohm, W.2    Ando, K.3    Chisari, F.V.4    Reimann, J.5
  • 48
    • 0030751906 scopus 로고    scopus 로고
    • DNA vaccination with plasmids encoding the intracellular (HBcAg) or secreted (HBeAg) form of the core protein of hepatitis B virus primes T cell responses to two overlapping Kb-and Kd-restricted epitopes
    • Kuhrober A, Wild J, Pudollek HP, Chisari FV, Reimann J: DNA vaccination with plasmids encoding the intracellular (HBcAg) or secreted (HBeAg) form of the core protein of hepatitis B virus primes T cell responses to two overlapping Kb-and Kd-restricted epitopes. Int Immunol 1997;9:1203-1212.
    • (1997) Int Immunol , vol.9 , pp. 1203-1212
    • Kuhrober, A.1    Wild, J.2    Pudollek, H.P.3    Chisari, F.V.4    Reimann, J.5
  • 50
    • 0027369829 scopus 로고
    • DNA-based immunization induces continuous secretion of hepatitis B surface antigen and high levels of circulating antibody
    • Davis HL, Michel ML, Whalen RG: DNA-based immunization induces continuous secretion of hepatitis B surface antigen and high levels of circulating antibody. Hum Mol Genet 1993;2:1847-1851.
    • (1993) Hum Mol Genet , vol.2 , pp. 1847-1851
    • Davis, H.L.1    Michel, M.L.2    Whalen, R.G.3
  • 51
    • 0031964257 scopus 로고    scopus 로고
    • CpG DNA is a potent enhancer of specific immunity in mice immunized with recombinant hepatitis b surface antigen
    • Davis HL, Weeranta R, Waldschmidt TJ, Tygrett L, Schorr J, Krieg AM: CpG DNA is a potent enhancer of specific immunity in mice immunized with recombinant hepatitis B surface antigen. J Immunol 1998;160:870-876.
    • (1998) J Immunol , vol.160 , pp. 870-876
    • Davis, H.L.1    Weeranta, R.2    Waldschmidt, T.J.3    Tygrett, L.4    Schorr, J.5    Krieg, A.M.6
  • 52
    • 0031215046 scopus 로고    scopus 로고
    • The preferential induction of a ThI immune response by DNA-based immunization is mediated by the immunostimulatory effect of plasmid DNA
    • Leclerc C, Deriaud E, Rojas M, Whalen RG: The preferential induction of a ThI immune response by DNA-based immunization is mediated by the immunostimulatory effect of plasmid DNA. Cell Immunol 1997;179:97-106.
    • (1997) Cell Immunol , vol.179 , pp. 97-106
    • Leclerc, C.1    Deriaud, E.2    Rojas, M.3    Whalen, R.G.4
  • 53
    • 0032209286 scopus 로고    scopus 로고
    • CpG DNA is a potent enhancer of systemic and mucosal immune response against hepatitis B surface antigen with intranasal administration to mice
    • McCluskie MJ, Davis HL: CpG DNA is a potent enhancer of systemic and mucosal immune response against hepatitis B surface antigen with intranasal administration to mice. J Immunol 1998;161:4463-4466.
    • (1998) J Immunol , vol.161 , pp. 4463-4466
    • McCluskie, M.J.1    Davis, H.L.2
  • 54
    • 0029985146 scopus 로고    scopus 로고
    • DNA-mediated immunization in a transgenic mouse model of the hepatitis B surface antigen chronic carrier state
    • Mancini M, Hadchouel M, Davis HL, Whalen RG, Tiollais P, Michel ML: DNA-mediated immunization in a transgenic mouse model of the hepatitis B surface antigen chronic carrier state. Proc Natl Acad Sci USA 1996;93:12496-12501.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 12496-12501
    • Mancini, M.1    Hadchouel, M.2    Davis, H.L.3    Whalen, R.G.4    Tiollais, P.5    Michel, M.L.6
  • 55
    • 0032211129 scopus 로고    scopus 로고
    • Dendritic cell immunization breaks cytotoxic T lymphocyte tolerance in hepatitis B virus transgenic mice
    • Shimizu Y, Guidotti LC, Fowler P, Chisari FV: Dendritic cell immunization breaks cytotoxic T lymphocyte tolerance in hepatitis B virus transgenic mice. J Immunol 1998;161:4520-4529.
    • (1998) J Immunol , vol.161 , pp. 4520-4529
    • Shimizu, Y.1    Guidotti, L.C.2    Fowler, P.3    Chisari, F.V.4
  • 56
    • 0031964789 scopus 로고    scopus 로고
    • Protective efficacy of DNA vaccines against duck hepatitis B virus infection
    • Triyatni M, Jilbert AR, Qiao M, Miller DS, Burrell CJ: Protective efficacy of DNA vaccines against duck hepatitis B virus infection. J Virol 1998;72:84-94.
    • (1998) J Virol , vol.72 , pp. 84-94
    • Triyatni, M.1    Jilbert, A.R.2    Qiao, M.3    Miller, D.S.4    Burrell, C.J.5
  • 58
    • 0029982850 scopus 로고    scopus 로고
    • DNA vaccine for hepatitis B: Evidence for immunogenicity in chimpanzees and comparison with other vaccines
    • Davis HL, McCluskie MJ, Gerin JL, Purcell RH: DNA vaccine for hepatitis B: Evidence for immunogenicity in chimpanzees and comparison with other vaccines. Proc Natl Acad Sci USA 1996;93:7213-7218.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 7213-7218
    • Davis, H.L.1    McCluskie, M.J.2    Gerin, J.L.3    Purcell, R.H.4
  • 59
    • 0030752483 scopus 로고    scopus 로고
    • Successful nucleic acid based immunization of newborn chimpanzees against hepatitis B virus
    • Prince AM, Whalen R, Brotman B: Successful nucleic acid based immunization of newborn chimpanzees against hepatitis B virus. Vaccine 1997;15:916-919.
    • (1997) Vaccine , vol.15 , pp. 916-919
    • Prince, A.M.1    Whalen, R.2    Brotman, B.3
  • 61
    • 0029778817 scopus 로고    scopus 로고
    • Quantitative analysis of the peripheral blood cytotoxic T lymphocyte response in patients with chronic hepatitis C virus infection
    • Rehermann B, Chang KM, McHutchison JG, Kokka R, Houghton M, Chisari FV: Quantitative analysis of the peripheral blood cytotoxic T lymphocyte response in patients with chronic hepatitis C virus infection. J Clin Invest 1996; 98:1432-1440.
    • (1996) J Clin Invest , vol.98 , pp. 1432-1440
    • Rehermann, B.1    Chang, K.M.2    McHutchison, J.G.3    Kokka, R.4    Houghton, M.5    Chisari, F.V.6
  • 62
    • 0029151623 scopus 로고
    • Possible mechanism involving T-lymphocyte response to nonstructural protein 3 in viral clearance in acute hepatitis C virus infection
    • Diepolder HM, Zachoval R, Hoffmann RM, Wierenga EA, Santantonio T, Jung MC, Eichenlaub D, Pape GR: Possible mechanism involving T-lymphocyte response to nonstructural protein 3 in viral clearance in acute hepatitis C virus infection. Lancet 1995;346:1006-1007.
    • (1995) Lancet , vol.346 , pp. 1006-1007
    • Diepolder, H.M.1    Zachoval, R.2    Hoffmann, R.M.3    Wierenga, E.A.4    Santantonio, T.5    Jung, M.C.6    Eichenlaub, D.7    Pape, G.R.8
  • 63
    • 10244225383 scopus 로고    scopus 로고
    • Different clinical behaviors of acute hepatitis C virus infection are associated with different vigor of the anti-viral cell-mediated immune response
    • Misaale G, Bertoni R, Lamonaca V, Valli A, Massari M, Mori C, Rumi MG, Houghton M, Fiaccadori F, Ferrari C: Different clinical behaviors of acute hepatitis C virus infection are associated with different vigor of the anti-viral cell-mediated immune response. J Clin Invest 1996;98:706-714.
    • (1996) J Clin Invest , vol.98 , pp. 706-714
    • Misaale, G.1    Bertoni, R.2    Lamonaca, V.3    Valli, A.4    Massari, M.5    Mori, C.6    Rumi, M.G.7    Houghton, M.8    Fiaccadori, F.9    Ferrari, C.10
  • 64
    • 0029156764 scopus 로고
    • Immune responses to plasmid DNA encoding the hepatitis C virus core protein
    • Lagging LM, Meyer K, Hoft D, Houghton M, Belshe RB, Ray R: Immune responses to plasmid DNA encoding the hepatitis C virus core protein. J Virol 1995;69:5859-5863.
    • (1995) J Virol , vol.69 , pp. 5859-5863
    • Lagging, L.M.1    Meyer, K.2    Hoft, D.3    Houghton, M.4    Belshe, R.B.5    Ray, R.6
  • 67
    • 0031050444 scopus 로고    scopus 로고
    • Plasmid DNA expressing a secreted or a nonsecreted form of hepatitis C virus nucleocapsid: Comparative studies of antibody and T-helper responses following genetic immunization
    • Inchauspe G, Vitvitski L, Major ME, Jung G, Spengler U, Maisonnas M, Trepo C: Plasmid DNA expressing a secreted or a nonsecreted form of hepatitis C virus nucleocapsid: Comparative studies of antibody and T-helper responses following genetic immunization. DNA Cell Biol 1997;16:185-195.
    • (1997) DNA Cell Biol , vol.16 , pp. 185-195
    • Inchauspe, G.1    Vitvitski, L.2    Major, M.E.3    Jung, G.4    Spengler, U.5    Maisonnas, M.6    Trepo, C.7
  • 68
    • 0030741985 scopus 로고    scopus 로고
    • DNA vaccination for the induction of immune responses against hepatitis C virus proteins
    • Inchauspe G, Major ME, Nakano I, Vitvitski L, Trepo C: DNA vaccination for the induction of immune responses against hepatitis C virus proteins. Vaccine 1997;15:853-856.
    • (1997) Vaccine , vol.15 , pp. 853-856
    • Inchauspe, G.1    Major, M.E.2    Nakano, I.3    Vitvitski, L.4    Trepo, C.5
  • 69
    • 0031573081 scopus 로고    scopus 로고
    • Inhibitory effects of chronic ethanol consumption on cellular immune responses to hepatitis C virus core protein are reversed by genetic immunizations augmented with cytokine-expressing plasmids
    • Geissler M, Gesien A, Wands JR: Inhibitory effects of chronic ethanol consumption on cellular immune responses to hepatitis C virus core protein are reversed by genetic immunizations augmented with cytokine-expressing plasmids. J Immunol 1997;159:5107-5113.
    • (1997) J Immunol , vol.159 , pp. 5107-5113
    • Geissler, M.1    Gesien, A.2    Wands, J.R.3
  • 70
    • 0028140138 scopus 로고
    • Neutralizing antibodies against hepatitis C virus and the emergence of neutralization escape mutant viruses
    • Shimizu YK, Hijikata M, Iwamoto A, Alter HJ, Purcell RH, Yoshikura H: Neutralizing antibodies against hepatitis C virus and the emergence of neutralization escape mutant viruses. J Virol 1994;68:1494-1500.
    • (1994) J Virol , vol.68 , pp. 1494-1500
    • Shimizu, Y.K.1    Hijikata, M.2    Iwamoto, A.3    Alter, H.J.4    Purcell, R.H.5    Yoshikura, H.6
  • 71
    • 0030817934 scopus 로고    scopus 로고
    • Immunization with plasmid DNA encoding hepatitis C virus envelope E2 antigenic domains induces antibodies whose immune reactivity is linked to the injection mode
    • Nakano I, Maertens G, Major ME, Vitvitski L, Dubuisson J, Fournillier A, De Martynoff G, Trepo C, Inchauspe G: Immunization with plasmid DNA encoding hepatitis C virus envelope E2 antigenic domains induces antibodies whose immune reactivity is linked to the injection mode. J Virol 1997;71:7101-7109.
    • (1997) J Virol , vol.71 , pp. 7101-7109
    • Nakano, I.1    Maertens, G.2    Major, M.E.3    Vitvitski, L.4    Dubuisson, J.5    Fournillier, A.6    De Martynoff, G.7    Trepo, C.8    Inchauspe, G.9
  • 72
    • 0031022661 scopus 로고    scopus 로고
    • A specific antibody response to HCV E2 elicited in mice by intramuscular inoculation of plasmid DNA containing coding sequences for E2
    • Tedeschi V, Akatsuka T, Shin JW, Battegay M, Feinstone SM: A specific antibody response to HCV E2 elicited in mice by intramuscular inoculation of plasmid DNA containing coding sequences for E2. Hepatology 1997;25:459-462.
    • (1997) Hepatology , vol.25 , pp. 459-462
    • Tedeschi, V.1    Akatsuka, T.2    Shin, J.W.3    Battegay, M.4    Feinstone, S.M.5
  • 73
    • 0032212215 scopus 로고    scopus 로고
    • Genetic immunization generates cellular and humoral immune responses against the non-structural proteins of the hepatitis C virus in a murine model
    • Encke J, zu Putlitz J, Geissler M, Wands JR: Genetic immunization generates cellular and humoral immune responses against the non-structural proteins of the hepatitis C virus in a murine model. J Immunol 1998;161:4917-4923.
    • (1998) J Immunol , vol.161 , pp. 4917-4923
    • Encke, J.1    Zu Putlitz, J.2    Geissler, M.3    Wands, J.R.4
  • 74
    • 0029819376 scopus 로고    scopus 로고
    • Chimaera and its modern virus-like descendants
    • Ulrich R, Gerlich WH, Kruger DH: Chimaera and its modern virus-like descendants. Intervirology 1996;39:126-132.
    • (1996) Intervirology , vol.39 , pp. 126-132
    • Ulrich, R.1    Gerlich, W.H.2    Kruger, D.H.3
  • 75
    • 0032077308 scopus 로고    scopus 로고
    • Differential cellular and humoral immune responses to HCV core and HBV envelope proteins after genetic immunizations using chimcric constructs
    • Geissler M, Tokushige K, Wakita T, Zurawski VR, Wands JR: Differential cellular and humoral immune responses to HCV core and HBV envelope proteins after genetic immunizations using chimcric constructs. Vaccine 1998;16:857-867.
    • (1998) Vaccine , vol.16 , pp. 857-867
    • Geissler, M.1    Tokushige, K.2    Wakita, T.3    Zurawski, V.R.4    Wands, J.R.5
  • 76
    • 0032518355 scopus 로고    scopus 로고
    • In vivo induction of specific cytotoxic T lymphocytes in mice and rhesus macaques immunized with DNA vector encoding an HIV epitope fused with hepatitis B surface antigen
    • Le Borgne S, Mancini M, Le Grand R, Schleef M, Dormont D, Tiollais P, Riviere Y, Michel ML: In vivo induction of specific cytotoxic T lymphocytes in mice and rhesus macaques immunized with DNA vector encoding an HIV epitope fused with hepatitis B surface antigen. Virology 1998;240:304-315.
    • (1998) Virology , vol.240 , pp. 304-315
    • Le Borgne, S.1    Mancini, M.2    Le Grand, R.3    Schleef, M.4    Dormont, D.5    Tiollais, P.6    Riviere, Y.7    Michel, M.L.8
  • 77
    • 0031006608 scopus 로고    scopus 로고
    • DNA inoculation with a plasmid vector carrying the hepatitis E virus structural protein gene induces immune response in mice
    • He J, Hoffman SL, Hayes CG: DNA inoculation with a plasmid vector carrying the hepatitis E virus structural protein gene induces immune response in mice. Vaccine 1997;15:357-362.
    • (1997) Vaccine , vol.15 , pp. 357-362
    • He, J.1    Hoffman, S.L.2    Hayes, C.G.3
  • 78
    • 0030483553 scopus 로고    scopus 로고
    • A preliminary study on immune response to hepatitis E virus DNA vaccine in mice
    • Lu F, Zhuang H, Zhu Y, Zhu X: A preliminary study on immune response to hepatitis E virus DNA vaccine in mice. Chin Med J (Engl) 1996; 109:919-921.
    • (1996) Chin Med J (Engl) , vol.109 , pp. 919-921
    • Lu, F.1    Zhuang, H.2    Zhu, Y.3    Zhu, X.4


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