Determination of 4-hydroxyifosfamide concomitantly with ifosfamide and its dechloroethylated metabolites using gas chromatography and a nitrogen phosphorus-selective detector

Journal of Chromatography B: Biomedical Sciences and Applications

Volumn 732, Issue 1, 1999, Pages 3-15

  Gourmel, Bernard ^a   Granvil, Camille P ^b   Denis, Sébastien L ^a   Wainer, Irving W ^c   Bousquet, Bernard ^a  

^a SAINT LOUIS HOSPITAL   (France)

^b UNIVERSITÉ DE MONTRÉAL   (Canada)

^c MCGILL UNIVERSITY   (Canada)

Author keywords

4 Hydroxyifosfamide; Ifosfamide

Indexed keywords

2 DECHLOROETHYLIFOSFAMIDE; 3 DECHLOROETHYLIFOSFAMIDE; 4 HYDROXYIFOSFAMIDE; CHLOROFORM; DRUG METABOLITE; IFOSFAMIDE; ISOPHOSPHORAMIDE MUSTARD; NITROGEN; PHOSPHORUS; REAGENT; TROFOSFAMIDE; UNCLASSIFIED DRUG;

ACCURACY; ADULT; ANALYTIC METHOD; ARTICLE; CAPILLARY; CHILD; CONTINUOUS INFUSION; CONTROLLED STUDY; DRUG BLOOD LEVEL; GAS CHROMATOGRAPHY; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; MASS SPECTROMETRY; PRIORITY JOURNAL; STANDARD;

ANTINEOPLASTIC AGENTS, ALKYLATING; CHROMATOGRAPHY, GAS; HUMANS; IFOSFAMIDE; MASS SPECTROMETRY; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY;

EID: 0032853106     PISSN: 13872273     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4347(99)00254-6     Document Type: Article

References (14)

1. Colvin M. Semin. Oncol. 9:1982;2.
2. Brade W.P., Herdrich K., Varini M. Cancer Treatment Rev. 12:1985;1-47.
3. Sladek N.E. Pharmacol Ther. 37:1988;301-355.
4. Hill D.L. Jr., Laster W.F., Kirk M.C. Cancer Res. 3:1973;1016-1022.
5. Walker D., Flinois J.P., Monkman S.C., Beloc C., Boddy A.V., Cholerton S., Daly A.K., Lind M.J., Pearson A.D.J., Beaune P.H., Idle J.R. Biochem. Pharmacol. 47:1994;1157-1161.
6. C.P. Granvil, J. Ducharme, A. Madan, U. Sanzgiri, M. Sharkawi, A. Parkinson, I.W. Wainer, 7th North American ISSX Meeting, San Diego, CA, October 1996.
7. Wainer I.W., Ducharme J., Granvil C.P., Trudeau M., Leyland-Jones B. Lancet. 383:1994;982-983.
8. Goren M.P., Wright R.K., Pratt C.B., Pell P.E. Lancet. 2:1986;1219.
9. Kaijser G.P., Korst A., Beijnen J.H., Bult A., Underberg W.J.M. Anticancer Res. 13:1993;1311-1324.
10. Anderson L.W., Luderman S.M., Colvin O.M., Grochow L.B., Strong J.M. J. Chromatogr. B. 667:1995;247-257.
11. Granvil C.P., Gerhke B., König W.A., Wainer I.W. J. Chromatogr. 622:1993;21-31.
12. Kaijser G.P., Biejnen J.H., Bult A., Wiese G., de Kraker J., Underberg W.J.M. J. Chromatogr. 571:1991;121-131.
13. Thala M.R.Z., Rogers H.J. J. Chromatogr. 311:1984;194-201.
14. B. Gourmel, N. Delepine, S. Denis, B. Bousquet, G. Delepine. ASCO Proceedings, Los Angeles, CA, 16-19 May 1998.