Multiplex PCR for the detection of Mycoplasma fermentans, M. hominis, and M. penetrans in patients with chronic fatigue syndrome, fibromyalgia, rheumatoid arthritis, and Gulf War Syndrome

Journal of Chronic Fatigue Syndrome

Volumn 5, Issue 3-4, 1999, Pages 187-197

  Vojdani, Aristo ^a,b,d   Franco, Al Robert ^c  

^a California   (United States)

^b CHARLES R DREW UNIVERSITY OF MEDICINE AND SCIENCE   (United States)

^c Arthritis Center of Riverside   (United States)

^d NONE   (United States)

Author keywords

And chronic fatigue syndrome; And gulf war syndrome; Fibromyalgia; M. hominis; M. penetrans; Multiplex polymerase chain reaction (PCR); Mycoplasma fermentans; Rheumatoid arthritis

Indexed keywords

ARTICLE; CHRONIC FATIGUE SYNDROME; DISEASE ASSOCIATION; DNA DETERMINATION; FIBROMYALGIA; MYCOPLASMA; MYCOPLASMA HOMINIS; PATHOGENICITY; PERSIAN GULF SYNDROME; POLYMERASE CHAIN REACTION; RHEUMATOID ARTHRITIS;

EID: 0032852570     PISSN: 10573321     EISSN: None     Source Type: Journal    
DOI: 10.1300/J092v05n03_16     Document Type: Article

References (25)

1. Grau, O., Kovacic, R., Griffais, R., et al. Development of PCR-based assays for the detection of two human mollicute species, Mycoplasma penetrans and M. hominis. Molecular and Cellular Probes 1994; 8:139-148.
2. Baseman, J.B., and Tully, J.G. Mycoplasmas: Sophisticated, reemerging, and burdened by their notoriety. Emerging Infectious Diseases 1997; 3: 21-32.
3. Vojdani, A., Choppa, P.C., Tagle, C., et al. Detection of Mycoplasma genus and Mycoplasma fermentans by PCR in patients with chronic fatigue syndrome. FEMS 1998. (in press)
4. Schaeverbeke, T., Renaudin, H., Clerc, M., et al. Systematic detection of mycoplasmas by culture and polymerase chain reaction (PCR) in 209 synovial fluid samples. British Journal of Rheumatology 1997; 36: 310-314.
5. Nicolson, G.L., and Nicolson, N.L. Diagnosis and treatment of Mycoplasmal infections in Persian Gulf War Illness-CFIDS Patients. Intl Journal of Occupational Medicine, Immunology, and Toxicology 1996; 5(1): 69-78.
6. Buchwald, D. and Garrity, D. Comparison of patients with chronic fatigue syndrome, fibromyalgia, and multiple chemical sensitivities. Arch Intern Med 1994; 154: 2049-2053.
7. Ziem, G. and Done, A. Chronic fatigue, fibromyalgia, and chemical sensitivity: overlapping disorders. Arch Intern Med 1995; 154: 1913.
8. Nicolson, G.L. Chronic infections as a common etiology for many patients with chronic fatigue syndrome, fibromyalgia, and Gulf War Illness. Intern J Med 1998; 1: 42-46.
9. Kavanaugh, A.F. and Lipsky, P.E. Rheumatoid Arthritis. In Clinical Immunology Principles and Practice. St. Louis: Mosby-Year Book, Inc., 1996. pp. 1093-1116.
10. Kenny, G.E., and Foy H.M. Mycoplasmal infection. In Clinical Diagnosis and Management By Laboratory Methods. 18th edn. Philadelphia: W.B. Saunders 1991. pp. 1264-1267.
11. Lo, S.C., Shih, J.W., Newton, P.B., et al. Virus-like infectious agent (VLIA) is a novel pathogenic Mycoplasma: Mycoplasma Incognitus. American Journal of Tropical Medicine and Hygiene 1989; 41: 586-600.
12. Hopps, H.E., Meyer, B.C., Barile, M.F., et al. Problems concerning "non-cultivable" mycoplasma contaminants in tissue cultures. Annals of the New York Academy of Science 1973; 225: 265-276.
13. Rawadi, G., and Dussurget, O. Advances in PCR-based detection of mycoplasmas contaminating cell cultures. PCR Methods and Applications 1995; 4: 199-208.
14. Razin, S. DNA probes and PCR in diagnosis of mycoplasma infections. Molecular and Cellular Probes 1994; 8: 497-511.
15. van Kuppeveld, F.J.M., van der Logt, J.T.M., Angulo, A.F., et al. Genus- and species-specific identification of Mycoplasmas by 16S rRNA amplification. Applied and Environmental Microbiology 1992; 58: 2606-2615.
16. Hopert, A., Uphoff, C.C., Wirth, M., Hauser, H., et al. Specificity and sensitivity of polymerase chain reaction (PCR) in comparison with other methods for the detection of mycoplasmas contamination in cell lines. Journal of Immunological Methods 1993; 164: 91-100.
17. Wang, H., Fadl, A.A., and Khan, M.I. Multiplex PCR for avian pathogenic mycoplasmas. Molecular and Cellular Probes 1997; 11: 211-216.
18. Kulski, J.K., Khinsoe, C., Pryce, T., and Christiansen, K. Use of a multiplex PCR to detect and identify Mycobacterium avium and M. intracellulare in blood culture fluids of AIDS patients. Journal of Clinical Microbiology 1995 33: 668-674.
19. van Kuppeveld, F.J.M., Johansson, K.E., Galama, J.M.D., et al. Detection of mycoplasma contamination in cell cultures by a Mycoplasma group-specific PCR. Applied and Environmental Microbiology 1994; 60: 149-152.
20. Hawkins, R.E., Rickman, L.S., Vermund, S.H., et al. Association of Mycoplasma and human immunodeficiency virus infection: Detection of amplified Mycoplasma fermentans DNA in blood. Journal of Infectious Diseases 1992; 165: 581-585.
21. Chingbingyong, M.I., and Hughes, C.V. Detection of Mycoplasma fermentans in human saliva with a polymerase chain reaction-based assay. Archives of Oral Biology 1996; 41: 311-314.
22. Berg, S., Luneberg, E., and Frosch, M. Development of an amplification and hybridization assay for the specific and sensitive detection of Mycoplasma fermentans. DNA Molecular and Cellular Probes 1996; 10: 7-14.
23. Lo, S.C., Buchholz, C.L., Wear, D.J., et al. Histopathology and doxycycline treatment in a previously healthy non-AIDS patient systematically infected by Mycoplasma fermentans (incognitus strain). Modern Pathology 1991; 4: 750-754.
24. Beecham, H.J., Lo, S.C., Lewis, D.E., et al. Recovery from fulminant infection with Mycoplasma fermentans (incognitus strain) in non-immunocompromised host. Lancet 1991; 338: 1014-1015.
25. Kovacic, R., Launay, V., Tuppin, P., et al. Search for the presence of six mycoplasma species in peripheral blood mononuclear cells of subjects seropositive and seronegative for human immunodeficiency virus. Journal of Clinical Microbiology 1996; 34: 1808-1810.