Calcium ions do accelerate the DNA binding of new antitumor-active platinum aminophosphonate complexes

European Journal of Inorganic Chemistry

Volumn , Issue 10, 1999, Pages 1655-1657

  Bloemink, Marieke J ^a   Diederen, Jeroen J H ^a   Dorenbos, Jaco P ^a   Heetebrij, Robert J ^a   Keppler, Bernhard K ^b   Reedijk, Jan ^a  

^a LEIDEN UNIVERSITY   (Netherlands)

^b UNIVERSITY OF VIENNA   (Austria)

Author keywords

Aminophosphonate; Antitumor agents; Calcium; Platinum Complexes

Indexed keywords

CALCIUM COMPOUNDS; PLATINUM COMPOUNDS; REACTION KINETICS;

AMINOPHOSPHONATES; ANTI-TUMORS; ANTITUMOUR AGENTS; CA 2+; CALCIUM IONS; DNA-BINDING; PHOSPHATE GROUP; PHOSPHONATE COMPLEX; PHOSPHONATE LIGANDS; PLATINUM COMPLEXES;

LIGANDS;

ANTINEOPLASTIC AGENT; CALCIUM ION; GUANOSINE DERIVATIVE; METAL CHELATE; PHOSPHATE; PHOSPHONIC ACID DERIVATIVE; PHOSPHORAMIDIC ACID DERIVATIVE; PLATINUM COMPLEX;

ARTICLE; CATALYSIS; CHELATION; CHEMICAL REACTION KINETICS; DRUG DNA BINDING; DRUG MECHANISM; DRUG STRUCTURE; MOLECULAR DYNAMICS; REACTION ANALYSIS;

EID: 0032850652     PISSN: 14341948     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-0682(199910)1999:10<1655::AID-EJIC1655>3.0.CO;2-5     Document Type: Article

References (21)

1. For some reviews see: W. I. Sundquist, S. J. Lippards, Coord. Chem. Rev. 1990, 100, 293. J. Reedijk, Inorg. Chim. Acta 1992, 198-200, 873. D. B. Zamble, S. J. Lippard, Trends Biochem. Sc. 1995, 20, 435. J. Reedijk, Chem. Comm. 1996, 801
2. For some reviews see: W. I. Sundquist, S. J. Lippards, Coord. Chem. Rev. 1990, 100, 293. J. Reedijk, Inorg. Chim. Acta 1992, 198-200, 873. D. B. Zamble, S. J. Lippard, Trends Biochem. Sc. 1995, 20, 435. J. Reedijk, Chem. Comm. 1996, 801
3. For some reviews see: W. I. Sundquist, S. J. Lippards, Coord. Chem. Rev. 1990, 100, 293. J. Reedijk, Inorg. Chim. Acta 1992, 198-200, 873. D. B. Zamble, S. J. Lippard, Trends Biochem. Sc. 1995, 20, 435. J. Reedijk, Chem. Comm. 1996, 801
4. For some reviews see: W. I. Sundquist, S. J. Lippards, Coord. Chem. Rev. 1990, 100, 293. J. Reedijk, Inorg. Chim. Acta 1992, 198-200, 873. D. B. Zamble, S. J. Lippard, Trends Biochem. Sc. 1995, 20, 435. J. Reedijk, Chem. Comm. 1996, 801
5. A. M. J. Fichtinger-Schepman, J. L. van der Veer, J. H. J. den Hartog, P. H. M. Lohman, J. Reedijk, Biochemistry 1985, 24, 707. A. M. J. Fichtinger-Schepman, A. T. van Oosterom, P. H. M. Lohman, F. Berends, Cancer Res. 1987, 47, 3000.
6. A. M. J. Fichtinger-Schepman, J. L. van der Veer, J. H. J. den Hartog, P. H. M. Lohman, J. Reedijk, Biochemistry 1985, 24, 707. A. M. J. Fichtinger-Schepman, A. T. van Oosterom, P. H. M. Lohman, F. Berends, Cancer Res. 1987, 47, 3000.
7. [3a] T. Klenner, P. Valenzuele-Paz, B. K. Keppler, G. Angres, H. R. Scherf, F. Wingen, D. Schmähl, Cancer Treat. Rev. 1990, 17, 253.
8. [3b] T. Klenner, F. Wingen, B. K. Keppler, B. Krempien, D. Schmähl, J. Cancer Res. Clin. Oncol. 1990, 116, 341.
9. [3c] T. Klenner, B. K. Keppler, F. Amelung, D. Schmähl, J. Cancer Res. Clin. Oncol. 1989, 115, S54.
10. [3d] B. K. Keppler, M. R. Berger, T. Klenner, M. E. Heim, Adv. Drug Res. 1990, 19, 243.
11. [3e] S. Frühauf, W. J. Zeller, Cancer Research 1991, 51, 2943.
12. F. Wingen, D. Schmähl, Drug Research 1985, 35, 1565.
13. Abbreviations used: bmpaa = bis(methylphosphate)aminoacetate; dach = diaminocyclohexane; ntmp nitrilotrismethylene-phosphonic acid; apmd = 1-amino-1-phenyl-methane-1,1-diphosphonic acid.
14. T. J. Einhäuser, M. Galanski, B. K. Keppler, Journal of Analytical Atomic Spectrometry, 1996, 11, 747-750.
15. M. J. Bloemink, J. P. Dorenbos, R. J. Heetebrij, B. K. Keppler, J. Reedijk, H. Zahn, H. Inorg. Chem. 1994, 33, 1127.
16. [8a] S. S. G. E. van Boom, J. Reedijk, J. Chem. Soc. Chem. Commun. 1993, 1397.
17. [8b] K. J. Barnham, M. I. Djuran, P. del S. Murdoch, P. J. Sadler, J. Chem Soc. Chem. Commun. 1994, 721.
18. M. Green, M. Garner, D. M. Orton, Transition Met. Chem. Weinheim (Ger.) 1992, 17, 164-176.
19. J. L. Wike-Hooley, J. Haveman, H. S. Reinhold, Radiother. Oncol. 1984, 2, 343.
20. M. L. G. Gardner, in: Medical acid-base balance; the basic principles, Bailiere Tindall, London, 1978, pp. 7-22.
21. T. Klenner, P. Valenzuele-Paz, F. Amelung, H. Münch, H. Zahn, B. K. Keppler, H. Blum, in: Metal Complexes in Chemotherapy (Ed.: B. K. Keppler), VCH Verlagsgesellschaft, Weinheim, 1993, 85-127.