메뉴 건너뛰기




Volumn 145, Issue 10, 1999, Pages 2947-2955

Identification of structural and functional domains of the tetracycline efflux protein TetA(P) from Clostridium perfringens

Author keywords

Clostridium perfringens; Efflux; Resistance; Tetracycline; Transmembrane domains

Indexed keywords

ANTIBIOTIC AGENT; BACTERIAL PROTEIN; MEMBRANE PROTEIN; MUTANT PROTEIN; TETRACYCLINE;

EID: 0032850188     PISSN: 13500872     EISSN: None     Source Type: Journal    
DOI: 10.1099/00221287-145-10-2947     Document Type: Article
Times cited : (15)

References (43)
  • 1
    • 0023789332 scopus 로고
    • Hybridization analysis of the class P tetracycline resistance determinant from the Clostridium perfringens R-plasmid, pCW3
    • Abraham, L. J., Berryman, D. I. & Rood, J. I. (1988). Hybridization analysis of the class P tetracycline resistance determinant from the Clostridium perfringens R-plasmid, pCW3. Plasmid 19, 113-120.
    • (1988) Plasmid , vol.19 , pp. 113-120
    • Abraham, L.J.1    Berryman, D.I.2    Rood, J.I.3
  • 2
    • 0026657163 scopus 로고
    • Membrane topology of the pBR322 tetracycline resistance protein. TetA-PhoA gene fusions and implications for the mechanism of TetA membrane insertion
    • Allard, J. D. & Bertrand, K. P. (1992). Membrane topology of the pBR322 tetracycline resistance protein. TetA-PhoA gene fusions and implications for the mechanism of TetA membrane insertion. J Biol Chem 267, 17809-17819.
    • (1992) J Biol Chem , vol.267 , pp. 17809-17819
    • Allard, J.D.1    Bertrand, K.P.2
  • 3
    • 0027509460 scopus 로고
    • Analysis of the topology of a membrane protein by using a minimum number of alkaline phosphatase fusions
    • Boyd, D., Traxler, B. & Beckwith, J. (1993). Analysis of the topology of a membrane protein by using a minimum number of alkaline phosphatase fusions. J Bacteriol 175, 553-556.
    • (1993) J Bacteriol , vol.175 , pp. 553-556
    • Boyd, D.1    Traxler, B.2    Beckwith, J.3
  • 4
    • 0028568176 scopus 로고
    • TopPred II: An improved software for membrane protein structure predictions
    • Claros, M. G. & von Heijne, G. (1994). TopPred II: an improved software for membrane protein structure predictions. Comput Appl Biosci 10, 685-686.
    • (1994) Comput Appl Biosci , vol.10 , pp. 685-686
    • Claros, M.G.1    Von Heijne, G.2
  • 5
    • 0024307647 scopus 로고
    • Topology of the transposon Tn10-encoded tetracycline resistance protein within the inner membrane of Escherichia coli
    • Eckert, B. & Beck, C. F. (1989). Topology of the transposon Tn10-encoded tetracycline resistance protein within the inner membrane of Escherichia coli. J Biol Chem 264, 11663-11670.
    • (1989) J Biol Chem , vol.264 , pp. 11663-11670
    • Eckert, B.1    Beck, C.F.2
  • 6
    • 0031470826 scopus 로고    scopus 로고
    • Genomic sequence of a lyme disease spirochaete, Borrelia burgdorferi
    • Fraser, C. M., Casjens, S., Huang, W. M. & 35 other authors (1997). Genomic sequence of a lyme disease spirochaete, Borrelia burgdorferi. Nature 390, 580-586.
    • (1997) Nature , vol.390 , pp. 580-586
    • Fraser, C.M.1    Casjens, S.2    Huang, W.M.3
  • 11
    • 0024995549 scopus 로고
    • Proton-linked sugar transport systems in bacteria
    • Henderson, P. J. (1990). Proton-linked sugar transport systems in bacteria. J Bioenerg Biomembr 22, 525-569.
    • (1990) J Bioenerg Biomembr , vol.22 , pp. 525-569
    • Henderson, P.J.1
  • 12
    • 0028999357 scopus 로고
    • The conserved motif, GXXX(D/E)(R/K)XG[X](R/K)(R/K), in hydrophilic loop 2/3 of the lactose permease
    • Jessen-Marshall, A. E., Paul, N. J. & Brooker, R. J. (1995). The conserved motif, GXXX(D/E)(R/K)XG[X](R/K)(R/K), in hydrophilic loop 2/3 of the lactose permease. J Biol Chem 270, 16251-16257.
    • (1995) J Biol Chem , vol.270 , pp. 16251-16257
    • Jessen-Marshall, A.E.1    Paul, N.J.2    Brooker, R.J.3
  • 13
    • 0030780608 scopus 로고    scopus 로고
    • Glutamate residues located within putative transmembrane helices are essential for TetA(P)-mediated tetracycline efflux
    • Kennan, R. M., McMurry, L. M., Levy, S. B. & Rood, J. I. (1997). Glutamate residues located within putative transmembrane helices are essential for TetA(P)-mediated tetracycline efflux. J Bacteriol 179, 7011-7015.
    • (1997) J Bacteriol , vol.179 , pp. 7011-7015
    • Kennan, R.M.1    McMurry, L.M.2    Levy, S.B.3    Rood, J.I.4
  • 14
    • 0029999231 scopus 로고    scopus 로고
    • Asp-285 of the metal-tetracycline/H+ antiporter of Escherichia coli is essential for substrate binding
    • Kimura, T. & Yamaguchi, A. (1996). Asp-285 of the metal-tetracycline/H+ antiporter of Escherichia coli is essential for substrate binding. FEBS Lett 388, 50-52.
    • (1996) FEBS Lett , vol.388 , pp. 50-52
    • Kimura, T.1    Yamaguchi, A.2
  • 17
    • 0020475449 scopus 로고
    • A simple method for displaying the hydropathic character of a protein
    • Kyte, J. & Doolittle, R. F. (1982). A simple method for displaying the hydropathic character of a protein. J Mol Biol 157, 105-132.
    • (1982) J Mol Biol , vol.157 , pp. 105-132
    • Kyte, J.1    Doolittle, R.F.2
  • 18
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli, U. K. (1970). Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680-685.
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 19
    • 0026588343 scopus 로고
    • Active efflux mechanisms for antimicrobial resistance
    • Levy, S. B. (1992). Active efflux mechanisms for antimicrobial resistance. Antimicrob Agents Chemother 36, 695-703.
    • (1992) Antimicrob Agents Chemother , vol.36 , pp. 695-703
    • Levy, S.B.1
  • 20
    • 0023269955 scopus 로고
    • Energy-dependent efflux mediated by class L (tetL) tetracycline resistance determinant from streptococci
    • McMurry, L. M., Park, B. H., Burdett, V. & Levy, S. B. (1987). Energy-dependent efflux mediated by class L (tetL) tetracycline resistance determinant from streptococci. Antimicrob Agents Chemother 31, 1648-1650.
    • (1987) Antimicrob Agents Chemother , vol.31 , pp. 1648-1650
    • McMurry, L.M.1    Park, B.H.2    Burdett, V.3    Levy, S.B.4
  • 21
    • 0026677558 scopus 로고
    • Genetic analysis of the tetA(C) gene on plasmid pBR322
    • McNicholas, P., Chopra, I. & Rothstein, D. M. (1992). Genetic analysis of the tetA(C) gene on plasmid pBR322. J Bacteriol 174, 7926-7933.
    • (1992) J Bacteriol , vol.174 , pp. 7926-7933
    • McNicholas, P.1    Chopra, I.2    Rothstein, D.M.3
  • 22
  • 23
    • 0024202852 scopus 로고
    • Characterization of the tetracycline resistance gene of plasmid pT181 of Staphylococcus aureus
    • Mojumdar, M. & Khan, S. A. (1988). Characterization of the tetracycline resistance gene of plasmid pT181 of Staphylococcus aureus. J Bacteriol 170, 5522-5528.
    • (1988) J Bacteriol , vol.170 , pp. 5522-5528
    • Mojumdar, M.1    Khan, S.A.2
  • 25
    • 0029034869 scopus 로고
    • Molecular characterization of the staphylococcal multidrug resistance export protein QacC
    • Paulsen, I. T., Brown, M. H., Dunstan, S. J. & Skurray, R. A. (1995). Molecular characterization of the staphylococcal multidrug resistance export protein QacC. J Bacteriol 177, 2827-2833.
    • (1995) J Bacteriol , vol.177 , pp. 2827-2833
    • Paulsen, I.T.1    Brown, M.H.2    Dunstan, S.J.3    Skurray, R.A.4
  • 26
    • 0029845047 scopus 로고    scopus 로고
    • Proton-dependent multidrug efflux systems
    • Paulsen, I. T., Brown, M. H. & Skurray, R. A. (1996). Proton-dependent multidrug efflux systems. Microbiol Rev 60, 575-608.
    • (1996) Microbiol Rev , vol.60 , pp. 575-608
    • Paulsen, I.T.1    Brown, M.H.2    Skurray, R.A.3
  • 27
    • 0030273002 scopus 로고    scopus 로고
    • Tetracycline resistance determinants: Mechanisms of action, regulation of expression, genetic mobility, and distribution
    • Roberts, M. C. (1996). Tetracycline resistance determinants: mechanisms of action, regulation of expression, genetic mobility, and distribution. FEMS Microbiol Rev 19, 1-24.
    • (1996) FEMS Microbiol Rev , vol.19 , pp. 1-24
    • Roberts, M.C.1
  • 28
    • 0031025290 scopus 로고    scopus 로고
    • Topology of Legionella pneumophila DotA: An inner membrane protein required for replication in macrophages
    • Roy, C. R. & Isberg, R. R. (1997). Topology of Legionella pneumophila DotA: an inner membrane protein required for replication in macrophages. Infect Immun 65, 571-578.
    • (1997) Infect Immun , vol.65 , pp. 571-578
    • Roy, C.R.1    Isberg, R.R.2
  • 29
    • 0030163126 scopus 로고    scopus 로고
    • Tetracyclines: Antibiotic action, uptake, and resistance mechanisms
    • Schnappinger, D. & Hillen, W. (1996). Tetracyclines: antibiotic action, uptake, and resistance mechanisms. Arch Microbiol 165, 359-369.
    • (1996) Arch Microbiol , vol.165 , pp. 359-369
    • Schnappinger, D.1    Hillen, W.2
  • 30
    • 0027446547 scopus 로고
    • Membrane topology model of escherichia coli alpha-ketoglutarate permease by PhoA fusion analysis
    • Seol, W. & Shatkin, A. J. (1993). Membrane topology model of Escherichia coli alpha-ketoglutarate permease by PhoA fusion analysis. J Bacteriol 175, 565-567.
    • (1993) J Bacteriol , vol.175 , pp. 565-567
    • Seol, W.1    Shatkin, A.J.2
  • 31
    • 0028217752 scopus 로고
    • The Clostridium perfringens Tet P determinant comprises two overlapping genes: TetA(P), which mediates active tetracycline efflux, and tetB(f), which is related to the ribosomal protection family of tetracycline-resistance determinants
    • Sloan, J., McMurry, L. M., Lyras, D., Levy, S. B. & Rood, J. I. (1994). The Clostridium perfringens Tet P determinant comprises two overlapping genes: tetA(P), which mediates active tetracycline efflux, and tetB(f), which is related to the ribosomal protection family of tetracycline-resistance determinants. Mol Microbiol 11, 403-415.
    • (1994) Mol Microbiol , vol.11 , pp. 403-415
    • Sloan, J.1    McMurry, L.M.2    Lyras, D.3    Levy, S.B.4    Rood, J.I.5
  • 32
    • 0026768854 scopus 로고
    • Bacterial resistance to tetracycline: Mechanisms, transfer, and clinical significance
    • Speer, B. S., Shoemaker, N. B. & Salyers, A. A. (1992). Bacterial resistance to tetracycline: mechanisms, transfer, and clinical significance. Clin Microbiol Rev 5, 387-399.
    • (1992) Clin Microbiol Rev , vol.5 , pp. 387-399
    • Speer, B.S.1    Shoemaker, N.B.2    Salyers, A.A.3
  • 33
    • 0030835739 scopus 로고    scopus 로고
    • The complete genome sequence of the gastric pathogen Helicobacter pylori
    • Tomb, J. F., White, O., Kerlavage, A. R. & 39 other authors (1997). The complete genome sequence of the gastric pathogen Helicobacter pylori. Nature 388, 539-547.
    • (1997) Nature , vol.388 , pp. 539-547
    • Tomb, J.F.1    White, O.2    Kerlavage, A.R.3
  • 34
    • 0025045111 scopus 로고
    • + antiporter of Escherichia coli encoded by a transposon, Tn10. The role of the conserved dipeptide, Ser65-Asp66, in tetracycline transport
    • + antiporter of Escherichia coli encoded by a transposon, Tn10. The role of the conserved dipeptide, Ser65-Asp66, in tetracycline transport. J Biol Chem 265, 15525-15530.
    • (1990) J Biol Chem , vol.265 , pp. 15525-15530
    • Yamaguchi, A.1    Ono, N.2    Akasaka, T.3    Noumi, T.4    Sawai, T.5
  • 35
    • 0025253460 scopus 로고
    • Transport of divalent cations with tetracycline as mediated by the transposon Tn10-encoded tetracycline resistance protein
    • Yamaguchi, A., Udagawa, T. & Sawai, T. (1990b). Transport of divalent cations with tetracycline as mediated by the transposon Tn10-encoded tetracycline resistance protein. J Biol Chem 265, 4809-4813.
    • (1990) J Biol Chem , vol.265 , pp. 4809-4813
    • Yamaguchi, A.1    Udagawa, T.2    Sawai, T.3
  • 36
    • 0026726164 scopus 로고
    • + antiporter of Escherichia coli encoded by transposon Tn10. Roles of the aspartyl residues located in the putative transmembrane helices
    • + antiporter of Escherichia coli encoded by transposon Tn10. Roles of the aspartyl residues located in the putative transmembrane helices. J Biol Chem 267, 7490-7498.
    • (1992) J Biol Chem , vol.267 , pp. 7490-7498
    • Yamaguchi, A.1    Akasaka, T.2    Ono, N.3    Someya, Y.4    Nakatani, M.5    Sawai, T.6
  • 38
    • 0026657365 scopus 로고
    • + antiporter encoded by transposon Tn10 of Escherichia coli
    • + antiporter encoded by transposon Tn10 of Escherichia coli. Biochemistry 31, 8344-8348.
    • (1992) Biochemistry , vol.31 , pp. 8344-8348
    • Yamaguchi, A.1    Nakatani, M.2    Sawai, T.3
  • 39
    • 0026670486 scopus 로고
    • + antiporter of Escherichia coli encoded by transposon Tn10. The role of a conserved sequence motif, GXXXXRXGRR, in a putative cytoplasmic loop between helices 2 and 3
    • + antiporter of Escherichia coli encoded by transposon Tn10. The role of a conserved sequence motif, GXXXXRXGRR, in a putative cytoplasmic loop between helices 2 and 3. J Biol Chem 267, 19155-19162.
    • (1992) J Biol Chem , vol.267 , pp. 19155-19162
    • Yamaguchi, A.1    Someya, Y.2    Sawai, T.3
  • 41
    • 0027241494 scopus 로고
    • The in vivo assembly and function of the N-and C-terminal halves of the Tn10-encoded TetA protein in Escherichia coli
    • Yamaguchi, A., Someya, Y. & Sawai, T. (1993b). The in vivo assembly and function of the N-and C-terminal halves of the Tn10-encoded TetA protein in Escherichia coli. FEBS Lett 324, 131-135.
    • (1993) FEBS Lett , vol.324 , pp. 131-135
    • Yamaguchi, A.1    Someya, Y.2    Sawai, T.3
  • 43
    • 0029189180 scopus 로고
    • Cloning and sequencing of a 36-kb region of the Bacillus subtilis genome between the gnt and iol operons
    • Yoshida, K., Seki, S., Fujimura, M., Miwa, Y. & Fujita, Y. (1995). Cloning and sequencing of a 36-kb region of the Bacillus subtilis genome between the gnt and iol operons. DNA Res 2, 61-69.
    • (1995) DNA Res , vol.2 , pp. 61-69
    • Yoshida, K.1    Seki, S.2    Fujimura, M.3    Miwa, Y.4    Fujita, Y.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.