Neutrophil activation and mediators of inflammation in chronic venous insufficiency

Journal of Vascular Research

Volumn 36, Issue SUPPL. 1, 1999, Pages 24-36

  Coleridge Smith, Philip D ^a,b  

^a ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

^b MIDDLESEX HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CD11B ANTIGEN; DAFLON; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; INTERCELLULAR ADHESION MOLECULE 1; PADGEM PROTEIN; PENTOXIFYLLINE; PROSTAGLANDIN E1; VASCULAR CELL ADHESION MOLECULE 1;

ANTIINFLAMMATORY ACTIVITY; CLINICAL TRIAL; CONFERENCE PAPER; DRUG EFFICACY; ENDOTHELIUM INJURY; HUMAN; INFLAMMATION; INTRAVENOUS DRUG ADMINISTRATION; LEUKOCYTE ACTIVATION; MONOCYTE; NEUTROPHIL; PRIORITY JOURNAL; ULCER; VEIN INSUFFICIENCY; VENOUS PRESSURE;

EID: 0032849078     PISSN: 10181172     EISSN: None     Source Type: Journal    
DOI: 10.1159/000054071     Document Type: Conference Paper

References (48)

1. Cornu-Thenard C, Boivin P, Baud J-M, de Vincenzi I, Carpentier PH: Importance of the familial factor in varicose disease. J Dermatol Surg Oncol 1994;20:313-326.
2. Grossman D, Heald DW, Wang C, Rinder HM: Activated protein C resistance and anti-cardiolipin antibodies in patients with venous leg ulcers. J Am Acad Dermatol 1997;37:409-413.
3. Nicolaides AN, Zukowski A, Lewis R, Kyprianou P, Malouf GM: Venous pressure measurements in venous problems; in Bergan JJ, Yao JST (eds): Surgery of the Veins, Orlando, Grune & Stratton, 1985, pp 111-118.
4. Dodd H, Cockett FB: The pathology and surgery of the veins of the lower limb. Edinburgh, Churchill Livingstone, 1976.
5. Hoare MC, Nicolaides AN, Miles CR, Shull K, Jury RP, Needham T, Dudley HAF: The role of primary varicose veins in venous ulceration. Surgery 1982;92:450-453.
6. Kistner RL: Primary venous valve incompetence of the leg. Am J Surg 1980;140:218-224.
7. Pollack AA, Taylor BE, Myers TT, Wood EH: The effect of exercise and body position on the venous pressure at the ankle in patients having venous valvular defects. J Clin Invest 1949;28: 559-563.
8. Braide M, Amundson B, Chien S, Bagge U: Quantitative studies of leukocytes on the vascular resistance in a skeletal muscle preparation. Microvasc Res 1984;27:331-352.
9. Engler RL, Dahlgren MD, Peterson MA, Dobbs A, Schmid-Schoenbein GW: Accumulation of polymorphonuclear leukocytes during three hour myocardial ischemia. Am J Physiol 1986;251:H93-H100.
10. Romson JL, Hook BG, Kunkel SL, Abrams GD, Schork MA, Lucchcsi BR: Reduction of the extent of ischemic myocardial injury by neutrophil depletion in the dog. Circulation 1983;67:1016-1023.
11. Wilson JW: Leukocyte sequestration and morphologic augmentation in the pulmonary network following haemorrhagic shock and related forms of stress. Adv Microcirc 1972;4:197-232.
12. Linas SL, Shanley PF, Whittenburg D, Berger E, Repine JE: Neutrophils accentuate ischemia-reperfusion injury in isolated perfused rat kidneys. Am J Physiol 1988;255:F728-F735.
13. Yamakawa T, Suguyama I, Niimi H: Behaviour of white blood cells in microcirculation of the cat brain cortex during hemorrhagic shock. Intravital microscopic study. Int J Microcirc Clin Exp 1984;3:554.
14. Braide M, Blixt A, Bagge U: Leukocyte effects on the vascular resistance and glomerular filtration of the isolated rat kidney at normal and low now rates. Circ Shock 1986;20:71-80.
15. Weissman G, Smolen JE, Korchak HM: Release of inflammatory mediators from stimulated neutrophils. N Engl J Med 1980;303:27-34.
16. Babior BM: Oxidants from phagocytes: Agents of defense and destruction. Blood 1984;64: 959-966.
17. Moyses C, Cederholm-Willams SA, Michel CC: Haemoconcentration and the accumulation of white cells in the feet during venous stasis. Int J Microcirc Clin Exp 1987;5:311-320.
18. Thomas PRS, Nash GB, Dormandy JA: White cell accumulation in the dependent legs of patients with venous hypertension: A possible mechanism for trophic changes in the skin. Br Med J 1988;296:1693-1695.
19. Coleridge Smith PD: Treatment of microcirculation disorders in venous leg ulcer; in Messmer K (ed): Microcirculation in Chronic Venous Insufficiency. Prog Appl Microcirc. Basel, Karger, 1999, vol 23, pp 121-141.
20. Scott HJ, McMullin GM, Coleridge Smith PD, Scurr JH: Venous ulceration and the role of the white blood cell. J Med Sci Tech 1990;14:184-187.
21. Bollinger A, Haselbach P, Schnewlin G, Jünger M: Microangiopathy due to chronic venous incompetence evaluated by fluorescence videomicroscopy; in Negus D, Jantet G (eds): Phlebology '85. London, Libbey, 1986.
22. Browse NL, Burnand KG: The cause of venous ulceration. Lancet 1982;ii:243-245.
23. Franzeck UK, Speiser D, Haselbach P, Bollinger A: Morphologic and dynamic microvascular abnormalities in chronic venous incompetence (CVI); in Davy A, Stemmer R (eds): Phlebologie '89. Montrouge, Libbey Eurotext, 1989, pp 104-107.
24. Coleridge Smith PD, Thomas P, Scurre JH, Dormandy JA: Causes of venous ulceration: A new hypothesis. Br Med J 1988;296:1726-1727.
25. Burnand KG, Whimster I, Naidoo A, Browse NL: Pericapillary fibrin in the ulcer-bearing skin of the leg: The cause of lipodermatosclerosis and venous ulceration. Br Med J 1982;285: 1071-1072.
26. Haselbach P, Vollenweider U, Moneta G, Bollinger A: Microangiopathy in severe chronic venous insufficiency evaluated by fluorescence video-microscopy. Phlebology 1986;1:159-169.
27. Wilkinson LS, Bunker C, Edwards JC, Scurr JH, Coleridge Smith PD: Leukocytes: Their role in the etiopathogenesis of skin damage in venous disease. J Vasc Surg 1993;17:669-675.
28. Veraart JC, Verhaegh ME, Neumann HA, Hulsmans RF, Arends JW: Adhesion molecule expression in venous leg ulcers. Vasa 1993;22: 213-218.
29. Weyl A, Vanscheidt W, Weiss JM, Peschen M, Schöpf E, Simon J: Expression of the adhesion molecules ICAM-1, VCAM-1, and E-selectin and their ligands VLA-4 and LFA-1 in chronic leg ulcers. J Am Acad Dermatol 1996;34:418-423.
30. Herrick SE, Sloan P, McGurk M, Freak L, McCollum CN, Ferguson MW: Sequential changes in histologic pattern and extracellular matrix deposition during the healing of chronic venous ulcers. Am J Pathol 1992;141:1085-1095.
31. Scott HJ, McMullin GM, Coleridge Smith PD, Scurr JH: A histological study into white blood cells and their association with lipodermalosclerosis and ulceration. Br J Surg 1990;78: 210-211.
32. Falanga V, Kruskal J, Franks JJ: Fibrin- and fibrinogen-related antigens in patients with venous disease and venous ulceration. Arch Dermatol 1991;127:75-78.
33. Burnand KG, Whimster I, Clemenson G, Thomas ML, Browse NL: The relationship between the number of capillaries in the skin of the venous ulcer-bearing area of the lower leg and the fall in foot vein pressure during exercise. Br J Surg 1981;68:297-300.
34. Pardoe HD: The expression of angiogenic growth factors in the skin of patients with chronic venous disease of the lower limb; MSc thesis. London, 1996, pp 1-61.
35. Shields DA, Andaz S, Abeysinghe RD, Porter JB, Scurr JH, Coleridge Smith PD: Neutrophil activation in experimental ambulatory venous hypertension. Phlebology 1994;9:119-124.
36. Shields D, Andaz SK, Timothy-Antoine CA, Scurr JH, Porter JB: CD11b/CD18 as a marker of neutrophil adhesion in experimental ambulatory venous hypertension. Phlebology 1995; 10(suppl 1):108-109.
37. Saharay M, Shields DA, Porter JB, Scurr JH, Coleridge-Smith PD: Leukocyte activity in the microcirculation of the leg in patients with chronic venous disease. J Vasc Surg 1997;26: 265-273.
38. Saharay M, Shields DA, Porter JB, Scurr JH, Coleridge Smith PD: Leukocyte activity in the microcirculation of the leg in patients with chronic venous disease. J Vasc Surg 1997;26: 265-273.
39. Shields DA, Andaz S, Abeysinghe RD, Porter JB, Scurr JH, Coleridge Smith PD: Plasma lactoferrin as a marker of white cell degranulation in venous disease. Phlebology 1994;9:55-58.
40. Shields DA, Andaz SK, Sarin S, Scurr JH, Coleridge Smith PD: Plasma elastase in venous disease. Br J Surg 1994;81:1496-1499.
41. Shields D, Saharay M, Timothy-Antoine CA, Porter JB, Scurr JH: Neutrophil CD11b expression in patients with venous disease. Phlebology 1995;10(suppl 1):108-109.
42. Franzeck UK, Speiser D, Haselbach P, Bollinger A: Morphologic and dynamic microvascular abnormalities in chronic venous incompetence (CVI); in Davy A, Stemmer R, Phlebologie 1989. Montrogue, Libbey Eurotext 1989, pp 104-107.
43. Layer GT, Stacey MC, Burnand KG: Stanozolol and the treatment of venous ulceration - an interim report. Phlebology 1986;1:197-203.
44. Sullivan GW, Carper HT, Novick WJ, Mandell GL: Inhibition of the inflammatory action of interleukin-1 and tumour necrosis factor (alpha) on neutrophil function of pentoxifylline. Infect Immun 1988;56:1722-1729.
45. Colgan M-P, Dormandy JA, Jones PW, Schraibman IG, Shanik DG: Oxpentifylline treatment of venous ulcers of the leg. Br Med J 1990;300:972-975.
46. Dale JJ, Ruckley CV, Harper DR, Gibson B, Nelson EA, Prescott RJ: A randomised double-blind placebo controlled trial of oxpentifylline in the treatment of venous leg ulcers. Phlebology 1995;10(suppl 1):917-918.
47. Anonymous: Oxpentifylline for venous leg ulcers. Drug Ther Bull 1991;29:59-60.
48. 1 in the treatment of venous ulcers - a double-blind, placebo-controlled trial. Vasa 1989 (suppl 28):39-43.