Inhibition of baroreflex vagal bradycardia by selective stimulation of arterial chemoreceptors in rats

Experimental Physiology

Volumn 84, Issue 5, 1999, Pages 897-906

  Murata, Tomohiro ^a   Otsu, Kazuya ^a   Kobayashi, Masayoshi ^a   Nosaka, Shoichiro ^a  

^a MIE UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

PENTOBARBITAL; SODIUM CYANIDE; SUXAMETHONIUM; URETHAN;

ANESTHESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; AORTA; ARTERY; ARTICLE; ARTIFICIAL VENTILATION; BLOOD PRESSURE; BRADYCARDIA; CAROTID SINUS NERVE; CHEMORECEPTOR; CONTROLLED STUDY; DENERVATION; DOSE RESPONSE; ELECTROSTIMULATION; HEART RATE; HYPOXIA; MALE; NERVE STIMULATION; NERVE TRANSECTION; NONHUMAN; PRESSORECEPTOR REFLEX; RAT; SPINAL CORD TRANSSECTION; STIMULATION; VAGUS NERVE;

EID: 0032848555     PISSN: 09580670     EISSN: None     Source Type: Journal    
DOI: 10.1017/S0958067099018898     Document Type: Article

References (32)

1. BLESSING, W. W., YU, Y. & NALIVAIKO, E. (1999). Medullary projections of rabbit carotid sinus nerve. Brain Research 816, 405-410.
2. BROPHY, S., FORD, T. W., CAREY, M. & JONES, J. F. X. (1999). Activity of aortic chemoreceptors in the anaesthetized rat. Journal of Physiology 514, 821-828.
3. CHENG, Z., POWLEY, T. L., SCHWABER, J. S. & DOYLE, F. J. III (1997). A laser confocal microscopic study of vagal afferent innervation of rat aortic arch: chemoreceptors as well as baroreceptors. Journal of the Autonomic Nervous System 67, 1-14.
4. DONOGHUE, S., FELDER, R. B., JORDAN, D. & SPYER, K. M. (1984). The central projections of carotid baroreceptors and chemoreceptors in the cat: A neurophysiological study. Journal of Physiology 347, 397-409.
5. ECKBERG, D. L., BASTOW, H. III & SCRUBY, A. E. (1982). Modulation of human sinus node function by systemic hypoxia. Journal of Applied Physiology 52, 570-577.
6. ERDEMLI, G., XU, Y. Z. & KRNJEVIC, K. (1998). Potassium conductance causing hyperpolarization of CA1 hippocampal neurons during hypoxia. Journal of Neurophysiology 80, 2378-2390.
7. GOLANOV, E. V. & REIS, D. J. (1996). Contribution of oxygen-sensitive neurons of the rostral ventrolateral medulla to hypoxic cerebral vasodilatation in the rat. Journal of Physiology 495, 201-216.
8. GROOM, A. S. & MALPAS, S. C. (1997). Baroreflex control of heart rate during hypoxia and hypercapnia in chronically hypertensive rabbits. Clinical and Experimental Pharmacology and Physiology 24, 229-234.
9. GUATTEO, E., MERCURI, N. B., BERNARDI, G. & KNÖPFEL, T. (1998). Intracellular sodium and calcium homeostasis during hypoxia in dopamine neurons of rat substantia nigra pars compacta. Journal of Neurophysiology 80, 2237-2243.
10. HILTON, S. M. & MARSHALL, J. M. (1982). The pattern of cardiovascular response to carotid chemoreceptor stimulation in the cat. Journal of Physiology 326, 495-513.
11. KALIA, M. & WELLES, R. V. (1980). Brain stem projections of the aortic nerve in the cat: a study using tetramethyl benzidine as the substrate for horseradish peroxidase. Brain Research 188, 23-32.
12. KNUDTZON, J., OWE, J. O. & AARS, H. (1991). Barorellex responsiveness during hypobaric hypoxia. Aviation Space and Environmental Medicine 62, 397-402.
13. KOBAYASHI, M., CHENG, Z. B., TANAKA, K. & NOSAKA, S. (1999). Is the aortic depressor nerve involved in arterial chemoreflexes in rats. Journal of the Autonomic Nervous System (in the Press).
14. KONGO, M., YAMAMOTO, R., KOBAYASHI, M. & NOSAKA, S. (1999). Hypoxia inhibits baroreflex vagal bradycardia via a central action in anaesthetized rats. Experimental Physiology 84, 47-56.
15. KORNER, P. I. (1979). Central nervous control of autonomie cardiovascular function. In Handbook of Physiology, section 2, Heart, vol. 1, ed. BERNE, R. M., SPERELAKIS, N. & GEIGER, S. R., pp. 691-739. American Physiological Society, Bethesda.
16. 1 adrenergic neurons. Neuroscience 69, 601-618.
17. LUHMANN, H. J. & HEINEMANN, U. (1992). Hypoxia-induced functional alterations in adult rat neocortex. Journal of Neurophysiology 67, 798-811.
18. MARSHALL, J. M. (1981). Interaction between the responses to stimulation of peripheral chemoreceptors and baroreceptors: the importance of chemoreceptor activation of the defence areas. Journal of the Autonomic Nervous System 3, 169-186.
19. MARSHALL, J. M. (1994). Peripheral chemoreceptors and cardiovascular regulation. Physiological Reviews 74, 543-594.
20. MCQUEEN, D. S. (1980). Effects of acetylcholine and sodium cyanide on cat carotid baroreceptors. British Journal of Pharmacology 69, 433-440.
21. NOSAKA, S. (1996). Review. Modifications of arterial baroreflexes: obligatory roles in cardiovascular regulation in stress and poststress recovery. Japanese Journal of Physiology 46, 271-288.
22. NOSAKA, S., INUI, K., MURASE, S. & MURATA, K. (1996). A prejunctional mechanism in midbrain periaqueductal gray inhibition of vagal bradycardia in rats. American Journal of Physiology 270, R373-382.
23. NOSAKA, S., MURATA, K., INUI, K. & MURASE, S. (1993). Arterial baroreflex inhibition by midbrain periaqueductal grey in anaesthetized rats. Pflügers Archiv 424, 266-275.
24. NOSAKA, S., NAKASE, N. & MURATA, K. (1989). Somatosensory and hypothalamic inhibitions of baroreflex vagal bradycardia in rats. Pflügers Archiv 413, 656-666.
25. PISARRI, T. E. & KENDRICK, J. E. (1984). Reduced effectiveness of the carotid baroreflex during arterial hypoxia in dogs. American Journal of Physiology 247, H623-630.
26. SAPRU, H. N., GONZALEZ, E. & KRIEGER, A. J. (1981). Aortic depressor nerve stimulation in the rat: Cardiovascular and respiratory responses. Brain Research Bulletin 6, 393-398.
27. SAPRU, H. N. & KRIEGER, A. J. (1977). Carotid and aortic chemoreceptor functions in the rat. Journal of Applied Physiology 42, 344-348.
28. SUN, M. K. & REIS, D. J. (1994a). Hypoxia selectively excites vasomotor neurons of rostral ventrolateral medulla in rats. American Journal of Physiology 266, R245-256.
29. 2+ currents in pacemaker neurones of rat rostral ventrolateral medulla in vitro. Journal of Physiology 476, 101-116.
30. SUN, M. K. & REIS, D. J. (1995). NMDA receptor-mediated sympathetic chemoreflex excitation of RVL-spinal vasomotor neurones in rats. Journal of Physiology 482, 53-68.
31. TANAKA, K., INUI, K., KOBAYASHI, M., MURASE, S. & NOSAKA, S. (1998). Hereditarily elongated carotid sinus nerve in a rat colony. Journal of the Autonomic Nervous System 69, 190-197.
32. ATP channel mediation of anoxia-induced outward current in rat dorsal vagal neurons in vitro. Journal of Physiology 487, 37-50.