Conserved extracellular cysteine residues in the inwardly rectifying potassium channel Kir2.3 are required for function but not expression in the membrane

FEBS Letters

Volumn 458, Issue 3, 1999, Pages 393-399

  Bannister, J P A ^a   Young, B A ^a   Sivaprasadarao, A ^a   Wray, D ^a  

^a UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

Cysteine; Disulfide bond; Expression; Inward rectifier; Potassium channel

Indexed keywords

POTASSIUM CHANNEL;

ANIMAL CELL; ARTICLE; DISULFIDE BOND; MEMBRANE TRANSPORT; MUTATION; NONHUMAN; OOCYTE; POTASSIUM CURRENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; RETICULOCYTE LYSATE; RNA TRANSLATION; SITE DIRECTED MUTAGENESIS;

ANIMALS; CONSERVED SEQUENCE; CYSTEINE; FLUORESCENT ANTIBODY TECHNIQUE; MEMBRANE PROTEINS; MICE; MICROINJECTIONS; MUTATION; OOCYTES; PATCH-CLAMP TECHNIQUES; PEPTIDES; POTASSIUM CHANNELS; POTASSIUM CHANNELS, INWARDLY RECTIFYING; PROTEIN BIOSYNTHESIS; RETICULOCYTES; RNA, MESSENGER; XENOPUS;

EID: 0032847086     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(99)01096-0     Document Type: Article

References (21)

1. Vaca L., Licea A., Possani L.D. Am. J. Physiol. 270:1996;C819-C824.
2. Lesage F., Duprat F., Fink M., Guillemare E., Coppola T., Lazdunski M., Hugnot J.P. FEBS Lett. 353:1994;37-42.
3. Kamb A., Iverson L.E., Tanouye M.A. Cell. 50:1987;405-413.
4. Baumann A., Jentgens I.K., Muller R., Holtkamp M.F., Seidel R., Kecskemethy N., Casal J., Ferrus A., Pongs O. EMBO J. 11:1987;3419-3429.
5. Tinker A., Jan Y.N., Jan L.Y. Cell. 87:1996;857-868.
6. Xu J., Yu W., Jan Y.N., Jan L.Y., Li M. J. Biol. Chem. 279:1995;24761-24768.
7. Lee T.E., Philipson L.H., Kuznestsov A., Nelson D.J. Biophys. J. 66:1994;667-673.
8. Mackinnon R. Nature. 350:1991;232-235.
9. Yang J., Jan N.Y., Jan L.Y. Neuron. 15:1995;1441-1447.
10. Nagaya N., Papazian D.M. J. Biol. Chem. 272:1997;3022-3027.
11. Zerangue N., Schwappach B., Jan Y.N., Jan L.Y. Neuron. 22:1999;537-548.
12. Lesage F., Reyes R., Fink M., Duprat F., Guillemare E., Lazdunski M. EMBO J. 15:1996;6400-6407.
13. Schulteis C.T., Nagaya N., Papazian D.M. Biochemistry. 35:1996;12133-12140.
14. Bannister J.P.A., Young B.A., Sivaprasadarao A., Wray D. Br. J. Pharmacol. 123:1998;37P.
15. Kunkel T.A., Roberts J.D., Zakour R.A. Methods Enzymol. 154:1987;367-382.
16. Sambrook, J., Fritsch, E.F. and Maniatis, T. (1989) Molecular Cloning, pp. 7.43-7.45, Cold Spring Harbour Laboratory Press, Cold Spring Harbour, NY.
17. Wilson G.G., O'Neil C.A., Sivaprasadarao A., Findlay J.B.C., Wray D. Pflugers Arch. 428:1994;186-193.
18. Guibert C., Beech D.J. J. Physiol. 514:1999;843-856.
19. Morishige K.I., Takahashi N., Jahangir A., Yamada M., Koyama H., Zanelli J.S., Kurachi Y. FEBS Lett. 346:1994;251-256.
20. Cho, H.C., Jan, L.Y. and Backx, P. (1999) Biophysical J. 76, Mpos217.
21. Leyland, M.L., Dart, C., Spencer, P.J., Sutcliffe, M.J. and Stanfield, P.R. (1999) Abstracts, The Physiological Society, London, April 1999, PC60.