Hyperthyroidism is associated with preserved preconditioning capacity but intensified and accelerated ischaemic contracture in rat heart

Basic Research in Cardiology

Volumn 94, Issue 4, 1999, Pages 254-260

  Pantos, C I ^a   Cokkinos, D D ^a   Tzeis, S M ^a   Malliopoulou, V ^a   Mourouzis, I S ^a   Carageorgiou, H C ^a   Limas, C ^b   Varonos, D V ^a   Cokkinos, D V ^b  

^a UNIVERSITY OF ATHENS   (Greece)

^b ONASSIS CARDIAC SURGERY CENTER   (Greece)

Author keywords

Hyperthyroidism; Ischaemic contracture; Ischaemic preconditioning; Isolated rat heart

Indexed keywords

THYROXINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; HEART MUSCLE CONTRACTURE; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; HYPERTHYROIDISM; ISOLATED HEART; MALE; NONHUMAN; RAT;

ADENOSINE TRIPHOSPHATE; ANIMALS; BODY WEIGHT; HYPERTHYROIDISM; ISCHEMIC PRECONDITIONING; MALE; MYOCARDIAL CONTRACTION; RATS; RATS, WISTAR; VENTRICULAR FUNCTION, LEFT;

EID: 0032846863     PISSN: 03008428     EISSN: None     Source Type: Journal    
DOI: 10.1007/s003950050150     Document Type: Article

References (24)

1. Buser PT, Wikman Coffelt J, Wu ST, Derugin N, Parmley WW, Higgins CB (1990) Postischaemic recovery of mechanical performance and energy metabolism in the presence of left ventricular hypertrophy. A 3IP-MRS study. Circ Res 66: 735-746
2. Chen-Zion M, Bassukevitz Y, Beitner R (1995) Rapid changes in carbohydrate metabolism in muscle induced by triiodothyronine; the role of glucose-1,6-bisphosphate. Biochem Mol Med 56: 19-25
3. Ganote CE, Seabra-Gomes R, Nayler WG, Jennings RB (1975) Irreversible myocardial injury in anoxic perfused rat hearts. Am J Pathol 80: 419-450
4. Grofte T, Wolthers T, Moller N et al. (1997) Moderate hyperthyroidism reduces liver amino nitrogen conversion, muscle nitrogen contents and overall nitrogen balance in rats. Eur Journal Clin Invest 27: 85-92
5. Hearse DJ, Garlick PB, Humphrey SM (1977) Ischaemic contracture of the myocardium: mechanisms and prevention. Am J Cardiol 39: 986-993
6. Hoh JFY, Egerton JL (1979) Action of triiodothyronine on the synthesis of rat ventricular myosin isoenzymes. FEBS Lett 101: 143-146
7. Humphrey SM, Gavin JB, Herdson PB (1980) The relationship of ischaemic contracture to vascular reperfusion in the isolated rat heart. J Mol Cell Cardiol 12: 1397-1406
8. Hyatt PY (1990) Experimental models. Research in Cardiac Hypertrophy and Failure. In: Swynghedauw B (ed) INSERM/John Libbey Eurotext, pp 13-22
9. Katz AM, Tada M (1972) The stone heart: a challenge to biochemist. Am J Cardiol 29: 578-580
10. Kingsley PB, Sako EY, Young MQ, Zimmer SD, Ugurbil K, Foker JE, From AH (1991) Ischaemic contracture begins when anaerobic glycolysis stops: a 31P-NMR study of isolated rat hearts. Am J Physiol 261: H469-H478
11. Kolocassides KG, Galinanes M, Hearse DJ (1996) Dichotomy of ischaemic preconditioning. Improved postischaemic contractile function despite intensification of ischaemic contracture. Circulation 93: 1725-1733
12. Murry CE, Jennings RB, Reimer KA (1986) Preconditioning with ischaemia: a delay of lethal cell injury in ischaemic myocardium. Circulation 74: 1124-36
13. Pantos CI, Davos CH, Carageorgiou HC, Varonos DV, Cokkinos DV (1996) Ischaemic preconditioning protects against myocardial dysfunction caused by ischaemia in isolated hypertrophied rat hearts. Basic Res Cardiol 91: 444-449
14. Riva E, Hearse DJ (1993) Age-dependent changes in myocardial susceptibility to ischaemic injury. Cardioscience 4: 85-92
15. Owen P, Dennis S, Opie LH (1990) Glucose flux rate regulates onset of ischaemic contracture in globally underperfused rat hearts. Circ Res 66: 344-354
16. Shaefer S, Carr LJ, Prussel E, Ramasamy R (1995) Effects of glycogen depletion of ischaemic injury in isolated rat hearts: insights into preconditioning. Am J Physiol 268: H935-H944
17. Soares RP, de Albuquerque CP, Chacko VP, Gerstenblith G, Weiss RG (1997) Role of preischaemic glycogen depletion in the improvement of postischaemic metabolic and contractile recovery of ischaemia-preconditioned rat hearts. Circulation 96: 975-983
18. Speechly-Dick ME, Baxter GF, Yellon DM (1994) Ischaemic preconditioning protects hypertrophied myocardium. Cardiovasc Res 28: 1025-1029
19. Steenbergen C, Murphy E, Watts JA, London RE (1990) Correlation between cytosolic free calcium, contracture, ATP and irreversible ischaemic injury in perfused rat heart. Circ Res 66: 135-146
20. Tatsumi T, Motaba S, Kobara M, Keira N, Kawahara A, Tsuruyama K et al. (1998) Energy metabolism after ischaemic preconditioning in streptozotocin-induced diabetic rat hearts. J Am Coll Cardiol 31: 707-15
21. Van der Vusse GJ, Coumans WA, Ulrich M, Van Bilsen M (1998) Thyroxine induced alteration in cardiac energy metabolism. J Mol Cell Cardiol 30: A110
22. Ventura-Clapier R, Veksler V (1994) Myocardial ischaemic contracture: metabolites affect rigor tension development and stiffness. Circ Res 74: 920-929
23. Volovsek A, Subramanian R, Reboussin D (1992) Effects of duration of ischaemia during preconditioning on mechanical function, enzyme release and energy production in the isolated working rat heart. J Mol Cell Cardiol 24: 1011-1019
24. Wolfe Cl, Sievers RE, Visseren FLJ, Donnelly TJ (1993) Loss of myocardial protection after preconditioning correlates with the time course of glycogen recovery within the preconditioned segment. Circulation 87: 881-892