Localization of fibroblast growth factor-2 (basic FGF) and FGF receptor- 1 in adult human kidney

Kidney International

Volumn 56, Issue 3, 1999, Pages 883-897

  Floege, Jürgen ^a,b,c   Hudkins, Kelly L ^a,b,c   Eitner, Frank ^a,b,c   Cui, Yan ^a,b,c   Morrison, Richard S ^a,b,c   Schelling, Margaret A ^a,b,c   Alpers, Charles E ^a,b,c,d  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^c WASHINGTON STATE UNIVERSITY   (United States)

^d UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Arteries; Growth factor receptors; Renal tubule; Smooth muscle cells

Indexed keywords

FIBROBLAST GROWTH FACTOR 1; FIBROBLAST GROWTH FACTOR 2; FIBROBLAST GROWTH FACTOR RECEPTOR; GROWTH FACTOR RECEPTOR;

ANTIBODY SPECIFICITY; ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN TISSUE; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; KIDNEY DISEASE; KIDNEY TUBULE; PATHOPHYSIOLOGY; PRIORITY JOURNAL;

EID: 0032846569     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1755.1999.00637.x     Document Type: Article

References (52)

1. 1. Baird A: Potential mechanisms regulating the extracellular activities of basic fibroblast growth factor (FGF-2). Mol Reprod Dev 39:43-48, 1994
2. 2. Bauters C: Growth factors as a potential new treatment for ischemic heart disease. Clin Cardiol 20 (11 Suppl 2):II-52-II-57, 1997
3. 3. Coutts JC, Gallagher JT: Receptors for fibroblast growth factors. Immunol Cell Biol 73:584-589, 1995
4. 4. Gospodarowicz D: Biological activities of fibroblast growth factors. Ann NY Acad Sci 638:1-8, 1991
5. 5. Klagsbrun M: Mediators of angiogenesis: The biological significance of basic fibroblast growth factor (bFGF)-heparin and heparan sulfate interactions. Semin Cancer Biol 3:81-87, 1992
6. 6. Mendley SR, Toback FG: Autocrine and paracrine regulation of kidney epithelial cell growth. Annu Rev Physiol 51:33-50, 1989
7. 7. Floege J, Burg M, Hugo C, Gordon KL, Van Goor H, Reidy M, Couser WG, Koch KM, Johnson RJ: Endogenous fibroblast growth factor-2 mediates cytotoxicity in experimental mesangio-proliferative glomerulonephritis. J Am Soc Nephrol 9:792-801, 1998
8. 8. Floege J, Kriz W, Schulze M, Susani M, Kerjaschki D, Mooney A, Couser WG, Koch KM: Basic fibroblast growth factor augments podocyte injury and induces glomerulosclerosis in rats with experimental membranous nephropathy. J Clin Invest 96:2809-2819, 1995
9. 9. Shankland SJ, Floege J, Thomas SE, Nangaku M, Hugo C, Pippin J, Henne K, Hockenberry DM, Johnson RJ, Couser WG: Cyclin kinase inhibitors are increased during experimental membranous nephropathy: Potential role in limiting glomerular epithelial cell proliferation in vivo. Kidney Int 52:404-413, 1997
10. 10. Floege J, Eng E, Young BA, Alpers CE, Barrett TB, Bowen-Pope DF, Johnson RJ: Infusion of platelet-derived growth factor or basic fibroblast growth factor induces selective glomerular mesangial cell proliferation and matrix accumulation in rats. J Clin Invest 92:2952-2962, 1993
11. 11. Floege J, Eng E, Lindner V, Alpers CE, Young BA, Reidy MA, Johnson RJ: Rat glomerular mesangial cells synthesize basic fibroblast growth factor: Release, upregulated synthesis, and mitogenicity in mesangial proliferative glomerulonephritis. J Clin Invest 90:2362-2369, 1992
12. 12. Francki A, Uciechowski P, Floege J, Von Der Ohe J, Resch K, Radeke HH: Autocrine growth regulation of human glomerular mesangial cells is primarily mediated by basic fibroblast growth factor. Am J Pathol 147:1372-1382, 1995
13. 13. Ballermann BJ: Regulation of bovine glomerular endothelial cell growth in vitro. Am J Physiol 256:C182-C189, 1989
14. 14. Takeuchi A, Yoshizawa N, Yamamoto M, Sawasaki Y, Oda T, Senoo A, Niwa H, Fuse Y: Basic fibroblast growth factor promotes proliferation of rat glomerular visceral epithelial cells in vitro. Am J Pathol 141:107-116, 1992
15. 15. Ray PE, Bruggeman LA, Weeks BS, Kopp JB, Bryant JL, Owens JW, Notkins AL, Klotman PE: bFGF and its low affinity receptors in the pathogenesis of HIV-associated nephropathy in transgenic mice. Kidney Int 46:759-772, 1994
16. 16. Maciag T, Zhan X, Garfinkel S, Friedman S, Prudovsky I, Jackson A, Wessendorf J, Hu X, Gamble S, Shi J, Brown S, Taratini F, Zimrin A: Novel mechanisms of fibroblast growth factor 1 function. Recent Prog Horm Res 49:105-123, 1994
17. 17. Ruoslahti E, Yamaguchi Y: Proteoglycans as modulators of growth factor activities. Cell 64:867-869, 1991
18. 18. Johnson DE, Williams LT: Structural and functional diversity in the FGF receptor multigene family. Adv Cancer Res 60:1-41, 1993
19. 19. Partanen J, Makela TP, Eerola E, Korhonen J, Hirvonen H, Claesson-Welsh L, Alitalo K: FGFR-4, a novel acidic fibroblast growth factor receptor with a distinct expression pattern. EMBO J 10:1347-1354, 1991
20. 20. Ron D, Reich R, Chedid M, Lengel C, Cohen OE, Chan AM, Neufeld G, Miki T, Tronick SR: Fibroblast growth factor receptor 4 is a high affinity receptor for both acidic and basic fibroblast growth factor but not for keratinocyte growth factor. J Biol Chem 268:5388-5394, 1993
21. 21. Schulze-Osthoff K, Risau W, Vollmer E, Sorg C: In situ detection of basic fibroblast growth factor by highly specific antibodies. Am J Pathol 137:85-92, 1990
22. 22. Cordon-Cardo C, Vlodavsky I, Haimovitz-Friedman A, Hicklin D, Fuks Z. Expression of basic fibroblast growth factor in normal human tissues. Lab Invest 63:832-840, 1990
23. 23. Hughes SE, Hall PA: Immunolocalization of fibroblast growth factor receptor 1 and its ligands in human tissues. Lab Invest 69:173-182, 1993
24. 24. Nanus DM, Schmitz-Drager BJ, Motzer RJ, Lee AC, Vlamis V, Cordon-Cardo C, Albino AP, Reuter VE: Expression of basic fibroblast growth factor in primary human renal tumors: Correlation with poor survival. J Natl Cancer Inst 85:1597-1599, 1993
25. 25. Stein-Oakley AN, Maguire JA, Dowling J, Perry G, Thomsom NM: Altered expression of fibrogenic growth factors in IgA nephropathy and focal and segmental glomerulosclerosis. Kidney Int 51:195-204, 1997
26. 26. Kerby JD, Verran DJ, Luo KL, Ding Q, Tagouri Y, Herrera GA, Diethelm AG, Thompson JA: Immunolocalization of FGF-1 and receptors in human renal allograft vasculopathy associated with chronic rejection. Transplantation 62:467-475, 1996
27. 27. Kerby JD, Luo KL, Ding Q, Tagouri Y, Herrera GA, Diethelm AG, Thompson JA: Immunolocalization of acidic fibroblast growth factor and receptors in the tubulointerstitial compartment of chronically rejected human renal allografts. Transplantation 63:988-995, 1997
28. 28. Kerby JD, Verran DJ, Luo KL, Ding Q, Tagouri Y, Herrera GA, Diethelm AG, Thompson JA: Immunolocalization of FGF-1 and receptors in glomerular lesions associated with chronic human renal allograft rejection. Transplantation 62:190-200, 1996
29. 29. Alpers CE, Seifert RA, Hudkins KL, Johnson RJ, Bowen-Pope DF: Developmental patterns of PDGF B-chain, PDGF-receptor, and alpha-actin expression in human glomerulogenesis. Kidney Int 42:390-399, 1992
30. 30. Venkateswaran S, Blanckaert V, Schelling M: Production of anti-fibroblast growth factor receptor monoclonal antibodies by in vitro immunization. Hybridoma 11:729-739, 1992
31. 31. Quitadamo IJ, Schelling ME: Efficient purification of mouse anti-FGF receptor IgM monoclonal antibody by magnetic beads. Hybridoma 17:199-207, 1998
32. 32. Alpers CE, Davis CL, Barr D, Marsh CL, Hudkins KL: Identification of platelet-derived growth factor A and B chains in human renal vascular rejection. Am J Pathol 148:439-451, 1996
33. 33. Floege J, Hudkins KL, Seifert RA, Francki A, Bowen-Pope DF, Alpers CE: Localization of PDGF alpha-receptor in the developing and mature human kidney. Kidney Int 51:1140-1150, 1997
34. 34. Li Y, Koga M, Kasayama S, Matsumoto K, Arita N, Hayakawa T, Sato B: Identification and characterization of high molecular weight forms of basic fibroblast growth factor in human pituitary adenomas. J Clin Endocrinol Metab 75:1436-1441, 1992
35. 35. Eckenstein FP, Shipley GD, Nishi R: Acidic and basic fibroblast growth factors in the nervous system: Distribution and differential alteration of levels after injury of central versus peripheral nerve. J Neuroscience 11:412-419, 1991
36. 36. Cauchi J, Alcorn D, Cancilla B, Key B, Berka JL, Nurcombe V, Ryan GB, Bertram JF: Light-microscopic immunolocalization of fibroblast growth factor-1 and -2 in adult rat kidney. Cell Tissue Res 285:179-187, 1996
37. 37. Morita H, Shinzato T, David G, Mizutani A, Habuchi H, Fujita Y, Ito M, Asai J, Maeda K, Kimata K: Basic fibroblast growth factor-binding domain of heparan sulfate in the human glomerulosclerosis and renal tubulointerstitial fibrosis. Lab Invest 71:528-535, 1994
38. 38. Alpers CE, Seifert RA, Hudkins KL, Johnson RJ, Bowen-Pope DF: PDGF-receptor localizes to mesangial, parietal epithelial, and interstitial cells in human and primate kidneys. Kidney Int 43:286-294, 1993
39. 39. Alpers CE, Hudkins KL, Ferguson M, Johnson RJ, Rutledge JC: Platelet-derived growth factor A-chain expression in developing and mature human kidneys and in Wilms' tumor. Kidney Int 48:146-154, 1995
40. 40. Healy AM, Herman IM: Density-dependent accumulation of basic fibroblast growth factor in the subendothetial matrix. Eur J Cell Biol 59:56-67, 1992
41. 41. Hanneken A, Baird A: Immunolocalization of basic fibroblast growth factor: Dependence on antibody type and tissue fixation. Exp Eye Res 54:1011-1014, 1992
42. 42. Kardami E, Murphy LJ, Liu L, Padua RR, Fandrich RR: Characterization of two preparations of antibodies to basic fibroblast growth factor which exhibit distinct patterns of immunolocalization. Growth Factors 4:69-80, 1990
43. 43. Baird A, Walicke PA: Fibroblast growth factors. Br Med Bull 45:438-452, 1989
44. 44. Ford MD, Cauchi J, Greferath U, Bertram JF: Expression of fibroblast growth factors and their receptors in rat glomeruli. Kidney Int 51:1729-1738, 1997
45. 45. Mazue G, Newman AJ, Scampini G, Della Torre P, Hard GC, Iatropoulos MJ, Williams GM, Bagnasco SM: The histopathology of kidney changes in rats and monkeys following intravenous administration of massive doses of FCE 26184, human basic fibroblast growth factor. Toxicol Pathol 21:490-501, 1993
46. 46. Kanda S, Hisamatsu H, Igawa T, Eguchi J, Taide M, Sakai H, Kanetake H, Saito Y, Yoshitake Y, Nishikawa K: Peritubular endothelial cell proliferation in mice during compensatory renal growth after unilateral nephrectomy. Am J Physiol 265:F712-F716, 1993
47. 47. Miskell CA, Simpson DP: Hyperplasia precedes increased glomerular filtration rate in rat remnant kidney. Kidney Int 37:758-766, 1990
48. 48. Xin X, Johnson AD, Scott-Burden T, Engler D, Casscells W: The predominant form of fibroblast growth factor receptor expressed by proliferating human arterial smooth muscle cells in culture is type 1. Biochem Biophys Res Commun 204:557-564, 1994
49. 49. Lindner V, Reidy MA: Proliferation of smooth muscle cells after vascular injury is inhibited by an antibody against basic fibroblast growth factor. Proc Natl Acad Sci USA 88:3739-3743, 1991
50. 50. Lindner V, Olson NE, Clowes AW, Reidy MA: Inhibition of smooth muscle cell proliferation in injured rat arteries: Interaction of heparin with basic fibroblast growth factor. J Clin Invest 90:2044-2049, 1992
51. 51. Villaschi S, Nicosia RF: Angiogenic role of endogenous basic fibroblast growth factor released by rat aorta after injury. Am J Pathol 143:181-190, 1993
52. 52. Lindner V, Majack RA, Reidy MA: Basic fibroblast growth factor stimulates endothelial regrowth and proliferation in denuded arteries. J Clin Invest 85:2004-2008, 1990