Selective detection of inactivating mutations of the tumor suppressor gene p53 in bladder tumors

Journal of Urology

Volumn 161, Issue 6, 1999, Pages 1973-1975

  Pfister, Christian ^a   Flaman, Jean Michel ^b   Martin, Cosette ^b   Grise, Philippe ^b   Frebourg, Thierry ^b  

^a ROUEN UNIVERSITY HOSPITAL   (France)

^b NONE

Author keywords

Bladder carcinoma; Functional assay; P53 mutation

Indexed keywords

ARTICLE; BLADDER TUMOR; CARCINOGENESIS; GENE INACTIVATION; GENE MUTATION; GENE OVEREXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; NONSENSE MUTATION; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE;

EID: 0032845610     PISSN: 00225347     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-5347(05)68866-0     Document Type: Article

References (20)

1. Heney, N. M., Ahmed, S., Flanagan, M. J., Frable, W., Corder, M. P., Hafermann, M. D. and Hawkins, I. R. for National Bladder Cancer Collaborative Group A: Superficial bladder cancer: progression and recurrence. J. Urol., 130: 1083, 1983.
2. Tetu, B., Allard, P., Fradet, Y., Roberge, N. and Bernard, P.: Prognostic significance of nuclear DNA content and S phase fraction by flow cytometry in primary papillary superficial bladder cancer. Hum. Pathol., 27: 922, 1996.
3. Allard, P., Fradet, Y., Tetu, B. and Bernard, P.: Tumor-associated antigens as prognostic factors for recurrence in 382 patients with primary transitional cell carcinoma of the bladder. Clin. Cancer Res., 1: 1195, 1995.
4. Sarkis, A., Dalbagni, G., Cordon-Cardo, C., Zhang, Z. F., Sheinfeld, J., Fair, W. R. and Reuter, V. E.: Nuclear overexpression of p53 protein in transitional cell bladder carcinoma: a marker for disease progression. J. Natl. Cancer Inst., 85: 53, 1993.
5. Esrig, D., Elmajian, D., Groshen, S., Freeman, J. A., Stein, J. P., Chen, S. C., Nichols, P. W., Skinner, D. G., Jones, P. A. and Cote, R. J.: Accumulation of nuclear p53 and tumor progression in bladder cancer. N. Engl. J. Med., 331: 1259, 1994.
6. International Union Against Cancer.: Cancer UUIC1 TNM, Classification of Malignant Tumours. Geneva, Switzerland: International Union Against Cancer, 1992.
7. Carbin, R. E., Ekman, P., Gustafson, H., Christensen, N. J., Silfversward, C. and Sandstedt, B.: Grading of human urothelial carcinoma based on nuclear atypia and mitotic frequency. II. Prognostic importance. J. Urol., 145: 972, 1991.
8. Flaman, J. M., Frebourg, T., Moreau, V., Charbonnier, F., Martin, C., Chappuis, P., Sappino, A. P., Limacher, J. M., Bron, L., Benhattar, J., Tada, M., Van Meir, E. G., Estreicher, A. and Iggo, R. D.: A simple p53 functional assay for screening cell lines, blood and tumors. Proc. Natl. Acad. Sci. USA, 92: 3963, 1995.
9. Frebourg, T., Flaman, J-M., Estreicher, A. and Iggo, R. D.: Functional assay of the p53 tumour suppressor gene. In: Mutation Detection: A Practical Approach, Edited by R. G. H. Cotton, E. Edkins and S. M. Forrest, Oxford: Oxford University Press, pp. 211-22, 1998.
10. Ishioka, C., Frebourg, T., Yan, Y. X., Vidal, M., Friend, S. H., Schmidt, S. and Iggo, R.: Screening patients for heterozygous p53 mutations using a functional assay in yeast. Nat. Genet., 5: 124, 1993.
11. Waridel, F., Estreicher, A., Bron, L., Flaman, J. M., Fontolliet, C., Monnier, P., Vannier, A., Frebourg, T. and Iggo, R.: Field cancerisation and polyclonal p53 mutation in the upper aerodigestive tract. Oncogene, 14: 163, 1997.
12. Malmström, P. U., Busch, C. and Norlen, B. J.: Recurrence, progression and survival in bladder cancer. Scand. J. Urol. Nephrol., 21: 185, 1987.
13. Kaye, K. W. and Lange, P.: Mode of presentation of invasive bladder cancer. Reassessment of the problem. J. Urol., 128: 31, 1982.
14. Jakse, G., Loidl, W., Seeber, G. and Hofstadter, F.: Stage T1, grade 3 transitional carcinoma of the bladder: an unfavorable tumor? J. Urol., 137: 39, 1987.
15. Pfister, C., Buzelin, F., Casse, C., Gaschignard, N., Buzelin, J. M. and Bouchot, O.: Comparative analysis of MiB1 and p53 expression in human bladder tumors and their correlation with cancer progression. Eur. Urol., 33: 278, 1998.
16. Vogelstein, B. and Kinzler, K.: p53 function and dysfunction. Cell, 70: 523, 1992.
17. Tetu, B., Fradet, Y., Allard, P., Veilleux, C., Roberge, N. and Bernard, P.: Prevalence and clinical significance of HER-2/ neu, p53 and Rb expression in primary superficial bladder cancer. J. Urol., 155: 1784, 1996.
18. Mosch, H., Sauter, G., Mitatsch, M. J., Guadat, F., Epper, R. and Waldman, F. M.: p53 but not erbB-2 expression is associated with rapid tumor proliferation in urinary bladder cancer. Hum. Pathol., 25: 1346, 1994.
19. Sarkis, A. S., Dalgani, G., Cordon-Cardo, C., Melamed, J., Zhang, Z. F., Sheinfeld, J., Fair, W. R., Herr, H. W. and Reuter, V. E.: Association of p53 nuclear overexpression and tumor progression in carcinoma in situ of the bladder. J. Urol., 152: 388, 1994.
20. Raitanen, M. P., Tammela, T. L., Kallioinen, M. and Isola, J.: p53 accumulation, desoxy-ribonucleic acid ploidy and progression of bladder cancer. J. Urol., 157: 1250, 1997.