Comparison of the novel antipsychotic ziprasidone with clozapine and olanzapine: Inhibition of dorsal raphe cell firing and the role of 5-HT(1A) receptor activation

Neuropsychopharmacology

Volumn 21, Issue 5, 1999, Pages 622-631

  Sprouse, Jeffrey S ^a   Reynolds, Linda S ^a   Braselton, John P ^a   Rollema, Hans ^a   Zorn, Stevin H ^a  

^a PFIZER INC   (United States)

Author keywords

5 HT(1A) Agonist; Antipsychotic; Dorsal raphe nucleus; Electrophysiology

Indexed keywords

CLOZAPINE; DESIPRAMINE; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; NEUROLEPTIC AGENT; NORADRENALIN UPTAKE INHIBITOR; OLANZAPINE; SEROTONIN 1A ANTAGONIST; SEROTONIN 1A RECEPTOR; ZIPRASIDONE;

ANIMAL CELL; ARTICLE; BRAIN ELECTROPHYSIOLOGY; DORSAL RAPHE NUCLEUS; DOSE RESPONSE; DRUG EFFECT; DRUG MECHANISM; DRUG RECEPTOR BINDING; DRUG STRUCTURE; ELECTROPHYSIOLOGY; INTRAVENOUS DRUG ADMINISTRATION; MALE; NERVE CELL INHIBITION; NONHUMAN; PRIORITY JOURNAL; RAT; SEROTONINERGIC NERVE CELL;

ACTION POTENTIALS; ADRENERGIC UPTAKE INHIBITORS; ANIMALS; BENZODIAZEPINES; CLOZAPINE; DESIPRAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; MALE; NEURONS; PIPERAZINES; PIRENZEPINE; PYRIDINES; RAPHE NUCLEI; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, SEROTONIN; RECEPTORS, SEROTONIN, 5-HT1; SEROTONIN AGONISTS; SEROTONIN ANTAGONISTS; SEROTONIN UPTAKE INHIBITORS; THIAZOLES;

EID: 0032845187     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0893-133X(99)00057-3     Document Type: Article

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