Cefoperazone prevents the inactivation of α1-antitrypsin by activated neutrophils

Antimicrobial Agents and Chemotherapy

Volumn 43, Issue 9, 1999, Pages 2307-2310

  Dallegri, Franco ^a,b   Dapino, Patrizia ^b   Arduino, Nicoletta ^b   Bertolotto, Maria ^b   Ottonello, Luciano ^b  

^a UNIVERSITY OF GENOA   (Italy)

^b UNIVERSITY OF GENOA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 1 ANTITRYPSIN; ANTIBIOTIC AGENT; CEFOPERAZONE; CEFOTAXIME; CEFTAZIDIME; ELASTASE INHIBITOR; HYPOCHLOROUS ACID; LEUKOCYTE ELASTASE; OFLOXACIN; PANCREATIC ELASTASE; RIFAMPICIN; TOBRAMYCIN;

ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME INACTIVATION; HUMAN; HUMAN CELL; INFLAMMATION; LEUKOCYTE ACTIVATION; NEUTROPHIL; PRIORITY JOURNAL; TISSUE INJURY;

EID: 0032844714     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/aac.43.9.2307     Document Type: Article

References (34)

1. 1-antichymotrypsin by neutrophils in arthritic joints. Arthritis Rheum. 36:158-180.
2. Cantin, A., and D. E. Woods. 1993. Protection by antibiotics against myeloperoxidase-dependent cytotoxicity to lung epithelial cells in vitro. J. Clin. Investig. 91:38-45.
3. Carreer, R., G. Deby-Dupont, C. Deby, L. Jadoul, and M. Mathy. 1998. Oxidant-scavenging activities of beta-lactam agents. Eur. J. Clin. Microbiol. Infect. Dis. 17:43-46.
4. Carrell, R. W. 1986. Alpha-1-antitrypsin: molecular pathology, leukocytes and tissue damage. J. Clin. Investig. 78:1427-1431.
5. 1-protease inhibitor by human neutrophils. J. Biol. Chem. 256:3348-3353.
6. Dallegri, F., A. Ballestrero, G. Frumento, and F. Patrone. 1987. Augmentation of neutrophil-mediated erythrocyte lysis by cells derived in vitro from human monocytes. Blood 70:1743-1749.
7. Dallegri, F., L. Ottonello, P. Dapino, and C. Sacchetti. 1992. Effect of nonsteroidal antiinflammatory drugs on the neutrophil promoted inactivation of alpha-1-proteinase inhibitor. J. Rheumatol. 19:419-423.
8. Dallegri, F., and L. Ottonello. 1997. Tissue injury in neutrophilic inflammation. Inflamm. Res. 46:383-391.
9. Doherty, J. B., B. M. Ashe, L. W. Argenbright, P. L. Barker, R. J. Bonney, G. O. Chandler, M. E. Dalghren, C. P. Dorn, Jr., P. E. Finke, R. A. Firestone, D. Fletcher, W. K. Hagmann, R. Munford, L. O'Grady, A. L. Maycock, J. M. Pisano, S. K. Shah, K. R. Thompson, and M. Zimmerman. 1986. Cephalosporin antibiotics can be modified to inhibit human leukocyte elastase. Nature 322:192-194.
10. Gallin, J. I., I. M. Goldstein, and R. Snyderman. 1992. Inflammation. Basic principles and clinical correlates, 2nd ed. Raven Press, New York, N.Y.
11. Gunther, M. R., J. Mao, and M. S. Cohen. 1993. Oxidant-scavenging activities of ampicillin and sulbactam and their effects on neutrophil functions. Antimicrob. Agents Chemother. 37:950-956.
12. Henson, P. M., and R. B. Johnston, Jr. 1987. Tissue injury in inflammation: oxidants, proteinases, and cationic proteins. J. Clin. Investig. 79:669-674.
13. Kemmerich, B., H. Lode, G. Belmega, T. Jendroschek, K. Borner, and P. Koeppe. 1983. Comparative pharmacokinetics of cefoperazone, cefotaxime, and moxalactam. Antimicrob. Agents Chemother. 23:429-434.
14. Knight, W. B., A. L. Maycock, B. G. Green, B. M. Ashe, P. Gale, H. Weston, P. E. Finke, W. K. Hagmann, S. K. Shah, and J. B. Doberty. 1992. Mechanism of inhibition of human leukocyte elastase by two cephalosporin derivatives. Biochemistry 31:4980-4986.
15. Labro, M. T., J. El Benna, N. Charlier, H. Abdelghaffar, and J. Hakin. 1994. Cefdinir (CI-983), a new oral amino-2-thiazolyl cephalosporin, inhibits human neutrophil myeloperoxidase in the extracellular medium but not the phagolysosome. J. Immunol. 152:2447-2455.
16. Laemmli, U. K. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685.
17. Lapenna, D., L. Cellini, S. De Gioia, A. Mezzetti, G. Ciofani, D. Festi, and F. Cuccurullo. 1995. Cephalosporins are scavengers of hypochlorous acid. Biochem. Pharmacol. 49:1249-1254.
18. Malech, H. L., and J. I. Gallin. 1987. Neutrophils in human diseases. N. Engl. J. Med. 317:687-694.
19. Ossanna, P. J., S. T. Test, N. R. Matheson, S. Regiani, and S. Weiss. 1986. Oxidative regulation of neutrophil elastase-alpha-1-proteinase inhibitor interaction. J. Clin. Investig. 77:1939-1951.
20. Ottonello, L., F. Dallegri, P. Dapino, G. Pastorino, and C. Sacchetti. 1991. Cytoprotection against neutrophil-delivered oxidant attack by antibiotics. Biochem. Pharmacol. 42:2317-2321.
21. 1-proteinase inhibitor from the neutrophil oxidative inactivation. Digestion 51:140-145.
22. Ottonello, L., P. Dapino, M. C. Scirocco, A. Balbi, M. Bevilacqua, and F. Dallegri. 1994. Sulphonamides as anti-inflammatory agents: old drugs for new therapeutic strategies in neutrophilic inflammation? Clin. Sci. 88:331-336.
23. Srinivasan, S., E. L. Francke, and H. C. Neu. 1981. Comparative pharmacokinetics of cefoperazone and cefamandole. Antimicrob. Agents Chemother. 19:298-301.
24. Styrt, B. 1989. The role of phagocytes in non-infectious diseases, p. 145-169. In M. S. Klempner, B. Styrt, and J. Ho (ed.), Phagocytes and disease. Kluwer Academic Publishers, Dordrecht, The Netherlands.
25. Styrt, B., J. Ho, and M. S. Klempner. 1989. Interactions between antimicrobial agents and phagocytes, p. 119-144. In M. S. Klempner, B. Styrt, and J. Ho (ed.), Phagocytes and disease. Kluwer Academic Publishers, Dordrecht, The Netherlands.
26. Swaim, M. W., and S. V. Pizzo. 1988. Methionine sulfoxide and the oxidative regulation of plasma proteinase inhibitors. J. Leukoc. Biol. 43:365-379.
27. Test, S. T., and S. J. Weiss. 1986. The generation and utilization of chlorinated oxidants by human neutrophils. Adv. Free Radic. Biol. Med. 2:91-116.
28. Thomas, E. L., M. M. Jefferson, and M. B. Grisham. 1982. Myeloperoxidase-catalyzed incorporation of amines into proteins: role of hypochlorous acid and dichloramines. Biochemistry 21:6299-6308.
29. 1-proteinase inhibitor by alveolar inflammatory cells from smoking patients with or without emphysema. Am. Rev. Respir. Dis. 147:1537-1543.
30. Wartenberg, K., J. Tonak, and W. Knapp. 1983. Lung tissue concentrations of cefoperazone. Infection 11:280-282.
31. Wasil, M., B. Halliwell, C. P. Moorhouse, C. Duncan, S. Huthinson, and H. Baum. 1987. Biologically-significant scavenging of the myeloperoxidase-derived oxidant hypochlorous acid by some anti-inflammatory drugs. Biochem. Pharmacol. 36:3847-3850.
32. Weiss, S. J. 1989. Tissue destruction by neutrophils. N. Engl. J. Med. 320: 565-576.
33. Weiss, S. J., R. Klein, A. Slivka, and M. Wei. 1982. Chlorination of taurine by human neutrophils. Evidence for hypochlorous acid generation. J. Clin. Investig. 70:588-607.
34. Wong, P. S., and J. Travis. 1980. Isolation and properties of oxidized alpha-1-proteinase inhibitor from human rheumatoid synovial fluid. Biochem. Biophys. Res. Commun. 96:1449-1454.