Arterial relaxation mediated by endothelium-derived hyperpolarizing factor in hypertension induced by chronic inhibition of nitric oxide synthesis

Clinical and Experimental Hypertension

Volumn 21, Issue 7, 1999, Pages 1203-1221

  Kimura, K ^a   Tsuda, K ^a   Sasajima, H ^a   Shiotani, M ^a   Baba, A ^a   Hano, T ^a   Nishio, I ^a  

^a WAKAYAMA MEDICAL UNIVERSITY   (Japan)

Author keywords

Apamin; Experimental hypertension; L NAME; Mesenteric artery; Nitric oxide; Nitroprusside; Potassium channels

Indexed keywords

ENDOTHELIUM DERIVED HYPERPOLARIZING FACTOR; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERY DILATATION; ARTERY TONE; ARTICLE; CONTROLLED STUDY; ENZYME INHIBITION; HUMAN; HYPERTENSION; MALE; RAT; SMOOTH MUSCLE RELAXATION; VASCULAR SMOOTH MUSCLE;

EID: 0032843764     PISSN: 10641963     EISSN: None     Source Type: Journal    
DOI: 10.3109/10641969909052198     Document Type: Article

References (40)

1. Furchgott RF, Vanhoute PM. Endothelium-derived relaxing and contracting factors. FASEB J 1989;3:2007-2018.
2. Yanagisawa M, Kurihara H, Kimura S, Tomobe Y, Kobayashi M, Mitsui Y, Yazaki Y, Goto K, Masaki T. A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature 1988;332:441-415.
3. Dzau VJ. Vascular wall renin-angiotensin pathway in control of the circulation. Am J Med 1984;77:31-36.
4. Furchgott RF, Zawadzki JV: The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature 1980;288:373-376.
5. Palmer RMJ, Ferrige AG, Moncada S. Nitric oxide accounts for the biological activity of endothelium-derived relaxing factor. Nature 1987;327:524-526.
6. Förstermann U, Mulsch A, Bohme E and Busse R. Stimulation of soluble guanylate cyclase by an acetylcholine-induced endothelium-derived factor from rabbit and canine arteries. Circ Res 1986;58:531-538.
7. Komori K, Vanhoute PM. Endothelium-derived hyperpolarizing factor. Blood vessels 1990;260:238-245.
8. Chen G, Yamamoto Y, Miwa K, Suzuki H. Hyperpolarization of arterial smooth muscle induced by endothelial humoral substances. Am J Physiol 1991;260:H1888-1892.
9. Brayden JE, Quayle JM, Standen NB, Nelson MT. Role of potassium channels in the vascular response to endogenous and pharmacological vasodilators. Blood vessels 1991;28:147-153.
10. Rees DD, Palmer RMJ, Moncada S. Role of endothelium-derived nitric oxide in regulation of blood pressure. Proc Natl Acad Sci USA 1989;86:3375-3378.
11. Rees DD, Palmer RMJ, Schultz R, Hodson HF, Moncada S. Characterization of three inhibitors of endothelial nitric oxide synthase in vitro and in vivo. Br J Pharmacol 1990;101:746-752.
12. Meyer P, Flammer J, Lüschner T. Local action of the renin angiotensin system in the porcine ophthalmic circulation: effects of ACE-inhibitors and angiotensin receptor antagonists. Invest Ophthalmol Vis Sci 1995;36:555-562.
13. Gardiner S, Kemp P, Bennett T, Palmer R, Moncada S. Nitric oxide synthase inhibitors cause sustained, but reversible, hypertension and hindquarters vasoconstriction in Brattleboro rats. Eur J Pharmacol 1992;213:449-451.
14. Gardiner S, Champton A, Bennett T, Palmer R, Moncada S. Control of regional blood flow by endothelium-derived nitric oxide. Hypertension 1990;15:486-492.
15. Ribeiro MO, Antunes E, de Nucci G, Lovisolo SM, Zatz R. Chronic inhibition of nitric oxide synthesis: a new model of arterial hypertension. Hypertension 1992;20:298-303.
16. Chen G, Suzuki H, Weston AH. Acetylcholine release endothelium-derived hyperpolarizing factor and EDRF from rat blood vessels. Br J Pharmacol 1988;95:1165-1174.
17. +-channels open by cromakalim, acetylcholine and substance P in rat aorta and porcine coronary artery. Br J Pharmacol 1991;102:585-594.
18. + channel in arterial smooth muscle. Science 1989;245:177-180.
19. Edwards G, Weston AH. Potassium channel openers and vascular smooth muscle relaxation. Pharmacol Ther 1990;48:237-258.
20. Parkington HC, Tare M, Tonta MA, Coleman HA. Stretch revealed three components in the hyperpolarization of guinea-pig coronary artery in response to acetylcholine. J Physiol 1993;465:459-476.
21. Corriu C, Félétou M, Canet E, Vanhoutte P. Endothelium-derived factors and hyperpolarization of the carotid artery of the guinea-pig. Br J Pharmacol 1996;119:959-964.
22. Waldron GJ, Garland CJ. Effects of potassium channel blockers on L-NAME insensitive relaxations in rat small mesenteric artery. Can J Physiol Pharmacol 1994;72(suppl 1):115.
23. Mökynene H, Kähönen M, Wu X, Arvola P, Prösti I. Endothelial function in deoxycorticosterone-NaCl hypertension: effects of calcium supplementation. Circulation 1996;93:1000-1008.
24. +]: a functional approach to separating EDHF-and EDNO-related mechanism in perfused rat mesenteric arterial bed. J Cardiovasc Pharmacol 1993;21:423-429.
25. + channels mediate an endothelium-dependent hyperpolarization in rabbit mesenteric arteries. J Physiol 1995;498:723-734.
26. Ignarro LJ, Lippton H, Edwards JC, Baricos WH, Hyman AL, Kadowitz PJ, Gruetter CA. Mechanism of vascular smooth muscle relaxation by organic nitrates, nitrites, nitroprusside and nitric oxide: evidence for the involvement of s-nitrosothiols or active intermediates. J Pharmacol Exp Ther 1981;218(3):739-749.
27. G-nitro-L-arginine in rat aorta. Eur J Pharmacol 1995;274:25-32.
28. Kawashima S, Hirata K. Regulatory mechanisms of endothelial nitric oxide synthase activity and its modulation by lipids and cytokines. Jpn Circ J 57;4:1193-1197.
29. Chen G and Suzuki H. Calcium dependency of the endothelium-dependent hyperpolarization in smooth muscle of the rabbit carotid artery. J Physiol 1990;421:521-534.
30. Mayhan WG, Faraci FM, Heistad DD. Impairment of endothelium-dependent responses of cerebral arteries in chronic hypertension. Am J Physiol 1987;253:H1435-1440.
31. Tesfarmariam B, Halpern W. Endothelium-dependent and endothelium-independent vasodilation in resistance arteries from hypertensive rats. Hypertension 1988;11;440-444.
32. Linder L, Kiowski W, Bühler FR, Lüscher TF. Indirect evidence for release of endothelium-derived relaxing factor in human forearm circulation in vivo. Circulation 1990;81:1762-1767.
33. Fujii K, Tominaga M, Ohmori S, Kobayashi K, Koga T, Takata Y, Fujishima M. Decreased endothelium-dependent hyperpolarization to acetylcholine in smooth muscle of the mesenteric artery of spontaneously hypertensive rats. Circ Res 1992;70:660-669.
34. Van de Voorde J, Vanheel B, Leusen I. Endothelium-dependent relaxation and hyperpolarization in aorta from control and renal hypertensive rats. Circ Res 1992;70:1-8.
35. Jover B, Herizi A, Vebtre F, Dupont M, Mimran A. Sodium and angiotensin in hypertension induced by long-term nitric oxide blockade. Hypertension 1993:21:944-948.
36. Cunha RS, Cabral MA, Vasquez EC. Evidence that the autonomic nervous system plays a major role in the L-NAME-induced hypertension in conscious rats. Am J Hypertens 1993;6:806-809.
37. Salazar FJ, Alberola A, Pinilla JM, Romero JC, Quesada T. Salt-induced increase in arterial pressure during nitric oxide synthase. Am J Hypertens 1993;21:944-948.
38. Pfister SL, Campbell WB. Arachidonic acid and acetylcholine-induced relaxation of rabbit aorta. Hypertension 1992;20:682-689.
39. Rosolowsky M, Campbell WB. Synthesis of hydroxy-eicosatrienoic (HETEs) and epoxyeicosatrienoic acids (EETs) by cultured bovine coronary artery endothelial cells. Biochem Biophys Acta 1996;1229:267-277.
40. + channels in coronary smooth muscle through a guanine nucleotide binding protein. Circ Res 1997;80:877-884.