Effect of experimental diabetes and growth hormone administration on the strength of colonic anastomoses in rats

European Surgical Research

Volumn 31, Issue 5, 1999, Pages 419-428

  Seyer Hansen, Mikkel ^a   Andreassen, T T ^a   Christensen, H ^a   Oxlund, H ^a  

^a AARHUS UNIVERSITY   (Denmark)

Author keywords

Colonic anastomoses; Diabetes mellitus; Growth hormone; Mechanical strength; Wound healing

Indexed keywords

GROWTH HORMONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COLON; COLON ANASTOMOSIS; CONTROLLED STUDY; DIABETES MELLITUS; FEMALE; NONHUMAN; ORGAN WEIGHT; PRIORITY JOURNAL; RAT; SUTURE; WOUND HEALING;

ANASTOMOSIS, SURGICAL; ANIMALS; BLOOD GLUCOSE; BODY WEIGHT; COLON; DIABETES MELLITUS, EXPERIMENTAL; FEMALE; GROWTH HORMONE; HYDROXYPROLINE; INSULIN-LIKE GROWTH FACTOR I; RATS; RATS, WISTAR; STRESS, MECHANICAL; SURGICAL WOUND DEHISCENCE;

EID: 0032843542     PISSN: 0014312X     EISSN: None     Source Type: Journal    
DOI: 10.1159/000008721     Document Type: Article

References (27)

1. Goodson WH III, Hunt TK: Wound healing and the diabetic patient. Surg Gynecol Obstet 1979;149:600-608.
2. Andreassen TT, Oxlund H: The influence of experimental diabetes and insulin treatments on the biochemical properties of rat skin incisional wounds. Acta Chir Scand 1987;153:405-409.
3. Seyer-Hansen M, Andreassen TT, Jørgensen PH, Oxlund H: Influence of biosynthetic human growth hormone on the biomechanical strength development in skin incisional wounds of diabetic rats. Eur Surg Res 1993;25:162-168.
4. Yue DK, Swanson B, McLennan S, Marsh M, Spaliviero J, Delbridge L, Reeve T, Turtle JR: Abnormalities of granulation tissue and collagen formation in experimental diabetes, uraemia and malnutrition. Diabet Med 1986;3:221-225.
5. Black CT, Hennessey PJ, Ford EG, Andrassy RJ: Protein glycosylation and collagen metabolism in normal and diabetic rats. J Surg Res 1989;47:200-202.
6. Jørgensen, Andreassen TT: Influence of biosynthetic human growth hormone on biomechanical properties of rat skin incisional wounds. Acta Chir Scand 1988;154:623-626.
7. Jørgensen PH, Andreassen TT: A dose-response study of the effects of biosynthetic human growth hormone on formation and strength of granulation tissue. Endocrinology 1987;121:1637-1641.
8. Hastings JC, Winkle WV Jr, Barker E, Hines D, Nichols W: Effect of suture materials on healing wounds of the stomach and colon. Surg Gynecol Obstet 1975;140:701-707.
9. Schneir M, Bowersox J, Ramamurthy N, Yavelow J, Murray J, Edlin-Folz E, Golub L: Response of rat connective tissues to streptozotocin-diabetes. Tissue-specific effects on collagen metabolism. Biochim Biophys Acta 1979;583:95-102.
10. Gottrup F, Andreassen TT: Healing of incisional wounds in stomach and duodenum: The influence of experimental diabetes. J Surg Res 1981;31:61-68.
11. Verhofstad MHJ, Hendriks T: Diabetes impairs the development of early strength, but not the accumulation of collagen, during intestinal anastomotic healing in the rat. Br J Surg 1994;81:1040-1045.
12. Verhofstad MHJ, Hendriks T: Complete prevention of impaired anastomotic healing in diabetic rats requires preoperative blood glucose control. Br J Surg 1996;83:1717-1721.
13. Nowak TV, Harrington B, Weisbruch JP, Kalbfleisch JH: Structural and functional characteristics of muscle from diabetic rodent small intestine. Am J Physiol 1990;258:G690-698
14. Pillion DJ, Jenkins RL, Atchison JA, Stockard CR, Clements RS Jr, Grizzle WE: Paradoxical organ-specific adaptations to streptozotocin diabetes mellitus in adult rats. Am J Physiol 1988;254:E749-755.
15. Christensen H, Oxlund H, Laurberg S: Growth hormone increases the bursting strength of colonic anastomoses. An experimental study in the rat. Int J Colorectal Dis 1990;5:130-134.
16. Flyvbjerg A, Ørskov H: Kidney tissue insulin-like growth factor I and initial renal growth in diabetic rats. Relation to severity of diabetes. Acta Endocrinol 1990;122:374-378.
17. Woessner JF Jr: Determination of hydroxyproline in connective tissues; in Hall DA (ed): The methodology of Connective Tissue Research. Oxford, Joynson-Bruvvers, 1976, pp 227-233.
18. Jönsson K, Jiborn H, Zederfeldt B: Breaking strength of small intestinal anastomoses. Am J Surg 1983;145:800-803.
19. Cronin K, Jackson DS, Dunphy JE: Changing bursting strength and collagen content of the healing colon. Surg Gynecol Obstet 1968;126:747-753.
20. Hendriks T, Mastboom WJB: Healing of experimental intestinal anastomoses. Parameters for repair. Dis Colon Rectum 1990;33:891-901.
21. Foschi D, Corsi F, Cellerino P, Cassini P, Trabucchi E: Diabetes impairs the development of early strength, but not the accumulation of collagen during intestinal healing in the rat. A correspondence. Br J Surg 1995;82:423-424.
22. Ahrendt GM, Gardner K, Barbul A: Loss of colonic structural collagen impairs healing during intra-abdominal sepsis. Arch Surg 1994;129:1179-1183.
23. Jørgensen PH, Oxlund H: Growth hormone increases the biomechanical strength and collagen deposition rate during the early phase of skin wound healing. Wound Rep Reg 1996;4:40-47.
24. Oxlund H, Christensen H, Seyer-Hansen M, Andreassen TT: Collagen deposition and mechanical strength of colon anastomoses and skin incisional wounds of rats. J Surg Res 1996;66:25-30.
25. Scheiwiller E, Guler HP, Merryweather J, Scandella C, Maerki W, Zapf J, Froesch ER: Growth restoration of insulin-deficient diabetic rats by recombinant human insulin-like growth factor 1. Nature 1986;323:169-171.
26. Maes M, Underwood LE, Ketelslegers JM: Low serum somatomedin-C in insulin-dependent diabetes: Evidence for a postreceptor mechanism. Endocrinology 1986;118:377-382.
27. Seyer-Hansen K: Renal hypertrophy in streptozotocin-diabetic rats. Clin Sci Mol Med Suppl 1976;51:551-555.