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Volumn 43, Issue 10, 1999, Pages 2468-2472

Decreased azithromycin susceptibility of Neisseria gonorrhoeae due to mtrR mutations

Author keywords

[No Author keywords available]

Indexed keywords

AZITHROMYCIN; ERYTHROMYCIN; TETRACYCLINE; TRITON X 100;

EID: 0032842433     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/aac.43.10.2468     Document Type: Article
Times cited : (119)

References (46)
  • 1
    • 0022593198 scopus 로고
    • Plasmid-mediated high-level resistance to erythromycin in Escherichia coli
    • Andremont, A., G. Gerbaud, and P. Courvalin. 1986. Plasmid-mediated high-level resistance to erythromycin in Escherichia coli. Antimicrob. Agents Chemother. 29:515-518.
    • (1986) Antimicrob. Agents Chemother. , vol.29 , pp. 515-518
    • Andremont, A.1    Gerbaud, G.2    Courvalin, P.3
  • 2
    • 0023127236 scopus 로고
    • Distribution of erythromycin esterase and rRNA methylase genes in members of the family Enterobacteriaceae highly resistant to erythromycin
    • Arthur, M., A. Andremont, and P. Courvalin. 1987. Distribution of erythromycin esterase and rRNA methylase genes in members of the family Enterobacteriaceae highly resistant to erythromycin. Antimicrob. Agents Chemother. 31:404-409.
    • (1987) Antimicrob. Agents Chemother. , vol.31 , pp. 404-409
    • Arthur, M.1    Andremont, A.2    Courvalin, P.3
  • 3
    • 0023056773 scopus 로고
    • Analysis of the nucleotide sequence of the ermB gene encoding the erythrormycin esterase type II
    • Arthur, M., D. Autissier, and P. Courvalin. 1986. Analysis of the nucleotide sequence of the ermB gene encoding the erythrormycin esterase type II. Nucleic Acids Res. 14:4987-4999.
    • (1986) Nucleic Acids Res. , vol.14 , pp. 4987-4999
    • Arthur, M.1    Autissier, D.2    Courvalin, P.3
  • 4
    • 0021674158 scopus 로고
    • Enzymatic hydrolysis of erythromycin by a strain of Escherichia coli: A new mechanism of resistance
    • Barthélémy, P., D. Autissier, G. Gerbaud, and P. Courvalin. 1984. Enzymatic hydrolysis of erythromycin by a strain of Escherichia coli: a new mechanism of resistance. J. Antibiot. 37:1692-1696.
    • (1984) J. Antibiot. , vol.37 , pp. 1692-1696
    • Barthélémy, P.1    Autissier, D.2    Gerbaud, G.3    Courvalin, P.4
  • 6
    • 0023779532 scopus 로고
    • Inactivation of lincosamide antibiotics in Staphylococcus aureus
    • Brisson-Noël, A., P. Delrieu, D. Samain, and P. Courvalin. 1988. Inactivation of lincosamide antibiotics in Staphylococcus aureus. J. Biol. Chem. 263: 15880-15887.
    • (1988) J. Biol. Chem. , vol.263 , pp. 15880-15887
    • Brisson-Noël, A.1    Delrieu, P.2    Samain, D.3    Courvalin, P.4
  • 7
    • 0029008426 scopus 로고
    • Comparative activity of azithromycin against 100 strains of Neisseria gonorrhoeae
    • Chevalier, B., Y. Crenn, J. D. Cavallo, N. Plotton, and M. Meyran. 1995. Comparative activity of azithromycin against 100 strains of Neisseria gonorrhoeae. Pathol. Biol. 43:281-283.
    • (1995) Pathol. Biol. , vol.43 , pp. 281-283
    • Chevalier, B.1    Crenn, Y.2    Cavallo, J.D.3    Plotton, N.4    Meyran, M.5
  • 8
    • 0030788246 scopus 로고    scopus 로고
    • Involvement of the gonococcal MtrE protein in the resistance of Neisseria gonorrhoeae to toxic hydrophobic agents
    • Delahay, R. M., B. D. Robertson, J. T. Balthazar, W. M. Shafer, and C. A. Ison. 1997. Involvement of the gonococcal MtrE protein in the resistance of Neisseria gonorrhoeae to toxic hydrophobic agents. Microbiology 143:2127-2133.
    • (1997) Microbiology , vol.143 , pp. 2127-2133
    • Delahay, R.M.1    Robertson, B.D.2    Balthazar, J.T.3    Shafer, W.M.4    Ison, C.A.5
  • 10
  • 11
    • 0029973117 scopus 로고    scopus 로고
    • A clinical isolate of Neisseria gonorrhoeae with in vitro resistance to erythromycin and decreased susceptibility to azithromycin
    • Ehret, J. M., L. J. Nims, and F. N. Judson. 1996. A clinical isolate of Neisseria gonorrhoeae with in vitro resistance to erythromycin and decreased susceptibility to azithromycin. Sex. Transm. Dis. 23:270-272.
    • (1996) Sex. Transm. Dis. , vol.23 , pp. 270-272
    • Ehret, J.M.1    Nims, L.J.2    Judson, F.N.3
  • 12
    • 0028906903 scopus 로고
    • Resistance of Neisseria gonorrhoeae to antimicrobial hydrophobic agents is modulated by the mtrRCDE efflux system
    • Hagman, K. E., W. Pan, B. G. Spratt, J. T. Balthazar, R. C. Judd, and W. M. Shafer. 1995. Resistance of Neisseria gonorrhoeae to antimicrobial hydrophobic agents is modulated by the mtrRCDE efflux system. Microbiology 141: 611-622.
    • (1995) Microbiology , vol.141 , pp. 611-622
    • Hagman, K.E.1    Pan, W.2    Spratt, B.G.3    Balthazar, J.T.4    Judd, R.C.5    Shafer, W.M.6
  • 13
    • 0030788726 scopus 로고    scopus 로고
    • The MtrD protein of Neisseria gonorrhoeae is a member of the resistance/nodulation/division protein family constituting part of an efflux system
    • Hagman, K. E., C. E. Lucas, J. T. Balthazar, L. Snyder, M. Nilles, R. C. Judd, and W. M. Shafer. 1997. The MtrD protein of Neisseria gonorrhoeae is a member of the resistance/nodulation/division protein family constituting part of an efflux system. Microbiology 131:2117-2125.
    • (1997) Microbiology , vol.131 , pp. 2117-2125
    • Hagman, K.E.1    Lucas, C.E.2    Balthazar, J.T.3    Snyder, L.4    Nilles, M.5    Judd, R.C.6    Shafer, W.M.7
  • 14
    • 0029078189 scopus 로고
    • Transcriptional control of the mtr efflux system of Neisseria gonorrhoeae
    • Hagman, K. E., and W. Shafer. 1995. Transcriptional control of the mtr efflux system of Neisseria gonorrhoeae. J. Bacteriol. 177:4162-4165.
    • (1995) J. Bacteriol. , vol.177 , pp. 4162-4165
    • Hagman, K.E.1    Shafer, W.2
  • 15
    • 0028354982 scopus 로고
    • Multicenter trial of single-dose azithromycin vs. ceftriaxone in the treatment of uncomplicated gonorrhea
    • Handsfield, H. H., Z. A. Dalu, D. J. Martin, J. M. Douglas, Jr., J. M. McCarty, D. Schlossberg, and the Azithromycin Gonorrhea Study Group. 1994. Multicenter trial of single-dose azithromycin vs. ceftriaxone in the treatment of uncomplicated gonorrhea. Sex. Transm. Dis. 21:107-111.
    • (1994) Sex. Transm. Dis. , vol.21 , pp. 107-111
    • Handsfield, H.H.1    Dalu, Z.A.2    Martin, D.J.3    Douglas J.M., Jr.4    McCarty, J.M.5    Schlossberg, D.6
  • 16
    • 0025047817 scopus 로고
    • Characterization of plasmids that confer inducible resistance to 14-membered macrolides and streptogramin type B antibiotics in Slaphylococcus aureus
    • Janosi, L., Y. Nakajima, and H. Hashimoto. 1990. Characterization of plasmids that confer inducible resistance to 14-membered macrolides and streptogramin type B antibiotics in Slaphylococcus aureus. Microbiol. Immunol. 34:723-735.
    • (1990) Microbiol. Immunol. , vol.34 , pp. 723-735
    • Janosi, L.1    Nakajima, Y.2    Hashimoto, H.3
  • 17
    • 0026787432 scopus 로고
    • Purification and characterization of macrolide 2'-phosphotransferase type II from a strain of Escherichia coli highly resistant to macrolide antibiotics
    • Kono, M., K. O'Hara, and T. Ebisu. 1992. Purification and characterization of macrolide 2'-phosphotransferase type II from a strain of Escherichia coli highly resistant to macrolide antibiotics. FEMS Microbiol. Lett. 97:89-94.
    • (1992) FEMS Microbiol. Lett. , vol.97 , pp. 89-94
    • Kono, M.1    O'Hara, K.2    Ebisu, T.3
  • 18
    • 0015043629 scopus 로고
    • Altered methylation of ribosomal RNA in an erythromycin-resistant strain of Staphylococcus aureus
    • Lai, C., and B. Weisblum. 1971. Altered methylation of ribosomal RNA in an erythromycin-resistant strain of Staphylococcus aureus. Proc. Natl. Acad. Sci. USA 68:856-860.
    • (1971) Proc. Natl. Acad. Sci. USA , vol.68 , pp. 856-860
    • Lai, C.1    Weisblum, B.2
  • 19
    • 0023485789 scopus 로고
    • Phenotypic expression and genetic heterogeneity of lincosamide inactivation in Staphylococcus spp
    • Leclercq, R., A. Brisson-Noël, J. Duval, and P. Courvalin. 1987. Phenotypic expression and genetic heterogeneity of lincosamide inactivation in Staphylococcus spp. Antimicrob. Agents Chemother. 31:1887-1891.
    • (1987) Antimicrob. Agents Chemother. , vol.31 , pp. 1887-1891
    • Leclercq, R.1    Brisson-Noël, A.2    Duval, J.3    Courvalin, P.4
  • 20
    • 0025821199 scopus 로고
    • Bacterial resistance to macrolide, lincosamide, and streptogramin antibiotics by target modification
    • Leclercq, R., and P. Courvalin. 1991. Bacterial resistance to macrolide, lincosamide, and streptogramin antibiotics by target modification. Antimicrob. Agents Chemother. 35:1267-1272.
    • (1991) Antimicrob. Agents Chemother. , vol.35 , pp. 1267-1272
    • Leclercq, R.1    Courvalin, P.2
  • 21
    • 0025786957 scopus 로고
    • Intrinsic and unusual resistance to macrolide, lincosamide, and streptogramin antibiotics in bacteria
    • Leclercq, R., and P. Courvalin. 1991. Intrinsic and unusual resistance to macrolide, lincosamide, and streptogramin antibiotics in bacteria. Antimicrob. Agents Chemother. 35:1273-1276.
    • (1991) Antimicrob. Agents Chemother. , vol.35 , pp. 1273-1276
    • Leclercq, R.1    Courvalin, P.2
  • 23
    • 0030798952 scopus 로고    scopus 로고
    • The MtrR repressor binds the DNA sequence between the mtrR and mtrC genes of Neisseria gonorrhoeae
    • Lucas, C. E., J. T. Balthazar, K. E. Hagman, and W. M. Shafer. 1997. The MtrR repressor binds the DNA sequence between the mtrR and mtrC genes of Neisseria gonorrhoeae. J. Bacteriol. 179:4123-4128.
    • (1997) J. Bacteriol. , vol.179 , pp. 4123-4128
    • Lucas, C.E.1    Balthazar, J.T.2    Hagman, K.E.3    Shafer, W.M.4
  • 24
    • 0029113544 scopus 로고
    • Importance of lipooligosaccharide structure in determining gonococcal resistance to hydrophobic antimicrobial agents resulting from the mtr efflux system
    • Lucas, C. E., K. E. Hagman, J. C. Levin, D. C. Stein, and W. M. Shafer. 1995. Importance of lipooligosaccharide structure in determining gonococcal resistance to hydrophobic antimicrobial agents resulting from the mtr efflux system. Mol. Microbiol. 16:1001-1009.
    • (1995) Mol. Microbiol. , vol.16 , pp. 1001-1009
    • Lucas, C.E.1    Hagman, K.E.2    Levin, J.C.3    Stein, D.C.4    Shafer, W.M.5
  • 27
    • 0027370872 scopus 로고
    • Analysis in Neisseria meningitidis and other Neisseria species of genes homologous to the FKBP immunophilin family
    • McAllister, C. F., and D. S. Stephens. 1993. Analysis in Neisseria meningitidis and other Neisseria species of genes homologous to the FKBP immunophilin family. Mol. Microbiol. 10:13-24.
    • (1993) Mol. Microbiol. , vol.10 , pp. 13-24
    • McAllister, C.F.1    Stephens, D.S.2
  • 30
    • 23444456920 scopus 로고
    • Prevention of drug access to bacterial targets: Permeability barriers and active efflux
    • Nikaido, H. 1994. Prevention of drug access to bacterial targets: permeability barriers and active efflux. Science 64:382-388.
    • (1994) Science , vol.64 , pp. 382-388
    • Nikaido, H.1
  • 31
    • 0029845913 scopus 로고    scopus 로고
    • Multidrug efflux pumps of Gram-negative bacteria
    • Nikaido, H. 1996. Multidrug efflux pumps of Gram-negative bacteria. J. Bacteriol. 178:5853-5859.
    • (1996) J. Bacteriol. , vol.178 , pp. 5853-5859
    • Nikaido, H.1
  • 32
    • 0024365434 scopus 로고
    • Purification and characterization of macrolide 2′-phosphotransferase from a strain of Escherichia coli that is highly resistant to erythromycin
    • O'Hara, K., T. Kanda, K. Ohmiya, T. Ebisu, and M. Kono. 1989. Purification and characterization of macrolide 2′-phosphotransferase from a strain of Escherichia coli that is highly resistant to erythromycin. Antimicrob. Agents Chemother. 33:1354-1357.
    • (1989) Antimicrob. Agents Chemother. , vol.33 , pp. 1354-1357
    • O'Hara, K.1    Kanda, T.2    Ohmiya, K.3    Ebisu, T.4    Kono, M.5
  • 33
    • 0028364451 scopus 로고
    • Regulation of the permeability of the gonococcal cell envelope by the mir system
    • Pan, W., and B. G. Spralt. 1994. Regulation of the permeability of the gonococcal cell envelope by the mir system. Mol. Microbiol. 11:769-775.
    • (1994) Mol. Microbiol. , vol.11 , pp. 769-775
    • Pan, W.1    Spralt, B.G.2
  • 36
    • 0025456967 scopus 로고
    • Inducible erythromycin resistance in staphylococci is encoded by a member of a ATP-binding transport super gene family
    • Ross, J. I., E. A. Eady, J. H. Cove, W. J. Clunliffe, S. Baumberg, and J. Wootton. 1990. Inducible erythromycin resistance in staphylococci is encoded by a member of a ATP-binding transport super gene family. Mol. Microbiol. 4:1207-1214.
    • (1990) Mol. Microbiol. , vol.4 , pp. 1207-1214
    • Ross, J.I.1    Eady, E.A.2    Cove, J.H.3    Clunliffe, W.J.4    Baumberg, S.5    Wootton, J.6
  • 37
    • 0021264835 scopus 로고
    • Identification of an envelope mutation (env-10) resulting in increased antibiotic susceptibility and pyocin resistance in a clinical isolate of Neisseria gonorrhoeae
    • Shafer, W. M., M. Guymon, L. F. Lind, and P. F. Sparling. 1984. Identification of an envelope mutation (env-10) resulting in increased antibiotic susceptibility and pyocin resistance in a clinical isolate of Neisseria gonorrhoeae. Antimicrob. Agents Chemother. 25:767-769.
    • (1984) Antimicrob. Agents Chemother. , vol.25 , pp. 767-769
    • Shafer, W.M.1    Guymon, M.2    Lind, L.F.3    Sparling, P.F.4
  • 38
    • 0028997376 scopus 로고
    • Missense mutations that alter the DNA-binding domain of the MtrR protein occur frequently in rectal isolates of Neisseria gonorrhoeae that are resistant to faecal lipids
    • Shafer, W. M., J. T. Balthazar, K. E. Hagman, and S. A. Morse. 1995. Missense mutations that alter the DNA-binding domain of the MtrR protein occur frequently in rectal isolates of Neisseria gonorrhoeae that are resistant to faecal lipids. Microbiology 141:907-911.
    • (1995) Microbiology , vol.141 , pp. 907-911
    • Shafer, W.M.1    Balthazar, J.T.2    Hagman, K.E.3    Morse, S.A.4
  • 39
    • 0025103396 scopus 로고
    • In-vitro activity of azithromycin, erythromycin, ciprofloxacin and norfloxacin against Neisseria gonorrhoeae, Haemophilus ducreyi, and Chlamydia trachomatis
    • Slaney, L., H. Chubb, A. Ronald, and R Brunham. 1990. In-vitro activity of azithromycin, erythromycin, ciprofloxacin and norfloxacin against Neisseria gonorrhoeae, Haemophilus ducreyi, and Chlamydia trachomatis. J. Antimicrob. Chemother. 25(Suppl. A):1-5.
    • (1990) J. Antimicrob. Chemother. , vol.25 , Issue.SUPPL. A , pp. 1-5
    • Slaney, L.1    Chubb, H.2    Ronald, A.3    Brunham, R.4
  • 40
    • 0031962577 scopus 로고    scopus 로고
    • Expression of Pseudomonas aeruginosa multidrug efflux pumps MexA-MexB-OprM and MexC-MexD-OprJ in a multidrug-sensitive Escherichia coli strain
    • Srikumar, R., T. Kon, N. Gotoh, and K. Poole. 1998. Expression of Pseudomonas aeruginosa multidrug efflux pumps MexA-MexB-OprM and MexC-MexD-OprJ in a multidrug-sensitive Escherichia coli strain. Antimicrob. Agents Chemother. 42:65-71.
    • (1998) Antimicrob. Agents Chemother. , vol.42 , pp. 65-71
    • Srikumar, R.1    Kon, T.2    Gotoh, N.3    Poole, K.4
  • 42
    • 0028123405 scopus 로고
    • Single dose azithromycin treatment of gonorrhea and infections caused by C. trachomatis and U. urealyticum in men
    • Steingrimsson, O., J. H. Ólafsson, H. Thórarinsson, R. W. Ryan, R. B. Johnson, and R. C. Tilton. 1994. Single dose azithromycin treatment of gonorrhea and infections caused by C. trachomatis and U. urealyticum in men. Sex. Transm. Dis. 21:43-46.
    • (1994) Sex. Transm. Dis. , vol.21 , pp. 43-46
    • Steingrimsson, O.1    Ólafsson, J.H.2    Thórarinsson, H.3    Ryan, R.W.4    Johnson, R.B.5    Tilton, R.C.6
  • 43
    • 0029849428 scopus 로고    scopus 로고
    • Streptococcus pneumoniae and Streptococcus pyogenes resistant to macrolides but sensitive to clindamycin: A common resistance pattern mediated by an efflux system
    • Sutcliffe, J., A. Tait Kamradt, and L. Wondrack. 1996. Streptococcus pneumoniae and Streptococcus pyogenes resistant to macrolides but sensitive to clindamycin: a common resistance pattern mediated by an efflux system. Antimicrob. Agents Chemother. 40:1817-1824.
    • (1996) Antimicrob. Agents Chemother. , vol.40 , pp. 1817-1824
    • Sutcliffe, J.1    Tait Kamradt, A.2    Wondrack, L.3
  • 44
    • 0031728402 scopus 로고    scopus 로고
    • Failure of azithromycin therapy in gonorrhea and discorrelation with laboratory test parameters
    • Tapsall, J. W., E. A. Limnios, B. Donovan, G. Lum, and B. P. Mulhall. 1998. Failure of azithromycin therapy in gonorrhea and discorrelation with laboratory test parameters. Sex. Transm. Dis. 25:505-508.
    • (1998) Sex. Transm. Dis. , vol.25 , pp. 505-508
    • Tapsall, J.W.1    Limnios, E.A.2    Donovan, B.3    Lum, G.4    Mulhall, B.P.5
  • 45
    • 0027290727 scopus 로고
    • Open study of the safety and efficacy of a single oral dose of azithromycin for the treatment of uncomplicated gonorrhea in men and women
    • Waugh, M. A. 1993. Open study of the safety and efficacy of a single oral dose of azithromycin for the treatment of uncomplicated gonorrhea in men and women. J. Antimicrob. Chemother. 31(Suppl. E):193-198.
    • (1993) J. Antimicrob. Chemother. , vol.31 , Issue.SUPPL. E , pp. 193-198
    • Waugh, M.A.1
  • 46
    • 0030920167 scopus 로고    scopus 로고
    • Azithromycin and erythromycin resistant Neisseria gonorrhoeae following treatment with azithromycin
    • Young, H., A. Moyes, and A. McMillan. 1997. Azithromycin and erythromycin resistant Neisseria gonorrhoeae following treatment with azithromycin. Int. J. Sex. Transm. Dis. AIDS 8:299-302.
    • (1997) Int. J. Sex. Transm. Dis. AIDS , vol.8 , pp. 299-302
    • Young, H.1    Moyes, A.2    McMillan, A.3


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