Bronchial hyperresponsiveness and airway wall remodelling induced by exposure to allergen for 9 weeks

Allergy: European Journal of Allergy and Clinical Immunology

Volumn 54, Issue 10, 1999, Pages 1074-1082

  Cui, Zhi Hua ^a   Skoogh, B E ^a   Pullerits, T ^a   Lotvall J ^a  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

Airway narrowing; Bronchial responsiveness; Brown Norway rat; Goblet cell; IgE; IgG antibodies; Trimellitic anhydride

Indexed keywords

ACETYLCHOLINE; ALLERGEN; IMMUNOGLOBULIN E ANTIBODY; IMMUNOGLOBULIN G ANTIBODY; SERUM ALBUMIN; TRIMELLITIC ANHYDRIDE;

AIRWAY CONDUCTANCE; AIRWAY OBSTRUCTION; AIRWAY WALL REMODELLING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTHMA; BRONCHUS HYPERREACTIVITY; CELL HYPERPLASIA; CONTROLLED STUDY; EOSINOPHILIA; GOBLET CELL; LUNG RESISTANCE; MALE; NONHUMAN; OCCUPATIONAL EXPOSURE; PRIORITY JOURNAL; RAT;

AIRWAY RESISTANCE; ALLERGENS; ANIMALS; ANTIBODIES; BRONCHI; BRONCHIAL HYPERREACTIVITY; ENVIRONMENTAL EXPOSURE; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; MALE; MUSCLE, SMOOTH; PHTHALIC ANHYDRIDES; RATS; RATS, INBRED BN; RESPIRATORY SYSTEM; SPECIFIC PATHOGEN-FREE ORGANISMS; TIME FACTORS;

EID: 0032842288     PISSN: 01054538     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1398-9995.1999.00133.x     Document Type: Article

References (34)

1. Barnes PJ, Rodger IW, Thomson NC. Pathogenesis of asthma. In: Barnes PJ, Rodger IW, Thomson NC, editors. Asthma: basic mechanisms and clinical management. London: Academic Press, 1989:415-444.
2. Chung KF, Barnes PJ. Role of inflammatory mediators in asthma. Br Med Bull 1992;48:135-148.
3. Barnes PJ. New concepts in the pathogenesis of bronchial hyperresponsiveness and asthma. J Allergy Clin Immunol 1989;83:1013-1026.
4. Jakatanon A, Lim S, Kharitonov SA, Chung KF, Barnes PJ. Correlation between exhaled nitric oxide, sputum eosinophils, and methacholine responsiveness in patients with mild asthma. Thorax 1998;53:91-95.
5. Erjefält JS, Korsgren M, Nilsson MC, Sundler F, Persson CG. Association between inflammation and epithelial damage-restitution processes in allergic airways in vivo. Clin Exp Allergy 1997;27:1344-1355.
6. Blyth DI, Pedrick MS, Savage TJ, Hessel EM, Fattah D. Lung inflammation and epithelial changes in a murine model of atopic asthma. Am J Respir Cell Mol Biol 1996;14:425-438.
7. Blyth DI, Pedrick MS, Savage TJ, Bright H, Beesley JE, Sanjar S. Induction, duration, and resolution of airway goblet cell hyperplasia in a murine model of atopic asthma: effect of concurrent infection with respiratory syncytial virus and response to dexamethasone. Am J Respir Cell Mol Biol 1998;19:38-54.
8. Solway J, Fredberg JJ. Perhaps airway smooth muscle dysfunction contributes to asthmatic bronchial hyperresponsiveness after all. Am J Respir Cell Mol Biol 1997;17:144-146.
9. Ihre E, Zetterström O. Increase in non-specific bronchial responsiveness after repeated inhalation of low doses of allergen. Clin Exp Allergy 1992;23:298-305.
10. Kips JC, Cuvelier CA, Pauwels RA. Effect of acute and chronic antigen inhalation on airway morphology and responsiveness in actively sensitised rats. Am Rev Respir Dis 1992;145:1306-1310.
11. Haczku A, Moqbel R, Elwood W, et al. Effects of prolonged repeated exposure to ovalbumin in sensitised brown Norway rats. Am J Respir Crit Care Med 1994;150:23-27.
12. Cui ZH, Sjöstrand M, Pullerits T, Andius P, Skoogh BE, Lötvall J. Bronchial hyperresponsiveness, epithelial damage, and airway eosinophilia after single and repeated allergen exposure in a rat model of anhydride-induced asthma. Allergy 1997;52:739-746.
13. Eggleston PA, Rosenstreich D, Lynn H, et al. Relationship of indoor allergen exposure to skin test sensitivity in inner-city children with asthma. J Allergy Clin Immunol 1998;102:563-570.
14. Ishida K, Kelly LJ, Thomson RT, Beattie LL, Schellenberg RR. Repeated antigen challenge induces airway hyperresponsiveness with tissue eosinophilia in guinea pigs. J Appl Physiol 1989;67:1133-1139.
15. Cockcroft DW, Ruffin RE, Hargreave FE. Appearance of allergen-induced increases in airway responsiveness only after repeated allergen inhalations in two subjects. Clin Exp Allergy 1989;19:225-227.
16. Zeiss CR, Wolkonsky P, Pruzansky JJ, Patterson R. Clinical and immunological evaluation of trimellitic anhydride workers in multiple industrial settings. J Allergy Clin Immunol 1982;70:15-18.
17. Hayes JP, Daniel R, Tee RD, Barnes PJ, Newman Taylor AJ, Chung KF. Bronchial hyperreactivity after inhalation of trimellitic anhydride dust in guinea pigs after intradermal sensitization to the free hapten. Am Rev Respir Dis 1992;146:1311-1314.
18. Bai A, Eidelman DH, Hogg JC, et al. Proposed nomenclature for quantifying subdivisions of the bronchial wall. J Appl Physiol 1994;77:1011-1014.
19. Panettieri RA Jr, Murray RK, Eszterhas AJ, Bilgen G, Martin JG. Repeated allergen inhalations induce DNA synthesis in airway smooth muscle and epithelial cells in vivo. Am J Physiol 1998;274:L417-424.
20. Panettieri RA, Yadvish PA, Kelly AM, Rubinstein NA, Kotlikoff MI. Histamine stimulates proliferation of airway smooth muscle and induces c-fos expression. Am J Physiol 1990;259:L365-L371.
21. Noveral JP, Grunstein MM. Role and mechanism of thromboxane-induced proliferation of cultured airway smooth muscle cells. Am J Physiol 1992;263:L555-561.
22. Panettieri RA. Cellular and molecular mechanisms regulating airway smooth muscle proliferation and cell adhesion molecule expression. Am J Respir Crit Care Med 1998;158:S133-140.
23. Padrid P, Snook S, Finucane T, et al. Persistent airway hyperresponsiveness and histologic alterations after chronic antigen challenge in cats. Am J Respir Crit Care Med 1995;151:184-193.
24. Carter PM, Heinly TL, Yates SW, Lieberman PL. Asthma: the irreversible airways disease. J Investig Allergol Clin Immunol 1997;7:566-571.
25. 4 receptor antagonist, Pranlukast, or an interleukin-5 monoclonal antibody. Am J Respir Crit Med 1996;154:850-857.
26. Munoz NM, Leff AR. Blockade of eosinophil migration by 5-lipoxygenase and cyclooxygenase inhibition in explanted guinea pig trachealis. Am J Physiol 1995;268:L446-454.
27. Munoz NM, Douglas I, Mayor D, Herrnreiter A, Zhu XD, Leff AR. Eosinophil chemotaxis inhibited by 5-lipoxygenase blockade and leukotriene receptor antagonism. Am J Respir Crit Care Med 1997;155:1398-1403.
28. Matsuse T, Thomson RJ, Chen XR, Salari H, Schellenberg RR. Capsaicin inhibits airway hyperresponsiveness but not lipoxygenase activity or eosinophilia after repeated aerosolized antigen in guinea pigs. Am Rev Respir Dis 1991;144:368-371.
29. Watson JW, Cohan VL, Shay AK, Freiert KW. Multiple antigen challenge produces pulmonary cosinophilia but not pulmonary hyperresponsiveness in actively sensitised guinea pigs. Agents Actions 1992;37:174-177.
30. Chand N, Nolan K, Diamantis W, Sofia RD. Repeated aeroallergen challenge induces lung dysfunction but not bronchial hyperresponsiveness in conscious guinea pigs. Agents Actions 1992;37:181-183.
31. Twentyman OP, Hood SV, Holgate ST. Does baseline airway caliber affect measurements of airway responsiveness to histamine? J Appl Physiol 1993;74:3034-3039.
32. Tattersfield AE. Measurement of bronchial reactivity: a question of interpretation. Thorax 1981;36:561-565.
33. Leach CL, Hatoum NS, Zeiss CR, Garvin PJ. Immunologic tolerance in rats during 13 weeks of inhalation exposure to trimellitic anhydride. Fundam Appl Toxicol 1989;12:519-529.
34. Holt PG, McMenamin C. Defence against allergic sensitization in the healthy lung: the role of inhalation tolerance. Clin Exp Allergy 1989;19:255-262.