메뉴 건너뛰기




Volumn 10, Issue 5, 1999, Pages 483-495

Comparison of the pharmacological properties of classical and novel BZ-ω receptor ligands

Author keywords

Abecarnil; Anxiety; Ataxia; Benzodiazepines; Binding; Convulsions; Imidazenil; Mouse; Myorelaxation; Omega receptors; Rat; RWJ 46771; SX 3228; Y 23684

Indexed keywords

1,6 NAPHTHYRIDIN 5 ONE DERIVATIVE; 2 (4 CHLOROPHENYL) 5,6 DIHYDRO [1]BENZOTHIEPINO[5,4 C]PYRIDAZIN 3(2H) ONE 7 OXIDE; ABECARNIL; BENZIMIDAZOLE DERIVATIVE; BENZODIAZEPINE OMEGA RECEPTOR; BENZODIAZEPINE RECEPTOR; BETA CARBOLINE; BRETAZENIL; CLOBAZAM; DIAZEPAM; FLUMAZENIL; IMIDAZENIL; PYRIDAZINONE DERIVATIVE; RECEPTOR SUBTYPE; RWJ 46771; SX 3228; UNCLASSIFIED DRUG;

EID: 0032841771     PISSN: 09558810     EISSN: None     Source Type: Journal    
DOI: 10.1097/00008877-199909000-00007     Document Type: Article
Times cited : (35)

References (46)
  • 1
    • 0000881162 scopus 로고
    • Multiple benzodiazepine receptors
    • Braestrup C, Nielsen M (1980). Multiple benzodiazepine receptors. Trends Neurosci 3:301-303.
    • (1980) Trends Neurosci , vol.3 , pp. 301-303
    • Braestrup, C.1    Nielsen, M.2
  • 2
    • 0027139227 scopus 로고
    • An ethological analysis of the effects of chlordiazepoxide and bretazenil (Ro 166028) in the murine elevated plusmaze
    • Cole JC, Rodgers RJ (1993). An ethological analysis of the effects of chlordiazepoxide and bretazenil (Ro 166028) in the murine elevated plusmaze. Behav Pharmacol 4:573-580.
    • (1993) Behav Pharmacol , vol.4 , pp. 573-580
    • Cole, J.C.1    Rodgers, R.J.2
  • 3
    • 0022613409 scopus 로고
    • Zolpidem, a novel nonbenzodiazepine hypnotic: I. Neuropharmacological and behavioral effects
    • Depoortere H, Zivkovic B, Lloyd KG et al. (1986). Zolpidem, a novel nonbenzodiazepine hypnotic: I. Neuropharmacological and behavioral effects. J Pharmacol Exp Ther 237:649-658.
    • (1986) J Pharmacol Exp Ther , vol.237 , pp. 649-658
    • Depoortere, H.1    Zivkovic, B.2    Lloyd, K.G.3
  • 5
    • 0029933404 scopus 로고    scopus 로고
    • The use of the rat elevated plusmaze to discriminate between non selective and BZ1 (ω) selective, benzodiazepine receptor ligands
    • Griebel G, Sanger DJ, Perrault G (1996a). The use of the rat elevated plusmaze to discriminate between non selective and BZ1 (ω) selective, benzodiazepine receptor ligands. Psychopharmacology (Berl) 124:245-254.
    • (1996) Psychopharmacology (Berl) , vol.124 , pp. 245-254
    • Griebel, G.1    Sanger, D.J.2    Perrault, G.3
  • 6
    • 0030445551 scopus 로고    scopus 로고
    • Further evidence for differences between nonselective and BZ1 (ω) selective, benzodiazepine receptor ligands in murine models of 'state' and 'trait' anxiety
    • Griebel G, Sanger DJ, Perrault G (1996b). Further evidence for differences between nonselective and BZ1 (ω) selective, benzodiazepine receptor ligands in murine models of 'state' and 'trait' anxiety. Neuropharmacology 35:1081-1091.
    • (1996) Neuropharmacology , vol.35 , pp. 1081-1091
    • Griebel, G.1    Sanger, D.J.2    Perrault, G.3
  • 7
    • 0030813322 scopus 로고    scopus 로고
    • Risk assessment behaviour: Evaluation of utility in the study of 5-HT-related drugs in the rat elevated plus-maze test
    • Griebel G, Rodgers RJ, Perrault G, Sanger DJ (1997). Risk assessment behaviour: Evaluation of utility in the study of 5-HT-related drugs in the rat elevated plus-maze test. Pharmacol Biochem Behav 57:817-827.
    • (1997) Pharmacol Biochem Behav , vol.57 , pp. 817-827
    • Griebel, G.1    Rodgers, R.J.2    Perrault, G.3    Sanger, D.J.4
  • 8
    • 0031743698 scopus 로고    scopus 로고
    • Limited anxiolyticlike effects of nonbenzodiazepine hypnotics in rodents
    • Griebel G, Perrault G, Sanger DJ (1998). Limited anxiolyticlike effects of nonbenzodiazepine hypnotics in rodents. J Psychopharmacol 12:356-365.
    • (1998) J Psychopharmacol , vol.12 , pp. 356-365
    • Griebel, G.1    Perrault, G.2    Sanger, D.J.3
  • 9
    • 0028217950 scopus 로고
    • Comparison of several benzodiazepine receptor ligands in two models of anxiolytic activity in the mouse: An analysis based on fractional receptor occupancies
    • Jones GH, Schneider C, Schneider HH, Seidler J, Cole BJ, Stephens DN (1994). Comparison of several benzodiazepine receptor ligands in two models of anxiolytic activity in the mouse: An analysis based on fractional receptor occupancies. Psychopharmacology (Berl) 114:191-199.
    • (1994) Psychopharmacology (Berl) , vol.114 , pp. 191-199
    • Jones, G.H.1    Schneider, C.2    Schneider, H.H.3    Seidler, J.4    Cole, B.J.5    Stephens, D.N.6
  • 11
    • 0002715423 scopus 로고
    • Benzodiazepines: A risk-benefit profile
    • Lader M (1994). Benzodiazepines: a risk-benefit profile. CNS Drugs 1:377-387.
    • (1994) CNS Drugs , vol.1 , pp. 377-387
    • Lader, M.1
  • 12
    • 0024157342 scopus 로고
    • Imidazopyridines as a tool for the characterization of benzodiazepine receptors: A proposal for a pharmacological classification as omega receptor subtypes
    • Langer SZ, Arbilla S (1988). Imidazopyridines as a tool for the characterization of benzodiazepine receptors: a proposal for a pharmacological classification as omega receptor subtypes. Pharmacol Biochem Behav 29:763-766.
    • (1988) Pharmacol Biochem Behav , vol.29 , pp. 763-766
    • Langer, S.Z.1    Arbilla, S.2
  • 13
    • 0025579881 scopus 로고
    • Zolpidem and alpidem: Two imidazopyridines with selectivity for ω1 and ω3 receptor subtypes
    • Langer SZ, Arbilla S, Benavides J, Scatton B (1990). Zolpidem and alpidem: two imidazopyridines with selectivity for ω1 and ω3 receptor subtypes. Adv Biochem Psychopharmacol 46:61-72.
    • (1990) Adv Biochem Psychopharmacol , vol.46 , pp. 61-72
    • Langer, S.Z.1    Arbilla, S.2    Benavides, J.3    Scatton, B.4
  • 14
    • 0017365089 scopus 로고
    • Effect of convulsant and anticonvulsant agents on level and metabolism of gamma-aminobutyric acid in mouse brain
    • Löscher W, Frey HH (1977). Effect of convulsant and anticonvulsant agents on level and metabolism of gamma-aminobutyric acid in mouse brain. Naunyn Schmiedebergs Arch Pharmacol 296:263-269.
    • (1977) Naunyn Schmiedebergs Arch Pharmacol , vol.296 , pp. 263-269
    • Löscher, W.1    Frey, H.H.2
  • 15
    • 0028986131 scopus 로고
    • A benzodiazepine receptor heterogeneity: Neurophysiological implications
    • A benzodiazepine receptor heterogeneity: neurophysiological implications. Neuropharmacology 34:245-254.
    • (1995) Neuropharmacology , vol.34 , pp. 245-254
    • Luddens, H.1    Korpi, E.R.2    Seeburg, P.H.3
  • 16
    • 34250403804 scopus 로고
    • Evidence for an involvement of GABA in the mediation of the cerebellar cGMP decrease and the anticonvulsant action diazepam
    • Mao CC, Guidotti A, Costa E (1975). Evidence for an involvement of GABA in the mediation of the cerebellar cGMP decrease and the anticonvulsant action diazepam. Naunyn Schmiedebergs Arch Pharmacol 289:369-378.
    • (1975) Naunyn Schmiedebergs Arch Pharmacol , vol.289 , pp. 369-378
    • Mao, C.C.1    Guidotti, A.2    Costa, E.3
  • 17
    • 0024216317 scopus 로고
    • Ro 166028: A novel anxiolytic acting as a partial agonist at the benzodiazepine receptor
    • Martin JR, Pieri L, Bonetti EP et al. (1988). Ro 166028: a novel anxiolytic acting as a partial agonist at the benzodiazepine receptor. Pharmacopsychiatry 21:360-362.
    • (1988) Pharmacopsychiatry , vol.21 , pp. 360-362
    • Martin, J.R.1    Pieri, L.2    Bonetti, E.P.3
  • 18
    • 0029058203 scopus 로고
    • Potential anxiolytic agents. Pyrido[1,2 alpha]benzimidazoles: A new structural class of ligands for the benzodiazepine binding site on GABAA receptors
    • Maryanoff BE, Ho W, McComsey DF et al. (1995). Potential anxiolytic agents. Pyrido[1,2 alpha]benzimidazoles: A new structural class of ligands for the benzodiazepine binding site on GABAA receptors. J Med Chem 38:16-20.
    • (1995) J Med Chem , vol.38 , pp. 16-20
    • Maryanoff, B.E.1    Ho, W.2    McComsey, D.F.3
  • 19
    • 0030442976 scopus 로고    scopus 로고
    • Recent progress in development of psychotropic drugs (5) hypnotics
    • Ohta T (1996). Recent progress in development of psychotropic drugs (5) Hypnotics. Jpn J Psychopharmacol 16:161-170.
    • (1996) Jpn J Psychopharmacol , vol.16 , pp. 161-170
    • Ohta, T.1
  • 20
    • 0022374863 scopus 로고
    • Validation of open:Closed arm entries in an elevated plusmaze as a measure of anxiety in the rat
    • Fellow S, Chopin P, File SE, Briley M (1985). Validation of open:closed arm entries in an elevated plusmaze as a measure of anxiety in the rat. J Neurosci Meth 14:149-167.
    • (1985) J Neurosci Meth , vol.14 , pp. 149-167
    • Fellow, S.1    Chopin, P.2    File, S.E.3    Briley, M.4
  • 21
    • 0025131236 scopus 로고
    • Differences in pharmacological profiles of a new generation of benzodiazepine and nonbenzodiazepine hypnotics
    • Perrault G, Morel E, Sanger DJ, Zivkovic B (1990). Differences in pharmacological profiles of a new generation of benzodiazepine and nonbenzodiazepine hypnotics. Eur J Pharmacol 187:487-494.
    • (1990) Eur J Pharmacol , vol.187 , pp. 487-494
    • Perrault, G.1    Morel, E.2    Sanger, D.J.3    Zivkovic, B.4
  • 22
    • 0026768488 scopus 로고
    • Lack of tolerance and physical dependence upon repeated treatment with the novel hypnotic zolpidem
    • Perrault G, Morel E, Sanger DJ, Zivkovic B (1992). Lack of tolerance and physical dependence upon repeated treatment with the novel hypnotic zolpidem. J Pharmacol Exp Ther 263:298-303.
    • (1992) J Pharmacol Exp Ther , vol.263 , pp. 298-303
    • Perrault, G.1    Morel, E.2    Sanger, D.J.3    Zivkovic, B.4
  • 25
    • 0028901230 scopus 로고
    • The behavioural effects of novel benzodiazepine (ω) receptor agonists and partial agonists: Increases in punished responding and antagonism of the pentylenetetrazole cue
    • Sanger DJ (1995). The behavioural effects of novel benzodiazepine (ω) receptor agonists and partial agonists: Increases in punished responding and antagonism of the pentylenetetrazole cue, Behav Pharmacol 6:116-126.
    • (1995) Behav Pharmacol , vol.6 , pp. 116-126
    • Sanger, D.J.1
  • 26
    • 0021956720 scopus 로고
    • Behavioral effects of nonbenzodiazepine anxiolytic drugs: A comparison of CGS 9896 and zopiclone with chlordiazepoxide
    • Sanger DJ, Joly D and Zivkovic B (1985). Behavioral effects of nonbenzodiazepine anxiolytic drugs: a comparison of CGS 9896 and zopiclone with chlordiazepoxide. J Pharmacol Exp Ther 232:831-837.
    • (1985) J Pharmacol Exp Ther , vol.232 , pp. 831-837
    • Sanger, D.J.1    Joly, D.2    Zivkovic, B.3
  • 27
    • 0028145897 scopus 로고
    • Recent developments in the behavioral pharmacology of benzodiazepine (ω) receptors: Evidence for the functional significance of receptor subtypes
    • Sanger DJ, Benavides J, Perrault G et al. (1994). Recent developments in the behavioral pharmacology of benzodiazepine (ω) receptors: Evidence for the functional significance of receptor subtypes. Neurosci Biobehav Rev 18:355-372.
    • (1994) Neurosci Biobehav Rev , vol.18 , pp. 355-372
    • Sanger, D.J.1    Benavides, J.2    Perrault, G.3
  • 28
    • 0029114751 scopus 로고
    • Benzodiazepine (ω) receptor partial agonists and the acquisition of conditioned fear in mice
    • Sanger DJ, Joly D, Perrault G (1995). Benzodiazepine (ω) receptor partial agonists and the acquisition of conditioned fear in mice. Psychopharmacology (Berl) 121:104-108.
    • (1995) Psychopharmacology (Berl) , vol.121 , pp. 104-108
    • Sanger, D.J.1    Joly, D.2    Perrault, G.3
  • 29
    • 8244235137 scopus 로고    scopus 로고
    • Neurochemical characteristics of amisulpride, an atypical dopamine D2/D3 receptor antagonist with both presynaptic and limbic selectivity
    • Schocmaker H, Claustre Y, Fage D et al. (1997). Neurochemical characteristics of amisulpride, an atypical dopamine D2/ D3 receptor antagonist with both presynaptic and limbic selectivity. J Pharmacol Exp Ther 280:83-97.
    • (1997) J Pharmacol Exp Ther , vol.280 , pp. 83-97
    • Schoemaker, H.1    Claustre, Y.2    Fage, D.3
  • 32
    • 0028981088 scopus 로고
    • A receptor subtypes
    • A receptor subtypes. Pharmacol Rev 47:181-234.
    • (1995) Pharmacol Rev , vol.47 , pp. 181-234
    • Sieghart, W.1
  • 33
    • 0021670674 scopus 로고
    • Affinity of various ligands for benzodiazepine receptors in rat cerebellum and hippocampus
    • Sighart W, Schuster A (1984). Affinity of various ligands for benzodiazepine receptors in rat cerebellum and hippocampus. Pharmacol Biochem Behav 33:4033-4038.
    • (1984) Pharmacol Biochem Behav , vol.33 , pp. 4033-4038
    • Sieghart, W.1    Schuster, A.2
  • 34
    • 0018389322 scopus 로고
    • Some properties of brain specific benzodiazepine receptors: New evidence for multiple receptors
    • Squires RF, Benson DI, Braestrup C et al. (1979). Some properties of brain specific benzodiazepine receptors: new evidence for multiple receptors. Pharmacol Biochem Behav 10:825-830.
    • (1979) Pharmacol Biochem Behav , vol.10 , pp. 825-830
    • Squires, R.F.1    Benson, D.I.2    Braestrup, C.3
  • 35
    • 0028219949 scopus 로고
    • Differential effects of anxiolytic and nonanxiolytic benzodiazepine receptor ligands on performance of a differential reinforcement of low rate (DRL) schedule
    • Stephens DN, Voet B (1994). Differential effects of anxiolytic and nonanxiolytic benzodiazepine receptor ligands on performance of a differential reinforcement of low rate (DRL) schedule. Behav Pharmacol 5:4-14.
    • (1994) Behav Pharmacol , vol.5 , pp. 4-14
    • Stephens, D.N.1    Voet, B.2
  • 36
    • 0025363730 scopus 로고
    • Abecarnil, a metabolically stable, anxioselective betacarboline acting at benzodiazepine receptors
    • Stephens DN, Schneider HH, Kehr W et al. (1990). Abecarnil, a metabolically stable, anxioselective betacarboline acting at benzodiazepine receptors. J Pharmacol Exp Ther 253:334-343.
    • (1990) J Pharmacol Exp Ther , vol.253 , pp. 334-343
    • Stephens, D.N.1    Schneider, H.H.2    Kehr, W.3
  • 37
    • 0001358292 scopus 로고
    • 5-containing omega/benzodiazepine receptor subtype in rat brain
    • 5-containing omega/benzodiazepine receptor subtype in rat brain. Can J Physiol Pharmacol 72:448.
    • (1994) Can J Physiol Pharmacol , vol.72 , pp. 448
    • Tan, S.1    Schoemaker, H.2
  • 38
    • 0025355828 scopus 로고
    • Anticonvulsant action of the betacarboline abecarnil: Studies in rodents and baboon, Papio papio
    • Turski L, Stephens DN, Jensen LH et al. (1990). Anticonvulsant action of the betacarboline abecarnil: studies in rodents and baboon, Papio papio. J Pharmacol Exp Ther 253:344-352.
    • (1990) J Pharmacol Exp Ther , vol.253 , pp. 344-352
    • Turski, L.1    Stephens, D.N.2    Jensen, L.H.3
  • 39
    • 0015004136 scopus 로고
    • A simple and reliable conflict procedure for testing antianxiety agents
    • Vogel JR, Beer B, Clody DE (1971). A simple and reliable conflict procedure for testing antianxiety agents. Psychopharmacologia 21:1-7.
    • (1971) Psychopharmacologia , vol.21 , pp. 1-7
    • Vogel, J.R.1    Beer, B.2    Clody, D.E.3
  • 40
    • 0027530534 scopus 로고
    • Differences in affinity and efficacy of benzodiazepine receptor ligands at recombinant gamma-aminobutyric acid receptor subtypes
    • Wafford KA, Whiting PJ, Kemp JA (1993). Differences in affinity and efficacy of benzodiazepine receptor ligands at recombinant gamma-aminobutyric acid receptor subtypes. Mol Pharmacol 43:240-244.
    • (1993) Mol Pharmacol , vol.43 , pp. 240-244
    • Wafford, K.A.1    Whiting, P.J.2    Kemp, J.A.3
  • 41
    • 0027196059 scopus 로고
    • Differential properties of type I and type II benzodiazepine receptors in mammalian CNS neurones
    • Yakushiji T, Shirasaki T, Munakata M, Hirata A, Akaike N (1993). Differential properties of type I and type II benzodiazepine receptors in mammalian CNS neurones. Br J Pharmacol 109:819-825.
    • (1993) Br J Pharmacol , vol.109 , pp. 819-825
    • Yakushiji, T.1    Shirasaki, T.2    Munakata, M.3    Hirata, A.4    Akaike, N.5
  • 42
    • 0028221912 scopus 로고
    • The pharmacological properties of Y23684, a benzodiazepine receptor partial agonist
    • Yasumatsu H, Morimoto Y, Yamamoto Y et al. (1994). The pharmacological properties of Y23684, a benzodiazepine receptor partial agonist. Br J Pharmacol 111:1170-1178.
    • (1994) Br J Pharmacol , vol.111 , pp. 1170-1178
    • Yasumatsu, H.1    Morimoto, Y.2    Yamamoto, Y.3
  • 43
    • 0009662904 scopus 로고    scopus 로고
    • Anxioselective pharmacological property of Y23684, a benzodiazepine receptor (BZR) partial agonist: A comparison with other BZR agonists
    • Abstract
    • Yasumatsu H, Asano K, Morio Y, Matsumoto Y, Takehara S (1998). Anxioselective pharmacological property of Y23684, a benzodiazepine receptor (BZR) partial agonist: a comparison with other BZR agonists. In: XXIst CINP Congress, Glasgow (Abstract).
    • (1998) XXIst CINP Congress, Glasgow
    • Yasumatsu, H.1    Asano, K.2    Morio, Y.3    Matsumoto, Y.4    Takehara, S.5
  • 44
    • 0001839606 scopus 로고
    • Comparative pharmacology of zolpidem and other hypnotics and sleep inducers
    • Sauvanet JP, Langer SZ, Morselli PL (editors). New York: Raven Press
    • Zivkovic B, Perrault G, Morel E, Sanger DJ (1988). Comparative pharmacology of zolpidem and other hypnotics and sleep inducers. In: Imidazopyridines in Sleep Disorders. Sauvanet JP, Langer SZ, Morselli PL (editors). New York: Raven Press.
    • (1988) Imidazopyridines in Sleep Disorders
    • Zivkovic, B.1    Perrault, G.2    Morel, E.3    Sanger, D.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.