Synthesis and antitumor activity of 5'-demethyl-5'-trifluoromethyl-daunorubicin and -doxorubicin

Carbohydrate Research

Volumn 320, Issue 1-2, 1999, Pages 8-18

  Nakai, Ken ^b   Takagi, Yasushi ^a   Ogawa, Seiichiro ^b   Tsuchiya, Tsutomu ^a  

^a Institute of Bio Organic Chemistry   (Japan)

^b KEIO UNIVERSITY   (Japan)

Author keywords

5' demethyl 5' trifluoromethyldoxorubicin; Anthracycline glycoside; Antitumor activity; Trifluoromethyl

Indexed keywords

5' TRIFLUOROMETHYL 5' NORDAUNORUBICIN; 5' TRIFLUOROMETHYL 5' NORDOXORUBICIN; DOXORUBICIN; DOXORUBICIN DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY; INFRARED SPECTROPHOTOMETRY; LEUKEMIA L 1210; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; TUMOR CELL LINE;

TRIFLUORO;

EID: 0032841766     PISSN: 00086215     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0008-6215(99)00126-3     Document Type: Article

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