Effect of dexamethasone on bovine airway smooth muscle cell proliferation

Journal of Asthma

Volumn 36, Issue 6, 1999, Pages 519-525

  Dixon, Earl R ^a   Weinberg, Joseph A ^a   Lew, D Betty ^a,b  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^b Department of Pediatrics ^*  (United States)

Author keywords

Airway smooth muscle; Asthma; Proliferation; Steroids

Indexed keywords

BETA N ACETYLHEXOSAMINIDASE A; DEXAMETHASONE; EPIDERMAL GROWTH FACTOR; GROWTH FACTOR; INSULIN; THYMIDINE;

AIRWAY; ANIMAL EXPERIMENT; ARTICLE; ASTHMA; CATTLE; CELL DIVISION; CELL PROLIFERATION; CONCENTRATION RESPONSE; DNA SYNTHESIS; NONHUMAN; SMOOTH MUSCLE;

EID: 0032841455     PISSN: 02770903     EISSN: None     Source Type: Journal    
DOI: 10.3109/02770909909054558     Document Type: Article

References (35)

1. Heard BE, Hossain S: Hyperplasia of bronchial muscle in asthma. J Pathol 110:319 (1973).
2. Panettieri RA, Yadvish PA, Kelly AM, Korlikoff MK: Histamine stimulates proliferation of airway smooth muscle and induces c-fos expression. Am J Physiol 259:1365 (1990).
3. Lew DB, Rattazzi MC: Mitogenic effect of lysosomal hydrolases on bovine tracheal myocytes in culture. J Clin Invest 88:1969 (1991).
4. Lew DB, Tran N, Weil ML: Inflammatory mediators in airway muscle proliferation. Pediatr Asthma Allergy Immunol 6:267 (1992).
5. Noveral JP, Rosenberg RA, Anbar RA, Pawlowski NA, Grunstein MM: Role of endothelin-1 in regulating proliferation of cultured rabbit airway smooth muscle cells. Am J Physiol 263:L317 (1992).
6. Noveral JP, Grunstein MM: Role and mechanism of thromboxane-induced proliferation of cultured airway smooth muscle cells. Am J Physiol 263:L555 (1992).
7. Brown JK, Jones CA, Tyler CL, Ruoss SJ, Hartmann T, Caughey GH: Tryptase-induced mitogenesis in airway smooth muscle cells. Chest 107:955 (1995).
8. Noveral JP, Grunstein MM: Tachykinin regulation of airway smooth muscle cell proliferation. Am J Physiol 269:L339 (1995).
9. Tonnel AB, Joseph M, Gosset PH, Fourmer E, Capron A: Stimulation of alveolar macrophages in asthmatic patients after local provocation tests. Lancet 25:1406 (1983).
10. Murray JJ, Tonnel AB, Brach AR, Roberts LJ, Gosset P, Workman R, Capron A, Oates JA: Release of prostaglandin D2 into human airways during acute antigen challenge. N Engl J Med 315:800 (1986).
11. Panettieri RA, Murray RK, Eszterhas AJ, Bilgen G, Martin JG: Repeated allergen inhalations induce DNA synthesis in airway smooth muscle and epithelial cells in vivo. Am J Physiol 274:L417 (1998).
12. Hershenson MB, Garland A, Kelleher MD, Zimmermann A, Hernandez C, Solway J. Hyperoxia induced airway remodeling in immature rats: Correlation with airway responsiveness. Am Rev Respir Dis 146: 1294 (1992).
13. Solway J, Hershenson MB: Structural and functional abnormalities of the airways of hyperoxia-exposed immature rats. Chest 107:89S (1995).
14. Lew DB, Songu-Mize E, Pontow SE, Stahl PD, Rattazzi MC: A mannose receptor mediates mannosyl-rich glycoprotein-induced mitogenesis in bovine airway smooth muscle cells. J Clin Invest 94:1855 (1994).
15. Lew DB, Nebigil C, Malik KU: Dual regulation by cAMP of β-hexosaminidase-induced mitogenesis in bovine tracheal myocytes. Am J Respir Cell Mol Biol 7:614 (1992).
16. Lew DB, Brown ER, Dempsey BK, Wright HM, Malik KU: Contribution of PKC to β-hexosaminidase-induced airway smooth muscle proliferation. Am J Physiol 272 (Lung Cell Mol Physiol 16):L639 (1997).
17. Tomlinson PR, Wilson JW, Stewart AG: Salbutamol inhibits the proliferation of human airway smooth muscle cells grown in culture: relationship to elevated cAMP levels. Biochem Pharmacol 49:1809 (1995).
18. Stewart AG, Fernandes D, Tomlinson PR: The effect of glucocorticoids on proliferation of human cultured airway smooth muscle. Br J Pharmacol 116:3219 (1995).
19. Redington AE, Springall DR, Meng QH, Tuck AB, Holgate ST, Polak JM, Howarth PH: Immunoreactive endothelin in bronchial biopsy specimens: increased expression in asthma and modulation by corticosteroid therapy. J Allergy Clin Immunol 100:544 (1997).
20. Sont JK, van Krieken JH, van Klink HC, Roldaan AC, Apap CR, Willems LN, Sterk PJ: Enhanced expression of neutral endopeptidase (NEP) in airway epithelium in biopsies from steroid-versus nonsteroid-treated patients with atopic asthma. Am J Respir Cell Mol Biol 16:549 (1997).
21. Sont JK, Han J, van Krieken JM, Evertse CE, Hooijer R, Willems LN, Sterk PJ: Relationship between inflammatory infiltrate in bronchial biopsy specimens and clinical severity of asthma in patients treated with inhaled steroids. Thorax 51:496 (1996).
22. Olivieri D, Chetta A, Del Donno M, Bertorelli G, Casalini A, Pesci A, Testi R, Foresi A: Effect of short-term treatment with low-dose inhaled fluticasone propionate on airway inflammation and remodeling in mild asthma: a placebo-controlled study. Am J Respir Crit Care Med 255:1864 (1997).
23. Mossman T: Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays. J Immunol Methods 65:55 (1983).
24. Lew DB, Davis S, Chodimella V, Murlas C: Guinea pig ozone-induced airway hyperreactivity is associated with increased N-Acetyl-β-Hexosaminidase (NAGA) activity in bronchoalveolar fluid. Lung 168: 273 (1990).
25. Auphan N, DiDonato JA, Rosette C, Helmberg A, Karin M: Immunosuppression by glucocorticoids: inhibition of NF-kB activity through induction of IkB synthesis. Science 270:286 (1995).
26. Scheinman RI, Cogswell PC, Lofquist AK, Baldwin AS Jr: Role of transcriptional activation of IkBa in mediation of immunosupression by glucocorticoids. Science 270:283 (1995).
27. Spahn JD, Leung YM: The role of glucocorticoids in the management of asthma. Allergy Asthma Proc 17: 341 (1996).
28. Katsunuma T, Mak JC, Barnes PJ: Glucocorticoids reduce tachykinin NK2 receptor expression in bovine tracheal smooth muscle. Eur J Pharmacol 344:99 (1998).
29. Mak JCW, Nishikawa M, Barnes PJ: Glucocorticosteroids increase β2-adrenergic receptor transcription in human lung. Am J Physiol 268:L41 (1995).
30. Pierce RA, Mariencheck WI, Sandefur S, Crouch EC, Parks WC: Glucocorticoids upregulate tropoelastin expression during late stages of fetal lung development. Am J Physiol 268-L491 (1995).
31. Bian XP, Seidler FJ, Slotkin TA: Promotional role for glucocorticoids in the development of intracellular signalling: enhanced cardiac and renal adenylate cyclase reactivity to β-adrenergic and non-adrenergic stimuli after low-dose fetal dexamethasone exposure. J Develop Physiol 17:289 (1992).
32. Nakano T, Raines EW, Abrahams JA, Wenzel FG, Higashiyama S, Klagsbrun M, Ross R. Glucocorticoid inhibits thrombin-induced expression of platelet-derived growth factor A-chain and heparin-binding epidermal growth factor-like growth factor in human aortic smooth muscle cells. J Biol Chem 268:22941 (1993).
33. Haigh RM, Jones CT, Milligan G: Glucocorticoids regulate the amount of G proteins in rat aorta. J Endocrinol 5:185 (1990).
34. Collado-Escobar D, Ali H, Beaven MA: On the mechanism of action of dexamethasone in a rat mast cell line (RBL-2H3 cells) evidence for altered coupling of receptors and G-proteins. J Immunol 144:3449 (1990).
35. Lew DB, Dempsey BK, Malik KU: Interaction of airway smooth muscle mannose receptor and VLA5 integrin via pertussis toxin sensitive mechanism (abstract). Pediatr Res 43:8A (1998).