Sex hormone-induced mammary carcinogenesis in female Noble rats: The role of androgens

Carcinogenesis

Volumn 20, Issue 8, 1999, Pages 1597-1606

  Xie, B ^a   Tsao, S W ^a   Wong, Y C ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN RECEPTOR; ESTRADIOL; ESTROGEN; FLUTAMIDE; TESTOSTERONE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BREAST CANCER; BREAST CARCINOGENESIS; FEMALE; LATENT PERIOD; MAMMARY GLAND; NONHUMAN; PRIORITY JOURNAL; RAT; STROMA CELL;

ANIMALS; ESTRADIOL; FEMALE; KI-67 ANTIGEN; MAMMARY GLANDS, ANIMAL; MAMMARY NEOPLASMS, EXPERIMENTAL; NEOPLASMS, HORMONE-DEPENDENT; RATS; RATS, INBRED STRAINS; RECEPTORS, ANDROGEN; RECEPTORS, ESTROGEN; TESTOSTERONE;

EID: 0032841099     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/20.8.1597     Document Type: Article

References (50)

1. Parker, S.L., Tong, T., Bolden, S. and Wingo, P.A. (1997) Cancer statistics 1997. CA Cancer J. Clin., 47, 5-27.
2. Boyle, P. and Leake, R. (1988) Progress in understanding breast cancer: epidemiological and biological interactions. Breast Cancer Res. Treat., 11, 91-112.
3. Dickson, R.B. and Lippman, M.E. (1987) Estrogenic regulation of growth and polypeptide growth factor secretion in human breast carcinoma. Endocr. Rev., 8, 29-43.
4. Horwitz, K.B. and McGuire, W.L. (1978) Nuclear mechanism of estrogen action. Effect of estradiol and anti-estrogens on estrogen receptors and nuclear receptor processing. J. Biol. Chem., 253, 8185-8191.
5. Rochefort, H. and Garcia, M. (1983) The estrogenic and antiestrogenic activites of androgens in female target tissues. Pharmacol. Ther., 23, 193-216.
6. Kesey, J.L. (1993) Breast cancer epidemiology: summary and future directions. Epidemiol. Rev., 15, 256-263.
7. Berrino, F., Muti, P., Micheli, A., Bolelli, G., Krogh, V., Sciajno, R., Pisani, P., Panico, S. and Secreto, G. (1996) Serum sex hormone levels after menopause and subsequent breast cancer. J. Natl Cancer Inst., 88, 291-296.
8. Bernstein, L. and Ross, R.K. (1993) Endogenous hormones and breast cancer risk. Epidemiol. Rev., 15, 48-65.
9. Secreto, G., Toniolo, P., Berrino, F., Recchione, C., Cavalleri, A., Pisani, P., Totis, A., Fariselli, G. and Di Pietro, S. (1991) Serum and urinary androgens and risk of breast cancer in postmenopausal women. Cancer Res., 51, 2572-2576.
10. Veronesi, U. and Pizzocaro, G. (1968) Breast cancer in women subsequent to cystic disease of the breast. Surg. Gynecol. Obstet., 126, 529-532.
11. Secreto, G., Toniolo, P., Berrino, F., Recchione, C., Pietro, S.D., Fariselli, G. and Decarli, A. (1984) Increased androgen activity and breast cancer risk in premenopausal women. Cancer Res., 44, 5902-5905.
12. Hill, P., Garbaczewski, L., Kasumi, F., Kuno, K., Helman, P. and Wynder, E.L. (1981) Breast cancer: diet and hormone metabolism. In Pike, M.C., Siiteri, P.K. and Welsh, C.W. (eds) Hormones and Breast Cancer, Banbury Report. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, Vol. 8, pp. 257-266.
13. Hill, P., Garbaczewski, L. and Kasumi, F. (1985) Plasma testosterone and breast cancer. Eur. J. Cancer Clin. Oncol., 21, 1265-1266.
14. Dorgan, J.F., Longcope, C., Stephenson, H.E.Jr, Falk, R.T., Miller, R., Franz, C., Kahle, L., Campbell, W.S., Tangrea, J.A. and Schatzkin, A. (1997) Serum sex hormone levels are related to breast cancer risk in postmenopausal women. Environ. Health Perspect., 105 (suppl.), 583-585.
15. Ruizeveld de Winter, J.A., Trapman, J., Vermey, M., Mulder, E., Zegers, N.D. and van der Kwast, T.H. (1991) Androgen receptor expression in human tissues: an immunohistochemical study. J. Histochem. Cytochem., 39, 927-936.
16. Janssen, P.J., Brinkmann, A.O., Boersma, W.J. and van der Kwast, T.H. (1994) Immunohistochemical detection of the androgen receptor with monoclonal antibody F39.4 in rountinely processed, paraffin-embedded human tissues after microwave pre-treatment. J. Histochem. Cytochem., 42, 1169-1175.
17. Kimura, N. and Mizokami, A. (1994) Immunocytochemical localization of androgen receptor with polyclonal antibody in paraffin-embedded human tissues. J. Histochem. Cytochem., 42, 126.
18. Wong, Y.C., Xie, B. and Tsao, G.S.W. (1999) Induction of breast cancer in Noble rats with a combination of estrogen and testosterone. In Li, J.J., Daling, J. and Li, S.A. (eds) Hormonal Carcinogenesis III. Springer-Verlag, New York, NY, in press.
19. Liao, D.J., Hou, X., Pantazis, C., Bai, S., Li, S.A. and Li, J.J. (1998) Combined treatment of estrogen and androgen is more effective than estrogen alone in induction of mammary adenocarcinoma in the male Noble rat. Proc. Am. Assoc. Cancer Res., 39, 387.
20. Xie, B., Tsao, S.W. and Wong, Y.C. (1999) Induction of high incidence of mammary tumor in female Noble rats with a combination of 17β-oestradiol and testosterone. Carcinogenesis, 20, 1069-1078.
21. Liao, D.J., Pantazis, C.G., Hou, X. and Li, S.A. (1998) Promotion of estrogen-induced mammary gland carcinogenesis by androgen in the male Noble rat: probable mediation by steroid receptor. Carcinogenesis, 19, 2173-2180.
22. Yager, J.D. and Liehr, J.G. (1996) Molecular mechanisms of estrogen carcinogenesis. Annu. Rev. Pharmacol. Toxicol., 36, 203-232.
23. Zhu, B.T. and Conney, A.H. (1998) Functional role of estrogen metabolism in target cells: review and perspectives. Carcinogenesis, 19, 1-27.
24. Yu, F.L., Bender, W., Zhang, W.Y. and Wang, M.Y. (1998) The transcriptional effects and DNA-binding specificities of 17β-estradiol after dimethyldioxirane activation. Carcinogenesis, 19, 1127-1131.
25. Yu, F.L., Wang, M.Y. and Bender, W. (1999) Evidence for an initiation mechanism of 17β-estradiol carcinogenesis. In Li, J.J., Daling, J. and Li, S.A. (eds) Hormonal Carcinogenesis III. Springer-Verlag, New York, NY, in press.
26. Rosen, P.P. (1997) Rosen's Breast Pathology. Lippincott Raven, New York, NY.
27. Jacobs, T.W., Prioleau, J.E., Stillman, I.E. and Schnitt, S.J. (1996) Loss of tumor marker-immunostaining intensity on stored paraffin slides of breast cancer. J. Natl Cancer Inst., 88, 1054-1059.
28. Wang, Z.M., Deurenberg, P., Guo, S.S., Pietrobelli, A., Wang, J., Pierson, R.N.Jr and Heymsfield, S.B. (1998) Six-compartment body composition model: inter-method comparisons of total body fat measurement. Int. J. Obes., 22, 329-337.
29. SPSS Inc. (1996) SPSS Base 7.0 for Windows User's Guide. SPSS Inc., Chicago, IL.
30. Bryan, R.M., Mercer, R.J., Bennett, R.C., Rennie, G.C, Lie, T.H. and Morgan, F.J. (1984) Androgen receptors in breast cancer. Cancer, 54, 2436-2440.
31. Soreide, J.A., Lea, O.A., Varhaug, J.E., Skarstein, A. and Kvinnsland, S. (1992) Androgen receptors in operable breast cancer: relation to other steroid hormone receptors, correlation to prognostic factors and predictive value for effect of adjuvant tamoxifen treatment. Eur. J. Surg. Oncol., 18, 112-118.
32. Lea, O.A., Kvinnsland, S. and Thorsen, T. (1989) Improved measurement of androgen receptors in human breast cancer. Cancer Res., 49, 7162-7167.
33. Colerangle, J.B. and Roy, D. (1997) Profound effects of the weak environmental estrogen-like chemical Bisphenol A on the growth of the mammary gland of Noble rats. J. Steroid Biochem. Mol. Biol., 60, 153-160.
34. Cutts, J. (1964) Estrone-induced mammary tumors in the rat. Effects of alterations in the hormonal environment on tumor induction, behavior, and growth. Cancer Res., 24, 1124-1130.
35. Visser, M., Gallagher, D., Deurenberg, P., Wang, J., Pierson, R.N.Jr and Heymsfield, S.B. (1997) Density of fat-free body mass: relationship with race, age, and level of body fatness. Am. J. Physiol., 212, E781-E787.
36. Stampfer, M. and Yaswen, P. (1993) Culture systems for study of human mammary epithelial cell proliferation, differentiation and transformation. Cancer Surv., 18, 7-34.
37. Xie, B., Tsao, S.W. and Wong, Y.C. (1999) Sex hormone-induced mammary-carcinogenesis in the female Noble rat: expression of TGF-β1 and its receptors, TGF-α, and EGF-R in mammary carcinogenesis. Breast Cancer Res. Treat., in press.
38. Wakefield, L.M., Letterio, J.J., Geiser, A.G., Flanders, K.C., O'Shaughnessy, J., Roberts, A.B. and Sporn, M.B. (1995) Transforming growth factor αs in mammary tumorigenesis: promoters or antipromoters? In McClain, R.M., Slaga, T.J., LeBoeuf, R. and Pitot, H. (eds) Growth Factors and Tumor Promotion: Implications for Risk Assessment. Willy-Liss, New York, NY, pp. 133-148.
39. Drife, J.O. (1986) Breast development in puberty. Ann. N.Y. Acad. Sci., 464, 58-65.
40. Cunha, G.R. (1994) Role of mesenchymal-epithelial interactions in normal and abnormal development of the mammary gland and prostate. Cancer, 74, 1030-1044.
41. Dickson, R.B. and Lippman, M.E. (1995) Growth factors in breast cancer. Endocr. Rev., 16, 559-589.
42. Hayward, S.W., Rosen, M.A. and Cunha, G.R. (1997) Stromal-epithelial interactions in the normal and neoplastic prostate. Br. J. Urol., 79, 1-9.
43. Wang, Y.Z. and Wong, Y.C. (1998) Sex hormone-induced prostatic carcinogenesis in the Noble rat: the role of insulin-like growth factor-I (IGF-I) and vascular endothelial growth factor (VEGF) in the development of prostate cancer. Prostate, 35, 165-177.
44. Ronnov-Jessen, L., Peterson, O. and Bissell, M. (1996) Cellular changes involved in conversion of normal to malignant breast: importance of the stromal reaction. Physiol. Rev., 76, 69-125.
45. Bosman, F.T., de Bruine, A. and Flohil, C. (1993) Epithelial-stromal interactions in colon cancer. Int. J. Dev. Biol., 37, 203-211.
46. Cunha, G.R., Hayward, S.W., Dahiya, R. and Foster, B.A. (1996) Smooth muscle-epithelial interactions in normal and neoplastic prostatic development. Acta Anat., 155, 63-72.
47. Tremblay, G. (1979) Stromal aspects of breast carcinoma. Exp. Mol. Pathol., 31, 248-260.
48. Van de Hooff, A. (1988) Stromal invovement in malignant growth. Adv. Cancer Res., 50, 159-196.
49. Johnston, P.G., Rondinone, C.M., Voeller, D. and Allegra, C.J. (1992) Identification of protein factor secreted by 3T3-L1 preadipocytes inhibitory for the human MCF-7 breast cancer cell line. Cancer Res., 52, 6860-6865.
50. Taylor-Papadimitrious J., Berdichevsky, F., D'Souza, B. and Burchell, J. (1993) Human models of breast cancer. Cancer Surv., 16, 59-78.