Neuron-enriched second trimester human cultures: Growth factor response and in vivo graft survival

Cell Transplantation

Volumn 8, Issue 1, 1999, Pages 59-73

  White, Michael G ^a   Hammond, Robert R ^b   Sanders, Virginia J ^c   Bonaroti, Eugene A ^a   Mehta, Anil P ^a   Wang, Guoji ^a   Wiley, Clayton A ^a   Achim, Cristian L ^a,d  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF WESTERN ONTARIO   (Canada)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

Author keywords

Human; Neuron; Neurotrophic; Precursor; Transplantation

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR; NEUROTROPHIC FACTOR; SCATTER FACTOR; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ARTICLE; ASTROCYTE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DEGENERATIVE DISEASE; GLIA CELL; GRAFT SURVIVAL; HUMAN; HUMAN CELL; IN VIVO STUDY; MALE; MOUSE; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; STEM CELL; XENOGRAFT;

ANIMALIA;

EID: 0032840363     PISSN: 09636897     EISSN: None     Source Type: Journal    
DOI: 10.1177/096368979900800115     Document Type: Article

References (51)

1. Achim, C. L.; Katyal, S.; Wiley, C. A.; Shiratori, M.; Wang, G.; Oshika, E.; Petersen, B. E.; Li, J. M.; Michalopoulos, G. K. Expression of HGF and cMet in the developing and adult brain. Brain Res. Dev. Brain Res. 102: 299-303; 1997.
2. Achim, C. L.; Miners, D. K.; Burrola, P. G.; Martin, F. C.; Wiley, C. A. In vivo model of HIV infection of the human brain. Dev. Neurosci. 15:423-432; 1993.
3. Baetge, E. E. Neural stem cells for CNS transplantation. Ann. NY Acad. Sci. 695:285-291; 1993.
4. Bjorklund, A.; Stenevi, U. Reconstruction of the nigrostriatal pathway by intracerebral nigral transplants. J. Neurosurg. 72:231-244; 1979.
5. Branch, D. W.; Ducat, L.; Fantel, A.; Low, W. C.; Zhou, F. C.; Dayton, D. H.; Gill, T. R. Suitability of fetal tissues from spontaneous abortions and from ectopic pregnancies for transplantation. Human Fetal Tissue Working Group. JAMA 273:66-68; 1995.
6. Cory, A. H.; Owen, T. C.; Barltrop, J. A.; Cory, J. G. Use of an aqueous soluble tetrazolium/formazan assay for cell growth assays in culture. Cancer Commun. 3:207-212; 1991.
7. Deacon, T.; Dinsmore, J.; Costantini, L. C.; Ratliff, J.; Isacson, O. Blastula-stage stem cells can differentiate into dopaminergic and serotonergic neurons after transplantation. Exp. Neurol. 149:28-41; 1998.
8. Ebens, A.; Brose, K.; Leonardo, E. D.; Hanson, M. G., Jr.; Bladt, F.; Birchmeier, C.; Barres, B. A.; Tessier-Lavigne, M. Hepatocyte growth factor/scatter factor is an axonal chemoattractant and a neurotrophic factor for spinal motor neurons. Neuron 17:1157-1172; 1996.
9. Espejo, E. F.; Montoro, R. J.; Armengol, J. A.; Lopez-Barneo, J. Cellular and functional recovery of Parkinsonian rats after intrastriatal transplantation of carotid body cell aggregates. Neuron 20:197-206; 1998.
10. Fisher, L. J. Neural precursor cells: Applications for the study and repair of the central nervous system. Neurobiol. Dis. 4:1-22; 1997.
11. Freeman, T. B.; Olanow, C. W.; Hauser, R. A.; Nauert, G. M.; Smith, D. A.; Borlongan, C. V.; Sanberg, P. R.; Holt, D. A.; Kordower, J. H.; Vingerhoets, J. G.; Snow, B. J.; Calne, D.; Gauger, L. I. Bilateral fetal nigral transplantation into the postcommissural putamen in parkinsons-disease. Ann. Neurol. 38:379-388; 1995.
12. Gage, F. H. Cell therapy. Nature 392:18-24; 1998.
13. Hefti, F. Neurotrophic factor therapy for nervous system degenerative diseases. J. Neurobiol. 25:1418-1435; 1994.
14. Hefti, F. Neurotrophic factor therapy - keeping score. Nat. Med. 3:497-498; 1997.
15. Henderson, B. T.; Clough, C. G.; Hughes, R. C.; Hitchcock, E. R.; Kenny, B. G. Implantation of human fetal ventral mesencephalon to the right caudate nucleus in advanced Parkinson's disease. Arch. Neurol. 48:822-827; 1991.
16. Hirka, G.; Prakash, K.; Kawashima, H.; Plotkin, S. A.; Andrews, P. W.; Gonczol, E. Differentiation of human embryonal carcinoma cells induces human immunodeficiency virus permissiveness which is stimulated by human cytomegalovirus coinfection. J. Virol. 65:2732-2735; 1991.
17. Johe, K. K.; Hazel, T. G.; Muller, T.; Dugich-Djordjevic, M. M.; McKay, R. D. Single factors direct the differentiation of stem cells from the fetal and adult central nervous system. Genes Dev. 10:3129-3140; 1996.
18. Kempermann, G.; Kuhn, H. G.; Gage, F. H. Experience-induced neurogenesis in the senescent dentate gyrus. J. Neurosci. 18:3206-3212; 1998.
19. Kordower, J. H.; Freeman, T. B.; Snow, B. J.; Vingerhoets, F. J.; Mufson, E. J.; Sanberg, P. R.; Hauser, R. A.; Smith, D. A.; Nauert, G. M.; Perl, D. P.; Olanow, C. W. Neuropathological evidence of graft survival and striatal reinnervation after the transplantation of fetal mesencephalic tissue in a patient with Parkinson's disease. N. Engl. J. Med. 332:1118-1124; 1995.
20. Lindvall, O.; Widner, H.; Rehncrona, S.; Brundin, P.; Odin, P.; Gustavii, B.; Frackowiak, R.; Leenders, K. L.; Sawle, G.; Rothwell, J. C.; Bjorklund, A.; Marsden, C. D. Transplantation of fetal dopamine neurons in Parkinson's disease: One-year clinical and neurophysiological observations in two patients with putaminal implants. Ann. Neurol. 31:155-165; 1992.
21. Lundberg, C.; Winkler, C.; Whittemore, S.; Bjorklund, A. Conditionally immortalized neural progenitor cells grafted to the striatum exhibit site-specific neuronal differentiation and establish connections with the host globulus pallidus. Neurobiol. Dis. 3:33-50; 1996.
22. Madrazo, I.; Franco, B. R.; Ostrosky, S. F.; Aguilera, M.; Cuevas, C.; Alvarez, F.; Magallon, E.; Zamorano, C.; Morelos, A. Neural transplantation (auto-adrenal, fetal nigral and fetal adrenal) in Parkinson's disease: The Mexican experience. Prog. Brain Res. 82:593-602; 1990.
23. Magaud, J. P.; Sargent, I.; Mason, D. Y. Detection of human white cell proliferative responses by immunoenzymatic measurement of bromodeoxyuridine uptake. J. Immunol. Methods 106:95-100; 1988.
24. Martin, F.; Wiley, C. An alternative method for obtaining high-viability cell suspensions from neonatal mouse brain. J. Neurosci. Methods 55:99-104; 1994.
25. Martin, F. C.; Wiley, C. A. A serum-free, pyruvate-free medium that supports neonatal neural/glial cultures. J. Neurosci. Res. 41:246-258; 1994.
26. Marty, S.; Berninger, B.; Carroll, P.; Thoenen, H. GABAergic stimulation regulates the phenotype of hippocampal interneurons through the regulation of brain-derived neurotrophic factor. Neuron 16:565-570; 1996.
27. Marty, S.; Carroll, P.; Cellerino, A.; Castren, E.; Staiger, V.; Thoenen, H.; Lindholm, D. Brain-derived neurotrophic factor promotes the differentiation of various hippocampal nonpyramidal neurons, including Cajal-Retzius cells, in organotypic slice cultures. J. Neurosci. 16:675-687; 1996.
28. Mattson, M. P.; Rychlik, B. Comparison of rates of neuronal development and survival in human and rat cerebral cortical cell cultures. Mech. Ageing Dev. 60:171-187; 1991.
29. Mattson, M. P.; Rychlik, B.; You, J. S.; Sisken, J. E. Sensitivity of cultured human embryonic cerebral cortical neurons to excitatory amino acid-induced calcium influx and neurotoxicity. Brain Res. 542:97-106; 1991.
30. McKay, R. D. The origins of cellular diversity in the mammalian central nervous system. Cell 58:815-821; 1989.
31. Milbrandt, J.; de Sauvage, F. J.; Fahrner, T. J.; Baloh, R. H.; Leitner, M. L.; Tansey, M. G.; Lampe, P. A.; Heuckeroth, R. O.; Kotzbauer, P. T.; Simburger, K. S.; Golden, J. P.; Davies, J. A.; Vejsada, R.; Kato, A. C.; Hynes, M.; Sherman, D.; Nishimura, M.; Wang, L. C.; Vandlen, R.; Moffat, B.; Klein, R. D.; Poulsen, K.; Gray, C.; Garces, A.; Henderson, C. E.; Phillips, H. S.; Johnson, E. M., Jr. Persephin, a novel neurotrophic factor related to GDNF and neurturin. Neuron 20:245-253; 1998.
32. Muir, D.; Varon, S.; Manthorpe, M. An enzyme-linked immunosorbent assay for bromodeoxyuridine incorporation using fixed microcultures. Anal. Biochem. 185:377-382; 1990.
33. Ohga, Y.; Zirrgiebel, U.; Hamner, S.; Michaelidis, T. M.; Cooper, J.; Thoenen, H.; Lindholm, D. Cell density increases Bcl-2 and Bcl-x expression in addition to survival of cultured cerebellar granule neurons. Neuroscience 73: 913-917; 1996.
34. Olanow, C. W.; Kordower, J. H.; Freeman, T. B. Fetal nigral transplantation as a therapy for Parkinson's disease. Trends Neurosci. 19:102-109; 1996.
35. Perlow, M. J.; Freed, W. J.; Hoffer, B. J.; Seiger, A.; Olson, L.; Wyatt, R. J. Brain grafts reduce motor abnormalities produced by destruction of nigrostriatal dopamine system. Science 204:643-647; 1979.
36. Pincus, D. W.; Keyoung, H. M.; Harrison-Restelli, C.; Goodman, R. R.; Fraser, R. A.; Edgar, M.; Sakakibara, S.; Okano, H.; Nedergaard, M.; Goldman, S. A. Fibroblast growth factor-2/brain-derived neurotrophic factor-associated maturation of new neurons generated from adult human subependymal cells. Ann. Neurol. 43:576-585; 1998.
37. Ray, J.; Gage, F. H. Spinal cord neuroblasts proliferate in response to basic fibroblast growth factor. J. Neurosci. 14: 3548-3564; 1994.
38. Redmond, D. E., Jr.; Leranth, C.; Spencer, D. D.; Robbins, R.; Vollmer, T.; Kim, J. H.; Roth, R. H.; Dwork, A. J.; Naftolin, F. Fetal neural graft survival. Lancet 336: 820-822; 1990.
39. Reynolds, B. A.; Tetzlaff, W.; Weiss, S. A multipotential EGF-responsive striatal embryonic progenitor cell produces neurons and astrocytes. J. Neurosci. 12:4565-4574; 1992.
40. Reynolds, B. A.; Weiss, S. Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system. Science 255:1707-1710; 1992.
41. Rosenthal, A. Auto transplants for Parkinson's disease? Neuron 20:169-172; 1998.
42. Sanders, V. J.; Mehta, A. P.; White, M. G.; Achim, C. L. A murine model of HIV encephalitis: Xenotransplantation of HIV infected human neuroglia into SCID mouse brain. Neuropathol. Appl. Neurobiol. 24:461-467; 1998.
43. Sladek, J. R. J. C.; Timothy, J.; Elsworth, J. D.; Roth, R. H.; Taylor, J. R.; Redmond, D. E., Jr. Intrastriatal grafts from multiple donors do not result in a proportional increase in survival of dopamine neurons in nonhuman primates. Cell Transplant. 7:87-96; 1998.
44. Snyder, E. Y.; Deitcher, D. L.; Walsh, C.; Arnold, A. S.; Hartwieg, E. A.; Cepko, C. L. Multipotent neural cell lines can engraft and participate in development of mouse cerebellum. Cell 68:33-51; 1992.
45. Spencer, D. D.; Robbins, R. J.; Naftolin, F.; Marek, K. L.; Vollmer, T.; Leranth, C.; Roth, R. H.; Price, L. H.; Gjedde, A.; Bunney, B. S.; Sass, K. J.; Elsworth, J. D.; Kier, E. L.; Makuch, R.; Hoffer, P. B.; Redmond, D. E., Jr. Unilateral transplantation of human fetal mesencephalic tissue into the caudate nucleus of patients with Parkinson's disease. N. Engl. J. Med. 327:1541-1548; 1992.
46. Studer, L.; Tabar, V.; McKay, R. D. G. Transplantation of expanded mesencephalic precursors leads to recovery in parkinsonian rats. Nat. Neurosci. 1:290-295; 1998.
47. Temple, S.; Qian, X. M. Bfgf, neurotrophins, and the control of cortical neurogenesis. Neuron 15:249-252; 1995.
48. Trojanowski, J. Q.; Kleppner, S. R.; Hartley, R. S.; Miyazono, M.; Fraser, N. W.; Kesari, S.; Lee, V. M. Transfectable and transplantable postmitotic human neurons: A potential "platform" for gene therapy of nervous system diseases. Exp. Neurol. 144:92-97; 1997.
49. Vescovi, A. L.; Reynolds, B. A.; Fraser, D. D.; Weiss, S. bFGF regulates the proliferative fate of unipotent (neuronal) and bipotent (neuronal/astroglial) EGF-generated CNS progenitor cells. Neuron 11:951-966; 1993.
50. Ye, W.; Shimamura, K.; Rubenstein, J. L.; Hynes, M. A.; Rosenthal, A. FGF and Shh signals control dopaminergic and serotonergic cell fate in the anterior neural plate. Cell 93:755-766; 1998.
51. Zhou, X. F.; Rush, R. A. Localization of neurotrophin-3-like immunoreactivity in the rat central nervous system. Brain Res. 643:162-172; 1994.