Natural human interferon-α administered orally as a treatment of bovine respiratory disease complex

Journal of Interferon and Cytokine Research

Volumn 19, Issue 8, 1999, Pages 907-910

  Cummins, Joseph M ^a   Guthrie, Dan ^a   Hutcheson, David P ^b   Krakowka, Steven ^c   Rosenquist, Bruce D ^a  

^a Amarillo Biosciences Inc   (United States)

^b Animal Agricultural Consulting   (United States)

^c OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; INTERFERON; PLACEBO;

ANIMAL DISEASE; ANIMAL MODEL; ARTICLE; CATTLE; CONTROLLED STUDY; DOSE RESPONSE; IMMUNOTHERAPY; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RESPIRATORY DISTRESS; TREATMENT OUTCOME; WEIGHT GAIN;

ADMINISTRATION, ORAL; ANALYSIS OF VARIANCE; ANIMALS; ANTIVIRAL AGENTS; CATTLE; CATTLE DISEASES; DISEASE OUTBREAKS; DRUG ADMINISTRATION SCHEDULE; HUMANS; INTERFERON-ALPHA; RESPIRATORY TRACT INFECTIONS; UNITED STATES;

ANIMALIA; BOS TAURUS; BOVINAE;

EID: 0032840244     PISSN: 10799907     EISSN: None     Source Type: Journal    
DOI: 10.1089/107999099313442     Document Type: Article

References (16)

1. JENSEN, R., and MACKAY, G.R. (1979). Shipping Fever Pneumonia. In: Diseases of Feedlot Cattle, 3rd ed. Philadelphia: Lea & Febiger, pp. 59-65.
2. WIKSE, S.E. (1985). Feedlot Cattle Pneumonias. Vet Clinics N. Am: Food Animal Pract. 1, 289-310.
3. CUMMINS, J.M. (1983). Feedlot Diseases and Parasites. In: The Feedlot, 3rd ed. G.B. Thompson and C.C. O'Mary (eds.) Philadelphia: Lea & Febiger, pp. 185-195.
4. ARMSTRONG, M.A., PERERIA, H.G., and ANDREWES, C.H. (1961). Observations on the virus of infectious bovine rhinotracheitis and its affinity with the herpes virus group. Virology 14, 276-285.
5. ROSENQUIST, B.D., and LOAN, R.W. (1969). Interferon induction in the bovine species by infectious bovine rhinotracheitis virus. Am. J. Vet. Res. 30, 1305-1312.
6. CUMMINS, J.M., and ROSENQUIST, B.D. (1977). Effect of hydrocortisone on the interferon response of calves infected with infectious bovine rhinotracheitis virus. Am. J. Vet. Res. 38, 1163-1166.
7. AHL, R., and STRAUB, O.C. (1971). Die lokale interferonbildung im respirations - und genital trakt nach experimenteller infektionmit rhinotracheitis (IBR) - und blaschenausschlag (IPV) - virus. Dtsch. Tierarztl Wschr. 78, 653-655.
8. STRAUB, O.C., and AHL, R. (1976). Lokale interferonbildung beim rind nach intranasaler infektion mit avirulentem IBR/IPV-virus und maulund klauenseuche-virus. Zbl. Vet. Med. 23, 470-482.
9. TODD, J.D., VOLENIC, F.J., and PATON, I.M. (1972). Interferon in nasal secretions and sera of calves after intranasal administration of a virulent infectious bovine rhinotracheitis virus: association of interferon in nasal secretions with early resistance to challenge with virulent virus. Infect. Immun. 5, 699-706.
10. ZYGRAICH, N., LOBMANN, M., VASCOBOINIC, E., BERGE, E., and HUYGELEN, C. (1974). In vivo and in vitro properties of a temperature sensitive mutant of infectious bovine rhinotracheitis virus. Res. Vet Sci. 16, 328-335.
11. GERBER, J.D., MARRON, A.E., and KUCERA, C.J. (1978). Local and systemic cellular and antibody immune responses of cattle to infectious bovine rhinotracheitis virus vaccines administered intranasally or intramuscularly. Am. J. Vet. Res. 39, 753-760.
12. SAVAN, M., ANGULO, A.B., and DERBYSHIRE, J.B. (1979). Interferon, antibody responses and protein induced by an intranasal infectious bovine rhinotracheitis vaccine. Can. Vet. J. 20, 207-210.
13. CANTELL, K., HIRVONEN, S., and KOISTINEN, V. (1981). Partial purification of human leukocyte interferon on a large scale. Methods Enzymol. 78, 499-505.
14. SAS. (1997). SAS User's Guide: Statistics. Cary, NC: SAS Institute, Inc.
15. CUMMINS, J.M., HUTCHESON, D.P., CUMMINS, M.J., GEORGIADES, J.A., and RICHARDS, A.B. (1993). Oral therapy with human interferon alpha in calves experimentally injected with infectious bovine rhinotracheitis virus. Arch. Immunol. Ther. Exp. 41, 193-197.
16. MOORE, B.R., KRAKOWKA, S., CUMMINS, J.M., and ROBERTSON, J.T. (1996). Changes in airway inflammatory cell populations in standardbred racehorses after interferon-alpha administration. Vet. Immunol. Immunopath. 49, 347-358.