MMP inhibition reduces intimal hyperplasia in a human vein graft stenosis model

Annals of the New York Academy of Sciences

Volumn 878, Issue , 1999, Pages 547-550

  Loftus, Ian Mr ^a,b   Porter, K ^a   Peterson, M ^a   Boyle, J ^a   London, N J M ^a   Bell, P R F ^a   Thompson, M M ^a  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

^b LEICESTER ROYAL INFIRMARY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DOXYCYCLINE; GELATINASE A; GELATINASE B; MARIMASTAT; MATRIX METALLOPROTEINASE; MATRIX METALLOPROTEINASE INHIBITOR; PROTEINASE;

CONFERENCE PAPER; CONTROLLED STUDY; HUMAN; HUMAN TISSUE; HYPERPLASIA; INTIMA; SAPHENOUS VEIN; STENOSIS;

EID: 0032839685     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1999.tb07723.x     Document Type: Conference Paper

References (5)

1. 1. Varty, K., K. Allen, P.R.F. Bell & N.J.M. London. 1993. Infrainguinal vein graft stenosis. Br. J. Surg. 80: 825-833.
2. 2. Clowes, A.W. & S.M. Schwartz. 1985. Significance of quiescent smooth muscle migration in the injured rat carotid artery. Circ. Res. 56: 139-145.
3. 3. Porter, K.E., K. Varty, L. Jones, P.R.F. Bell & N.J.M. London. 1996. Human saphenous vein organ culture: a useful model of intimal hyperplasia? Eur. J. Vasc. Endovasc. Surg. 11: 48-58.
4. 4. Allen, K.E., K. Varty, L. Jones, R.D. Sayers, P.R.F. Bell & N.J.M. London. 1994. Human venous endothelium can promote intimal hyperplasia in a paracrine manner. J. Vasc. Surg. 19: 577-584.
5. 5. Porter, K.E., M.M. Thompson, I.M. Loftus, E. McDermott, L. Jones, M. Crowther et al. 1998. Production and inhibition of the gelatinolytic matrix metalloproteinases in a human model of vein graft stenosis. Eur. J. Vasc. Endovasc. Surg. In press.