-
1
-
-
77956926559
-
Anticholinergic psychotomimetic agents
-
Abood LG and Biel JH (1962) Anticholinergic psychotomimetic agents. Int Rev Neurobiol 4:217-273.
-
(1962)
Int Rev Neurobiol
, vol.4
, pp. 217-273
-
-
Abood, L.G.1
Biel, J.H.2
-
2
-
-
0019943797
-
Pharmacological specificity of conditioned avoidance response inhibition in rats: Inhibition by neuroleptics and correlation to dopamine receptor blockade
-
Arnt J (1982) Pharmacological specificity of conditioned avoidance response inhibition in rats: Inhibition by neuroleptics and correlation to dopamine receptor blockade. Acta Pharmacol Toxicol 51:321-329.
-
(1982)
Acta Pharmacol Toxicol
, vol.51
, pp. 321-329
-
-
Arnt, J.1
-
3
-
-
0030902127
-
1-selective muscarinic agonist, on cognitive function and behavioral symptoms in Alzheimer's disease
-
1-selective muscarinic agonist, on cognitive function and behavioral symptoms in Alzheimer's disease. Arch Neurol 54:465-473.
-
(1997)
Arch Neurol
, vol.54
, pp. 465-473
-
-
Bodick, N.C.1
Often, W.W.2
Levey, A.I.3
Cutler, N.R.4
Gauthier, S.G.5
Satlin, A.6
Shannon, H.E.7
Tollefson, G.D.8
Hurley, D.J.9
Paul, S.M.10
-
4
-
-
0025736130
-
Cholinergic input to dopaminergic neurons in the substantia nigra: A double immunocytochemical study
-
Bolam JP, Francis CM and Henderson Z (1991) Cholinergic input to dopaminergic neurons in the substantia nigra: A double immunocytochemical study. Neuroscience 41:1035-1044.
-
(1991)
Neuroscience
, vol.41
, pp. 1035-1044
-
-
Bolam, J.P.1
Francis, C.M.2
Henderson, Z.3
-
5
-
-
6844260515
-
1 agonist incorporating the N-methoxy imidoyl nitrile group as a novel ester bioisostere
-
1 agonist incorporating the N-methoxy imidoyl nitrile group as a novel ester bioisostere. J Med Chem 40:4265-4280.
-
(1997)
J Med Chem
, vol.40
, pp. 4265-4280
-
-
Bromidge, S.M.1
Brown, F.2
Cassidy, F.3
Clark, M.S.4
Dabbs, S.5
Hadley, M.S.6
Hawkins, J.7
Loudon, J.M.8
Naylor, C.B.9
Orlek, B.S.10
Riley, G.J.11
-
6
-
-
0032496752
-
Xanomeline compared to other muscarinic agents on stimulation of phosphoinositide hydrolysis in vivo and other cholinomimetic effects
-
Bymaster FP, Carter PA, Peters SC, Zhang W, Ward JS, Mitch CH, Calligaro DO, Whitesitt CA, DeLapp NW, Shannon HE, Rimvall K, Jeppesen L, Sheardown MJ, Fink-Jensen A and Sauerberg P (1998a) Xanomeline compared to other muscarinic agents on stimulation of phosphoinositide hydrolysis in vivo and other cholinomimetic effects. Brain Res 79:179-190.
-
(1998)
Brain Res
, vol.79
, pp. 179-190
-
-
Bymaster, F.P.1
Carter, P.A.2
Peters, S.C.3
Zhang, W.4
Ward, J.S.5
Mitch, C.H.6
Calligaro, D.O.7
Whitesitt, C.A.8
DeLapp, N.W.9
Shannon, H.E.10
Rimvall, K.11
Jeppesen, L.12
Sheardown, M.J.13
Fink-Jensen, A.14
Sauerberg, P.15
-
7
-
-
0031786012
-
Unexpected antipsychotic-like activity with the muscarinic agonist PTAC
-
Bymaster FP, Shannon HE, Rasmussen K, DeLapp NW, Mitch CH, Ward JS, Calligaro DO, Ludvigsen TS, Sheardown MJ, Olesen PH, Swedberg MDB, Sauerberg P and Fink-Jensen AJ (1998b) Unexpected antipsychotic-like activity with the muscarinic agonist PTAC. Eur J Pharmacol 356:109-119.
-
(1998)
Eur J Pharmacol
, vol.356
, pp. 109-119
-
-
Bymaster, F.P.1
Shannon, H.E.2
Rasmussen, K.3
DeLapp, N.W.4
Mitch, C.H.5
Ward, J.S.6
Calligaro, D.O.7
Ludvigsen, T.S.8
Sheardown, M.J.9
Olesen, P.H.10
Swedberg, M.D.B.11
Sauerberg, P.12
Fink-Jensen, A.J.13
-
8
-
-
0030927142
-
Xanomeline: A selective muscarinic agonist for the treatment of Alzheimer's disease
-
Bymaster FP, Whitesitt CA, Shannon HE, DeLapp N, Ward JS, Calligaro DO, Shipley LA, Buelke-Sam JL, Bodick NC, Farde L, Sheardown MJ, Olesen PH, Hansen KT, Suzdak PD, Swedberg MDB, Sauerberg P and Mitch CH (1997) Xanomeline: A selective muscarinic agonist for the treatment of Alzheimer's disease. Drug Dev Res 40:158-170.
-
(1997)
Drug Dev Res
, vol.40
, pp. 158-170
-
-
Bymaster, F.P.1
Whitesitt, C.A.2
Shannon, H.E.3
DeLapp, N.4
Ward, J.S.5
Calligaro, D.O.6
Shipley, L.A.7
Buelke-Sam, J.L.8
Bodick, N.C.9
Farde, L.10
Sheardown, M.J.11
Olesen, P.H.12
Hansen, K.T.13
Suzdak, P.D.14
Swedberg, M.D.B.15
Sauerberg, P.16
Mitch, C.H.17
-
9
-
-
0028181720
-
1 muscarinic agonist xanomeline (LY246708/NNC11-0232)
-
1 muscarinic agonist xanomeline (LY246708/NNC11-0232). J Pharmacol Exp Ther 269:282-289.
-
(1994)
J Pharmacol Exp Ther
, vol.269
, pp. 282-289
-
-
Bymaster, F.P.1
Wong, D.T.2
Mitch, C.H.3
Ward, J.S.4
Calligaro, D.O.5
Schoepp, D.D.6
Shannon, H.E.7
Sheardown, M.J.8
Olesen, P.H.9
Suzdak, P.D.10
Sauerberg, P.11
-
10
-
-
0030943091
-
Neurotransmitter aberrations in schizophrenia: New perspectives and therapeutic implications
-
Carlsson A, Hansson LL, Waters N and Carlsson ML (1997) Neurotransmitter aberrations in schizophrenia: New perspectives and therapeutic implications. Life Sci 61:75-94.
-
(1997)
Life Sci
, vol.61
, pp. 75-94
-
-
Carlsson, A.1
Hansson, L.L.2
Waters, N.3
Carlsson, M.L.4
-
11
-
-
0013478566
-
Central cholinergic blockade of the conditioned avoidance response in rats
-
Chalmers RK and Erickson CK (1964) Central cholinergic blockade of the conditioned avoidance response in rats. Psychopharmacologia 6:31-41.
-
(1964)
Psychopharmacologia
, vol.6
, pp. 31-41
-
-
Chalmers, R.K.1
Erickson, C.K.2
-
12
-
-
0017255979
-
Dopamine receptor binding predicts clinical and pharmacological potencies of antischizophrenic drugs
-
Creese I, Burt D and Snyder SH (1976) Dopamine receptor binding predicts clinical and pharmacological potencies of antischizophrenic drugs. Science (Wash DC) 192:481-483.
-
(1976)
Science (Wash DC)
, vol.192
, pp. 481-483
-
-
Creese, I.1
Burt, D.2
Snyder, S.H.3
-
13
-
-
0027238944
-
Physostigmine ameliorates the delusions of Alzheimer's disease
-
Cummings JL, Gorman DG and Shapira J (1993) Physostigmine ameliorates the delusions of Alzheimer's disease. Biol Psychiatry 33:536-541.
-
(1993)
Biol Psychiatry
, vol.33
, pp. 536-541
-
-
Cummings, J.L.1
Gorman, D.G.2
Shapira, J.3
-
14
-
-
0017120689
-
Differential effects of neuroleptic and other psychotropic agents on acquisition of avoidance in rats
-
Davidson AB and Weidley E (1976) Differential effects of neuroleptic and other psychotropic agents on acquisition of avoidance in rats. Life Sci 18:1279-1284.
-
(1976)
Life Sci
, vol.18
, pp. 1279-1284
-
-
Davidson, A.B.1
Weidley, E.2
-
15
-
-
0017835802
-
Pharmacological investigations of the cholinergic imbalance hypothesis of movement disorders and psychosis
-
Davis KL and Berger PA (1978) Pharmacological investigations of the cholinergic imbalance hypothesis of movement disorders and psychosis. Biol Psychiatry 12: 23-49.
-
(1978)
Biol Psychiatry
, vol.12
, pp. 23-49
-
-
Davis, K.L.1
Berger, P.A.2
-
16
-
-
0019521227
-
Physostigmine and lithium in the schizophrenias
-
Edelstein P, Schultz JR, Hirschowitz J, Kanter DR and Garver DL (1981) Physostigmine and lithium in the schizophrenias. Am J Psychiatry 138:1078-1081.
-
(1981)
Am J Psychiatry
, vol.138
, pp. 1078-1081
-
-
Edelstein, P.1
Schultz, J.R.2
Hirschowitz, J.3
Kanter, D.R.4
Garver, D.L.5
-
17
-
-
0027396773
-
WAL 2014: A muscarinic agonist with preferential neuron-stimulating properties
-
Ensinger HA, Doods HN, Immel-Sehr AR, Kuhn FJ, Lambrecht G, Mendla KD, Müller RE, Mutschler E, Sagrada A, Walther G and Hammer R (1993) WAL 2014: A muscarinic agonist with preferential neuron-stimulating properties. Life Sci 52:473-480.
-
(1993)
Life Sci
, vol.52
, pp. 473-480
-
-
Ensinger, H.A.1
Doods, H.N.2
Immel-Sehr, A.R.3
Kuhn, F.J.4
Lambrecht, G.5
Mendla, K.D.6
Müller, R.E.7
Mutschler, E.8
Sagrada, A.9
Walther, G.10
Hammer, R.11
-
18
-
-
0028924310
-
Mesopontine neurons in schizophrenia
-
Garcia-Rill E, Biederman JA, Chambers T, Skinner RD, Mrak RE, Husain M and Karson CN (1995) Mesopontine neurons in schizophrenia. Neuroscience 66:321-335.
-
(1995)
Neuroscience
, vol.66
, pp. 321-335
-
-
Garcia-Rill, E.1
Biederman, J.A.2
Chambers, T.3
Skinner, R.D.4
Mrak, R.E.5
Husain, M.6
Karson, C.N.7
-
20
-
-
0031749164
-
Activation of midbrain presumed dopaminergic neurones by muscarinic cholinergic receptors: An in vivo electrophysiological study in the rat
-
Gronier B and Rasmussen K (1998) Activation of midbrain presumed dopaminergic neurones by muscarinic cholinergic receptors: An in vivo electrophysiological study in the rat. Br J Pharmacol 124:455-464.
-
(1998)
Br J Pharmacol
, vol.124
, pp. 455-464
-
-
Gronier, B.1
Rasmussen, K.2
-
21
-
-
0029914548
-
Effect of tacrine on behavioral symptoms in Alzheimer's disease: An open label study
-
Kaufer DI, Cummings JL and Christine D (1996) Effect of tacrine on behavioral symptoms in Alzheimer's disease: An open label study. J Geriatr Psychiatry Neurol 9:1-6.
-
(1996)
J Geriatr Psychiatry Neurol
, vol.9
, pp. 1-6
-
-
Kaufer, D.I.1
Cummings, J.L.2
Christine, D.3
-
22
-
-
0022386434
-
Effects of psychoactive drugs on conditioned avoidance response in Mongolian gerbils (Meriones unguiculatus): Comparison with Wistar rats and dd mice
-
Kuribara H and Tadokoro S (1985) Effects of psychoactive drugs on conditioned avoidance response in Mongolian gerbils (Meriones unguiculatus): Comparison with Wistar rats and dd mice. Pharmacol Biochem Behav 23:1013-1018.
-
(1985)
Pharmacol Biochem Behav
, vol.23
, pp. 1013-1018
-
-
Kuribara, H.1
Tadokoro, S.2
-
23
-
-
0031441919
-
1 receptors
-
1 receptors. J Pharmacol Exp Ther 283:1059-1068.
-
(1997)
J Pharmacol Exp Ther
, vol.283
, pp. 1059-1068
-
-
Loudon, J.M.1
Bromidge, S.M.2
Brown, F.3
Clark, M.S.G.4
Hatcher, J.P.5
Hawkins, J.6
Riley, G.J.7
Noy, R.G.8
Orlek, B.S.9
-
24
-
-
0026757929
-
The behavioral pharmacology of olanzapine, a novel "atypical" antipsychotic agent
-
Moore NA, Tye NC, Axton MS and Risius FC (1992) The behavioral pharmacology of olanzapine, a novel "atypical" antipsychotic agent. J Pharmacol Exp Ther 262: 545-551.
-
(1992)
J Pharmacol Exp Ther
, vol.262
, pp. 545-551
-
-
Moore, N.A.1
Tye, N.C.2
Axton, M.S.3
Risius, F.C.4
-
25
-
-
0014634691
-
The influence of various neuroleptic drugs on shock avoidance responding in rats
-
Niemegeers CJE, Verbruggen FJ and Janssen PAJ (1969) The influence of various neuroleptic drugs on shock avoidance responding in rats. Psychopharmacologia 16:161-174.
-
(1969)
Psychopharmacologia
, vol.16
, pp. 161-174
-
-
Niemegeers, C.J.E.1
Verbruggen, F.J.2
Janssen, P.A.J.3
-
26
-
-
84981878828
-
The inhibition of the conditioned response and the counteraction of schizophrenia by muscarinic stimulation of the brain
-
Pfeiffer CC and Jenny EH (1957) The inhibition of the conditioned response and the counteraction of schizophrenia by muscarinic stimulation of the brain. Ann NY Acad Sci 66:753-764.
-
(1957)
Ann NY Acad Sci
, vol.66
, pp. 753-764
-
-
Pfeiffer, C.C.1
Jenny, E.H.2
-
28
-
-
0028926113
-
Human muscarinic receptors expressed in A9L and CHO cells: Activation by full and partial agonists
-
Richards MH and van Giersbergen PLM (1995) Human muscarinic receptors expressed in A9L and CHO cells: Activation by full and partial agonists. Br J Pharmacol 114:1241-1249.
-
(1995)
Br J Pharmacol
, vol.114
, pp. 1241-1249
-
-
Richards, M.H.1
Van Giersbergen, P.L.M.2
-
29
-
-
15144344046
-
Muscarinic agonists with antipsychotic-like activity: Structure activity relationships of 1,2,5-thiadiazole analogues with functional dopamine antagonist activity
-
Sauerberg P, Jeppesen L, Olesen PH, Rasmussen T, Swedberg MDB, Sheardown MJ, Fink-Jensen A, Thomsen C, Thogersen H, Ward JS, Calligaro DO, DeLapp NW, Bymaster FP and Shannon HE (1998) Muscarinic agonists with antipsychotic-like activity: Structure activity relationships of 1,2,5-thiadiazole analogues with functional dopamine antagonist activity. J Med Chem 41:4378-4384.
-
(1998)
J Med Chem
, vol.41
, pp. 4378-4384
-
-
Sauerberg, P.1
Jeppesen, L.2
Olesen, P.H.3
Rasmussen, T.4
Swedberg, M.D.B.5
Sheardown, M.J.6
Fink-Jensen, A.7
Thomsen, C.8
Thogersen, H.9
Ward, J.S.10
Calligaro, D.O.11
DeLapp, N.W.12
Bymaster, F.P.13
Shannon, H.E.14
-
30
-
-
0026611521
-
1 selective muscarinic agonists: Synthesis and structure-activity relationships of 3-(1,2,5-thiadizolyl)-1,2,5,6-tetrahydro-1-methylpvridines
-
1 selective muscarinic agonists: Synthesis and structure-activity relationships of 3-(1,2,5-thiadizolyl)-1,2,5,6-tetrahydro-1-methylpvridines. J Med Chem 35:2274-2283.
-
(1992)
J Med Chem
, vol.35
, pp. 2274-2283
-
-
Sauerberg, P.1
Olesen, P.H.2
Nielsen, S.3
Treppendahl, S.4
Sheardown, M.J.5
Honore, T.6
Mitch, C.7
Ward, J.8
Pike, A.9
Bymaster, F.P.10
Sawyer, B.11
Shannon, H.E.12
-
31
-
-
0027475913
-
Characterization of muscarinic agonists in recombinant cell lines
-
Schwarz RD, Davis RE, Jaen JC, Spencer CJ, Tecle H and Thomas AJ (1993) Characterization of muscarinic agonists in recombinant cell lines. Life Sci 52:465-472.
-
(1993)
Life Sci
, vol.52
, pp. 465-472
-
-
Schwarz, R.D.1
Davis, R.E.2
Jaen, J.C.3
Spencer, C.J.4
Tecle, H.5
Thomas, A.J.6
-
32
-
-
0028941137
-
Preclinical and phase I clinical characterization of CI979/RU35926, a novel muscarinic agonist for the treatment of Alzheimer's disease
-
Sedman AJ, Bockbrader H and Schwarz RD (1995) Preclinical and phase I clinical characterization of CI979/RU35926, a novel muscarinic agonist for the treatment of Alzheimer's disease. Life Sci 58:877-882.
-
(1995)
Life Sci
, vol.58
, pp. 877-882
-
-
Sedman, A.J.1
Bockbrader, H.2
Schwarz, R.D.3
-
33
-
-
0028344181
-
1 muscarinic receptor agonist
-
1 muscarinic receptor agonist. J Pharmacol Exp Ther 269:271-281.
-
(1994)
J Pharmacol Exp Ther
, vol.269
, pp. 271-281
-
-
Shannon, H.E.1
Bymaster, F.P.2
Calligaro, D.O.3
Greenwood, B.4
Mitch, C.H.5
Sawyer, B.D.6
Ward, J.S.7
Wong, D.T.8
Olesen, P.H.9
Sheardown, M.J.10
Suzdak, P.D.11
Sauerberg, P.12
-
34
-
-
0024321406
-
Cholinergic hyperactivity and negative schizophrenic symptoms
-
Tandon R and Greden JF (1989) Cholinergic hyperactivity and negative schizophrenic symptoms. Arch Gen Psychiatry 46:745-753.
-
(1989)
Arch Gen Psychiatry
, vol.46
, pp. 745-753
-
-
Tandon, R.1
Greden, J.F.2
-
35
-
-
0026025726
-
Muscarinic cholinergic hyperactivity in schizophrenia: Relationship to positive and negative symptoms
-
Tandon R, Shipley JE, Greden JF, Mann NA, Eisner WH and Goodson J (1991) Muscarinic cholinergic hyperactivity in schizophrenia: Relationship to positive and negative symptoms. Schizophr Res 4:23-30.
-
(1991)
Schizophr Res
, vol.4
, pp. 23-30
-
-
Tandon, R.1
Shipley, J.E.2
Greden, J.F.3
Mann, N.A.4
Eisner, W.H.5
Goodson, J.6
-
36
-
-
0344168905
-
Effects of secobarbital and pentobarbital on escape and avoidance behavior
-
Verhave T, Owen JE and Robbins EB (1957) Effects of secobarbital and pentobarbital on escape and avoidance behavior. Psychol Rep 3:421-428.
-
(1957)
Psychol Rep
, vol.3
, pp. 421-428
-
-
Verhave, T.1
Owen, J.E.2
Robbins, E.B.3
-
37
-
-
0029967523
-
Schizophrenia and Alzheimer's disease: Clinical and pathophysiologic analogies
-
White KG and Cummings JL (1996) Schizophrenia and Alzheimer's disease: Clinical and pathophysiologic analogies. Compr Psychiatry 37:188-195.
-
(1996)
Compr Psychiatry
, vol.37
, pp. 188-195
-
-
White, K.G.1
Cummings, J.L.2
-
38
-
-
0028914212
-
Role of tegmental cholinergic neurons in dopaminergic activation, antimuscarinic psychosis and schizophrenia
-
Yeomans JS (1995) Role of tegmental cholinergic neurons in dopaminergic activation, antimuscarinic psychosis and schizophrenia. Neuropharmacology 12:3-16.
-
(1995)
Neuropharmacology
, vol.12
, pp. 3-16
-
-
Yeomans, J.S.1
-
39
-
-
0027716799
-
Rewarding brain stimulation: Role of tegmental cholinergic neurons that activate dopamine neurons
-
Yeomans JS, Mathur A and Tampakeras M (1993) Rewarding brain stimulation: Role of tegmental cholinergic neurons that activate dopamine neurons. Behav Neurosci 107:1077-1087.
-
(1993)
Behav Neurosci
, vol.107
, pp. 1077-1087
-
-
Yeomans, J.S.1
Mathur, A.2
Tampakeras, M.3
|