Gelastatins, new inhibitors of matrix metalloproteinases from Westerdykella multispora F50733

Annals of the New York Academy of Sciences

Volumn 878, Issue , 1999, Pages 635-637

  Lee, Ho Jae ^a   Chung, Myung Chul ^a   Lee, Choong Hwan ^a   Chun, Hyo Kon ^a   Rhee, Joon Shick ^b   Kho, Yung Hee ^a  

^a Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^b Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGENASE; GELASTATIN A; GELASTATIN B; GELATINASE A; GELATINASE B; MATRIX METALLOPROTEINASE INHIBITOR; STROMELYSIN; UNCLASSIFIED DRUG;

CANCER INVASION; CONFERENCE PAPER; DRUG EFFECT; DRUG ISOLATION; DRUG STRUCTURE; FUNGUS;

FUNGI; WESTERDYKELLA;

EID: 0032838953     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1999.tb07748.x     Document Type: Conference Paper

References (7)

1. 1. Woessner, J.F., Jr. 1991. Matrix metalloproteinases and their inhibitors in connective tissue remodeling. FASEB J. 5: 2145-2154.
2. 2. Lee, H.J., M.C. Chung, C.H. Lee, B.S. Yun, H.K. Chun & Y.H. Kho. 1997. Gelastatins A and B, new inhibitors of gelatinase A from Westerdykella multispora F0733. J. Antibiotics 50: 357-359.
3. 3. Knight, C.G., F. Willenbrock & G. Murphy. 1992. A novel coumarin-labelled peptide for sensitive continuous assays of the matrix metalloproteinases. FEBS Lett. 296: 263-266.
4. 4. Saito, K., T. Oku, N. Ata, H. Miyashino, M. Hattori & I. Saiki. 1997. A modified and convenient method for assessing tumor cell invasion and migration and its application to screening for inhibitors. Biol. Pharm. Bull. 20: 345-348.
5. 5. Faucher, D.C., Y. Lelievre & T. Cartwright. 1987. An inhibitor of mammalian collagenase active at micromolar concentrations from an actinomycete culture broth. J. Antibiotics 40: 357-359.
6. 6. Tanzawa, K., M. Ishii, T. Ogita & K. Shimada. 1992. Matlystatins, new inhibitors of type IV collagenases from Actinomadura altramentaria. II. Biological activities. J. Antibiotics 45: 1733-1737.
7. 7. Naito, K., S. Nakajima, N. Kanbayashi, A. Okuyama & M. Goto. 1993. Inhibition of metalloproteinase activity of rheumatoid arthritis synovial cells by a new inhibitor [BE16627B; L-N-(N-hydroxy-2-isobutylsuccinamoyl)-seryl-L-valine]. Agents Actions 389: 182-186.