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T(8;21) breakpoints on chromosome 21 in acute myeloid leukemia are clustered within limited region of a single gene, AML1
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Identification of breakpoints in t(8;21) acute myelogenous leukemia and isolation of a fusion transcript, AML-1/ETO, with similarity to Drosophila segmentation gene, runt
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The 8;21 chromosome translocation in acute myeloid leukemia is always detectable by molecular analysis using AML1
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An AML/ETO fusion transcript is consistently detected by RNA-based polymerase chain reaction in acute myelogenous leukemia containing the t(8;21)(q22;q22) translocation
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Junction of the AML1/MTG8 (ETO) fusion are constant in t(8;21) acute myeloid leukemia detected by reverse transcription polymerase chain reaction
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AML1/ETO fusion mRNA can be detected in remission blood samples of all patients with t(8;21) acute myeloid leukemia after chemotherapy or autologous bone marrow transplantation
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Kusec R., Laczika K., Knobl P., Friedl J., Greinix H., Kahls P., Linkesch W., Schwarzinger I., Mitterbauer G., Purtscher B. AML1/ETO fusion mRNA can be detected in remission blood samples of all patients with t(8;21) acute myeloid leukemia after chemotherapy or autologous bone marrow transplantation. Leukemia. 8:1994;735-739.
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