Membrane-interaction QSAR analysis: Application to the estimation of eye irritation by organic compounds

Pharmaceutical Research

Volumn 16, Issue 8, 1999, Pages 1245-1253

  Kulkarni, Amit S ^a   Hopfinger, A J ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

Genetic function approximation; Molar adjusted eye scores; Molecular dynamics simulations; Partial least squares regression; Quantitative structure activity relationship

Indexed keywords

ACETIC ACID DERIVATIVE; ALCOHOL; AROMATIC COMPOUND; HYDROCARBON; KETONE; ORGANIC COMPOUND;

ARTICLE; ARTIFICIAL MEMBRANE; CELL TRANSPORT; CORNEA CELL; DIFFUSION; ECOTOXICOLOGY; EYE IRRITATION; MEMBRANE BINDING; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION;

ANIMALS; CELL MEMBRANE; COMPUTER SIMULATION; EYE; EYE FOREIGN BODIES; IRRITANTS; MODELS, BIOLOGICAL; RABBITS; SOLUBILITY; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0032837628     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1014853731428     Document Type: Article

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