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Volumn 15, Issue 3, 1999, Pages 197-205

Cyclosporin pharmacokinetics in the elderly

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOSPORIN; CYCLOSPORIN A; CYTOCHROME P450; ERYTHROMYCIN; GLYCOPROTEIN P; NIFEDIPINE; NONSTEROID ANTIINFLAMMATORY AGENT; PREDNISOLONE;

EID: 0032837161     PISSN: 1170229X     EISSN: None     Source Type: Journal    
DOI: 10.2165/00002512-199915030-00003     Document Type: Review
Times cited : (46)

References (38)
  • 1
    • 0027174992 scopus 로고
    • Cyclosporin clinical pharmacokinetics
    • Fahr A. Cyclosporin clinical pharmacokinetics. Clin Pharmacokinet 1993; 24: 472-95
    • (1993) Clin Pharmacokinet , vol.24 , pp. 472-495
    • Fahr, A.1
  • 2
    • 0027412383 scopus 로고
    • International consensus report: The use of cyclosporin A in rheumatoid arthritis
    • Wells G, Tugwell P. International consensus report: the use of cyclosporin A in rheumatoid arthritis. Br J Rheumatol 1993; 32: 1-3
    • (1993) Br J Rheumatol , vol.32 , pp. 1-3
    • Wells, G.1    Tugwell, P.2
  • 3
    • 0027687504 scopus 로고    scopus 로고
    • Rheumatoid arthritis in the aged: Incidence and optimal management
    • Nesher G, Moore TL. Rheumatoid arthritis in the aged: incidence and optimal management. Drugs Aging 1998; 3: 487-501
    • (1998) Drugs Aging , vol.3 , pp. 487-501
    • Nesher, G.1    Moore, T.L.2
  • 4
    • 0029657780 scopus 로고    scopus 로고
    • Shift in the incidence of rheumatoid arthritis toward elderly patients in Finland
    • Kaipiainen-Seppanen O, Abo K, Isomaki H, et al. Shift in the incidence of rheumatoid arthritis toward elderly patients in Finland. Clin Exp Rheumatol 1996; 14: 537-42
    • (1996) Clin Exp Rheumatol , vol.14 , pp. 537-542
    • Kaipiainen-Seppanen, O.1    Abo, K.2    Isomaki, H.3
  • 5
    • 0030982413 scopus 로고    scopus 로고
    • Clinical pharmacokinetic considerations in the elderly
    • Kinirons MT, Crome P. Clinical pharmacokinetic considerations in the elderly. Clin Pharmacokinet 1997; 33: 302-31
    • (1997) Clin Pharmacokinet , vol.33 , pp. 302-331
    • Kinirons, M.T.1    Crome, P.2
  • 6
    • 0024447750 scopus 로고
    • Clinical pharmacokinetics in the elderly: An update
    • Dawling S, Crome P. Clinical pharmacokinetics in the elderly: an update. Clin Pharmacokinet 1989; 17: 236-63
    • (1989) Clin Pharmacokinet , vol.17 , pp. 236-263
    • Dawling, S.1    Crome, P.2
  • 8
    • 0028820208 scopus 로고
    • Differentiation of absorption and first-pass gut and hepatic metabolism in humans: Studies with cyclosporine
    • Wu CY, Benet LZ, Hebert MF, et al. Differentiation of absorption and first-pass gut and hepatic metabolism in humans: studies with cyclosporine. Clin Pharmacol Ther 1995; 58: 492-7
    • (1995) Clin Pharmacol Ther , vol.58 , pp. 492-497
    • Wu, C.Y.1    Benet, L.Z.2    Hebert, M.F.3
  • 9
    • 0025719746 scopus 로고
    • First-pass metabolism of cyclosporin by the gut
    • Kolars JC, Awni WM, Merion RM, et al. First-pass metabolism of cyclosporin by the gut. Lancet 1991; 338: 1488-90
    • (1991) Lancet , vol.338 , pp. 1488-1490
    • Kolars, J.C.1    Awni, W.M.2    Merion, R.M.3
  • 10
    • 0026659150 scopus 로고
    • Cyclosporin metabolism by human gastrointestinal mucosal microsomes
    • Webber IR, Peters WHM, Back DJ. Cyclosporin metabolism by human gastrointestinal mucosal microsomes. Br J Clin Pharmacol 1992; 33: 661-4
    • (1992) Br J Clin Pharmacol , vol.33 , pp. 661-664
    • Webber, I.R.1    Peters, W.H.M.2    Back, D.J.3
  • 11
    • 0025099408 scopus 로고
    • Hepatic drug metabolism and ageing
    • Woodhouse KM, James OFW. Hepatic drug metabolism and ageing. Br Med Bull 1990; 46: 22-35
    • (1990) Br Med Bull , vol.46 , pp. 22-35
    • Woodhouse, K.M.1    James, O.F.W.2
  • 12
    • 0026708362 scopus 로고
    • Effect of age and gender on the activity of human hepatic CYP3A
    • Hunt CM, Westerkam WR, Stave GM. Effect of age and gender on the activity of human hepatic CYP3A. Biochem Pharmacol 1992; 44: 275-83
    • (1992) Biochem Pharmacol , vol.44 , pp. 275-283
    • Hunt, C.M.1    Westerkam, W.R.2    Stave, G.M.3
  • 13
    • 0025102277 scopus 로고
    • Effect of age on single and multiple dose pharmacokinetics of crythromycin
    • Miglioli PA, Pivetta P, Strazzabosco M, et al. Effect of age on single and multiple dose pharmacokinetics of crythromycin. Eur J Clin Pharmacol 1990; 39: 164-4
    • (1990) Eur J Clin Pharmacol , vol.39 , pp. 164-174
    • Miglioli, P.A.1    Pivetta, P.2    Strazzabosco, M.3
  • 14
    • 0023918735 scopus 로고
    • Age related changes in the pharmacokinetics and pharmacodynamics of nifedipine
    • Robertson DRC, Waller DG, Renwick AG, et al. Age related changes in the pharmacokinetics and pharmacodynamics of nifedipine. Br J Clin Pharmacol 1988; 25: 297-305
    • (1988) Br J Clin Pharmacol , vol.25 , pp. 297-305
    • Robertson, D.R.C.1    Waller, D.G.2    Renwick, A.G.3
  • 15
    • 0023447098 scopus 로고
    • Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues
    • Thiebaut F, Tsuruo T, Harmada H, et al. Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues. Proc Natl Acad Sci U S A 1987; 84; 7735-8
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 7735-7738
    • Thiebaut, F.1    Tsuruo, T.2    Harmada, H.3
  • 16
    • 0027418815 scopus 로고
    • Human P-glycoprotein transports cyclosporin A and FK506
    • Sacki T, Ueda K, Tanigawara Y, et al. Human P-glycoprotein transports cyclosporin A and FK506. J Biol Chem 1993; 268: 6077-80
    • (1993) J Biol Chem , vol.268 , pp. 6077-6080
    • Sacki, T.1    Ueda, K.2    Tanigawara, Y.3
  • 17
    • 12644272784 scopus 로고    scopus 로고
    • Role of intestinal P-glycoprotein (mdrl) in interpatient variation in the oral bioavailability of cyclosporine
    • Lown KS, Mayo RR, Leichtman AB, et al. Role of intestinal P-glycoprotein (mdrl) in interpatient variation in the oral bioavailability of cyclosporine. Clin Pharmacol Ther 1997; 62: 248-60
    • (1997) Clin Pharmacol Ther , vol.62 , pp. 248-260
    • Lown, K.S.1    Mayo, R.R.2    Leichtman, A.B.3
  • 18
    • 0029337445 scopus 로고
    • P-glycoprotein expression and regulation: Age-related changes and potential effects on drug therapy
    • Gupta S. P-glycoprotein expression and regulation: age-related changes and potential effects on drug therapy. Drugs Aging 1995; 7: 420-37
    • (1995) Drugs Aging , vol.7 , pp. 420-437
    • Gupta, S.1
  • 19
    • 0025159345 scopus 로고
    • Adverse drug reactions
    • Denham MJ. Adverse drug reactions. Br Med Bull 1990; 46: 53-62
    • (1990) Br Med Bull , vol.46 , pp. 53-62
    • Denham, M.J.1
  • 20
    • 0025941931 scopus 로고
    • Management of drug interactions with cyclosporine
    • Lake KD. Management of drug interactions with cyclosporine. Pharmacotherapy 1991; 11: 110S-8
    • (1991) Pharmacotherapy , vol.11
    • Lake, K.D.1
  • 21
    • 0031836446 scopus 로고    scopus 로고
    • Polypharmacy: Correlations with sex, age and drug regimen
    • Bjerrum L, Sogarrd J, Hallas J, et al. Polypharmacy: correlations with sex, age and drug regimen. Eur J Clin Pharmacol 1998; 54: 197-202
    • (1998) Eur J Clin Pharmacol , vol.54 , pp. 197-202
    • Bjerrum, L.1    Sogarrd, J.2    Hallas, J.3
  • 22
    • 0029960192 scopus 로고    scopus 로고
    • Drug interactions and interindividual variability of ciclosporin metabolism in the small intestine
    • Lampen A, Christians L, Bader A, et al. Drug interactions and interindividual variability of ciclosporin metabolism in the small intestine. Pharmacology 1996; 52: 159-68
    • (1996) Pharmacology , vol.52 , pp. 159-168
    • Lampen, A.1    Christians, L.2    Bader, A.3
  • 23
    • 0025134337 scopus 로고
    • Cyclosporin A drug interactions: Screening for inducers and inhibitors of cytochrome P-450 (cyclosporin A oxidase) in primary cultures of human hepatocytes and in liver microsomes
    • Pichard L., Fabre I, Fabre G. et al. Cyclosporin A drug interactions: screening for inducers and inhibitors of cytochrome P-450 (cyclosporin A oxidase) in primary cultures of human hepatocytes and in liver microsomes. Drug Metab Dispos 1990; 18: 595-606
    • (1990) Drug Metab Dispos , vol.18 , pp. 595-606
    • Pichard, L.1    Fabre, I.2    Fabre, G.3
  • 24
    • 0023818445 scopus 로고
    • Specific 3H radioimmunoassay with a monoclonal antibody for monitoring cyclosporine in blood
    • Ball PE, Munzer H, Keller HP, et al. Specific 3H radioimmunoassay with a monoclonal antibody for monitoring cyclosporine in blood. Clin Chem 1988; 34: 257-60
    • (1988) Clin Chem , vol.34 , pp. 257-260
    • Ball, P.E.1    Munzer, H.2    Keller, H.P.3
  • 25
    • 0023694383 scopus 로고
    • On the dose dependency of cyclosporin A absorption and disposition in healthy volunteers
    • Revmond JP, Steimer JL, Nicderberger W. On the dose dependency of cyclosporin A absorption and disposition in healthy volunteers. J Pharmacokinet Biopharm 1989; 16: 331-53
    • (1989) J Pharmacokinet Biopharm , vol.16 , pp. 331-353
    • Revmond, J.P.1    Steimer, J.L.2    Nicderberger, W.3
  • 26
    • 0009708617 scopus 로고
    • Rockville (MD): Food and Drug Administration Center for Drug Evaluation
    • Food and Drug Administration Center for Drug Evaluation. Guidance: statistical procedures for bioequivalence studies. Rockville (MD): Food and Drug Administration Center for Drug Evaluation, 1992
    • (1992) Guidance: Statistical Procedures for Bioequivalence Studies
  • 27
    • 0023615056 scopus 로고
    • A comparison of the two one-sided procedure and the power approach for assessing the equivalence of average bioavailability
    • Schuirmann DJ. A comparison of the two one-sided procedure and the power approach for assessing the equivalence of average bioavailability. J Pharmacokinet Biopharm 1987; 15: 657-80
    • (1987) J Pharmacokinet Biopharm , vol.15 , pp. 657-680
    • Schuirmann, D.J.1
  • 28
    • 0022651554 scopus 로고
    • Demographic factors affecting the pharmacokinetics of cyclosporine estimated by radioimmunoassay
    • Kahan BD, Kramer WG, Wideman C. Demographic factors affecting the pharmacokinetics of cyclosporine estimated by radioimmunoassay. Transplantation 1986; 41: 459-67
    • (1986) Transplantation , vol.41 , pp. 459-467
    • Kahan, B.D.1    Kramer, W.G.2    Wideman, C.3
  • 29
    • 0031706572 scopus 로고    scopus 로고
    • Population pharmacokinetics of cyclosporine: Influence of covariables and assessment of cyclosporine absorption in kidney, lung, heart, and heart-lung transplanted patients
    • Kyhl I.F.B, Rasmussen SN, Aaron L, et al. Population pharmacokinetics of cyclosporine: influence of covariables and assessment of cyclosporine absorption in kidney, lung, heart, and heart-lung transplanted patients [abstract]. Transplant Proc 1998; 30: 1680
    • (1998) Transplant Proc , vol.30 , pp. 1680
    • Kyhl, I.F.B.1    Rasmussen, S.N.2    Aaron, L.3
  • 30
    • 0002212672 scopus 로고
    • Effects of dose and treatment duration on adverse experience with cyclosporine in RA: Analysis of North American trials
    • Torley H, Yocum D. Effects of dose and treatment duration on adverse experience with cyclosporine in RA: analysis of North American trials [abstract]. Arthritis Rheum 1994; 37: Suppl.: 334
    • (1994) Arthritis Rheum , vol.37 , Issue.SUPPL. , pp. 334
    • Torley, H.1    Yocum, D.2
  • 31
    • 0029448134 scopus 로고
    • Disease-modifying antirheumatic drugs: Potential effects in older patients
    • Gardner G, Furst DE. Disease-modifying antirheumatic drugs: potential effects in older patients. Drugs Aging 1995; 7:420-37
    • (1995) Drugs Aging , vol.7 , pp. 420-437
    • Gardner, G.1    Furst, D.E.2
  • 32
    • 0030345177 scopus 로고    scopus 로고
    • Transplantation in the elderly: Changing philosophy
    • Santiago-Delphin EA. Transplantation in the elderly: changing philosophy. Transplant Proc 1996; 28: 3408-9
    • (1996) Transplant Proc , vol.28 , pp. 3408-3409
    • Santiago-Delphin, E.A.1
  • 34
    • 0028158355 scopus 로고
    • Cadaveric renal transplantation after 60 years of age: A single center experience
    • Cantarovich D, Baatard R, Baranger T, et al. Cadaveric renal transplantation after 60 years of age: a single center experience. Transplant Int 1994; 7: 33-8
    • (1994) Transplant Int , vol.7 , pp. 33-38
    • Cantarovich, D.1    Baatard, R.2    Baranger, T.3
  • 35
    • 0024535786 scopus 로고
    • Cadaveric renal transplantation with cyclosporine in patients more than 60 years of age
    • Pirsch JD, Stratta RJ, Armbrust MJ, et al. Cadaveric renal transplantation with cyclosporine in patients more than 60 years of age. Transplantation 1989; 47: 259-61
    • (1989) Transplantation , vol.47 , pp. 259-261
    • Pirsch, J.D.1    Stratta, R.J.2    Armbrust, M.J.3
  • 36
    • 0026843015 scopus 로고
    • Renal transplantation in patients 65 years old or older
    • Vivas CA, Hickey DP, Jordan ML, et al. Renal transplantation in patients 65 years old or older. J Urol 1992; 147: 990-3
    • (1992) J Urol , vol.147 , pp. 990-993
    • Vivas, C.A.1    Hickey, D.P.2    Jordan, M.L.3
  • 37
    • 0030323708 scopus 로고    scopus 로고
    • Long-term results of solid organ transplantation: Report from the Eurotransplant International Foundation
    • Smits JM, DeMeester J, Persijn GG, et al. Long-term results of solid organ transplantation: report from the Eurotransplant International Foundation. Clin Transplant 1996; 10: 109-27
    • (1996) Clin Transplant , vol.10 , pp. 109-127
    • Smits, J.M.1    Demeester, J.2    Persijn, G.G.3
  • 38
    • 0032980695 scopus 로고    scopus 로고
    • Conversion of patients with rheumatoid arthritis from the conventional to a microemulsion formulation of cyclosporin: A double blind comparison to screen for differences in safety, efficacy, and pharmacokinetics
    • Anderson IF, Helve T, Hannonen P, et al. Conversion of patients with rheumatoid arthritis from the conventional to a microemulsion formulation of cyclosporin: a double blind comparison to screen for differences in safety, efficacy, and pharmacokinetics. J Rheumatol 1999; 26; 556-62
    • (1999) J Rheumatol , vol.26 , pp. 556-562
    • Anderson, I.F.1    Helve, T.2    Hannonen, P.3


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