메뉴 건너뛰기




Volumn 6, Issue 8, 1999, Pages 736-744

Benzamide riboside induces apoptosis independent of Cdc25A expression in human ovarian carcinoma N.1 cells

Author keywords

Apoptosis; Benzamide riboside; c myc induction; Cdc25A repression; Cyclin D1 prad 1 expression; IMP dehydrogenase inhibitor

Indexed keywords

BENZAMIDE; CELL CYCLE PROTEIN; DNA FRAGMENT; INOSINATE DEHYDROGENASE; MESSENGER RNA;

EID: 0032836084     PISSN: 13509047     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cdd.4400546     Document Type: Article
Times cited : (27)

References (50)
  • 1
    • 0016823448 scopus 로고
    • IMP dehydrogenase: An enzyme linked with proliferation and malignancy
    • Jackson RC, Weber G and Morris HP (1975) IMP dehydrogenase: an enzyme linked with proliferation and malignancy. Nature 256: 331-333
    • (1975) Nature , vol.256 , pp. 331-333
    • Jackson, R.C.1    Weber, G.2    Morris, H.P.3
  • 2
    • 0020955571 scopus 로고
    • Biochemical strategy of cancer cells and design of chemotherapy
    • G.H.A. Clowes Memorial Lecture
    • Weber G (1983) Biochemical strategy of cancer cells and design of chemotherapy, G.H.A. Clowes Memorial Lecture. Cancer Res. 43: 3466-3492
    • (1983) Cancer Res. , vol.43 , pp. 3466-3492
    • Weber, G.1
  • 3
    • 0027245461 scopus 로고
    • Biochemical consequences of resistance to tiazofurin in human myelogenous leukemic K562 cells
    • Jayaram HN, Zhen W and Gharehbaghi K (1993) Biochemical consequences of resistance to tiazofurin in human myelogenous leukemic K562 cells. Cancer Res. 53: 2344-2348
    • (1993) Cancer Res. , vol.53 , pp. 2344-2348
    • Jayaram, H.N.1    Zhen, W.2    Gharehbaghi, K.3
  • 5
    • 0019948293 scopus 로고
    • Initial studies on the mechanism of action of a new oncolytic thiazole nucleoside, 2-β-D-ribofuranosylthiazole-4-carboxamide (NSC 286193)
    • Jayaram HN, Dion RL, Glazer RI, Johns DG, Robins RK, Srivastava PC and Cooney DA (1982) Initial studies on the mechanism of action of a new oncolytic thiazole nucleoside, 2-β-D-ribofuranosylthiazole-4-carboxamide (NSC 286193). Biochem. Pharmacol. 31: 2371-2380
    • (1982) Biochem. Pharmacol. , vol.31 , pp. 2371-2380
    • Jayaram, H.N.1    Dion, R.L.2    Glazer, R.I.3    Johns, D.G.4    Robins, R.K.5    Srivastava, P.C.6    Cooney, D.A.7
  • 8
    • 0030499841 scopus 로고    scopus 로고
    • Tiazofurin effects on IMP-dehydrogenase activity and expression in the leukemia cells of patients with CML blast crisis
    • Wright DG, Boosalis MS, Waraska K, Oshry LJ, Weeintraub LR andVosburgh E (1996) Tiazofurin effects on IMP-dehydrogenase activity and expression in the leukemia cells of patients with CML blast crisis. Anticancer Res. 16: 3349-3354
    • (1996) Anticancer Res. , vol.16 , pp. 3349-3354
    • Wright, D.G.1    Boosalis, M.S.2    Waraska, K.3    Oshry, L.J.4    Weeintraub, L.R.5    Vosburgh, E.6
  • 9
    • 0026605818 scopus 로고
    • Synthesis and cytotoxic activity of C-glycosidic nicotinamide riboside analogues
    • Krohn K, Heins H and Wielckens K (1992) Synthesis and cytotoxic activity of C-glycosidic nicotinamide riboside analogues. J. Med. Chem. 35: 511-517
    • (1992) J. Med. Chem. , vol.35 , pp. 511-517
    • Krohn, K.1    Heins, H.2    Wielckens, K.3
  • 11
    • 0028105124 scopus 로고
    • Comparison of biochemical parameters of benzamide riboside, a new inhibitor of IMP dehydrogenase, with tiazofurin and selenazofurin
    • Gharehbaghi K, Sreenath A, Hao Z, Paull KD, Szekeres T, Cooney DA, Krohn K and Jayaram HN (1994) Comparison of biochemical parameters of benzamide riboside, a new inhibitor of IMP dehydrogenase, with tiazofurin and selenazofurin. Biochem. Pharmacol. 48: 1413-1419
    • (1994) Biochem. Pharmacol. , vol.48 , pp. 1413-1419
    • Gharehbaghi, K.1    Sreenath, A.2    Hao, Z.3    Paull, K.D.4    Szekeres, T.5    Cooney, D.A.6    Krohn, K.7    Jayaram, H.N.8
  • 13
    • 0019953349 scopus 로고
    • The conversion of 2-β-D-ribofuranosylthiazole-4-carboxamide to an analog of NAD with potent IMP dehydrogenase-inhibitory properties
    • Cooney DA, Jayaram HN, Gebeyehu G, Betts CR, Kelley JA, Marquez VE and Johns DG (1982) The conversion of 2-β-D-ribofuranosylthiazole-4-carboxamide to an analog of NAD with potent IMP dehydrogenase-inhibitory properties. Biochem. Pharmacol. 31: 2133-2136
    • (1982) Biochem. Pharmacol. , vol.31 , pp. 2133-2136
    • Cooney, D.A.1    Jayaram, H.N.2    Gebeyehu, G.3    Betts, C.R.4    Kelley, J.A.5    Marquez, V.E.6    Johns, D.G.7
  • 14
    • 0025853338 scopus 로고
    • Separation of clonogenic and differentiated cell phenotypes of ovarian cancer cells HOC-7 by discontinuous density gradient centrifugation
    • Grunt T, Dittrich E, Somay C, Wagner T and Dittrich C (1991) Separation of clonogenic and differentiated cell phenotypes of ovarian cancer cells HOC-7 by discontinuous density gradient centrifugation. Cancer Lett. 58: 7-16
    • (1991) Cancer Lett. , vol.58 , pp. 7-16
    • Grunt, T.1    Dittrich, E.2    Somay, C.3    Wagner, T.4    Dittrich, C.5
  • 16
    • 0029002337 scopus 로고
    • Sodium butyrate inhibits c-myc splicing and interferes with signal transduction in ovarian carcinoma cells
    • Krupitza G, Harant H, Dittrich E, Szekeres T, Huber H and Dittrich C (1995) Sodium butyrate inhibits c-myc splicing and interferes with signal transduction in ovarian carcinoma cells. Carcinogenesis 16: 1199-1205
    • (1995) Carcinogenesis , vol.16 , pp. 1199-1205
    • Krupitza, G.1    Harant, H.2    Dittrich, E.3    Szekeres, T.4    Huber, H.5    Dittrich, C.6
  • 17
    • 0027517636 scopus 로고
    • Differential kinetics of propidium iodide uptake in apoptotic and necrotic thymocytes
    • Vitale M, Zamai L, Mazzotti G, Cataldi A and Falcieri E (1993) Differential kinetics of propidium iodide uptake in apoptotic and necrotic thymocytes. Histochemistry 100: 223-229
    • (1993) Histochemistry , vol.100 , pp. 223-229
    • Vitale, M.1    Zamai, L.2    Mazzotti, G.3    Cataldi, A.4    Falcieri, E.5
  • 18
    • 0028793257 scopus 로고
    • Glutamate-induced neuronal cell death: A succession of necrosis or apoptosis depending on mitochondrial function
    • Ankarcrona M, Dypbukt JM, Bonfoco E, Zhivotovsky B, Orrenius S, Lipton SA and Nicotera P (1995) Glutamate-induced neuronal cell death: a succession of necrosis or apoptosis depending on mitochondrial function. Neuron 15: 961-973
    • (1995) Neuron , vol.15 , pp. 961-973
    • Ankarcrona, M.1    Dypbukt, J.M.2    Bonfoco, E.3    Zhivotovsky, B.4    Orrenius, S.5    Lipton, S.A.6    Nicotera, P.7
  • 19
    • 0343267405 scopus 로고    scopus 로고
    • Energy supply and the shape of death in neurons and lymphoid cells
    • Niocotera P and Leist M (1997) Energy supply and the shape of death in neurons and lymphoid cells. Cell Death Differ. 4: 435-442
    • (1997) Cell Death Differ. , vol.4 , pp. 435-442
    • Niocotera, P.1    Leist, M.2
  • 21
    • 0031685216 scopus 로고    scopus 로고
    • Autocrine self elimination of cultured ovarian cancer cells by TNFa
    • Simonitsch I and Krupitza G (1998) Autocrine self elimination of cultured ovarian cancer cells by TNFa. Br. J. Cancer 78: 862-870
    • (1998) Br. J. Cancer , vol.78 , pp. 862-870
    • Simonitsch, I.1    Krupitza, G.2
  • 24
    • 0029779280 scopus 로고    scopus 로고
    • Cdc25 cell-cycle phosphatase as a target of c-myc
    • Galakationov K, Chen X and Beach D (1996) Cdc25 cell-cycle phosphatase as a target of c-myc. Nature 382: 511-517
    • (1996) Nature , vol.382 , pp. 511-517
    • Galakationov, K.1    Chen, X.2    Beach, D.3
  • 26
    • 0028880855 scopus 로고
    • Cyclins, cyclin dependent kinases and cdk inhibitors: Implications in the cell cycle control and cancer
    • MacLachlan TK, Sang N and Giordano A (1995) Cyclins, cyclin dependent kinases and cdk inhibitors: implications in the cell cycle control and cancer. Crit. Rev. Eukaryot. Gene Express 5: 127-156
    • (1995) Crit. Rev. Eukaryot. Gene Express , vol.5 , pp. 127-156
    • MacLachlan, T.K.1    Sang, N.2    Giordano, A.3
  • 27
    • 0025937489 scopus 로고
    • Constitutive c-myc expression in an IL-3 dependent myeloid cell line suppresses cell cycle arrest and accelerates apoptosis
    • Askew DS, Ashmun RC, Simmons BC and Cleveland JL (1991) Constitutive c-myc expression in an IL-3 dependent myeloid cell line suppresses cell cycle arrest and accelerates apoptosis. Oncogene 6: 1915-1922
    • (1991) Oncogene , vol.6 , pp. 1915-1922
    • Askew, D.S.1    Ashmun, R.C.2    Simmons, B.C.3    Cleveland, J.L.4
  • 29
    • 0027985119 scopus 로고
    • C Myc induces cellular susceptibility to the cytotoxic action of TNF-alpha
    • Klefstrom J, Vastrik I, Saksela E, Valle J, Eilers M and Alitalo K (1994) C Myc induces cellular susceptibility to the cytotoxic action of TNF-alpha. EMBO J. 13: 5442-5450
    • (1994) EMBO J. , vol.13 , pp. 5442-5450
    • Klefstrom, J.1    Vastrik, I.2    Saksela, E.3    Valle, J.4    Eilers, M.5    Alitalo, K.6
  • 30
    • 0029822745 scopus 로고
    • Growth arrest by the cyclin dependent kinase inhibitor p27 kip1 is abrogated by c-myc
    • Vlach J, Hennecke S, Alevizopoulos K, Conti D and Amati B (1936) Growth arrest by the cyclin dependent kinase inhibitor p27 kip1 is abrogated by c-myc. EMBO J. 15: 6595-6604
    • (1936) EMBO J. , vol.15 , pp. 6595-6604
    • Vlach, J.1    Hennecke, S.2    Alevizopoulos, K.3    Conti, D.4    Amati, B.5
  • 31
    • 0030909148 scopus 로고    scopus 로고
    • Myc activation of cyclin E/Cdk-2 kinase involves induction of cyclin E gene transcription and inhibition of p27 Kip1 binding to newly formed complexes
    • Perez-Roger I, Solomon D, Sewing A and Land H (1997) Myc activation of cyclin E/Cdk-2 kinase involves induction of cyclin E gene transcription and inhibition of p27 Kip1 binding to newly formed complexes. Oncogene 14: 2373-2381
    • (1997) Oncogene , vol.14 , pp. 2373-2381
    • Perez-Roger, I.1    Solomon, D.2    Sewing, A.3    Land, H.4
  • 32
    • 0030765763 scopus 로고    scopus 로고
    • Activation of c-Myc uncouples DNA-replication from activation of G1-cyclin dependent kinases
    • Pusch O, Bernaschek G, Eilers M and Hengstschläger M (1997) Activation of c-Myc uncouples DNA-replication from activation of G1-cyclin dependent kinases. Oncogene 15: 649-656
    • (1997) Oncogene , vol.15 , pp. 649-656
    • Pusch, O.1    Bernaschek, G.2    Eilers, M.3    Hengstschläger, M.4
  • 33
    • 0029042689 scopus 로고
    • Raf interaction with Cdc25A phosphatase ties mitogenic signal transduction to cell cycle activation
    • Galaktionov K, Jessus C and Beach D (1995) Raf interaction with Cdc25A phosphatase ties mitogenic signal transduction to cell cycle activation. Genes Dev. 9: 1046-1058
    • (1995) Genes Dev. , vol.9 , pp. 1046-1058
    • Galaktionov, K.1    Jessus, C.2    Beach, D.3
  • 36
    • 0030863160 scopus 로고    scopus 로고
    • Paf/MAPK and rapamycin-sensitive pathways mediated the anti-apoptotic function of p21Ras in IL-3 dependent hematopoietic cells
    • Kinoshita T, Shirouzu M, Kamyia A, Hashimoto K, Yokoyama S and Myijima A (1997) Paf/MAPK and rapamycin-sensitive pathways mediated the anti-apoptotic function of p21Ras in IL-3 dependent hematopoietic cells. Oncogene 7: 619-627
    • (1997) Oncogene , vol.7 , pp. 619-627
    • Kinoshita, T.1    Shirouzu, M.2    Kamyia, A.3    Hashimoto, K.4    Yokoyama, S.5    Myijima, A.6
  • 37
    • 0028958705 scopus 로고
    • Growth factor modulation of p53-mediated growth arrest versus apoptosis
    • Canman C, Gilmer T, Coutts S and Kastan M (1995) Growth factor modulation of p53-mediated growth arrest versus apoptosis. Genes Dev. 9: 600-611
    • (1995) Genes Dev. , vol.9 , pp. 600-611
    • Canman, C.1    Gilmer, T.2    Coutts, S.3    Kastan, M.4
  • 39
    • 0028107345 scopus 로고
    • Signal transduction pathways involving the raf proto-oncogene
    • Williams N and Roberts T (1994) Signal transduction pathways involving the raf proto-oncogene. Cancer Metastasis Rev. 13:105-116
    • (1994) Cancer Metastasis Rev. , vol.13 , pp. 105-116
    • Williams, N.1    Roberts, T.2
  • 41
    • 0029094329 scopus 로고
    • Identification of a Myc-dependent step during the formation of active G1 cyclin-cdk complexes
    • Steiner P, Phillip A, Godden-Kent D, Pagano M, Mittnacht S, Bartek J and Eilers M (1995) Identification of a Myc-dependent step during the formation of active G1 cyclin-cdk complexes. EMBO J. 14: 4814-4826
    • (1995) EMBO J. , vol.14 , pp. 4814-4826
    • Steiner, P.1    Phillip, A.2    Godden-Kent, D.3    Pagano, M.4    Mittnacht, S.5    Bartek, J.6    Eilers, M.7
  • 42
    • 0029929124 scopus 로고    scopus 로고
    • Induction of c-myc mediated apoptosis in SV40-transformed rat fibroblasts
    • Lenahan M and Ozer H (1996) Induction of c-myc mediated apoptosis in SV40-transformed rat fibroblasts. Oncogene 12: 1847-1854
    • (1996) Oncogene , vol.12 , pp. 1847-1854
    • Lenahan, M.1    Ozer, H.2
  • 44
    • 0029990598 scopus 로고    scopus 로고
    • S-phase induction by adenovirus E1A requires activation of cdc25A tyrosine phosphatase
    • Spitovsky D, Jansen-Durr P, Karsenti E and Hoffman I (1996) S-phase induction by adenovirus E1A requires activation of cdc25A tyrosine phosphatase. Oncogene 12: 2549-2554
    • (1996) Oncogene , vol.12 , pp. 2549-2554
    • Spitovsky, D.1    Jansen-Durr, P.2    Karsenti, E.3    Hoffman, I.4
  • 46
    • 0023765743 scopus 로고
    • Genes specifically expressed at growth arrest of mammalian cells
    • Schneider C, King L and Philipson L (1988) Genes specifically expressed at growth arrest of mammalian cells. Cell 54: 787-793
    • (1988) Cell , vol.54 , pp. 787-793
    • Schneider, C.1    King, L.2    Philipson, L.3
  • 49
    • 0029026610 scopus 로고
    • Macrophage colony-stimulating factor is expressed by an ovarian carcinoma subline and stimulates the c-myc proto-oncogene
    • Krupitza G, Fritsche R, Dittrich E, Harant H, Huber H, Grunt T and Dittrich C (1995) Macrophage colony-stimulating factor is expressed by an ovarian carcinoma subline and stimulates the c-myc proto-oncogene. Br. J. Cancer 72: 35-40
    • (1995) Br. J. Cancer , vol.72 , pp. 35-40
    • Krupitza, G.1    Fritsche, R.2    Dittrich, E.3    Harant, H.4    Huber, H.5    Grunt, T.6    Dittrich, C.7
  • 50
    • 0030988293 scopus 로고    scopus 로고
    • Deregulated expression of E2F-1 induces cyclin A- and E-associated kinase activities independently from cell cycle position
    • SoucekT, Pusch O, Hengstschläger-Ottnad E, Adams P and Hengstschläger M (1997) Deregulated expression of E2F-1 induces cyclin A- and E-associated kinase activities independently from cell cycle position. Oncogene 14: 2251-2257
    • (1997) Oncogene , vol.14 , pp. 2251-2257
    • Soucek, T.1    Pusch, O.2    Hengstschläger-Ottnad, E.3    Adams, P.4    Hengstschläger, M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.