Morphology of single olivocerebellar axons labeled with biotinylated dextran amine in the rat

Journal of Comparative Neurology

Volumn 414, Issue 2, 1999, Pages 131-148

  Sugihara, I ^a   Wu, H S ^a   Shinoda, Y ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

Afferent pathways; Cerebellar cortex; Cerebellar nuclei; Medulla oblongata; Nerve endings; Purkinje cells

Indexed keywords

AMINE; DEXTRAN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CEREBELLUM; CEREBELLUM NUCLEUS; CLIMBING FIBER; FEMALE; GOLGI COMPLEX; INFERIOR OLIVE; MALE; MEDULLA OBLONGATA; NERVE ENDING; NEUROANATOMY; NONHUMAN; PRIORITY JOURNAL; PURKINJE CELL; RAT; SENSORY NERVE; WHITE MATTER;

ANIMALS; AXONS; BIOTIN; CELL SIZE; CEREBELLAR NUCLEI; DEXTRANS; FEMALE; FLUORESCENT DYES; FUNCTIONAL LATERALITY; MALE; MEDULLA OBLONGATA; NERVE ENDINGS; NEURAL PATHWAYS; OLIVARY NUCLEUS; PURKINJE CELLS; RATS; RATS, LONG-EVANS;

EID: 0032835830     PISSN: 00219967     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9861(19991115)414:2<131::AID-CNE1>3.0.CO;2-F     Document Type: Article

References (61)

1. Altman J, Bayer SA. 1997. Development of the cerebellar system in relation to its evolution, structure, and functions. Boca Raton: CRC Press.
2. Angaut P, Alvarado-Mallart RM, Sotelo C. 1985. Compensatory climbing fiber innervation after unilateral pedunculotomy in the newborn rat: origin and topographic organization. J Comp Neurol 236:161-178.
3. Armstrong DM, Harvey RJ, Schild RF. 1973. The spatial organization of climbing fibre branching in the cat cerebellum. Exp Brain Res 18:40-58.
4. Azizi SA, Woodward DJ. 1987. Inferior olivary nuclear complex of the rat: morphology and comments on the principles of organization within the olivocerebellar system. J Comp Neurol 263:467-484.
5. Brodal A, Walberg F, Berkley KJ, Pelt A. 1980. Anatomical demonstration of branching olivocerebellar fibres by means of a double retrograde labelling technique. Neuroscience 5:2193-2202.
6. Brown PA. 1980. The inferior olivary connections to the cerebellum in the rat studied by retrograde axonal transport of horseradish peroxidase. Brain Res Bull 5:267-275.
7. Buisseret-Delmas C, Angaut P. 1993. The cerebellar olivo-corticonuclear connections in the rat. Prog Neurobiol 40:63-87.
8. Chan-Palay V, Palay SL. 1971. Tendril and glomerular collaterals of climbing fibers in the granular layer of the rat's cerebellar cortex. Z Anat Entwicklungsgesch 133:247-273.
9. 35S-methionine. Exp Brain Res 30:561-576.
10. Crepel F, Mariani J, Delhaye-Bouchaud N. 1976. Evidence for a multiple innervation of Purkinje cells by climbing fibers in the immature rat cerebellum. J Neurobiol 7:567-578.
11. Desclin JC. 1974. Histological evidence supporting the inferior olive as the major source of cerebellar climbing fibers in the rat. Brain Res 77:365-384.
12. de Zeeuw CI, Lang EJ, Sugihara I, Ruigrok TJH, Eisenman LM, Mugnaini E, Llinás R. 1996. Morphological correlates of bilateral synchrony in the rat cerebellar cortex. J Neurosci 16:3412-3426.
13. Eccles JC, Llinás R, Sasaki K. 1966a. The excitatory synaptic action of climbing fibres on the Purkinje cells of the cerebellum. J Physiol [Lond] 182:268-296.
14. Eccles JC, Llinás R, Sasaki K. 1966b. The inhibitory interneurones within the cerebellar cortex. Exp Brain Res 1:1-16.
15. Ekerot C-F, Larson B. 1982. Branching of olivary axons to innervate pairs of sagittal zones in the cerebellar anterior lobe of the cat. Exp Brain Res 48:185-198.
16. Faber DS, Murphy JT, 1969. Axonal branching in the climbing fiber pathway to the cerebellum. Brain Res 15:262-267.
17. Fox CA, Andrade A, Schwyn RC. 1969. Climbing fiber branching in the granular layer. In: Llinás R, editor. Neurobiology of cerebellar evolution and development. Chicago: American Medical Association. p 603-611.
18. Futami T, Shinoda Y, Yokota J. 1979. Spinal axon collaterals of corticospinal neurons identified by intracellular injection of horseradish peroxidase. Brain Res 164:279-284.
19. Groenewegen HJ, Voogd J. 1977. The parasagittal zonation within the olivocerebellar projection. I. Climbing fiber distribution in the vermis of cat cerebellum. J Comp Neurol 174:417-488.
20. Hámori J, Szentágothai J. 1966. Identification under the electron microscope of climbing fibers and their synaptic contacts. Exp Brain Res 1:65-81.
21. Hámori J, Szentágothai J. 1980. Lack of evidence of synaptic contacts by climbing fibre collaterals to basket and stellate cells in developing rat cerebellar cortex. Brain Res 186:454-457.
22. Hrycyshyn AW, Ghazi H, Flumerfelt BA. 1989. Axonal branching of the olivocerebellar projection in the rat: a double-labeling study. J Comp Neurol 284:48-59.
23. Ito M. 1984. The cerebellum and neural control. New York: Raven Press.
24. Itoh K, Konishi A, Nomura S, Mizuno N, Nakamura Y, Sugimoto T. 1979. Application of coupled oxidation reaction to electron microscopic demonstration of horseradish peroxidase: cobalt-glucose oxidase method. Brain Res 175:341-346.
25. Kakei S, Shinoda Y. 1990. Parietal projection of thalamocortical fibers from the ventroanterior-ventrolateral complex of the cat thalamus. Neurosci Lett 117:280-284.
26. Kitai ST, McCrea RA, Preston RJ, Bishop GA. 1977. Electrophysiological and horseradish peroxidase studies of precerebellar afferents to the nucleus interpositus anterior. I. Climbing fiber system. Brain Res 122:197-214.
27. Krieger C, Shinoda Y, Smith AM. 1985. Labelling of cerebellar mossy fiber afferents with intra-axonal horseradish peroxidase. Exp Brain Res 59:414-417.
28. Lang EJ, Sugihara I, Llinás R. 1996. GABAergic modulation of complex spike activity by the cerebellar nucleoolivary pathway in rat. J Neurophysiol 76:255-275.
29. Larsell O. 1952. The morphogenesis and adult pattern of the lobules and fissures of the cerebellum of the white rat. J Comp Neurol 97:281-356.
30. Llinás RR, Walton KD. 1998. Cerebellum. In: Shepherd GM, editor. The synaptic organization of the brain, 4th ed. New York: Oxford University Press. p 255-288.
31. Llinás R, Bloedel JR, Hillman DE. 1969. Functional characterization of neuronal circuitry of frog cerebellar cortex. J Neurophysiol 32:847-870.
32. López-Román A, Ambrosiani J, Armengol JA. 1993. Transient ipsilateral innervation of the cerebellum by developing olivocerebellar neurons. A retrograde double-labelling study with fast blue and diamidino yellow. Neuroscience 56:485-497.
33. Mariani J. 1983. Elimination of synapses during the development of the central nervous system. Prog Brain Res 58:383-392.
34. O'Donoghue DL, King JS, Bishop GA. 1989. Physiological and anatomical studies of the interactions between Purkinje cells and basket cells in the cat's cerebellar cortex: evidence for a unitary relationship. J Neurosci 9:2141-2150.
35. Oscarsson O, Sjölund B. 1977. The ventral spino-olivocerebellar system in the cat. I. Identification of five paths and their termination in the cerebellar anterior lobe. Exp Brain Res 28:469-486.
36. Palay SL, Chan-Palay V. 1974. Cerebellar cortex. Cytology and organization. New York: Springer-Verlag.
37. Ramón y Cajal S. 1911. Histologie du système nerveux de l'homme et des vertébrés, vol II. Paris: Maloine.
38. Rosina A, Provini L. 1983. Somatotopy of climbing fiber branching to the cerebellar cortex in cat. Brain Res 289:45-63.
39. Rossi F, Wiklund L, Van der Want JJL, Strata P. 1991. Reinnervation of cerebellar Purkinje cells by climbing fibers surviving a subtotal lesion of the inferior olive in the adult rat. I. Development of new collateral branches and terminal plexuses. J Comp Neurol 308:513-535.
40. Rossi F, Borsello T, Vaudano E, Strata P. 1993. Regressive modifications of climbing fibres following Purkinje cell degeneration in the cerebellar cortex of the adult rat. Neuroscience 53:759-778.
41. Ruigrok TJH, de Zeeuw CI, Van der Burg J, Voogd J. 1990. Intracellular labeling of neurons in the medial accessory olive of the cat: I. Physiology and light microscopy. J Comp Neurol 300:462-477.
42. Scheibel ME, Scheibel AB. 1954. Observations on the intracortical relations of the climbing fibers of the cerebellum. A Golgi study. J Comp Neurol 101:733-763.
43. Schild RF. 1970. On the inferior olive of the albino rat. J Comp Neurol 140:255-260.
44. Schulman JA, Bloom FE. 1981. Golgi cells of the cerebellum are inhibited by inferior olive activity. Brain Res 210:350-355.
45. Sherrard RM, Bower AJ, Payne JN. 1986. Innervation of the adult rat cerebellar hemisphere by fibres from the ipsilateral inferior olive following unilateral neonatal pedunculotomy: an autoradiographic and retrograde fluorescent double-labelling study. Exp Brain Res 62:411-421.
46. Shinoda Y, Yokota J, Futami T. 1981. Divergent projection of individual corticospinal axons to motoneurons of multiple muscles in the monkey. Neurosci Lett 23:7-12.
47. Shinoda Y, Ohgaki T, Futami T. 1986. The morphology of single lateral vestibulospinal tract axons in the lower cervical spinal cord of the cat. J Comp Neurol 249:226-241.
48. Shinoda Y, Sugiuchi Y, Futami T. 1987. Excitatory inputs to cerebellar dentate nucleus neurons from the cerebral cortex in the cat. Exp Brain Res 67:299-315.
49. Shinoda Y, Sugiuchi, Y, Futami T, Izawa R. 1992. Axon collaterals of mossy fibers from the pontine nucleus in the cerebellar dentate nucleus. J Neurophysiol 67:547-560.
50. Sugihara I, Lang EJ, Llinás R. 1993. Uniform olivocerebellar conduction time underlies Purkinje cell complex spike synchronicity in the rat cerebellum. J Physiol [Lond] 470:243-271.
51. Sugihara I, Lang EJ, Llinás R. 1995. Serotonin modulation of inferior olivary oscillations and synchronicity: a multiple-electrode study in the rat cerebellum. Eur J Neurosci 7:521-534.
52. Sugihara I, Wu H, Shinoda Y. 1996. Morphology of axon collaterals of single climbing fibers in the deep cerebellar nuclei of the rat. Neurosci Lett 217:33-36.
53. Szentágothai J, Rajkovits K. 1959. Über den Ursprung der Kletterfasern des Kleinhirns. Z Anat Entwicklungsgesch 121:130-141.
54. Van der Want JJL, Voogd J. 1987. Ultrastructural identification and localization of climbing fiber terminals in the fastigial nucleus of the cat. J Comp Neurol 258:81-90.
55. Van der Want JJL, Wiklund L, Guegan M, Ruigrok T, Voogd J. 1989. Anterograde tracing of the rat olivocerebellar system with Phaseolus vulgaris leucoagglutinin (PHA-L). Demonstration of climbing fiber collateral innervation of the cerebellar nuclei. J Comp Neurol 288:1-18.
56. Veenman CL, Reiner A, Honig MG. 1992. Biotinylated dextran amine as an anterograde tracer for single- and double-labeling studies. J Neurosci Methods 41:239-254.
57. Voogd J. 1995. Cerebellum. In: Paxinos G, editor. The rat nervous system, 2nd ed. San Diego: Academic Press. p 309-350.
58. Voogd J, Bigaré F. 1980. Topographical distribution of olivary and cortico nuclear fibers in the cerebellum: a review. In: Courville J, de Montigny C, Lamarre Y, editors. The inferior olivary nucleus. Anatomy and physiology. New York: Raven Press. p 207-234.
59. Voogd J, Jaarsma D, Marani E. 1996. The cerebellum, chemoarchitecture and anatomy. In: Swanson LW, Björklund A, Hökfelt T, editors. Integrated systems of the CNS, Part III. cerebellum, basal ganglia, olfactory system. Handbook of Chemical Neuroanatomy, vol 12. Amsterdam: Elsevier. p 1-369.
60. 3H] aspartate. Neuroscience 13:441-468.
61. Yamamoto T, Fukuda M, Llinás R. 1986. Bilateral synchronization of climbing fiber activity. Soc Neurosci Abstr 12:577.